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Can Metformin and Progesterone cause a false positive on an OPK?

KatieDoodle25KatieDoodle25 member
in Trouble TTC
Hey there!

I just started my metformin Friday and progesterone last night, when I did my OPK it was positive. I was wondering if that could possibly be accurate or if the two pills caused the positive?

Thank you for the help! :
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Re: Can Metformin and Progesterone cause a false positive on an OPK?

  • jfb29jfb29 member
    I have PCOS and get false positives on OPKs.  RE told me it just happens for some people and I am one of them, thus I can't use them - you might be the same.  I think it happens more in people with PCOS.

    TTC #1 Since 7/2011

    Me: 30, PCOS with anovulation
    DH: 38, Low Morph & DE
    Rx: Metformin 500mg

    Cycle #1: Clomid 100mg + Ovidrel = No Response, Canceled
    Cycle #2: Clomid 150mg + Ovidrel = No Response, Canceled
    Cycle #3: Clomid 150mg + Follistim + Ovidrel = No response, Canceled

    Cycle #4: Femara 7.5mg + Gonal-f + Ovidrel + IUI = BFP!!!!

     

    ~ EDD 03.26.14 ~

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  • KatieDoodle25KatieDoodle25 member
    Thank you for the response, I too have PCOS, I am taking these meds to treat and help with having a little person. I figured it might be a false positive, as I haven't O'd on my own in some time.
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  • DebateThisDebateThis member

    You should probably ditch the OPKs and start charting your BBT. OPKs and PCOS don't play nice together.

    Good luck.

    Six years of infertility and loss, four IUIs, one IVF and one very awesome little boy born via med-free birth 10.24.13.
    image
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  • NYCGal276NYCGal276 member
    I have PCOS and ovulated a couple of times a year if I was lucky.  When I started metformine alone I ovulated in 6 weeks.  It's definitely possible it's a true positive - but it def could be your PCOS playing tricks with your pee (although - I'm not sure you're gonna O while on Provera).  I'd BD just in case. 
    TTC#1
    Dx PCOS @ 16y.o
    9/2011: unplanned natural conception and MC @ 6weeks Cycle 1: 12/2012: TI & 2000MG Metformin & 100MG Clomid = CP
    Functional Cyst - fixed with 2wks BCP
    Cycle 2: 1/31/13: IUI #1
    Meds:2000MG Metformin, 100MG Clomid, HSG/Trigger, Provera 400mg 2DPIUI
    Stats: SA 20mil & 63% mot/follicles (as per 1/30 u/s): 22, 13, 14
    BFP! Beta #1 13DPiui: 79! Beta #2 15DPiui: 164! Beta#3 19DPIUI: 773! First US scheduled 3/5! EDD Oct 23!
    Lilypie Pregnancy tickers
    S/PAIF Welcome - You girls give me HOPE!
    Herbal Supplements: 1800mg NAC, Fish Oil, Vitamin D, Baby Asprin, Folguard, Multivitamin
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  • KatieDoodle25KatieDoodle25 member
    Can I ask a stupid question, where can you fun information about charting? I want to make sure I am doing it properly.

    I feel a little in the dark with everything! My OBGYN did the necessary testing to determine that I have PCOS and then had her nurse call to tell me I had a prescription waiting at the pharmacy. I have been trying to google and learn more on forums like this, but I am just so lost.

    I want to find a new doctor, I am just not sure where to start since we just moved. I also, just feel a little uneasy talking to friends about everything, because they just got pregnant. It almost makes me feel bad...

    Sorry to unload!
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  • madasm0530madasm0530 member

    imageKatieDoodle25:
    Can I ask a stupid question, where can you fun information about charting? I want to make sure I am doing it properly. I feel a little in the dark with everything! My OBGYN did the necessary testing to determine that I have PCOS and then had her nurse call to tell me I had a prescription waiting at the pharmacy. I have been trying to google and learn more on forums like this, but I am just so lost. I want to find a new doctor, I am just not sure where to start since we just moved. I also, just feel a little uneasy talking to friends about everything, because they just got pregnant. It almost makes me feel bad... Sorry to unload!

    Fertility Friend is a great app to learn charting. They have tools, courses, andmy personal favorite endless hours of chart stalking. You can access through most anyones siggys.

    This is a great place to ask questions and bounce things off people. But, if you have been trying for less than one year, TTGP is probably the place for you. GL!


    hitched 5/2009 -- Me 34, DH 39

    TTC #1:
    dx with POCS 7/2009
    TTC on & off since 1/2012
    September 2012; Surprise BFP - MC
    June - December 2013; Clomid/Femara + Trigger + TI = BFN x 4
    April - May 2016; Femara + TI = BFN x 2
    July 2016 - December 2016; Gonal-F + Ovidren + IUI = BFN x 3
    May 2018 - IVF #1; 8 snowbabies. transferred 1 embryo - CP
    August 2018 - FET #1 -- Healthy Baby Boy  <3

    TTC #2:
    July 2020 FET; beta 1 310, beta 2 1278

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