Infertility

3DT vs. 5DT

How is it determined if you will have a 3DT or a 5DT.  Are there pros/cons with each?  TIA!
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Lilypie First Birthday tickers

TTC #1 since February 2011
Me: 29 (3/5/13- high NK cells)  DH: 28 (5/8/12- MFI low morph and motility)
Cycle #21 (IUI#1), Cycle #22 (HSG 9/21/12) and Cycle #23 (IUI#2)=  image
Cycle #24- December Snow Bunny IVF #1
ER 12/6/12 (14R, 11M, 9F), ET 12/9/12 transferred 2 day 3 embies
Bleeding and low betas=very cautious image C/P 5W3D
Cycle #26 March Lucky Duck- FET #1
scheduled 3/20/13- CANCELLED- lining issues
Cycle #27 May Emerald- FET #1.2
delayed- Starting Trental for 3 months + natural cycles Cycle #28-30=  image
Cycle #31 August Shooting Star- FET #1.3 
transferred 1 hatching blast 8/21/13= imageBetas 8/30 (108) and 9/3 (565)

U/S 9/19/13- HR is 128!  U/S #2 10/4/13- HR is 174!
It's a BOY!

Re: 3DT vs. 5DT

  • i asked this question at my IVF orientation class, b/c i thought that the 5 day was better, but my doctors explained it as.....if by day 3 there is a stand out stellar egg, they will transfer it, but if they all seem to be moving along at the same pace, they will wait until day 5 to see who stands out then. They compared it to running a race, everyone starts out at the same place, but as time goes bye, there is going to be people that stand out over the others. HTH!

     

    ********Pregnancy Mentioned*******

    Me 33 DH 33 Together since 2002 TTC since Oct 2010 RE March 2012 HSG left tube blocked with fluid July Lap done, removed left tube and right tube damaged Break until we can fund IVF Mock Transfer and Consent Signing appt 11/2 Started BC 12/11, Injection class 12/18 Lupron starts 12/27, Menopur,Lupron and GonalF start 1/9, Triggered 1/20, ER 1/22 11R, 3 made it to day 5, ET 1/27 of 2 blasts, I frozen 2/7 beta #1 380, 2/11 beta #2 ? DD born 10/18/2013 

    FET 9/2015-BFN no embryos left........trying on own until I discovered my only tube was blocked
    IVF#2- started stims 6/12 ER 6/22 16 ER 11 mature 8 fertilized ET 6/27 2 day 5 embryos AB and BB put in. 1 frozen BC. Beta #1-175 Beta #2- 422.  Beta #3- 1,024. US-7/29
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    I've never heard that explanation, and while it is a valid one, the more common explanation tends to be related to the number and quality of embryos at day 2 or 3.  I would say if you only have, say 4 or less good ones, you'll probably get recommended for 3 days, because it's possible some or all might not progress enough to make it to 5 days.  If you have a lot more, then they can wait until 5 days to see which ones are looking the best. 

    In my case, I had 10 and 16 fertilize respectively during my IVFs.  By day 3, I had 5 and 8 good ones left, so i made it to 5dt both times.  I know one of my fellow 2IFers, who just had her ET on Monday, had a 3dt because she had 4 embies left.

    You can always push for a 5dt if you want to know how they will turn out, but if you have few to work with, the overriding consensus is that the embies will have a better chance to progress inside of you, and might make it, whereas they might arrest in the culture if left until 5 days.

     

    10/10: Married; 5/11: Dx: Blocked Fallopian Tube; 7/11: D&C/Hysteroscopy to remove polyp
    IVF #1: 9/11: ER: 12R, 11M, 10F, No Frosties; 5dt: 2 blasts, 1 morula; DD born 6/3/12
    IVF #2: 11/12-12/12: ER: 20R, 20M, 16F, 4 Frosties; 5dt: 3 blasts, DS born 8/9/13
    Baby Birthday Ticker Ticker  Baby Birthday Ticker Ticker
  • My clinic takes the embryos to day 5 if you make the criteria: 5 embryos at 4 cells or more at day 2.

    <Image and video hosting by TinyPic
    Married June 2011 Dx: anovulatory due to prolactinoma (1.5cmx 1.5cm in 2006)
    April 2012: MRI- questionable cyst 8mg by 12mm in pituitary ; referred to RE by Ob-gyn after amenorrhea x 4+ months, provera ineffective, low estrogen level
    cycle 1: May 2012, clomid 50mg; cycle cancelled, thin lining, no response
    cycle 2: June 2012, femara 5mg; cycle cancelled, no response
    cycle 3: July 2012, femara 7.5mg; cycle cancelled (largest folli on Cd12 & cd 16: 11, lining 4)
    Repeat MRI July 25,2012- Cyst unchanged, likely old infarction.
    Aug. 8: met with RE, move to injectables if HSG and SA normal
    Aug. 23: HSG all clear; DH- perfect
    Switched to a new RE in early Sept. IVF here we come
    Genetic testing reveals: Fragile X- Intermediate risk/grey zone.
    IVF#1: ER 11/30: 14 retrieved, 10 mature, 7 fertilized. E2 prior to trigger 5200. Decision made to freeze 6 embryos and transfer later due to OHSS.
    IVF#1.2/FET #1: estrogen injects start 1/18, FET delayed to try to thicken lining. lining 5.4mm. FET- 2/18- transferred one 3AA expanded blast. BFP 5dp5dt. Beta #1- 2/27 9dp5dt- 102.27 beta #2 3/1: 147 :(, beta #3 3/4: 268 told to stop meds and let nature take its course. requested 4th beta (3/6); Beta hell for 2 months.

    FET # 2: endometrial scratch 5/6, added estrace vaginally and ASA to delestrogen and PIO. June 10- transferred one 4AA hatched embryo, BFP 4dp6dt, Beta 1 (9dp6dt) 187, Beta 2 (11dp6dt): 412; Beta 3 (15dp6dt ): 4452. U/S #1- one beautiful embryo with a heartbeat of 133 at 7 weeks.  8 weeks: heartbeat 156. EDD 2/26/2014: born 2-3-14 induced due to Pre-E and HELLP at 36w5d.

    12/1: met with RE to discuss trying for #2


  • Thanks ladies for your feedback.  Does anyone know on what day they determine if any that are lucky enough to remain will be good enough to freeze?  What day does freezing occur?
    My Blog
    Lilypie First Birthday tickers

    TTC #1 since February 2011
    Me: 29 (3/5/13- high NK cells)  DH: 28 (5/8/12- MFI low morph and motility)
    Cycle #21 (IUI#1), Cycle #22 (HSG 9/21/12) and Cycle #23 (IUI#2)=  image
    Cycle #24- December Snow Bunny IVF #1
    ER 12/6/12 (14R, 11M, 9F), ET 12/9/12 transferred 2 day 3 embies
    Bleeding and low betas=very cautious image C/P 5W3D
    Cycle #26 March Lucky Duck- FET #1
    scheduled 3/20/13- CANCELLED- lining issues
    Cycle #27 May Emerald- FET #1.2
    delayed- Starting Trental for 3 months + natural cycles Cycle #28-30=  image
    Cycle #31 August Shooting Star- FET #1.3 
    transferred 1 hatching blast 8/21/13= imageBetas 8/30 (108) and 9/3 (565)

    U/S 9/19/13- HR is 128!  U/S #2 10/4/13- HR is 174!
    It's a BOY!

  • I only had 4 embies but my dr pushed for a 5dt. Even with just 4, she wanted to know which 2 were the best. I'm glad we waited as only 1 made it to blast. If we wouldn't have waited, it's a possibility we could have transferred the ones that didn't make it to day 5 well. Many studies are done on this, but I haven't found any real clear results. Just dependent on the feelings of the embryologist and the RE.
    Me: 37, DH: 38: ttc 7 years, dx: unknown
    10/11: after 2 years, saw a RE, FSH 5.4
    11/11: BFP! (surprise after thyroid & normal hsg),
    12/11: missed m/c after 7 week u/s, 1/12: D&C
    6/12 IUI#1-IUI #3: clomid = BFP!, C/P
    IVF #1(10/12) FSH 5.4, AFC: 16 long Lupron, 5R/5M/4F, all 4 made it to 5dt, 1 blast/1-8 cell transferred=BFN
    IVF #2(12/12)AFC 21, MD lupron, 4R/4M/3F, 5dt of 1 blast and 2-8cell. BFN.
    IVF#3(4/13) Natural start antagon protocol, 12R,11F. one PGS normal at day 6 transfer. BFN.
    IVF#4 (11/13) C.CRM (ODW.U normal 8/13 Still no Diagnosis) EPP/antagonist. ER 13R/7M/6F. Only 1 made it to freeze. Abnormal. Looking into options of DE, Fresh vs frozen.
    10/14 new local RE to look into what's next. CD3 FSH 4.7, AMH 0.9. Met with DE agencies and exploring options for feb/march 2015.
    Surprise natural bfp (4 days before donor is signed). Beta #1 at 9dpo: 51.8, 2nd beta: 195 (25 hours doubling) @11dpo. 3rd beta (12/15): 516 (35 hrs doubling) 4th beta(12/17): 895 (58 hours doubling) 5th beta(12/19): 2120. U/S at 5w0d(12/22): one gestational sac with yolk sac. U/S #2 (6w0d)12/29. One little bean measuring 6w0d with HR 124. 3rd u/s(1/4)7w0d: baby measuring 7w2d. HR 134. 3/30: A/S at MFM went great except for low lying placenta. Verifi results are normal! Team Blue! Please send any positive thoughts our way! EDD:8/24/2015
    Baby Will born 8/18. He's perfect.
  • imagejschwind22:
    Thanks ladies for your feedback.  Does anyone know on what day they determine if any that are lucky enough to remain will be good enough to freeze?  What day does freezing occur?

    They make that call at day 5 or 6.  After day 6, the embies can't survive outside the body.  I had my 5dt yesterday, so I'm waiting to hear if any made it to freeze.  The RE thought one should, and 1-2 more might, but since I didn't get any last time, I'm not counting on anything.

    10/10: Married; 5/11: Dx: Blocked Fallopian Tube; 7/11: D&C/Hysteroscopy to remove polyp
    IVF #1: 9/11: ER: 12R, 11M, 10F, No Frosties; 5dt: 2 blasts, 1 morula; DD born 6/3/12
    IVF #2: 11/12-12/12: ER: 20R, 20M, 16F, 4 Frosties; 5dt: 3 blasts, DS born 8/9/13
    Baby Birthday Ticker Ticker  Baby Birthday Ticker Ticker
  • ::TICKER WARNING::

     

    My clinic only did 6dts.  My RE's reasoning was that the sperm doesn't really start "doing it's thing" until around day 4/5, so pushing off to day 6 you get a much clearer picture of how things are looking.  Of course, he said it much better. 

    We had 8 eggs fertilize, on ET day when we got there we had 5 that looked really good or better.  We put 2 in and froze 3. 

    Warning No formatter is installed for the format bbhtml
  • Yep, pp explained it perfectly! At the end of the day, it's really up to the egg...we can all plan for a 5dt...but if none make it...well!

    ~TTC#1 Since July 2011~ 
    Dx: Fibroids & Tubal Infertility
                                                        9/12 -IVF#1 =BFN; 5/14 -IVF#2=BFP:-) EDD 2.19.2015                                                

    S/PAIF Welcome 





    imageimageimage

    BabyFetus Ticker

  • I like this page for reference https://www.advancedfertility.com/blastocy.htm

     With our last IVF, we retrieved 8, 5 of which were able to fertilize normally.  They brought us in for a 3dt & we transferred the best 2.  They watched the remaining 3 until day 6 & were unable to freeze them due to the poor quality.  

    "Everything will be alright in the end. So if it's not alright, it is not yet the end."
    Me:29 DH:29  TTC since 1/11 Dx: unexplained IF/early DOR/immune issues 
    Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN
    8/30IVF#1 Antagonist protocol- ER 9/11-8R, 7M, 5F. 
    ET 9/14 2 embies transferred. 1 10cell Grade 4, 1 8cell Grade 4. No frosties. BFN
    IVF#2 Antagonist protocol plus baby aspirin- ER 12/5-16R, 12M, 8F!
    ET 12/10 5dt! 1 fully expanded blast & 1 early blast. No frosties. BFN
    3/13 hysteroscopy & polypectomy, Consulted w Dr. Kwak-Kim.  
    DX: High NK cells, cytokines, DHEAs& PAI1;  hypothyroid, +APA, restricted bloodflow
    7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle
    (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim)
    ER 7/19 14R, 11M, 9F(4 natural fert, 5 with ICSI)
    ET 5dt 7/24 2 fully expanded blasts.  SURPRISE 3 FROSTIES!!!
    Beta #1 8/2 335!!!! Beta #2 829!!!  1st u/s 8/14 showed TWINS!!!!!
    11/11: TEAM PURPLE!!!!!
    3/21/14-L&W born at 37w via csection

    Here Comes the Sun Blog
    PAIF/SAIF welcome!
  • My clinic only does 5dt.  But I'm doing Natural Cycle IVF so I only will have 1 egg but they like to watch it to day 5.
    image
  • I got called yesterday which is day 5 that 3 of 7 made criteria to be frozen (blastocysts As or Bs) and that they will watch the other 4 one more day but they likely won't make it.  Received the call today that 3 more were frozen (2 are approaching hatching and 1 blastocyst)!!!  I had prepared myself for none but this was such great news so now we have 6 on ice :)

    <Image and video hosting by TinyPic
    Married June 2011 Dx: anovulatory due to prolactinoma (1.5cmx 1.5cm in 2006)
    April 2012: MRI- questionable cyst 8mg by 12mm in pituitary ; referred to RE by Ob-gyn after amenorrhea x 4+ months, provera ineffective, low estrogen level
    cycle 1: May 2012, clomid 50mg; cycle cancelled, thin lining, no response
    cycle 2: June 2012, femara 5mg; cycle cancelled, no response
    cycle 3: July 2012, femara 7.5mg; cycle cancelled (largest folli on Cd12 & cd 16: 11, lining 4)
    Repeat MRI July 25,2012- Cyst unchanged, likely old infarction.
    Aug. 8: met with RE, move to injectables if HSG and SA normal
    Aug. 23: HSG all clear; DH- perfect
    Switched to a new RE in early Sept. IVF here we come
    Genetic testing reveals: Fragile X- Intermediate risk/grey zone.
    IVF#1: ER 11/30: 14 retrieved, 10 mature, 7 fertilized. E2 prior to trigger 5200. Decision made to freeze 6 embryos and transfer later due to OHSS.
    IVF#1.2/FET #1: estrogen injects start 1/18, FET delayed to try to thicken lining. lining 5.4mm. FET- 2/18- transferred one 3AA expanded blast. BFP 5dp5dt. Beta #1- 2/27 9dp5dt- 102.27 beta #2 3/1: 147 :(, beta #3 3/4: 268 told to stop meds and let nature take its course. requested 4th beta (3/6); Beta hell for 2 months.

    FET # 2: endometrial scratch 5/6, added estrace vaginally and ASA to delestrogen and PIO. June 10- transferred one 4AA hatched embryo, BFP 4dp6dt, Beta 1 (9dp6dt) 187, Beta 2 (11dp6dt): 412; Beta 3 (15dp6dt ): 4452. U/S #1- one beautiful embryo with a heartbeat of 133 at 7 weeks.  8 weeks: heartbeat 156. EDD 2/26/2014: born 2-3-14 induced due to Pre-E and HELLP at 36w5d.

    12/1: met with RE to discuss trying for #2


  • imageBrideJackie11:

    I got called yesterday which is day 5 that 3 of 7 made criteria to be frozen (blastocysts As or Bs) and that they will watch the other 4 one more day but they likely won't make it.  Received the call today that 3 more were frozen (2 are approaching hatching and 1 blastocyst)!!!  I had prepared myself for none but this was such great news so now we have 6 on ice :)

    Wow!  Congrats!

    My Blog
    Lilypie First Birthday tickers

    TTC #1 since February 2011
    Me: 29 (3/5/13- high NK cells)  DH: 28 (5/8/12- MFI low morph and motility)
    Cycle #21 (IUI#1), Cycle #22 (HSG 9/21/12) and Cycle #23 (IUI#2)=  image
    Cycle #24- December Snow Bunny IVF #1
    ER 12/6/12 (14R, 11M, 9F), ET 12/9/12 transferred 2 day 3 embies
    Bleeding and low betas=very cautious image C/P 5W3D
    Cycle #26 March Lucky Duck- FET #1
    scheduled 3/20/13- CANCELLED- lining issues
    Cycle #27 May Emerald- FET #1.2
    delayed- Starting Trental for 3 months + natural cycles Cycle #28-30=  image
    Cycle #31 August Shooting Star- FET #1.3 
    transferred 1 hatching blast 8/21/13= imageBetas 8/30 (108) and 9/3 (565)

    U/S 9/19/13- HR is 128!  U/S #2 10/4/13- HR is 174!
    It's a BOY!

  • imageBrideJackie11:

    I got called yesterday which is day 5 that 3 of 7 made criteria to be frozen (blastocysts As or Bs) and that they will watch the other 4 one more day but they likely won't make it.  Received the call today that 3 more were frozen (2 are approaching hatching and 1 blastocyst)!!!  I had prepared myself for none but this was such great news so now we have 6 on ice :)

    Wow!  Congrats!

    My Blog
    Lilypie First Birthday tickers

    TTC #1 since February 2011
    Me: 29 (3/5/13- high NK cells)  DH: 28 (5/8/12- MFI low morph and motility)
    Cycle #21 (IUI#1), Cycle #22 (HSG 9/21/12) and Cycle #23 (IUI#2)=  image
    Cycle #24- December Snow Bunny IVF #1
    ER 12/6/12 (14R, 11M, 9F), ET 12/9/12 transferred 2 day 3 embies
    Bleeding and low betas=very cautious image C/P 5W3D
    Cycle #26 March Lucky Duck- FET #1
    scheduled 3/20/13- CANCELLED- lining issues
    Cycle #27 May Emerald- FET #1.2
    delayed- Starting Trental for 3 months + natural cycles Cycle #28-30=  image
    Cycle #31 August Shooting Star- FET #1.3 
    transferred 1 hatching blast 8/21/13= imageBetas 8/30 (108) and 9/3 (565)

    U/S 9/19/13- HR is 128!  U/S #2 10/4/13- HR is 174!
    It's a BOY!

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