Infertility

What's your protocol?

Today is my last day of BCP's!!!!  Baseline on Wednesday and start 10 units Lupron that morning and night, then on Friday start 150 iu follistim morning with the lupron, and 150 follistim and 150 menopur at night with the lupron.  I'm on a microdose flare protocol due to AMH.  

Anyone who is cycling (or close to it) want to share their protocol?  I am always interested in seeing what everyone else is taking.   

Me (37) DH (39); PCOS changed to Unexplained, changed to DOR in 2012 (finally a correct diagnosis!); 
Started TTC 2009 with RE after 6 months.  
Clomid + Trigger x2; 
IUI + Femara x1,
IUI + Follistim x2;
IVF #1 (MDL) February 2013- BFN.
IVF #2 (antagonist) May 2013, First BFP of my life. 
Identical twin miracle BOYS (!!) headed our way- due date is technically 2/4/14 but c section is scheduled for 1/7! 


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Re: What's your protocol?

  • Woo hoo!  I'm on Follistim and menopur for now, ganirelix will come in later and ill be doing PIO which I'm not exactly looking forward to :)

    good luck! 

    Married 2007
    3 Clomid IUIs -- BFNs
    IVF #1 never made it to transfer
    On "egg health" cocktail DHEA/CoQ10/FRC/Pregnitude/Melatonin
    Starting IVF #2 for Feb 2013
    Follistim/Menopur/Ganirelix
    Cancelled mid-cycle due to high P4 levels early on.
    OCPs again for IVF 2.5 mid-March. IVF 2.5 transferred two "gorgeous" 5-day blasts and BFFN. Even REI is baffled
    On indefinite hold until a huge stroke of serendipity led me to IVF 3 May 2014
    Testing found positive cardiolipins/APS, now on lovenox and intralipid infusions
    Transfer of 2 5-day blasts and (FINALLY) BFFP!! 1st ultrasound shows two sacs and two HB, but one is sluggish, almost expecting vanishing twin Subsequent ultrasound confirmed vanishing twin, but my other Little critter looks fantastic!
    "You may have to fight a battle more than once to win it."
    -- Margaret Thatcher


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  • How does ganirelix work?  I've heard of it but don't know what it is.  I am also doing PIO after retrieval.  My trigger shot is also an IM shot so I guess that will be the "test" shot to see how good my husband will be at shooting me in the butt for 2 weeks after ER.  If I am pregnant, I get to switch to crinone if my levels are ok.  They also gave me estradiol tabs to take after transfer, not sure what for.  I just nod my head yes and take what they give me! :) 

     

     

    Me (37) DH (39); PCOS changed to Unexplained, changed to DOR in 2012 (finally a correct diagnosis!); 
    Started TTC 2009 with RE after 6 months.  
    Clomid + Trigger x2; 
    IUI + Femara x1,
    IUI + Follistim x2;
    IVF #1 (MDL) February 2013- BFN.
    IVF #2 (antagonist) May 2013, First BFP of my life. 
    Identical twin miracle BOYS (!!) headed our way- due date is technically 2/4/14 but c section is scheduled for 1/7! 


    BabyFetus Ticker image
  • imageEcarabeo217:

    Woo hoo!  I'm on Follistim and menopur for now, ganirelix will come in later and ill be doing PIO which I'm not exactly looking forward to :)

    good luck! 

    That was my protocol too - it's antagonist. Ganirelix prevents you from Oing early. It comes in a prefilled syringe with quite possibly the most dull needle ever made. At least mine were...

    IM shots get easier with time. I did a combo trigger so one of the three trigger shots was IM and now I do daily PIO shots. I can do them on myself. The hardest part is turning around to reach my own butt. lol. They do hurt more than sub-q shots though.

  • Tomorrow is my last day for BCP.  I've got 75 iu follistim and 75 iu menopur in the am and 150 iu follistim in the pm. My first ultrasound is 2/5.  I've got pio, ganirelix, and estrace too for whenever they tell me!  

    Did I understand correctly that they would do the first u/s even with AF?   

    Me:40 DH: 43 m/c #1 4/8/08 @ 5w::natural
    m/c #2 missed m/c discovered 12/11/08 @ 8w3d :: d&c 12/15/08
    Feb 2009-began seeing an RE:: DX with unexplained IF
    Sept 2009 -2010 TTC using femara ...eventually work called me out of town.
    June 2011 DX with thyroid cancer-forced to put baby making on hold
    11/15/12 IUI #1 BFN and 12/15/12 IUI #2 BFN
    Feb 2013 IVF-BFN:: April 2013 FET-Cancelled:: July 2013 FET-1 frostie
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    image image
  • Hi ladies,

     I am starting Lupron 10 IU on Thursday, then the 9th I start doing Bravelle 300IU and Menopur 75 IU along with continueing the Lupron.


    Me (30) my best friend (38)
    TTTC since "Jan 2011"
    RE appt april 2012
    Dx: PCOS and stage 1 endo
    S/A 19 million, 48 motility, 1 morphology
    6.1 progestrone
    HSG: tubes clear
    clomid 50mg + #1 IUI + trigger 6/9/12 BFN 6/18/12 Clomid 150mg +#2 IUI + trigger: 7/9/2012 BFN 7/18/2012 stage 1: endo removed 8/14/12
    Letrozole 2.5mg+estrogen=cycle cancelled for little to no response
    Follistim 75 (10/15-10/19) follistim 67 (10/20-10/21) cycle cancelled due to over response 9 follies and very thin lining
    ~ IVF #1:BC pills started 10/27~
    ~IVF class schedualed for 11/13~
    ~ Lupron starts Thanksgiving day~
    ~Stims start December 1st~
    ~ER: December 12th ~
    ~ET: December 15th~
    19 R. 12. Fertilized with ICSI, 2 transfered
    only 1 made it to freeze!
    Beta #1 12/27/12 (26)
    beta #2 12/29/12 (78.9)
    Beta #3 12/31/12 (149)
    Beta #4 1/4/13 (48)
    C/P on 1/4/13 @ 5 weeks and 2 days
    ~ IVF #2 ~
    ~ BC pills1/15-2/3~
    ~Lupron beings 1/31~
    ~stims start Feb. 9th~
    ~ER 2/21/13~
    ~14 R, 12 fertilized with ICSI~
    ~1 made it to freeze~
    ~Twin Boys Arrived August 31, 2013
    imageAnniversary
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    P/SAIF Welcome~ everyone welcome
  • I'm on 50 follistim and 150 of menopur at night. I'm 7 days in so hopefully ill start ganirelix on Monday! ER possibly Friday or Saturday!

    All Welcome

    Me: 29 DH: 30

    IF DX Endo Stage III/IV SA: PERFECT!

    7/16/2011 Married handsome hubby!
    9/2012 Lap/Hystercopy DX w/ Stage III endo
    Bilaterial Uterine Suspension/D&C/HSG
    HCG/D&D on R/L ovaries/chromaltubation/Uterine Polyp
    10/2012 RE consult. DX move straight to IVF
    IVF #1 11/27/2012
    IVF #1 Cancelled for Low Response and Converted to IUI #1 --- BFN

    IVF #1.2 BCP 12/29 Stims 1/21 w/ New Protocol - Antongonist (225 Menopur, 150 Follistim, & Ganirelix)
    ER 2/2/13 11R,9M,8F -- ET 2/7/13 2 Beautiful Perfect Blasts/5 made it Freeze! -- 2/12/12 +HPT -- 2/14/13 Beta #1 71 -- 2/18/2013 Beta #2 521 YAY! Let this be our take home baby!

    4/21/13 Massive Hemorrhage from unDX placenta previa.  Bed Rest for 7 months.

    10/17/13 Gave Birth to our 8lb 2oz baby boy! 

    8/30/15 Started Meds for FET schedule on 10/13/15

    10/13/15 TX two great blasts.  Beta scheduled for 10/22/15

  • Yes! The ganirelix needle is awful! And the med itself used to leave me little red welts for a day or two. I don't have a problem giving myself the IM shots...I've done b12 shots in the past...but I know the PIO hurts because its in oil. I have has patients tell me the best bet is to ice first, the. Heat after the shot. And it makes sense, since its oil, the heat helps the medication spread into the muscle tissue instead of staying and leaving a nasty knot. I will also be doing crinone after and estrace, too. 

    Vegas--yup, u/s with or without AF. Fun stuff! 

    Married 2007
    3 Clomid IUIs -- BFNs
    IVF #1 never made it to transfer
    On "egg health" cocktail DHEA/CoQ10/FRC/Pregnitude/Melatonin
    Starting IVF #2 for Feb 2013
    Follistim/Menopur/Ganirelix
    Cancelled mid-cycle due to high P4 levels early on.
    OCPs again for IVF 2.5 mid-March. IVF 2.5 transferred two "gorgeous" 5-day blasts and BFFN. Even REI is baffled
    On indefinite hold until a huge stroke of serendipity led me to IVF 3 May 2014
    Testing found positive cardiolipins/APS, now on lovenox and intralipid infusions
    Transfer of 2 5-day blasts and (FINALLY) BFFP!! 1st ultrasound shows two sacs and two HB, but one is sluggish, almost expecting vanishing twin Subsequent ultrasound confirmed vanishing twin, but my other Little critter looks fantastic!
    "You may have to fight a battle more than once to win it."
    -- Margaret Thatcher


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  • I'm AMH also and doing estrogen priming. I did estrogen patches and ganirelix as suppresants (kinda) and now I'm stimming with 150 gonal-F and menopur twice a day. Of course, I'm only on day 3 of stimming so they might up those dosages yet.
    **Warning: Losses and living child mentioned**
    BFP#1 1/31/12, EDD 10/6/12 Harrison Gray born sleeping @ 18w6d. You changed our lives little guy.
    BFP#2 EDD 10/29/13, C/P 2/25/13, Bye little Ish, we barely got to know you.
    BFP#3 EDD 12/21/13, Baby Boots born 11/23/13 My rainbow baby!
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    January PAL Siggy Challenge: Good Advice
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  • Microdose Lupron here too! I also have a low AMH and responded poorly my first IVF so I'll be starting off on a high dose dose of gonalf 300 and not sure of menopur dose yet.

    Good luck with the PIO! I don't have any experience with that as I've always done crinone. All you ladies who do your IM shots yourself are so much braver than me! The trigger shot is my only IM injection and I can't bring myself to do that one on my own! So kudos to you all!!
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  • My last BCP is Friday and then I go in for my baseline on Saturday.  I'll start follistim and menopur, 75 ius on Tuesday 2/5.  After a certain point, they will add in ganirelix. 
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  • I am low AMH and had a terrible response to first IVF so this round I will be taking 100 mg of clomid and 450 iu(!) of gonal-f. It is interesting and reassuring I guess to see all the other protocols that our out there! I know mine is a bit weird but I actually over responded to clomid so that's why we are using that.
    Me:30 low AMH; DH:30 MFI (count, motility, morphology)
    2 rounds clomid 100 mg -BFN
    IUI#1- 25 mg clomid- July 2012= BFN!
    IUI #2 August = BFN!
    IUI #3 September = BFN!

    IVF #1 November - converted to IUI #4 due to poor response = BFN
    IVF #1.2 February- converted to IUI #5 due to poor response = BFN
    IVF #1.3 April- micro dose Lupron flare with HGH; 14R, 13M, 11F! Transfer of 1 day 5 blast on 4/30, 4 frosties. BFP! Beta #1 9dp5dt= 179; Beta #2 11dp5dt= 442; Beta #3 4106 Stick baby stick!!

    *trying to keep hope*




  • I am on a long lupron protocol. I am on bcp now but will start with 20 units of lupron for 9 days in the am and then go down to 5 unites and add in gonal-f and menopur in the evenings for 10 days.  

    Me: 33 DH: 32 SA#1 low count (6mil) SA#2- now in IUI range!(30mil) Dx:MFI
    11/1- IUI#1,12/1- IUI#2, 1/2- IUI#3 all BFFN
    IVF#1. Long Lupron.ER 3/8 10R,4M,5F. ET 3/3-one 1AB, 2 frosties 5dp5dt-BFP!! Beta 3/25-794 Beta 3/27- 1794
    First u/s 4/8 saw hb. 4/22 missed mc 8w3d. d&c 4/26
    FET #1- bcp start 6/9. ET 7/12. 2 perfect blasts.5dpt-BFP!! 
    Beta 7/24 -1,239!! Beta 7/26- 2569 Beta 7/29- 7120.  U/S 8/7 hb 118! U/S 8/14 hb 143! U/S 8/20 hb 170. Graduated!! Stick baby stick! 


  • I also did micro dose lupron. I did 10 units lupron am and pm, 300 units follistim am and pm, 10 units micro hCG pm. Good luck! 
    Me: 33, Hypothalamic Amenorrhea, DOR (AMH .35), DH: 38, Borderline low morph
    5/09- Off BCP, 5/09-9/09- No period, 9/09-9/10- Lots of Tests & accupuncture
    10/10 and 11/10- 2 rounds of Menopur + TI= BFNS
    12/10-IUI #1 Menopur = BFN
    1/11- IUI #2 Menopur = BFP, 2/11 missed mc at 9 weeks, D&C
    5/11- Operative Hysteroscopy to remove uterine septum
    6/11- IUI #3 Menopur = BFP, 8/11 missed mc at 11 weeks, D&C
    1/12- Lap and Operative Hysteroscopy to remove uterine septum (again) & scar tissue
    2/12- Stint Removal, 3/12 repeat SHG and HSG- showed scar tissue blocking right tube
    4/12- Operative hysteroscopy (again), RE said he can now see right tube (yay!)
    5/12- Stint removal, 6/12 repeat SHG and HSG-both tubes are open!
    8/12- IUI #4 Bravelle = BFN
    9/12-IUI #5 Bravelle = BFN
    1/13- IVF #1, micro-flare protocol, 7R, 6F, 5dt of 2 AA embryos, 1 to freeze = BFP
    Beta #1: 176, Beta #2: 422, EDD 10/8/13- it's TWINS!
    *PAIF/SAIF always welcome*
    Lilypie Angel and Memorial tickersLilypie Angel and Memorial tickers
    Pregnancy Ticker
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  • Lots of differences!  I'm always curious why one body responds one way and another body differently to the same meds/dosage.  Still a weirdly scientific miracle to me.  My RE does not permit me to do my own IM shots (said something about hitting sciatic nerve?) although all my friends IRL who have done IVF have done their own so not sure about this! :) The control freak in me would rather do them myself then trust my husband with a 22 gauge needle. lol
    Me (37) DH (39); PCOS changed to Unexplained, changed to DOR in 2012 (finally a correct diagnosis!); 
    Started TTC 2009 with RE after 6 months.  
    Clomid + Trigger x2; 
    IUI + Femara x1,
    IUI + Follistim x2;
    IVF #1 (MDL) February 2013- BFN.
    IVF #2 (antagonist) May 2013, First BFP of my life. 
    Identical twin miracle BOYS (!!) headed our way- due date is technically 2/4/14 but c section is scheduled for 1/7! 


    BabyFetus Ticker image
  • I've been on lupron for two weeks and I start stims (follistim and menopur) + a lowered dose of lupron tomorrow. Estimated dates for ER are the 8th-11th.Indifferent

    Edited to add: Follistim and Menopur will both be 150iu and Lupron is at 20u now and dropping to 5u. 

    My trigger will be IM, then adding in estrace and PIO (whimper) and god knows what else. I have so many meds in my kitchen right now I'm starting to think I live in a pharmacy.

    Six years of infertility and loss, four IUIs, one IVF and one very awesome little boy born via med-free birth 10.24.13.
    image
  • imageKeephope2012:
    I am low AMH and had a terrible response to first IVF so this round I will be taking 100 mg of clomid and 450 iu! of gonalf. It is interesting and reassuring I guess to see all the other protocols that our out there! I know mine is a bit weird but I actually over responded to clomid so that's why we are using that.


    I didn't respond better, but almost the same when I was doing IUIs with Femara. So I totally get adding in clomid with your cycle! Will you be on any suppressants? Sorry if its in your siggy, I'm on my phone so I can't see. I am not doing any suppressants this cycle and have read about developing lead follies when starting off at high does of meds right off the bat. I am super nervous about that happening with me. Just curious if you were being suppressed or not.
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  • I just got my calendar and didn't talk to the nurses yet but it appears that I'll be on 225 follistim and 10 microdose HCG.
    IVF#1 in March 2013.  BFP!  Due date 12/11/13.
    image Image and video hosting by TinyPic

    Lost my sweet angel...D&C on 6/11/13.

    IVF#2 in September.  BFP!  Due date 6/8/14!
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  •  Ganirelix left little red welts for me too. I thought it was just me. I also have red hives / welts where I do my PIO shots. I bet I should probably ask my RE about that, eh? They specifically told me I can't do heating pads or anything hot near my ovaries or uterus.

    I'm doing PIO and Vivelle Dot. I hate the Vivelle. It gives me a headache. I oddly don't mind the PIO as much. Although I do mind the hives. They are so freaking itchy! It's SO hard not to scratch when I'm doing the shot because it itches so bad. It's worse right while I'm doing it and after then it fades some.

  • SCRN I will be adding Ganirilex for suppression later in the cycle. Hm yeah not sure about developing lead follies- hopefully not! GL!
    Me:30 low AMH; DH:30 MFI (count, motility, morphology)
    2 rounds clomid 100 mg -BFN
    IUI#1- 25 mg clomid- July 2012= BFN!
    IUI #2 August = BFN!
    IUI #3 September = BFN!

    IVF #1 November - converted to IUI #4 due to poor response = BFN
    IVF #1.2 February- converted to IUI #5 due to poor response = BFN
    IVF #1.3 April- micro dose Lupron flare with HGH; 14R, 13M, 11F! Transfer of 1 day 5 blast on 4/30, 4 frosties. BFP! Beta #1 9dp5dt= 179; Beta #2 11dp5dt= 442; Beta #3 4106 Stick baby stick!!

    *trying to keep hope*




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