Natural Birth

EPO - no proof it works

This is a really good blog post, and even though it's aimed at women planning a VBAC, a lot of what she says can apply to the women on this board:

https://vbacfacts.com/2012/11/13/evening-primrose-oil-dont-use-it-if-you-are-pregnant/

Basically, there's only one study that's ever been conducted about EPO helping with labor, and it didn't seem to do much. And! it can also work as a blood thinner, which is a pretty crappy unintended side effect.

I did take EPO orally the last few weeks of my second pregnancy, but I don't think I'd do it again. 

DS1 - Feb 2008

DS2 - Oct 2010 (my VBAC baby!)

Re: EPO - no proof it works

  • The author might want to look at this study:

    Karen Alessandra Ty-Torredes, "The effect of oral evening primrose oil on bishop score and cervical length among term gravidas", American Journal of Obstetrics & Gynecology, Volume 195, Issue 6, Supplement , Page S30, December 2006.

    Which found:  

      Among seventy-one subjects who completed the study, there was a significant improvement in Bishop score in the EPO group with a mean difference of 3.68 ? 1.57 compared to 1.51 ? 1.58 for placebo (p=0.0001). Also, there was a significant reduction in cervical length with a mean difference of 0.89 ? 0.63 in the EPO group (n=38) compared to a mean of 0.42 ? 0.31 in the placebo group (n=33) (p=0.001). Pre and post-treatment Modified Biophysical profile and non-stress test were normal for all fetuses studied. Substratification analysis for parity and age of gestation showed greater impact on nulliparas and those >39 weeks age of gestation. There was no significant difference in the interval from onset or end of treatment to onset of labor between the two groups. The use of oxytocin was similar in both groups (50% in EPO and 49% in placebo group). Significantly more patients delivered vaginally in the EPO group (70% versus 51%). There was no significant difference in the birthweights of the neonates when comparing EPO and placebo group.
     
    The study cites on vbacfacts was not a study of cervical ripening, but of length of gestation and labor.  Dove  D, Johnson  P.  Oral evening primrose oil: its effect on length of pregnancy and selected intrapartum outcomes in low-risk nulliparous women.  J Nurse Midwifery.  1999;44(3):320?324.

    There was also a survey published that year, asking midwives about their use of EPO and other herbs to stimulate labor.  It's important to note that it is not a study, but rather a survey.  The two mean very different things in regard to research and methods.  McFarlin  BL, Gibson  MH, O'Rear  J, Harman  P.  A national survey of herbal preparation use by nurse-midwives for labor stimulation. Review of the literature and recommendations for practice.  J Nurse Midwifery.  1999;44(3):205?216.  

     

     

     

     

  • Loading the player...
  • 71 people is a teeny study, though. And that still doesn't lessen the risk of blood thinning that can come with taking EPO for cervical ripeness or shortening of labor.
    DS1 - Feb 2008

    DS2 - Oct 2010 (my VBAC baby!)

  • I would say that a study of 108 women is also a teeny study.
  • imageNericole:
    I would say that a study of 108 women is also a teeny study.


    Look, a lot of the low intervention community is all about how the medical community isn't practicing evidence based practices during LD. So shouldn't we be holding ourselves to the same standard? As far as I can tell, the recommendation to use EPO is just folklore and a lot of woo. Not especially compelling, in all honesty.
    DS1 - Feb 2008

    DS2 - Oct 2010 (my VBAC baby!)

  • Eh, here's the thing about herbal/traditional medicine: other than students, no one is ever going to do loads of studies that shows the stuff works. Why? There is no money in cheap, readily available herbs to fund these studies. "Proof" is a very modern, Western concept and there is so much to health beyond that. I had no problem using vaginal EPO with either pregnancy and would use it again. For various reasons, oral EPO was not a fit for me.

  • imagepixieprincss:

    Eh, here's the thing about herbal/traditional medicine: other than students, no one is ever going to do loads of studies that shows the stuff works. Why? There is no money in cheap, readily available herbs to fund these studies. "Proof" is a very modern, Western concept and there is so much to health beyond that. I had no problem using vaginal EPO with either pregnancy and would use it again. For various reasons, oral EPO was not a fit for me.

    Excellent Point! 

This discussion has been closed.
Choose Another Board
Search Boards
"
"