Apologies upfront, I don't do so well with the acronyms...
I am looking for some advice. This August will be two years that we have been trying (under DR supervision). We had our 11th, yes 11th, IUI, yesterday. This cycle was the first time with FolliStem injections and Femara. Among a slew of other meds helping the cause. Are we CRAZY to keep at the IUI for this long? We follow the rule of 3 and keeps adding in additional helpers, but I don't know at what point we should start thinking about the IVF. All of our testing has left the DR's confident we can get pregnant with IUI, but I'm starting to lose my MIND, FAITH, PATIENTS and trust that this is the right path. Wondering if it's time to request the move to IVF. I know no one can give me the right answers, but just looking for some opinions.
Re: Am I CRAZY...
The guidelines I've seen are that after 6 failed IUIs, it's time to move onto IVF. But, I think that's just a rule of thumb and ultimately you and your RE need to decide on what to do next.
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BFP#2 EDD 10/29/13, C/P 2/25/13, Bye little Ish, we barely got to know you.
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2 do you have any IVF coverage?
If no IUI/IVF coverage, I'd stop the IUIs and just save for IVF.
If you do have IUI coverage, but no IVF, I would keep doing IUIs and save for IVF. This is what we're doing.
If you have both IUI and IVF coverage, I'd do IVF.
Hope that helps :
All of this exactly.
Out of curiosity though, you've done 11 IUIs since June last year? Dude!
***EVERYONE WELCOME***
Mine recommends you move on after 6. After 6 I was ready to move on...11 is A LOT.
Me- 32, DH- 32- TTC for 4 Years
IUIs 1-6 BFN
IVF #1= BFP- M/C
FET- Beta#1: 69, #2: 482, #3: 1088, #4: 28,318, Ultrasound- 1 beautiful heartbeat
It's a boy!
Yes 11 is a TON! We're mentally exhausted. And VERY fortunate that both procedures are covered. I think because after 3 tries, we would change up the meds, I just had high hopes that the next stage would work. But after reading around, sounds like most people don't do as many attempts at IUI that we have. In all honesty, the IVF scares me. I don't know enough about it, but it just does and although we are well aware multiples are a big possibility at this stage, that scares the heck out of me as well.
 In all honesty, the IVF scares me. I don't know enough about it, but it just does and although we are well aware multiples are a big possibility at this stage, that scares the heck out of me as well.
The other part is, I love...LOVE my Dr's. And I whole heartedly trust them and believe they are working as hard as they can to get us pregnant, so I'm not sure why they haven't suggested IVF. My husband and I are both 29, so I feel like maybe that's why.
I had only done 3 IUI's. 1 with femara and 2 with follistim, all BFN's.
How is all your bloodwork/testing? I think at some point I would just take the IVF because there is a better shot. My 3 IUI's were not covered but we just switched insurance so both IUI and IVF is now covered so it was an easier move to choose IVF (RE said we could try one more IUI if we wanted).
If it were me, I would definitely move on. There may be egg or other issues that would only be found out after an IVF.
**TTC #1 Sep 2009-Feb 2013** Me: 33 DH: 32 (healthy, SA = normal)
DX (May 2010) = Lap #1 showed Stage I-II endometriosis. HSG normal. Tx with 6 mo Lupron (which did nothing...) Lap #2 June 2011 to remove endo, uterine fibroid, and polyp
IUI #1-#3 (July-Sep 2011): All Clomid 50 mg + unmonitored IUI = All BFN
October 2011 - April 2012: Outta $$$ (no insurance coverage) = back to tryin' on our own
May 2012 - August 2012: Mental break from trying
October 2012: New OB. Bloodwork normal aside from slightly low progesterone
November 2012: IUI #4: Letrozole 2.5 mg + Novarel trigger + monitored IUI + progesterone = BFN
IVF #1: Long Lupron Protocol,Menopur,Follistim, ER = 2/12/13 27R/26M/23F
2/17/13 Transferred 1 perfect Grade 1 blast. 17 frostbabies.
HPT 7dp5dt: BFP!!! Beta #1 9dp5dt: 108 Beta #2 11dp5dt: 368
U/S #1 3/21: Heartbeat and one perfect bean!! DS born 11/6/13 via c-section
TTC #2 March - August 2015 = all BFNs
Prep for FET #1: Aug 2015: found "mass" in uterus on saline sonogram; scheduled a hysteroscopy to remove.
Sept 2015: Hysteroscopy: mass turned out to be scar tissue(?), all removed. Recheck saline sonogram 2 weeks later showed "stuff" still in uterus (more scar tissue? remnants from surgery? Will see if clears with a period). Recheck saline sonogram 1 week later: all clear! Start Lupron and Estrace. Follow up u/s 2 weeks later: uterine lining only 5mm, add in patches. Follow up u/s 1 week later: uterine lining = 4.3mm (argh!), stop estrace and patches and start estradiol injections twice/week. Follow up u/s 2 weeks later: uterine lining = 5mm Instructed to keep on estradiol injections and recheck in 5 days = lining still at 5mm. Need to make a decision - go for it? Or toss in the towel w/ this cycle and start all over again next year with a new protocol. Decided to go for it as we had 17 frosties; what have we got to lose??
 Instructed to keep on estradiol injections and recheck in 5 days = lining still at 5mm. Need to make a decision - go for it? Or toss in the towel w/ this cycle and start all over again next year with a new protocol. Decided to go for it as we had 17 frosties; what have we got to lose??  
12/2/15 = transferred 1 perfect Grade B blast
12/9/15 = HPT - BFP!!!!
Beta #1 12/11/15: 236 Beta #2 12/14/15: 503 Please stick little one!!!!
U/S scheduled for week of 1/4/16
Thank you all for your honesty and guidance. I think I just need to mentally come to terms with the IVF. I'm going to hope for the best for this cycle and then tell them we are ready for the IVF.
As always, thank you ladies for listening and for making me (us) feel like we're not alone. 
 
Dx PCOS @ 16y.o
9/2011: unplanned natural conception and MC @ 6weeks Cycle 1: 12/2012: TI & 2000MG Metformin & 100MG Clomid = CP
Functional Cyst - fixed with 2wks BCP
Cycle 2: 1/31/13: IUI #1
Meds:2000MG Metformin, 100MG Clomid, HSG/Trigger, Provera 400mg 2DPIUI
Stats: SA 20mil & 63% mot/follicles (as per 1/30 u/s): 22, 13, 14
BFP! Beta #1 13DPiui: 79! Beta #2 15DPiui: 164! Beta#3 19DPIUI: 773! First US scheduled 3/5! EDD Oct 23!
S/PAIF Welcome - You girls give me HOPE!
Herbal Supplements: 1800mg NAC, Fish Oil, Vitamin D, Baby Asprin, Folguard, Multivitamin