Infertility

2nd monitoring appt, i am worried about e2 levels!!

i am getting more follicles of a good size, but my e2 levels are low, which they were the last ivf.  last was 1000 at retrieval, which wasnt corresponding with the amount of larger follicles i had.

this past monday it was 100, but i had a few 14mm size (and 8 or so 6-10). =/  my dr is going to try to let me go a day or two longer to see if letting them go a bit bigger will help . the problem is i already have a 19 and 18 and have to try to push this until Monday. i am doing ganirelex i just don't want them to go overdue so to speak.   while doing injects only i NEVER had an e2 issue, so i have no idea where this is coming from.  My bloodwork is also showing as normal on all counts, so my lack of response and weird e2 is confusing me.  any thoughts?

 I am so worried this means i am going to have crappy egg quality.  My last IVF i had two great looking blasts, but this doesnt necessarily mean great egg quality does it?   my dx has always been PCOS only, so this is all throwing me a curveball ugh


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Re: 2nd monitoring appt, i am worried about e2 levels!!

  • I don't have any advice but I hope they figure it out!
    **Warning: Losses and living child mentioned**
    BFP#1 1/31/12, EDD 10/6/12 Harrison Gray born sleeping @ 18w6d. You changed our lives little guy.
    BFP#2 EDD 10/29/13, C/P 2/25/13, Bye little Ish, we barely got to know you.
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  • I'm sorry you are having to deal with this :( 

    No advice, but I hope your RE can figure something out fast!  

    Me: 37, DH: 35 :: TCC since 2/11 SA: Perfect! CD3  HSG = Blocked Right Tube
    April- Femara 2.5mg + Trigger + IUI = BFN   May- Femara 5mg = CX - No Response on Left = BFN
    June- Femara 7.5mg + Trigger + IUI = BFN  August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
    September- Femara 5mg = CX - No Response on Left = BFN  October- 100mg Clomid + Trigger + TI = BFN
    IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176  c/p @ 4w4d
    FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
    IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
    FET #2 Cancelled, Right Tube Developed a Hydro  8/28 Hydro & Scar Tissue Removed  Cleared for FET
    FET #2.2 Scheduled for September 20th
    2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
    2015- 2 failed FET. We are done
    SURPRISE! BFP 8/8/16   EDD 4/1/17

     
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  • My e2 never got above 21, so I don't have any advice but I hope that things improve and the e2 catches up. :)

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
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  • You could just be a slow starter plus the Ganirelix will falsely lower your e2 levels so it could be higher essentially than it seems to be. Especially since you have some follicles of larger size, I'd venture to guess that's the case.  What was your e2 today? Since its only your 2nd appt. I wouldn't worry just yet...

    And yes, you're right, great looking blasts don't necessarily mean great quality...at least thats what my RE tells me based on the fact that I've had 2 out of 3 cycles with "perfect" embryos but all BFNs.

    Me: 33, Endocrine issues & FVL       DH: 32, Nothing 
    NTNP 2009-2012         TTC since 2012:
    • Clomid, 2 IUI cycles, and 5 IVF cycles = BFN
    • FET #1   August 2013 = BFP!     EDD 5/11/14
    • Jack dx at 19w1d with Dandy Walker on 12/16/13
    • Severe Pre-e /HELLP set in Jack born sleeping at 20w1d on 12/23/13
    • FET #2 --July 2014  BFP!  ---  EDD  4/5/15

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  • No advice, but lots of *hugs* and good luck!  I hope you get some answers, and everything works out!
    TTC #1 ♥ since 1/11 
    BFP #1 8/21/11 - EDD 5/1/12 - M/C 9/25/11 ♥ BFP #2 11/17/11 - EDD 8/1/12 - C/P 11/20/11
    DH (37) SA = mediocre  Me (31) Low AMH/DOR, Septate Uterus (repaired via Hysteroscopy)
    IUI 1-3 = 3 BFNs ♥ IVF 11/12 = BFFN :( ♥ IUI 4 + Injects 1/13 = BFN :(IUI 5 + Injects = cancelled due to cyst
    BFP #3 - 3/9/13 ♥ EDD 11/21/13 Break cycle miracle! ♥ Stick baby, stick!!  IT'S A GIRL!
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