Secondary IF

embryo transfer today (low amh)

Hi,

 I went in for my first embryo transfer this morning.  I turn 32 tomorrow and have an amh .50...My RE was really surprised that out of my 4 that fertilized I had two grade 1aa "perfect" hatching blasts ready to transfer.  I also had a morula too (that had fertilized late) that they will keep growing and hopefully be able to freeze tomorrow.  I am trying to remain positive but it is hard not to start the "what iffing"  The main reason I am worried is that last ivf I did pgd - 7 embryos were biopsied and only 2 were genetically normal.  The 2 normals however were also of the worst quality. Last cycle I did not have any day 5 hatching blasts of the best quality though, so I am hoping these have a much better shot at being normal.  I almost did the pgd again on them before the transfer but my RE recommended against it so we just went for it. Do you guys think that at least one of these is going to stick?  I am praying so hard for this.  This has definitely been one of the most stressful experiences ive ever had!  My doctor says my ovaries are not predictable that I could have one cycle with all healthy embyros and the next with all abnormals.  He compares me to a 45 year old.  It is just so shocking to hear!   

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Re: embryo transfer today (low amh)

  • GL...  Sending vibes your way!
    DS#1 born 9/23/06 
    Twins DS#2 and 3 born at 31 weeks, 3 days due to a short cervix on 8/2/13.
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  • Thank you! Means a lot!
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  • I'll be sending T&P this is your cycle!
    Lilypie Third Birthday tickers Lilypie Pregnancy tickers Dx: Hypothalamic Amennorhea (Unexplained) DS #1: IVF #1 - Born: 3/15/10 TTC #2: FET Cycle #1: BFP 11/4/12(HPT) - Beta #1: 61.8 Beta #2: 60 :( Beta #3: 14 Natural M/C FET Cycle #2: ET: 2/13/13, BFP 2/20/13 (HPT) - Beta #1:9dp5dt(2/22/13) - 93.1 - Beta #2:12dp5dt - 543
  • Praying this works for you!!!  Think positive!!!  Good luck!!!
    H: 34 dx Azoospermia due to CBAVD from CF  
    ME: 39 IS FINE!!!  DOR and poor AMH/FSH/LH
    IVF/ICSI/PESA #1 Beta 1 373 Beta 2 1783 BOY/GIRL TWINS!! Born April 2010!!
    Natural FET 5/26/12 2 blasts Beta 1 207 Beta 2 513 Beta 3 1377 U/S 6/28 Pregnancy not viable d & c scheduled :( 
    IVF/ICSI/PESA #2 ER 11/15/12 Nothing to transfer :( 
    IVF/ICSI #3 April 2013 MDLF 3dt of 3 embryos, chemical :(  
    IVF #4/ICSI/MESA/CCS/FET EPP April 2015
    ODWU CCRM with Dr. Sch COMPLETE!!!! Put on acai supplement they are studying for DOR and embryo quality.
    DAY 3 Labs Drawn 2/26 put on vitamin D and calcium supplements
    Regroup and Protocol Reveal 3/04 "Bazooka Protocol" EPP with MDLF "Protocol 6 with patches"
    ER/MESA 4/10 ER 9 eggs retrieved MESA success found live swimmers :)
    Fertilization Report 6 eggs mature and ICSI'd 4 eggs fertilized normally
    Day 6 Report to Blast for CCS 4/16: 2 DAY 5 BLASTS BIOPSIED FOR CCS a 4AB and a 3AB!!!!
    CCS Results BOTH BLASTS CCS NORMAL!!!!!!  call on 4/24
    Regroup call to discuss CCS results and FET call on 5/20
    FET prep: CD 1 6/08 CD 3 Start BCP 6/10, HSG 6/12 Lupron Start 10 iu 6/17 End BCP 6/21 CD 1 6/23!!!
    Start vivelle patches 6/25 change e/o/d reduce Lupron to 5iu 6/25 Blood Draw 7/01, 7/08, 7/15, 7/19
    Increase vivelle patches 7/03 2 change e/o/d and 7/05 change e/o/d 3 and 7/07 4 change e/o/d add vaginal estrace 2x a day
    Lining Check/Blood Draw 7/08 and 7/15 End Lupron 7/18  Start PIO 1ml daily 7/18  Blood  Draw 7/19
    Flight to clinic 7/22
    FET 2 CCS BLASTS :):)  7/23 :):) YES YES both thawed and both fully expanded :):)
    7/26 :):) 3dp5dt PM very very faint positive FRER
    7/27: 4dp5dt Neg Digi AM but very very faint positive FRER PM POSITIVE DIGI CLEARBLUE PREGNANT 1-2 :):) 
    7/31:8dp5dt AM POSITIVE DIGI CLEARBLUE PREGNANT 2-3!!!! :):) 
    Beta 1 8/01= 408!!!!!!!!!! at 9dp5dt FET
    Beta 2 8/03 = 1014!!!!!!!!!! at 11dp5dt FET
    8/05/2015 AM POSITIVE DIGI CLEARBLUE PREGNANT 3+!!!! :):) 
    First Ultrasound: 8/20!!!!!! TWINS!!!!!!!!!!!!!!!!!  Genetics says BOTH BOYS!!!!!!!!!
    Second Ultrasound: 9/03!!!!!!!!!!










     










  • Good luck! Praying this is your cycle! I know it's hard but try and remember it only takes one and every cycle is different. Hang in there. 
    imageimage

    First Time: DD born 3/2011 after trying for two years, LAP, and two IUIs w/ Femera + Ovidrel
    This Time: 4/12 Femera IUI #1 BFN, 5/12 Femera + TI BFN, 6/12 Femera + IUI #2 BFN, 7/12 Femera + IUI #3 BFN, 8/12 Follistim IUI #4 BFN
    IVF #1: ER 11/5/12 : 17 eggs retrieved/6 fertilized, ET 11/10/12 : 5dt of 2 embies/0 frosties BFN
    IVF #2: ER 1/28/13 : 12 eggs retrieved/9 fertilized, ET 2/2/13 : 5dt of 2 embies/0 frosties BFN
    IVF #3: ER 4/15/13 : 13 eggs retrieved/7 fertilized, ET 4/18/13 : 3dt of 3 embies/0 frosties BFN
    Laparoscopy 5/24/13 : Stage 2 Endo, Scaring, and Both tubes Blocked but successfully Opened
    IVF #4 (Clinical Trial): ER 7/22/13 : 15 eggs/8 fertilized, ET 7/25/13 : 3dt of 3 embies/0 frosties BFN
    IVF #5: ER 11/4/13 : 13 eggs/12 fertilized, ET 11/9/13 : 5dt of 2 embies/0 frosties BFP!!! Beta 11/20/13 = 447 1 Beautiful Baby! EDD: July 28, 2014
  • wow that is a lot to absorb from your RE.  GL!  Hoping they snuggle in and you get your BFP!
    TTC#1: 14 months on our own (did HSG, b/w, SA);
    BFP on Cycle 14--TWINS! Identical twin boys stillborn at 19wks(1/9/10)
    3 break cycles; took clomid 50mg, BFP #2 Beta #1 35, Beta #2 338!!! Owen was born 2/11/11! 
    TTC#2: 4 cycles on clomid: BFNs
    BFP #3: Cycle #5 100mg clomid; beta #1 21; beta #2 6=CP 
    Cycle #6 break cycle TTC no meds=BFN
    Cycle #7: 150 clomid+ovidril+IUI=BFN (switched to RE)
    Cycle #8: follistem+ovidril+TI=BFN
    Cycle #9 Forced break due to cyst
    Cycle #10 follistem+ovidril+TI=BFN
    Cycle #11 follistem+ovidril+TI=BFN
    Cycle#12 Forced break due to cyst, went on BCP; did repeat HSG, Saline U/S
    Cycle #13 IVF: Follistim/Menapur ER 11-30 11 eggs, 5 mature, 4 fertilized and 3dt on 12-3; BFN
    Cycle #14: IVF#2 lupron/follistim/menopur ER 1-22, 19 eggs, 14 fertilized, 5dt on 1-27, BFP!! beta 1: 63, beta 2: 119; EDD 10-15-13; 1 frozen embie
    Miracle Surprise BFP, EDD 10-1-15; saw HB great Betas, 11weeks lost baby MC at home
    Moved forward with FET transfered solo frostie on 6-4-15, beta 1: 315, beta 2: 738, u/s showed one baby on track EDD 2-21-16
  • I share your concerns about PGS.  We did it with IVF 1 and 2 (round 2 we had 0 normals out of 4, so nothing to transfer).  So, I definitely know where you are coming from.  This time, I don't think we're going to do it though.  I am afraid that the PGS science may not be completely ready for prime time use.  I have had one RE tell me he stopped doing it, saying that "we know developing embryos may push abnormal cells to the outside" and basically have normal cells growing where the baby is developing.  Also, there are studies about embryos "self-correcting."  I don't want to lose any embryos that may have a chance, so I am really thinking this time we won't do it.  

    One of my good friends transferred two non-PGS embies and got beautiful twin girls out of it.  She later did another round w/ PGS and had no luck.  Just one story, but obviously many people (most people) do not do PGS and have BFP.   

    I think you should take your beautiful hatching blasts and hope they stick!!   GL!!

    TTC #1 12/2009
    BFP #1 1/2010, M/C 6 weeks
    BFP #2 6/2010, DD lost to
    congenital heart diseasewe are heartbroken.

    TTC #2 4/2011, diagnosed MTHFR, FVL
    Four natural cycles BFN; Clomid IUI BFN; Follistim IUI BFN;
    1/2012 IVF #1 BFN
    4/2012 FET BFP #3
    5/2012 7w1d u/s: anembryonic demise; M/C @ 8w.
    6/2012 found Stage II/III endo on laparoscopy, removed w/ laser.
    8/2012 IVF #2 epic fail: no viable embryos.

    Vacation, break, second opinions, on to new RE.
    1/2013 Surprise chemical pregnancy BFP #4 (break cycle), IVF #3 postponed.
    2/2013 TI w/ hormonal support, prednisone, aspirin, Lovenox, acupuncture gave us a miracle BFP #5!
    Heartbeat on U/S at 6w1d!
    Baby,please stay!!
    Our miracle baby boy arrived 10/2013!  We are so in love!!

    10/2014 Surprise BFP #6
    Our second daughter arrived in May 2015!  We are so grateful!  

    Lilypie Angel and Memorial tickers


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  • imageDahliaFlower:

    I share your concerns about PGS.  We did it with IVF 1 and 2 (round 2 we had 0 normals out of 4, so nothing to transfer).  So, I definitely know where you are coming from.  This time, I don't think we're going to do it though.  I am afraid that the PGS science may not be completely ready for prime time use.  I have had one RE tell me he stopped doing it, saying that "we know developing embryos may push abnormal cells to the outside" and basically have normal cells growing where the baby is developing.  Also, there are studies about embryos "self-correcting."  I don't want to lose any embryos that may have a chance, so I am really thinking this time we won't do it.  

    One of my good friends transferred two non-PGS embies and got beautiful twin girls out of it.  She later did another round w/ PGS and had no luck.  Just one story, but obviously many people (most people) do not do PGS and have BFP.   

    I think you should take your beautiful hatching blasts and hope they stick!!   GL!!

    Thank you so much for sharing this information!  I never even thought about this before!  Makes a lot of sense.  That is an amazing story about your friends twins!!  I hope I have the same success! 

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  • Lots of T&Ps that this works!

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    Love, luck, and prayers to my BFPB Dr. SnowflakeBride

  • Good luck! FX for you!

    Dx: PCOS and short luteal phase
    18 cycles (3 with our RE) - Metformin + Clomid + HCG booster did the trick!
    BFP #1 6/22/09 EDD: 3/2/10 DS born: 3/8/10

    TTC #2 since Dec 2011
    BFP #2 7/8/12 EDD: 3/18/12 M/C @ 9w1d: 8/16/12

  • Thanks to all your well wishes!  Had my beta this am and it was 199 8dp5dt....nurse says twins is a strong possibity!  I am seriously in SHOCK!! :)

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