Infertility

Lining & life woes vent

1. So my green light monitoring appt this morning for PIO and FET on 2/4 didn't go as planned.  My lining is still at 5.1 (5.14 to be exact) which what it was on Friday and close to where it was before I even started estrogen.  I haven't gotten my estrogen level or talked to the nurse yet today but I am not responding.  Why won't my lining work with me here?! 

2. My dad got diagnosed with bladder cancer in December and went in for his cardiac clearance appt for the surgery.  The cardiologist wouldn't clear him without a cardiac catherization.  He went in for that and I am thinking that the most they would do would be put in a stent.  Nope, he needed open heart surgery for a quadruple bypass.  So I flew home 2 weeks ago for that.  Luckily, he is home from the hospital and doing fine for the circumstances. 

I was just really hoping that I would get the green light for the FET on Monday and give the family some much-needed good news in the near future.  I am hoping a grandchild will give my dad more motivation to abstain from cigarette smoking.  Hopefully, that will still happen soon.

END vent...

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Married June 2011 Dx: anovulatory due to prolactinoma (1.5cmx 1.5cm in 2006)
April 2012: MRI- questionable cyst 8mg by 12mm in pituitary ; referred to RE by Ob-gyn after amenorrhea x 4+ months, provera ineffective, low estrogen level
cycle 1: May 2012, clomid 50mg; cycle cancelled, thin lining, no response
cycle 2: June 2012, femara 5mg; cycle cancelled, no response
cycle 3: July 2012, femara 7.5mg; cycle cancelled (largest folli on Cd12 & cd 16: 11, lining 4)
Repeat MRI July 25,2012- Cyst unchanged, likely old infarction.
Aug. 8: met with RE, move to injectables if HSG and SA normal
Aug. 23: HSG all clear; DH- perfect
Switched to a new RE in early Sept. IVF here we come
Genetic testing reveals: Fragile X- Intermediate risk/grey zone.
IVF#1: ER 11/30: 14 retrieved, 10 mature, 7 fertilized. E2 prior to trigger 5200. Decision made to freeze 6 embryos and transfer later due to OHSS.
IVF#1.2/FET #1: estrogen injects start 1/18, FET delayed to try to thicken lining. lining 5.4mm. FET- 2/18- transferred one 3AA expanded blast. BFP 5dp5dt. Beta #1- 2/27 9dp5dt- 102.27 beta #2 3/1: 147 :(, beta #3 3/4: 268 told to stop meds and let nature take its course. requested 4th beta (3/6); Beta hell for 2 months.

FET # 2: endometrial scratch 5/6, added estrace vaginally and ASA to delestrogen and PIO. June 10- transferred one 4AA hatched embryo, BFP 4dp6dt, Beta 1 (9dp6dt) 187, Beta 2 (11dp6dt): 412; Beta 3 (15dp6dt ): 4452. U/S #1- one beautiful embryo with a heartbeat of 133 at 7 weeks.  8 weeks: heartbeat 156. EDD 2/26/2014: born 2-3-14 induced due to Pre-E and HELLP at 36w5d.

12/1: met with RE to discuss trying for #2


Re: Lining &amp;amp; life woes vent

  • I'm so sorry! (((hugs))) I hope you hear from your nurse soon. Hoping the best for you!
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  • Hope they figure everything out for you!  What are you on for estrogen?  For my 2nd & 3rd FET, I started on pills 3x per day, and after my first monitoring appointment, they had to add the patches - 2 every 3 days.

    My TTC Journey:
    Dx: Hypothalamic amenorrhea / mild PCOS (Pretty much a hormone/ovulatory disorder)
    Progesterone to induce period w/ the goal of Clomid - never got period (September 2011). Referred to RE.
    Femera - never responded to the meds (December 2011)
    Clomid with TI - BFN (February 2012)
    Injectables (Menopur) - hyperstimulated/canceled (March 2012)
    Injectables #2 (Menopur) with TI- BFN (May 2012)
    IVF - OHSS (transfer canceled), but 11 frozen! (June 1012)
    FET - 1 transferred on 8/09/12. Beta#1 (11dp5dt): 350.3; Beta#2: 365; Beta#3: 157. Biochemical pregnancy.
    FET # 2 - 1 transferred on 11/01/12. Beta#1 (11dp5dt): 337; Beta#2: 769. BFP!!! 1st ultrasound 11/28/12 showed heartbeat, but measuring 5 days behind. 2nd ultrasound 12/05/12 - miscarriage.
    FET # 3 - 1 transferred on 1/24/13. Beta#1 (11dp5dt): BFN.
    FET # 4 - 2 transferred on 3/21/13.  Bet #1 (11dp5dt): 660; Beta#2: 1,300.  Miscarried at home @ 6 weeks.

    FET # 5 - 2 transferred on 7/12/13.  Beta #1 (10dp6dt): BFN.
    Attempted an IUI in late August 2013, but didn't respond well.
    IVF #2 with PGS - Stims started 10/28 with retrieval on 11/11.  Of 14 mature eggs, 10 fertilized, 4 made it to Day 5 & 1 made it to Day 6. We did PGS on the Day 5 embryos, and 3 of 4 were normal. Had ET on 11/17. Beta #1 (8dp6dt): 203. Beta #2 (10dp6dt): 618. We since had two ultrasounds & on 12/19, our RE released us to the OB.  On 1/02/14, we had our first ultrasound with the OB where we heard the heartbeat.  We are so thankful for the blessing & crossing every finger & toe for a healthy & successful pregnancy.

    photo JuneBugs_IFbump.jpgimageimage

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  • Oh no. I'm so sorry about your lining and your dad. I truly hope you get good news on both fronts. ((Hugs))
    Oct 13 April Siggy: Bunnies
    The 33 Most Important Bunny GIFs On The Internet


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    DS born on 9/30/13 from IVF #1.2!
      Lilypie - (xNS5)
  • I am so so sorry for you bad news. :( Hoping your dad is doing well and your lining cooperates soon! 
             

            

    *****Siggy/Ticker Warning*****

     Me (34)- no issues found MH (36)- MFI due to Vericocele. Straight to IVF w/ICSI 9/12, Antagonist. 9R, 7M, 5F = BFN c/p,  New RE for IVF #2- 1/13., Long Lupron. ER on 1/22 -10R, 9M, 9F. Transfer on hold due to overstimming. FET in Feb. 2 frozen blasts. Another BFN & another c/p. RPL testing all negative besides MTHFR gene, vericocle repair surgery 4/12/13-Bilateral Grade 3 Vericocele found & fixed, IVF #3 with PGS  4/13- 11R, 9M, 9F. Transferred 2 normal=BFN, 3 normal on ice. CCRM-here we come! ODWU-All test results normal. EPP in August. 21R, 20M, 19F. 12 blasts biopsied & frozen for CCS testing. Results showed 11 normal! FET Oct. 30. 2 5d 4AA blasts transferred. First ever BFP!!! Beta 1=216, Beta 2=870 1st U/S=It's TWINS!!! It's a BOY and a GIRL!! Everyone Welcome!!! 
                                       Image and video hosting by TinyPic Image and video hosting by TinyPic

                         Pregnancy Ticker
  • Sorry you're having issues with your lining. Have you had issues before? I hope they can do something to thicken it up.
    **Warning: Losses and living child mentioned**
    BFP#1 1/31/12, EDD 10/6/12 Harrison Gray born sleeping @ 18w6d. You changed our lives little guy.
    BFP#2 EDD 10/29/13, C/P 2/25/13, Bye little Ish, we barely got to know you.
    BFP#3 EDD 12/21/13, Baby Boots born 11/23/13 My rainbow baby!
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  • Wow. I'm so sorry you have to go through this. T&P for you and your dad.






          


     TTC since 9/10 consult 1/12 All testing came back fine Diagnosed with Unexplained infertility -3 medicated IUI's All BFN IVF - ER 11/14 24R, 15M, 13F ET 11/19, BETA 11/28 BFFN --Next step FET in Jan ET scheduled for 1/24. Beta #1 350 Beta #2 735. U/S Hell. miscarriage D&C at 9weeks. FET #2 ET 5/28 cancelled FET# 2.5 6/26 ET Beta 7/5 302 7/7 Beta #2 632 Everyone welcome



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    Baby Birthday Ticker Ticker
  • I'm so sorry you have to go through all this. I hope your lining catches up and gives you a break.
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  • Thanks everybody!  I have had lining issues in the past.  For my fresh cycle when my estrogen went sky high, my lining only went up to 7mm.  I just talked to the nurse who wants me to continue on IM estrogen (0.4 cc).  My e2 level was 878.  RE wants to give it another week.  He thinks that maybe my lining won't get thick.  He may still do a transfer a week from Monday (2/11) even if the lining doesn't get to 8.  FX I don't get cancelled.  The only good news she could tell me was that it is triple layer.   I asked if there was anything we could add to help the lining and she said no and brought up that even when I was in OHSS my lining only made it to 7.

    <Image and video hosting by TinyPic
    Married June 2011 Dx: anovulatory due to prolactinoma (1.5cmx 1.5cm in 2006)
    April 2012: MRI- questionable cyst 8mg by 12mm in pituitary ; referred to RE by Ob-gyn after amenorrhea x 4+ months, provera ineffective, low estrogen level
    cycle 1: May 2012, clomid 50mg; cycle cancelled, thin lining, no response
    cycle 2: June 2012, femara 5mg; cycle cancelled, no response
    cycle 3: July 2012, femara 7.5mg; cycle cancelled (largest folli on Cd12 & cd 16: 11, lining 4)
    Repeat MRI July 25,2012- Cyst unchanged, likely old infarction.
    Aug. 8: met with RE, move to injectables if HSG and SA normal
    Aug. 23: HSG all clear; DH- perfect
    Switched to a new RE in early Sept. IVF here we come
    Genetic testing reveals: Fragile X- Intermediate risk/grey zone.
    IVF#1: ER 11/30: 14 retrieved, 10 mature, 7 fertilized. E2 prior to trigger 5200. Decision made to freeze 6 embryos and transfer later due to OHSS.
    IVF#1.2/FET #1: estrogen injects start 1/18, FET delayed to try to thicken lining. lining 5.4mm. FET- 2/18- transferred one 3AA expanded blast. BFP 5dp5dt. Beta #1- 2/27 9dp5dt- 102.27 beta #2 3/1: 147 :(, beta #3 3/4: 268 told to stop meds and let nature take its course. requested 4th beta (3/6); Beta hell for 2 months.

    FET # 2: endometrial scratch 5/6, added estrace vaginally and ASA to delestrogen and PIO. June 10- transferred one 4AA hatched embryo, BFP 4dp6dt, Beta 1 (9dp6dt) 187, Beta 2 (11dp6dt): 412; Beta 3 (15dp6dt ): 4452. U/S #1- one beautiful embryo with a heartbeat of 133 at 7 weeks.  8 weeks: heartbeat 156. EDD 2/26/2014: born 2-3-14 induced due to Pre-E and HELLP at 36w5d.

    12/1: met with RE to discuss trying for #2


  • Sorry you're going through all this stuff now...glad your dad is doing better.  I hope your lining catches up...don't know what they have you on for estrogen, but I've read some stuff that vaginal estrogen *creams* might work better than the patches or anything oral.  Someone here (sorry I forgot who) is using vaginal viagra and it seems to be working...any chance they can throw that on board?  Good luck!
    Married 2007
    3 Clomid IUIs -- BFNs
    IVF #1 never made it to transfer
    On "egg health" cocktail DHEA/CoQ10/FRC/Pregnitude/Melatonin
    Starting IVF #2 for Feb 2013
    Follistim/Menopur/Ganirelix
    Cancelled mid-cycle due to high P4 levels early on.
    OCPs again for IVF 2.5 mid-March. IVF 2.5 transferred two "gorgeous" 5-day blasts and BFFN. Even REI is baffled
    On indefinite hold until a huge stroke of serendipity led me to IVF 3 May 2014
    Testing found positive cardiolipins/APS, now on lovenox and intralipid infusions
    Transfer of 2 5-day blasts and (FINALLY) BFFP!! 1st ultrasound shows two sacs and two HB, but one is sluggish, almost expecting vanishing twin Subsequent ultrasound confirmed vanishing twin, but my other Little critter looks fantastic!
    "You may have to fight a battle more than once to win it."
    -- Margaret Thatcher


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  • I'm sorry your lining isn't thickening up like it's supposed to. FX you hear from your nurse soon and it just means you're delayed and not cancelled. 

    And I'm glad to hear your dad is doing better after his bypass. That must have been very scary for you and your family.

    I want you to get some good news here too! *HUG* 

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
    My embryo adoption blog: Wishing on a Snowflake
     
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