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Taking Clomid CD3-7 or CD5-9?

tlalli7106tlalli7106 member
in Trouble TTC
Is there a reason why some doctors will tell you to take it between CD3-7 and then some tell you to take it CD5-9? Are there any benefits to taking it a different set of cycle days? My first cycle on Clomid my RE had me on it CD3-7 and I responded very well...lots of nice and mature follicles. Now that I am seeing an RE here in Japan he has only ever told me to take it CD5-9 which it seems as if I am not responding to it at all, only ever one mature follicle (except last cycle there was a second one but size was....eh, just okay) Any thoughts?
TTC our first Navy baby! Me:27 DH:30, together since 8/2003, Married on 7/2006
9/26/10 stopped BCP and started TTC.
9/2011 referred to RE. All blood work normal and DH's SA=normal results
11/2011 HSG=both tubes clear
One natural (monitored) cycle of Clomid, 50mg 2/2012= BFN
Getting ready for first IUI, 3/2012 received orders to Japan! (postponed IUI)
5/2012 Moved to Japan, fought Tricare for months over referral (no fertility treatment on our military base) for Japanese RE out in town!
8/2012 Started seeing new RE
9/2012, post coital test= hostile cervical fluid, (finally) moving on with first IUI!
9/29/2012 IUI #1+trigger= BFN
10/27/2012 IUI #2+100mg Clomid CD5-9+trigger= BFN
11/28/2012 IUI #3+100mg Clomid CD5-9+trigger= BFN
12/28/2012 IUI#4+100mg Clomid CD5-9+trigger=BFN
2/1/2013 IUI#5+injectables+trigger=BFN
3/2013 IUI#6+injectables+trigger=???
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Re: Taking Clomid CD3-7 or CD5-9?

  • honeygirl500honeygirl500
    Some people say 3-7 is for quantity and 5-9 for quality.  I have done both, as well as 4-8.  I think it is mostly just dr pref.  One mature follicle is actually good on Clomid. You really don't want lots of mature follicles, you might end up with HOM.  My RE doesn't really like over 3, so 1 is just fine. 
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    TTC since April 2010
    Diagnosed w/PCOS as a teen
    Aug 2011 dx MFI
    Oct 2011 referral to RE 1500mg Met
    5 Rounds of Clomid
    On waiting list for injects/IUI
    P/SAIF Welcome
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  • curlylocks3curlylocks3 member
    I'll be taking it 37. I ovulate on my own on cd11 or 12 and by day 3 my body is starting to gear up on its own so my doctor said starting on day 5 isn't an option for me.
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    О Привязать! Z!
    The Science Babies debuted 5/6/14 @ 34 weeks
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  • Shortie24Shortie24 member
    All 5 medicated cycless (Clomid-4, Femara-1) I was instructed to take it on CD5-9. At my last appt, I discussed changing it to CD3-7 since I'm a very slow responder and this would give me an "extra" two days on it.

    photo 46122502-649c-4d9b-a99e-dc22cf009d51_zpsf72c5124.jpg photo mason4_zps7f19f81c.jpg

    Baby Birthday Ticker Ticker TTC 07/2010, Dx with PCOS 11/2011, H's S/A= Perfect!!! HSG= both tubes clear!
    Round #6- 7.5mg Femara+ .5mg Dex+ 75iu Gonal-F+ hCG trigger+ IUI=BFP!!!
    Beta #1(14dpo)- 94 Beta#2(22dpo)- 1,619 Beta#3 (28dpo)- 11,396!!!

    Just a Little Blog

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  • Svenny1011Svenny1011 member
    My understanding was the quality vs quantity thing too. CD 3-7, for example, may produce more eggs to be fertilized, and CD5-9 would give you maybe one larger, more mature egg.  
    Married since 2008 | TTC #1 since 2011

    2 losses: Nov '11 and Aug '12
    Dx: Feb '13 - HSG shows clear tubes but minor diverticulitis; Borderline DOR; Low DHEA and low testosterone.
    Moving on to IUI or IVF.

    3.4.13:  Holy crap! Surprise natural BFP on cycle #19. EDD 11.12.13
    We've got a peen.....it's a boy! 
    Little man born 11.17.2013 via c-section


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  • katekat8721katekat8721 member

    imagecurlylocks3:
    I'll be taking it 37. I ovulate on my own on cd11 or 12 and by day 3 my body is starting to gear up on its own so my doctor said starting on day 5 isn't an option for me.

    Same here


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  • Aurora1181Aurora1181 member

    imagehoneygirl500:
    Some people say 3-7 is for quantity and 5-9 for quality.  I have done both, as well as 4-8.  I think it is mostly just dr pref.  One mature follicle is actually good on Clomid. You really don't want lots of mature follicles, you might end up with HOM.  My RE doesn't really like over 3, so 1 is just fine. 

     

    I've heard this same thing. My RE said that clomid and letrozole/femara are, for the most part, there for "monofollicular" ovulation- one follicle is a good response, they say. But I I know I was always disappointed in only having one.

    ---------------Siggy Warning--------------------


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    Me: 32, DH: 34  / TTC since February 2011 / SA: all normal, HSG: all clear! / on Lovenox for anticardiolipid antibodies
    4 IUIs with Clomid, Letrozole, and Menopur. All BFN.
    9/12: lap / hysteroscopy: found and removed mild endometriosis, cervical polyp, and 2 para-tubular cysts
    5/13 IVF #1: Follistim, Menopur, Ganirelix, 10R/4M/4F, ET of 2, 5 cell and 4 cell, no frosties = BFN
    12/13 IVF #2 = November / December 2013. Microdose Lupron Protocol: 15R/6M/6F, Froze all 6 due to high E2 and P4
    FET 1: Jan 22, 2014 of one 4AB blast and one 3BB blast (3 blasts on ice!)
    BFP on HPT 4dp5dt, Beta #1 9dp5dt: 310, Beta #2 11dp5dt: 899
    First u/s on 2/17/14: TWINS!!!!! both w/HBs of 114 at 6w3d, HBs 150 and 152 at 7w5d
    5/27/2014: Team purple!!!!  EDD 10/10/2014 / 
    Delivered by c-section at 32w0d 8/15/2014 due to preeclampsia/HELLP syndrome
    Baby Boy 4lbs 1oz, 17 inches
    Baby Girl 3lbs 5oz, 16 inches

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  • conradtnconradtn member
    I took clomid on CD 3-7 for quantity. 
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Married Sept 2008
    ~~TTC Nov 2010~~
    IUI #2: 1/21/13-100mg Clomid(CD3-7)(8M post wash) + progesterone= BFP!! EDD 10/13/13
    Beta #1=81.1 Beta #2=134.5 Beta #3=58.1 #4=2369 WTH?!-Not sure if its viable
    2/21/13 - Went to RE expecting the worse and saw the flutter of the heart.To God be the Glory!!
          5/29 - It's a Girl!!
    8/21/13 - Naomi born at 32w3d by csection due to Pre-E
    ~~PAIF/SAIF Welcome~~ 
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    imagephoto A789AD50-EAFE-4955-A617-02358EF02DBE_zpsbxkk1n87.jpg
    My Wonder Woman!

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  • smilormariesmilormarie member

    I'm a 4-8 girl.  This is my first cycle with clomid so I don't know how I'll respond yet but on my own without meds I was ovulating between days 16-19.    Good luck!

    My CD14 monitoring appt showed 2 follicles.  My doctor said the CD4-8 protocol is following exactly as planned.  He wanted to aim to have me ovulate on Day 16 which it looks like we will, and he wanted more targets for hubby's sperm (I usually ovulated on my own without Clomid so I'm getting 1 extra try this month, so the speak).

    ??
    Our little lightbulb is on the way!
    image
    12 weeks 3 days


    TTC since Oct 2011
    Me: 33, hypothyroidism since 14, cleared all HSG, US, Pre-pregnancy panel tests.
    Hubby: 36, testicular Ca, chemo April-May 2012.
    Natural cycle IUI #1 with trigger and Progesterone Suppositories (Jun 2012) Neg
    Natural Cycle IUI #2 with trigger and Progesterone Suppositories (Jul 2012) NEG
    Aug 2012 - break due to needing a girls' weekend in Cape Cod
    Natural Cycle IUI #3 with trigger and prednisone (Sep 2012) NEGATIVE
    Switched fertility clinics - forced break Oct 2012
    Natural Cycle IUI #4 (Nov 2012) no trigger, no progesterone, no prednisone (Nov 2012) - Neg
    1st round Clomid Cycle IUI #5 (Dec 2012) - POS
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