Third-Party Reproduction

UPDATED: Please pray for our embryos. Just got bad news.

We've known all along that we had five donated embryos, but never knew the quality or real solid details on them. I've asked our clinic about the quality a few times, but the RE said he wasn't sure (and didn't thumb through our 100+ pages of faxed documentation) but  it didn't matter since "they made it to freeze" which is a reassuring good thing. Our donor thought they were all day 5 blasts, but she didn't know for sure either so I left it at and decided I wouldn't worry.

Well, today I got a call from the lab. Apparently of the five, only one is a day 6 blast that had been originally thawed at day 1, grown to a blast then refrozen. The other four are all only day-one zygotes right now. Oh my god. I honestly could just cry at my desk.

The lab person suggested we thaw all four zygotes today, watch them grow and she will have an update for me on them on Saturday. And we will thaw the day 6 blast on the day of our transfer on Monday and pray for the best. She said had no idea what to expect for us since these were frozen over ten years ago and the day 6 will have been frozen twice now. I begged her to take extra special care of them  and she promised she would.

I'm terrified. I could use prayers for these embryos. I feel like I will need to be institutionalized if none of them make it to transfer.

Thanks, ladies. 
 
Feb 8 UPDATE:
 
I got a call from the lab this morning which scared the bejeepers out of me because I wasn't expecting for an update until tomorrow. All four survived the thaw! The lab worker was "quite surprised and impressed" at how well three of them were doing considering their age. She said three were dividing "beautifully" but the fourth had not started dividing yet. She said that fourth one wasn't out of the race and may just be a slow grower. I'll get another update tomorrow. I just wanted to share the news. Sorry for being a PW! I could jump and and down for joy!
 
Thank you all for your continued prayers and support. Things are really looking up!

************ Signature/Ticker Warning ************
Me (32) DH (36) - Finding our way to baby #1
Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
DH: Severe MFI

12/2/11 - IUI #1- BFN 
8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

My ovaries are just for decoration

12/6/12 - Adopted five embryos that had been frozen for over ten years!
2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

6/5/13 - Adopted four new embryos that had been frozen for seven years!
 
9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
9/29/13 - m/c @ 5w1d. :(

11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

Snowflake baby is a girl! 
Our beautiful Snowflake girl arrived on July 22, 2014!   
My embryo adoption blog: Wishing on a Snowflake
 
    image      image 

Re: UPDATED: Please pray for our embryos. Just got bad news.

  • What a shock and I am hoping for the best.

    T&Ps are on the way. 

    Please keep us updated.

     P

    ____________________________

    BabyFruit Ticker

    Lilypie Second Birthday tickers  Daisypath Anniversary tickers
    Breast Cancer diagnosis 12/01/2010 - Survivor and Cancer free as of 03/22/2011
    BFP#1 04/12/201
    1 - fetal demise - MC 05/28/2011
    BFP#2 10/14/2011 - fetal demise - MC 12/13/2011
    BFP#3 05/30/2012 - fetal demise - MC 07/23/2012
    IVF#1 02/14/2013 - 2 Beautiful Blasts transferred
    BFP#4 02/25/2013 - BFP - MC and ectopic 03/06/2013

    IFV#2 07/02/2013 -BFP#5 - 07/07/2013
    1st Beta 07/11/2013 - 483 (9dp5dt) - 2nd Beta 07/13/2013 1006 (11dp5dt)
    1st U/S 07/31/2013 - TWINS! "The Minions"
    IVF#3 BFP#6 09/01/2015 6dp5dt
    1st Beta 09/05/2015 - 105 - 2nd Beta 09/08/2015 335
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  • Ugh I am so sorry this is happening!!! FWIW I was in a similar boat as far as refeezing and all. I had all of my eggs frozen initially  then thawed and ICSI'd when we finally got a good sample. 3 fertilized normally and were frozen day 1 as I started to prepare my lining and all for an FET. All 3 survived the thaw and they were zygotes. One did not continue to grow but the other 2 did and on day 3 one was graded "good," one "average." Things did not end well for me as you know but RE says we may have just been on the wrong side of the odds. At least you have one rockstar already and I would be hopeful that out of the other 4, you would get more because I did and I just had 3. I am keeping my FX for you!! IF is so stressful!!!!
    TTC since June 2011
    DX: DH (30) severe MFI, severely low count & low motility
    Me (32): all clear
    Appt with Urologist 5/21/12: exam, ultrasound, bloodwork all normal.
    Testicular Biopsy with TESE on 6/8/12. good sperm found! (left side only) froze sperm, failed thaw test :(
    Orientation for IVF/ICSI on 6/13/12. Waiting for the green light following biopsy results...results show adequate sperm production both sides.
    2nd SA 6/18/12: sample is "adequate for ICSI"
    Plan: IVF/ICSI July 2012!
    ER: 7/26/12. 15 eggs retrieved, all mature.
    TESE/TESA/aspiration from epididymis, no motile sperm found :(
    froze all eggs, the saga of praying for good sperm continues.
    8/3/12: 2nd opinion from MFI uro on biopsy slides. Suspects "partial late maturation arrest."
    Plan: more SAs, third biopsy/TESE with frozen back-up either from DH or DS.
    SA 8/17/12: Zero sperm
    SA 8/23/12: Zero sperm
    9/26/12: SPERM FOUND! 15 eggs thawed, 12 survived and were ICSI'd, only 3 fertilized normally. Refrozen as embies and will thaw in Nov. Please survive and grow!
    All 3 survived the thaw on 11/15/12!
    FET 11/17/12: transferred 2, one 4B, one 4C. Beta 11/30:BFFN
    moving on to DS
    DIUI#1 2/18/13,50mg Clomid cd 3-7, Ovidrel trigger, Beta 3/4/13: BFN.
    DIUI#2 3/19/13, 50 mg Clomid cd 3-7, Ovidrel trigger, Beta #1 (14dpiui) 4/2/13: BFP!!!! 150. Beta #2 4/4/13: 420 Beta #3 4/8/13: 2691. Beta #4 4/15/13: 15,086
    1st u/s 4/8/13 shows one gestational sac
    2nd u/s 4/15/13 shows yolk sac, fetal pole and early heartbeat
    3rd u/s 4/25/13: measuring right on track. Heart rate 148 bpm
    A/S 7/22/13: IT'S A BOY!!
    PAIF/SAIF Always Welcome
    [IMG]http://i49.tinypic.com/2qmon5u.jpg[/IMG] [IMG]http://i225.photobucket.com/albums/dd243/laurakat24/turkeybaster-1.jpg"[/IMG]Image and video hosting by TinyPic
    BabyFruit Ticker
  • imagestrudel82:

    I'm so sorry to hear. How stressful! Sending lots of thoughts and prayers for your embies!

    And, I may be grasping at straws here, but is it unrealistic to think that the zygotes could end up being rock stars?

    Definitely not unrealistic, but the lab person said she wasn't sure what to expect because they were frozen over 10 years ago with a different type of freezing technology. I'm just praying thats the outcome, hence the plea for prayers. It didn't sound like the lab person was optimistic though, hence my worry.

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • imagemelkel559:
    Ugh I am so sorry this is happening!!! FWIW I was in a similar boat as far as refeezing and all. I had all of my eggs frozen initially  then thawed and ICSI'd when we finally got a good sample. 3 fertilized normally and were frozen day 1 as I started to prepare my lining and all for an FET. All 3 survived the thaw and they were zygotes. One did not continue to grow but the other 2 did and on day 3 one was graded "good," one "average." Things did not end well for me as you know but RE says we may have just been on the wrong side of the odds. At least you have one rockstar already and I would be hopeful that out of the other 4, you would get more because I did and I just had 3. I am keeping my FX for you!! IF is so stressful!!!!

    Thank you, this is reassuring, I appreciate you sharing.

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • Oh no Liz. I am so sorry this is happening to you. Sending lots of prayers your way. Hugs.

    ME:46 MH:44 DE IVF 2014
    Met with RE 4/11. 2 IUI's BFN. DE best option. Switched clinics to do "shared" program. Had to retake all tests and a mamm that put me behind and then on a DE waiting list for 12 months. Picked a donor!! (10/13/13) Got matched. Estimated transfer in December. After 2.5 years of patiently waiting I will finally cycle....can hardly believe it. DE cycle got cancelled. One of her tests came back positive.  Waiting for another donor. Donor picked!! (1/18/14)

    DE IVF #1 (4/26) BFN  DE FET #1 (6/4) BFP! Beta 1=339 Beta 2=852 Beta 3=9957 EDD 2/22/15!!


     

     

         imageimage 
         image   imageimage



  • Praying for you and the lil embryos!
    BFP #1 3/27/07-M/C 8weeks 5/3/07 "Life is not measured by the number of breaths we take, but by the number of moments that take our breath away." 2/4/13 IUI #1+trigger=BFP!!!  DD born Oct. 9, 2013 via c-sectionAnniversary

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  • Sending many T&P's for your 5 little frosties!!!

    Me: AMA, DOR, undetectable AMH, carrier of SMA, MTHFR homozygous C677T, high cytokines, low IGg B cells, Factor XIII V34l mutation, High Anti-Phosphatidylethanolmine, borderline hypothyroid and mildly insulin resistant.

     

    MH: No known issues, aside from MTHFR.

     

    Recommendations from RI: LIT, Humira, IVIG, Lovenox, Baby Aspirin, Folic Acid, Low-dose synthroid and Metformin.

     

    Currently taking:  Pre-Natal vitamins, Foltanx, Low-dose synthroid and Metformin. 

     

    When cycling also taking: Baby Aspirin, Lovenox, Humira and IVIG.

     

    TTC since 7/11/09..with medical intervention starting in 2010, including 4 failed IVF's and 6 failed IUI's...only "success" was a chemical pregnancy in 11/2012 (credited to use of DE).

    FET #1 (11th cycle) on 8/23/13 = BFN.

    FET #2 (12th cycle) Transfer of last two (day 6) donor egg blasts on 1/22/14 = BFP, EDD = 10/10/14 (please stick little BOY!)

     

    My favorite breed:

     

    image

    ***PAIF/SAIF always welcome***

  • I'm sure that was shocking news to receive. Lots of thoughts and prayers your way!! Fingers crossed for you and your embies!! 

    ((Hugs))  

    Baby Birthday Ticker Ticker
    DD conceived with no issues, but born at 33 weeks due to PPROM
    loss #1-06/2010 loss #2-2/2011 loss #3-5/2011
    07/2011 dx with a Balanced Translocation
    9/2011-decided on domestic infant adoption 10/2011-signed with an agency and getting ready for homestudy :)
    12-2012-after being with our agency over a year and only shown to EM once we decided to talk with RE about DEIVF. Thru a crazy sequence of events we decided to go for it and we picked a donor MUCH quicker than anticipated
    1/13/2013-started lupron with anticipated transfer in mid Feb.
    ER 2/15 resulted in 15 eggs/10M/6F with ICSI.
    2/18 transferred 1-8cell and 1-9cell embie. Snuggle in little embies.
    positive on HPT 6dp3dt. Could this really be IT?!?! Beta 14dp3dt=2440. U/S scheduled for 3/20. Pregnancy Ticker
  • My heart goes out to you. Mine just sank reading your news. Sending them tons of growing vibes. T&Ps you make it to transfer.
    Pregnancy Ticker
  • I'm so sorry you got this news!  That must have definitely been a shock!  I will just be praying that they grow beautifully and that you have some good quality embryos to transfer.  
    TTC with DOR, low morphology, fertilization issues
    IVF#1 Oct 2009 (CCRM) - BFN
    IVF#2 March 2010 - Poor response/cancelled
    DE IVF#1 Aug 2010 - BFN
    DE IVF#2 Dec 2010 - Transferred 1, 2 frozen - BFP!
    TTC#2 FET Jan 2013 - Transferred 1 - BFP!

    Baby Birthday Ticker Ticker Baby Birthday Ticker Ticker
  • I'm sure that was shocking. I hope everything turns out better than expected. Thoughts and prayers for you and your embryos.
    For DD - IVF/ICSI #1 - BFP / For DS - dIUI #1 - BFP Dx:severe MFI-Y Chromosome Microdeletion Isabel born 10-15-08! / Baby Boy EDD July 2013 imageLily  pie Fifth Birthday tickers Lilypie Pregnancy tickers
  • That is awful.  I'm so sorry. Fingers crossed that your day 6 is the one!
    Married Since 09/2006, TTC Since 09/2010 
    DX: Unexplained infertility, DH normal 
    3 Femara cycles - Oct, Nov, Dec 2011, all BFNs 
    IVF #1, ER 2/15 (5R, 4M, 4F), ET 2/18, Beta 2/29 = BFN :( 
    Follistim + IUI on 6/25 = BFN 
    Home Study Finalized 8/14/12! Profile Active - 8/17/12! 
    Officially Matched 8/29/12, Our perfect angel born 9/25/12! 
    Biggest surprise ever, unexpected BFP on 4/12/13! 

     Our Angel through Adoption
     Lilypie Third Birthday tickers


    Our Little Miracle
    Lilypie First Birthday tickers
    image
  • T & P for your little embries!!
    TTC since 10/09 Me-43 DH-44 RE and testing 10/10-11/10, Recommending IVF 1/11 New RE AMA and DOR-DH low motility IVF #1.1 cancelled 3/11 due to poor response IVF #1.2 May 2011, one perfect 8-cell embryo, 3dt-BFN, IVF #2.1 Converted to IUI d/t poor response. New RE 9/2011. IVF 2.2 completed using HGH,EPP,DHEA, Q-10 and accupuncture. Transferred one 8-cell, grade one embryo on 10/19. BFP 10/31/11 Chemical pregancy on 11/2/11. Started stims for IVF #3, our final try, on 12-2-11. ET on 12/18. Transferred 3 Grade A embryos-BFFN Planning DE IVF, late March/early April- Donors ER expected to be 4/2-4/4. PAIF/SAIF welcome
  • T&Ps' that everything works out! Left Hug

    April 2013 DE IVF= BFN

    September 2013 DE IVF (Fingers Crossed) = BFFFN! again...

    October 2013 FET of our last 2 = Beta Hellzz for 6-7 Weeks. M/C

  • Hope everything is ok and the little embies grow, grow, grow!
     
    Lilypie Third Birthday tickers
     
     
    Lilypie Pregnancy tickers
  • Great update! Keep dividing lil guys!
    Pregnancy Ticker
  • Great update!!
    TTC with DOR, low morphology, fertilization issues
    IVF#1 Oct 2009 (CCRM) - BFN
    IVF#2 March 2010 - Poor response/cancelled
    DE IVF#1 Aug 2010 - BFN
    DE IVF#2 Dec 2010 - Transferred 1, 2 frozen - BFP!
    TTC#2 FET Jan 2013 - Transferred 1 - BFP!

    Baby Birthday Ticker Ticker Baby Birthday Ticker Ticker
  • Oh this is great news! FX your take home baby is getting ready for a happy 9 months of warmth after being cold for so long!
    Lil'mamaz was born on Aug 21, 2014! She's PERFECT!

    It's been a long road to here...
    Me (43) and J (45) - same sex couple. And we don't feel 40+!
    June'12 - First RE Visit
    Sept. '12 - Tubes removed
    Dec. '12 - Donor Egg/Donor Sperm IVF Cycle - 4 good embies!
    Dec. '12 - Fresh transfer, BFP! EDD 8/29/13
    Mar. '13 - Missed m/c at 16w1d, baby boy stopped growing at 15w4d
    Loss due to umbilical cord clot...baby was perfect. :(
    Jul '13 - FET#1 - c/p
    Sept. '13 - FET#2 - BFN
    Dec.' 2, 2013 - FET#3 with our last chance embie - BFP!!!
    Dec' 26, 2013 - hb!!
    EDD 8/20/14 with a baby girl!
    Little S was born on 8/21/14 - 8lb, 14 oz and 20 inches long.
    We live in Seattle and used SRM for our donor egg IVF cycle


    imageimageimageimage

  • That is fantastic!  I'm so happy you got some great news!
     
    Lilypie Third Birthday tickers
     
     
    Lilypie Pregnancy tickers
  • So happy to hear the good news...and continued luck/growing vibes for your upcoming transfer!!

    Me: AMA, DOR, undetectable AMH, carrier of SMA, MTHFR homozygous C677T, high cytokines, low IGg B cells, Factor XIII V34l mutation, High Anti-Phosphatidylethanolmine, borderline hypothyroid and mildly insulin resistant.

     

    MH: No known issues, aside from MTHFR.

     

    Recommendations from RI: LIT, Humira, IVIG, Lovenox, Baby Aspirin, Folic Acid, Low-dose synthroid and Metformin.

     

    Currently taking:  Pre-Natal vitamins, Foltanx, Low-dose synthroid and Metformin. 

     

    When cycling also taking: Baby Aspirin, Lovenox, Humira and IVIG.

     

    TTC since 7/11/09..with medical intervention starting in 2010, including 4 failed IVF's and 6 failed IUI's...only "success" was a chemical pregnancy in 11/2012 (credited to use of DE).

    FET #1 (11th cycle) on 8/23/13 = BFN.

    FET #2 (12th cycle) Transfer of last two (day 6) donor egg blasts on 1/22/14 = BFP, EDD = 10/10/14 (please stick little BOY!)

     

    My favorite breed:

     

    image

    ***PAIF/SAIF always welcome***

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