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IVF-3 days of stims, first monitoring appt: 14mm follicle.

CousinVickiCousinVicki member
in Infertility

and a bunch of other 6-10ish range.   I am already starting ganirelex for the rest of the week, but of course i am getting super nervous i am going to have this one dominant follicle (this happened before) and get cancelled.   he is dialing back my gonal-f to slow it down a bit but i hope the others catch up!!!  anyone else have this so early?   i am always a fast responder, but this doesnt usually bode well. 

 

 


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Re: IVF-3 days of stims, first monitoring appt: 14mm follicle.

  • chucktgirlchucktgirl member
    CousinVicki, I did have that my last IVF cycle. One was huge before all others. I think it made it to a whopping 24 by my ER. I had a bunch of slackers that they were trying to bring up. I asked what would happen, and they said they would jus let that one go and focus on the other follicles that were more similarly grouped in size below it. I think they would have even let me stim one more day if it hadn't been for the big guy...but they never mentioned canceling as an option at all. Good luck!

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    My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.

    PAIF/SAIF Welcome!
    Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins    .
    First natural PG 9/27/11; mc: 1/20/12
    First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
    IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right  & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
    ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
    IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13
    ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
    IVF #3:     NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
    ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0.  Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
    IVF #4:     (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
    ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
    ***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...
    IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
    BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
    2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
    2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
    2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
    IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
    5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
    6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
    7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
    EDD 3/18/15!

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  • BootsOrHeartsBootsOrHearts member

    Ugh, sorry. I was told this was a risk but I was taking ganirelix early (from 10 DPO) to prevent it. When did you start the gani? Maybe it needs to be earlier? Sorry I don't really have much insight, but maybe it's worth asking about.

    I hope they can hold it off and get some more growing!

    **Warning: Losses and living child mentioned**
    BFP#1 1/31/12, EDD 10/6/12 Harrison Gray born sleeping @ 18w6d. You changed our lives little guy.
    BFP#2 EDD 10/29/13, C/P 2/25/13, Bye little Ish, we barely got to know you.
    BFP#3 EDD 12/21/13, Baby Boots born 11/23/13 My rainbow baby!
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  • teridanielleteridanielle member
    I just had a very similar situation with my stimming protocol this go round.  After three days I was very stimulated, including a 12mm follicle.  I was dropped from 150 of follistim to 50 and put down to two, instead of three, vials of menopur.  Your RE will adjust accordingly.  I had a dominant follie my last go round, but was cancelled (strangely for oversuppression).  I'm doing well with this does of meds and at 8 days just started my ganirelix.  GOODLUCK.  All will go well!

    All Welcome

    Me: 29 DH: 30

    IF DX Endo Stage III/IV SA: PERFECT!

    7/16/2011 Married handsome hubby!
    9/2012 Lap/Hystercopy DX w/ Stage III endo
    Bilaterial Uterine Suspension/D&C/HSG
    HCG/D&D on R/L ovaries/chromaltubation/Uterine Polyp
    10/2012 RE consult. DX move straight to IVF
    IVF #1 11/27/2012
    IVF #1 Cancelled for Low Response and Converted to IUI #1 --- BFN

    IVF #1.2 BCP 12/29 Stims 1/21 w/ New Protocol - Antongonist (225 Menopur, 150 Follistim, & Ganirelix)
    ER 2/2/13 11R,9M,8F -- ET 2/7/13 2 Beautiful Perfect Blasts/5 made it Freeze! -- 2/12/12 +HPT -- 2/14/13 Beta #1 71 -- 2/18/2013 Beta #2 521 YAY! Let this be our take home baby!

    4/21/13 Massive Hemorrhage from unDX placenta previa.  Bed Rest for 7 months.

    10/17/13 Gave Birth to our 8lb 2oz baby boy! 

    8/30/15 Started Meds for FET schedule on 10/13/15

    10/13/15 TX two great blasts.  Beta scheduled for 10/22/15

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  • Crystal120410Crystal120410 member
    I dont have any advice just wanted to say good luck.
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  • JSM0801JSM0801 member
    I think it is completely normal to have one or even a few dominant follicles. I don't know why they would cancel you because of that though. If it gets too big, I would think they would just sacrifice it for the others. But, it still might be completely fine, even if it is big. I just had a 26, 24, 2x23's in my batch when I triggered, and I was panicked they would be post mature, but they were all perfect and fertilized normally. Hopefully it will be fine! GL!!!
             

            

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     Me (34)- no issues found MH (36)- MFI due to Vericocele. Straight to IVF w/ICSI 9/12, Antagonist. 9R, 7M, 5F = BFN c/p,  New RE for IVF #2- 1/13., Long Lupron. ER on 1/22 -10R, 9M, 9F. Transfer on hold due to overstimming. FET in Feb. 2 frozen blasts. Another BFN & another c/p. RPL testing all negative besides MTHFR gene, vericocle repair surgery 4/12/13-Bilateral Grade 3 Vericocele found & fixed, IVF #3 with PGS  4/13- 11R, 9M, 9F. Transferred 2 normal=BFN, 3 normal on ice. CCRM-here we come! ODWU-All test results normal. EPP in August. 21R, 20M, 19F. 12 blasts biopsied & frozen for CCS testing. Results showed 11 normal! FET Oct. 30. 2 5d 4AA blasts transferred. First ever BFP!!! Beta 1=216, Beta 2=870 1st U/S=It's TWINS!!! It's a BOY and a GIRL!! Everyone Welcome!!! 
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