Secondary IF

For thos who are experienced with injectibles...

I went for my CD 7 ultrasound.  There were a lot of small follicles on the right side and so many on my left side that they could not see my ovary.  I am not sure if this is a good thing or not.  They are having me continue Follistim for 2 more days and I go in for another ultrasound Sat. morning. 

The tech was a little concerned of overstimulating since there are so many small follicles.  She said she thought the doctor would recommend IVF if this cycle does not work.  She sounded pretty confident that IVF would work for us since I produce so many eggs.  I just don't have an extra 15K sitting around...

I am just wondering what others experiences were?  If you had a lot of follicles did only a few mature?  Anyone have too many mature?  I am terrified of OHSS.  Thanks.

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Pregnant with Letrazole (Femara) on the first cycle with DD after TTC 2+ years
TTC#2 with Letrazole (Femara) since January 2012
BFP 06.29.12 EDD 03.11.13 natural m/c 07.13.12
BFP 09.22.12 EDD 05.31.13 natural m/c 10.07.12
CP 11.09.12
BFP 01.01.13 EDD 09.15.13 d&c 01.24.13

BFP 03.26.13 EDD 12.04.13
 

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Re: For thos who are experienced with injectibles...

  • I have always been on the low dose of 75iu, so while I'll get 3-5 on each side, there are usually only 2 lead ones.

    This last, successful cycle I did lose hope because at my 2nd monitoring apt my follicles had not grown or had shrunk. And then 2 days later when the NP was having trouble finding them I asked if there was anything I could do/shift position to make it easier for her to see that side, She had the nurse push on my abdomen and up popped the missing follicle that my RE hadn't been able to find two days before. It hadn't shrunk and in fact was mature and ready to go. So maybe they just need to apply pressure to make sure they are seeing everything on the crowded side?

    In the end I had an 18 on one side and a 19 on the other when I triggered. The next closest was 14, 10, etc. 

    GL!

    Married 9-4-04

    ***PM me for my IF history***

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  • Generally, I think only a few mature.

    I'm a slow responder so I typically have a lot of small follies (10+) in each ovary for a number of days. This cycle, things didn't start growing past 10mm until CD15 and at that time I had 2-11mm, 2-12mm and probably 12 follies less than 10mm. By the time I triggered 4 days later I had a 19, 18, 2-14 and 4-6 that were less than 10.

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  • imageLeahB12:
    When I've been on 75iu of follistim, I usually have 3-4 mature follicles after about 7 days. When doing IVF, I had a total of 27 mature follicles. I wouldn't worry about OHSS unless a lot of those follicles mature. GL!

     

    I agree.  I always responded well on 75 iu of Gonal Fwith IUI.  My doctor put me on 175iu when starting IVF.  I was worried about OHSS but I think it really does take alot to get to that point.

    Good luck.

    Dx PCOS Three cycle of Clomid- BFN HSG- clear 6/09-Follistim and HCG IUI on 7/7/09 BFN 7/09- Follistim and Ovidrel IUI on 8/11/09 BFP! beta #1-342 beta #2-717 Joey was born on 5/5/10 Trying for #2 since 6/12 6/12- Gonal F and Ovidel IUI on 7/10. BFN 8/12- Gonal F and Ovidrel. IUI on 8/10. BFN 9/12- Gonal F and Ovidrel IUI BFN 10/22 Gonal F, Menopur, Ganirelex 11/4 trigger 11/6 ER 14R 10F 11/11 ET transferred one 4AA embryo beta 11/20! BFP Betas stop multiplying . m/c at 5 weeks moving on to FET if my numbers ever get back to 0!
  • Thanks ladies.  I am on 125iu.  I am curious to see what my body will do.

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    Pregnant with Letrazole (Femara) on the first cycle with DD after TTC 2+ years
    TTC#2 with Letrazole (Femara) since January 2012
    BFP 06.29.12 EDD 03.11.13 natural m/c 07.13.12
    BFP 09.22.12 EDD 05.31.13 natural m/c 10.07.12
    CP 11.09.12
    BFP 01.01.13 EDD 09.15.13 d&c 01.24.13

    BFP 03.26.13 EDD 12.04.13
     

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  • I will say my first month on Follistim I was a slow responder. It seemed as if there was a lot of little follies and that they were hanging out at about a 12, for 2 u/s's, then finally got one to a 14 they upped my dosage and got 1-3 close to 18-20ish and triggered me.  The next month they put me at the higher dosage and things seemed to move more on track.  I don't know if any of that helps, but hopefully you will get 1-3 follies to pull ahead.  I always had lots of extras, but they were deemed "too small for ovulation".  

    Don't worry about OHSS, it is rare and you don't let yourself stress out over it! 

    TTC#1: 14 months on our own (did HSG, b/w, SA);
    BFP on Cycle 14--TWINS! Identical twin boys stillborn at 19wks(1/9/10)
    3 break cycles; took clomid 50mg, BFP #2 Beta #1 35, Beta #2 338!!! Owen was born 2/11/11! 
    TTC#2: 4 cycles on clomid: BFNs
    BFP #3: Cycle #5 100mg clomid; beta #1 21; beta #2 6=CP 
    Cycle #6 break cycle TTC no meds=BFN
    Cycle #7: 150 clomid+ovidril+IUI=BFN (switched to RE)
    Cycle #8: follistem+ovidril+TI=BFN
    Cycle #9 Forced break due to cyst
    Cycle #10 follistem+ovidril+TI=BFN
    Cycle #11 follistem+ovidril+TI=BFN
    Cycle#12 Forced break due to cyst, went on BCP; did repeat HSG, Saline U/S
    Cycle #13 IVF: Follistim/Menapur ER 11-30 11 eggs, 5 mature, 4 fertilized and 3dt on 12-3; BFN
    Cycle #14: IVF#2 lupron/follistim/menopur ER 1-22, 19 eggs, 14 fertilized, 5dt on 1-27, BFP!! beta 1: 63, beta 2: 119; EDD 10-15-13; 1 frozen embie
    Miracle Surprise BFP, EDD 10-1-15; saw HB great Betas, 11weeks lost baby MC at home
    Moved forward with FET transfered solo frostie on 6-4-15, beta 1: 315, beta 2: 738, u/s showed one baby on track EDD 2-21-16
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