Infertility

3DT or 5DT?? Which do you feel is better?

So it sounds like my clinic prefers doing 3DT, which is ok I guess. I feel like most things I've read point to 5DT having higher success rates in pregnancy/live birth rates...I guess my thought process is that the longer we can see it's growing the likely hood that it's a strong one! But I dunno, what do you guys think/prefer? Or what have you done?

*Siggy Warning*

TTC since 11/11. 10 months natural= 10 BFN 8/12 First appt with RE 4 semen anaylsis later 1.9 million count, 21% motility and very poor morphology Me- bloodwork, 2 ultrasounds, HSG exam =I'm fine / 3 months of testosterone treatments = 3 more BFN DH bloodwork after 3 months treatment= no change/  

RE says we can continue with hormone treatment for MIF, RE says we can try IUI but doesn't expect the results to be good based on severe MIF/ 

 IVFw/ICSI Cycle #1 1/11/13 Antagonist Protocol IVF Cycle #1 Canceled due to poor response and lead follicle problems. 1/18/13 started Provera to get body back to baseline / take a break to re-evaluate and recoop finances

IVFw/ICSI Cycle #2 4/13/14 Supressed with Estrace for 7 days. / Started injections 4/22/14. Baseline -0 follicles  Started 75iu menapur/150iu follistim, morning and evening injections   ER- 8 Retrieved, 7M, 7F, 5/8 transferred2 Good 8 and 9 cell Embryos. Beta #1 at 11dp3dt  67! I'm pregnant! Beta #2 174! Ultrasound scheduled 6/6/14

Ultrasound on 6/6 confirmed a singleton pregnancy and a heartbeat, although my iradic breathing would allow us to get the rate.  Second ultrasound measured great and got to hear he heartbeat!! 176 bpm Graduating to my OBGYN with our next appointment with them being 7/23/14

 

 
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Re: 3DT or 5DT?? Which do you feel is better?

  • My clinic prefers 3dt unless you have a lot of eggs/embies. And I'm pretty sure that they freeze on day 3 as well. I think there are pros and cons to both transfer dates and I just went with my clinics recommendation.
    Me: 37, DH: 35 :: TCC since 2/11 SA: Perfect! CD3  HSG = Blocked Right Tube
    April- Femara 2.5mg + Trigger + IUI = BFN   May- Femara 5mg = CX - No Response on Left = BFN
    June- Femara 7.5mg + Trigger + IUI = BFN  August- Lap & Hysteroscopy = Blocked & Partially Blocked Tubes
    September- Femara 5mg = CX - No Response on Left = BFN  October- 100mg Clomid + Trigger + TI = BFN
    IVF # 1: Stims 11/30 ER 12/12/12! (10R, 10M, 8F, 2T, 6 F) :: Beta #1- 176  c/p @ 4w4d
    FET #1 February 26th :: Lost 4 to Thaw, Transferred 2 = BFFN
    IVF # 2 Stims 5/10 ER 5/21 (15R, 13M, 13F, 2T, 7F- 6d3 & 1d5) :: Beta # 1- 15 c/p @ 4w
    FET #2 Cancelled, Right Tube Developed a Hydro  8/28 Hydro & Scar Tissue Removed  Cleared for FET
    FET #2.2 Scheduled for September 20th
    2 Thawed, 2 Transferred! Beta #1- 96, Beta #2 906! :: EDD June 10th
    2015- 2 failed FET. We are done
    SURPRISE! BFP 8/8/16   EDD 4/1/17

     
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  • It depends on your situation and how many embryos you end up with. It usually ends up being a game-day decision you make with your RE.
    **Warning: Losses and living child mentioned**
    BFP#1 1/31/12, EDD 10/6/12 Harrison Gray born sleeping @ 18w6d. You changed our lives little guy.
    BFP#2 EDD 10/29/13, C/P 2/25/13, Bye little Ish, we barely got to know you.
    BFP#3 EDD 12/21/13, Baby Boots born 11/23/13 My rainbow baby!
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  • Mine prefers a 5DT if possible but it depends on the number of follicles I think.

    When I went to the IVF info night at my clinic, I seem to remember them saying that days 3-5 are when the sperm starts playing a role in embryo development so that is why eggs that are looking good on day 3 might arrest between 3-5 and is often a result of sperm issues.

    Basically their argument was, by day 5 you know that the sperm are good too because they have had a couple of days to develop the embryo.

    I wish I could find some research on that online in case I am totally remembering it wrong.

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    TTC #1 since Jan 2012
    IVF March/April 2013
  • imagenoelcallum:

    Mine prefers a 5DT if possible but it depends on the number of follicles I think.

    When I went to the IVF info night at my clinic, I seem to remember them saying that days 3-5 are when the sperm starts playing a role in embryo development so that is why eggs that are looking good on day 3 might arrest between 3-5 and is often a result of sperm issues.

    Basically their argument was, by day 5 you know that the sperm are good too because they have had a couple of days to develop the embryo.

    I wish I could find some research on that online in case I am totally remembering it wrong.

    This is what I was thinking too. My clinic does 3DT when egg quality is an issue or when there aren't many embies. They do 5DT for women who have MFI or a nice big selection of embies. They have an idea when you start IVF whether you'll be a 3 or 5 DT, they get more info at ER, and they make the decision the morning of day 3. I'll be getting a call tomorrow either telling me to come in ASAP or wait till Saturday.

  • I don't know if my RE has a preference. For our first IVF we did a 3dt because we only had 3 viable embryos on day 2 and then only 2 on the day of transfer. I guess his theory is to put them in their natural environment because they stand a better chance. For this IVF we had enough still viable on day 3 that they pushed us to a 5dt.
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  • If your clinic prefers doing 3DT, then I would go with that. That means they have more success growing embryos to day 3 rather than waiting till day 5. Just as it was already mentioned there are pros and cons to both. But you do not want to push for a 5DT if the lab is not comfortable with that. Don't worry, there is nothing wrong with a 3DT. If you were to ask on PAIF or SAIF you will see that both 3DTs and 5DTs can be successful! Try to trust your Dr, I know it's hard :) 
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  • I feel like I'm having a flashback :-)

    The only thing that helped me in this choice was to follow my heart. I had a 5dt planned for friday but it was my very last embie and I just didn't feel comfortable with that. I called them and had the ET done today (3dt). There are pros and cons for both of them and there is no scientific study revealing the ultimate truth. Just choose the path of least regret.

    Btw, thank you to all the ladies that gave me support when I was facing the same dilemma  <3

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  • We were told that we will be doing a 5DT, but we are MFI so that could be why.
    Married 8/14/10 * TTC since Aug 2010 * Met with RE in Feb 2012 * DH: low motility, low sperm count, elevated FSH * Me: Stage 4 Endometriosis * Laparotomy to remove endo in May 2012 * June 2012 - DH on Rx to hopefully increase count/quality * Re-tested sperm 10/22/12, count/quality have both dropped * IVF #1 w/ICSI * Transferred 2 beautiful embryos on 2/18/13 * Beta #1 3/1/13 - 636!!! Beta #2 3/3/13 - 1796!!! First ultrasound scheduled for 3/18/13 Image and video hosting by TinyPic birthday2012_small Anniversary
  • My RE wants to see how many eggs fertilize and the quality of the embies before deciding.  If we have just a few, she'll do a 3 dt.  If more, we can be more selective and let them grown a little while longer before transferring.  We are doing ICSI with IVF, so we have already been identified with mild MFI.
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  • Mine definitely prefers a 5dt. Both Ivfs, I have had 3 or 4 embies only and she pushed to 5dt each time.
    Me: 37, DH: 38: ttc 7 years, dx: unknown
    10/11: after 2 years, saw a RE, FSH 5.4
    11/11: BFP! (surprise after thyroid & normal hsg),
    12/11: missed m/c after 7 week u/s, 1/12: D&C
    6/12 IUI#1-IUI #3: clomid = BFP!, C/P
    IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
    IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
    IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
    IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
    10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
    Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
    Baby Will born 8/18. He's perfect.
  • I would ask how successful the lab is at growing to blast. A lot of human mistakes can happen after day 3. Also, if you have a lot of embies, growing to blast isn't as risky. Some REs believe embies that wouldn't make it to blast can turn into healthy pregnancies. With that being said, I had 15 perfect embies on day 3 with no fragmentation and only 4 made it to blast. I can't image if I would have frozen 11 bad embies that looked perfect.
    ~ Everyone Welcome ~
    TTC: 05/2011 Me: 32, All Clear DH: 38 Dx: MFI Low Testosterone & 1% Morphology
    IVF #1 w/ICSI & IMSI, 12/03/12: ER: 27R, 20M, 15F
    4 blasts frozen (3BA 4BA 4BB 5BB) b/c of moderate OHSS
    FET #1: 02/08/13 Transferred 3BA & 4BA | HPT 5dp5dt BFP!

    10dp5dt Beta #1 - 810 | 12dp5dt Beta #2 - 1843 BabyFetus Ticker
  • imagenoelcallum:

    Mine prefers a 5DT if possible but it depends on the number of follicles I think.

    When I went to the IVF info night at my clinic, I seem to remember them saying that days 3-5 are when the sperm starts playing a role in embryo development so that is why eggs that are looking good on day 3 might arrest between 3-5 and is often a result of sperm issues.

    Basically their argument was, by day 5 you know that the sperm are good too because they have had a couple of days to develop the embryo.

    I wish I could find some research on that online in case I am totally remembering it wrong.

    PP is right. Sperm is activated after day 3.

    ~ Everyone Welcome ~
    TTC: 05/2011 Me: 32, All Clear DH: 38 Dx: MFI Low Testosterone & 1% Morphology
    IVF #1 w/ICSI & IMSI, 12/03/12: ER: 27R, 20M, 15F
    4 blasts frozen (3BA 4BA 4BB 5BB) b/c of moderate OHSS
    FET #1: 02/08/13 Transferred 3BA & 4BA | HPT 5dp5dt BFP!

    10dp5dt Beta #1 - 810 | 12dp5dt Beta #2 - 1843 BabyFetus Ticker
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