Secondary IF

Anyone ever use Misoprostol ?

since my mc on December 1st my HCG levels were being monitored weekly and dropping. That was until Tuesday when it went back up from 45 to 202. Turns out it was residual tissue with growing cells. The RE gave me misoprostol to use this weekend. You insert 4 tablets vaginally and then there is cramping and bleeding to clear everything out. The first day I had bad cramping but nothing ever came out. Today same thing. Not sure what's going on but I'm beyond frustrated and just want this over with.
Dx PCOS Three cycle of Clomid- BFN HSG- clear 6/09-Follistim and HCG IUI on 7/7/09 BFN 7/09- Follistim and Ovidrel IUI on 8/11/09 BFP! beta #1-342 beta #2-717 Joey was born on 5/5/10 Trying for #2 since 6/12 6/12- Gonal F and Ovidel IUI on 7/10. BFN 8/12- Gonal F and Ovidrel. IUI on 8/10. BFN 9/12- Gonal F and Ovidrel IUI BFN 10/22 Gonal F, Menopur, Ganirelex 11/4 trigger 11/6 ER 14R 10F 11/11 ET transferred one 4AA embryo beta 11/20! BFP Betas stop multiplying . m/c at 5 weeks moving on to FET if my numbers ever get back to 0!

Re: Anyone ever use Misoprostol ?

  • I used it orally with my first loss, and it didn't work that great for me. I had some cramping but no big increase in bleeding like I thought I would. I just continued to bleed pretty moderately for a few days before I went back to the ob. She did an exam and was actually able to pull some tissue out that was stuck. After that, my bleeding did increase, but it was still never super heavy. My betas did go down pretty quickly after that though.

    I'm sorry you're going through this. I can understand wanting it over.
    TTC #1 since 6/08. Cycle #6 - BFP 12/22/08, EDD 9/3/09, DD 8/14/09 at 37w1d
    Baby Birthday Ticker Ticker
    TTC #2 since 6/11
    me=36 - low AMH, DH=38
    BFP #2 - 8/31/11, EDD 5/10/12, M/C 9/23/11
    BFP #3 - 3/4/12, EDD 11/14/12, CP 3/11/12
    BFP #4 - 5/9/12, EDD 1/19/13, CP 5/11/12
    BFP #5 - 8/22/12, EDD 5/5/13, CP 8/24/12
    IVF#1 - January 2013 - EPP/Antagonist - 7R, 3M, 2F, 3dt of 2 8-cell embies
    BFP #6 - 2/3/13, EDD 10/15/13, DS 9/18/13 at 36w1d
    Lilypie First Birthday tickers
  • Thanks so much for your response.
    Dx PCOS Three cycle of Clomid- BFN HSG- clear 6/09-Follistim and HCG IUI on 7/7/09 BFN 7/09- Follistim and Ovidrel IUI on 8/11/09 BFP! beta #1-342 beta #2-717 Joey was born on 5/5/10 Trying for #2 since 6/12 6/12- Gonal F and Ovidel IUI on 7/10. BFN 8/12- Gonal F and Ovidrel. IUI on 8/10. BFN 9/12- Gonal F and Ovidrel IUI BFN 10/22 Gonal F, Menopur, Ganirelex 11/4 trigger 11/6 ER 14R 10F 11/11 ET transferred one 4AA embryo beta 11/20! BFP Betas stop multiplying . m/c at 5 weeks moving on to FET if my numbers ever get back to 0!
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  • I'm so so sorry!  I don't have any personal experience but one of my best friends used it twice, back to back, after her loss and it never worked so she ended up needing a DNC. I really hope that's not the case for you and this is all over for you soon so you can move on. ((HUGS))
    imageimage

    First Time: DD born 3/2011 after trying for two years, LAP, and two IUIs w/ Femera + Ovidrel
    This Time: 4/12 Femera IUI #1 BFN, 5/12 Femera + TI BFN, 6/12 Femera + IUI #2 BFN, 7/12 Femera + IUI #3 BFN, 8/12 Follistim IUI #4 BFN
    IVF #1: ER 11/5/12 : 17 eggs retrieved/6 fertilized, ET 11/10/12 : 5dt of 2 embies/0 frosties BFN
    IVF #2: ER 1/28/13 : 12 eggs retrieved/9 fertilized, ET 2/2/13 : 5dt of 2 embies/0 frosties BFN
    IVF #3: ER 4/15/13 : 13 eggs retrieved/7 fertilized, ET 4/18/13 : 3dt of 3 embies/0 frosties BFN
    Laparoscopy 5/24/13 : Stage 2 Endo, Scaring, and Both tubes Blocked but successfully Opened
    IVF #4 (Clinical Trial): ER 7/22/13 : 15 eggs/8 fertilized, ET 7/25/13 : 3dt of 3 embies/0 frosties BFN
    IVF #5: ER 11/4/13 : 13 eggs/12 fertilized, ET 11/9/13 : 5dt of 2 embies/0 frosties BFP!!! Beta 11/20/13 = 447 1 Beautiful Baby! EDD: July 28, 2014
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