Experieced IVFers...

kimberm0511 · October 2012

Did you do genetic testing? Had consultation this morning and he said it can damage the embryos and can lessen the chances of it working. Dh wanted to do it, but now can't decide. Have to give an answer next week.

nawlinsgrl · October 2012

I did not do genetic testing on my embryos, but have heard that it can decrease their viability in some cases. Why did your RE bring it up? Was it just a general, hey, here's a service we provide, or was there a reason related to your treatment/dx history that the RE felt it was worth considering?

If you don't have any known risk factors to suggest using it, I probably wouldn't do it, but that's just me.

efhoping2010 · October 2012

My RE said a similar thing adding that the technology is not advanced enough in his opinion and it does damage the embryos, plus you need enough embryos to be able to do it and they have last to five days, so many ifs. We asked about it because of our recent losses and the fact we are out OOP for our third IVF cycle, two fresh, and just want to do everything possible for a success. We are doing ICSI (we have to) plus assisted hatching this time. Good luck with your decision.

kimberm0511 · October 2012

nawlinsgrl:

I did not do genetic testing on my embryos, but have heard that it can decrease their viability in some cases. Why did your RE bring it up? Was it just a general, hey, here's a service we provide, or was there a reason related to your treatment/dx history that the RE felt it was worth considering?

If you don't have any known risk factors to suggest using it, I probably wouldn't do it, but that's just me.

I just asked for my own curiousity. I have a newphew with Down Syndrome and my family thought if it was option that maybe we should do it. However, I am pretty sure I'm going to pass. There's no point if it could hurt the embryos.

Ironmom2be · October 2012

I'm lurking over here and wanted to chime in. We have to do genetic testing, I have a balanced translocation 13:14 so I have a huge risk of having an embryo with monosomy 13 or 14 or trisomy 13 or 14. We're 37 so after 2m/cs we decided to stop trying naturally and do IVF w/ PGD. My RE does arrayCGH testing on day 5 blastocysts. They draw cells the embryo is over 100 at that point from what will be the placenta, not the fetus. Different than FISH or day 3acgh that take one out of 8 cells on day 3.
We had an FET last Tuesday of two expanded blasts that tested normal they test all 46 chromosomes and I've had a hpt since 6dp5dt beta is tomorrow so please do your research into what kind of testing tm your lab does, it makes a difference. If T21 runs in your family, it might be worth the peace of mind, only you and your H can decide that.
Btw, my testing was 2950 a cycle.
Feel free to PM me if you have more questions... I hang out on the IF board!

Sorry about formatting, I'm on my phone.

DahliaFlower · October 2012

I did it twice. Second time had very confusing results, end up doing re-biopsy. I am still not sure it is the right thing to do. I think there is a significant chance of getting mis-information and being forced to make a decision based on it. I don't think I am going to do genetics the next go round. Will just wait for blast that looks good!

DahliaFlower · October 2012

Ironmom2be:
I'm lurking over here and wanted to chime in. We have to do genetic testing, I have a balanced translocation 13:14 so I have a huge risk of having an embryo with monosomy 13 or 14 or trisomy 13 or 14. We're 37 so after 2m/cs we decided to stop trying naturally and do IVF w/ PGD. My RE does arrayCGH testing on day 5 blastocysts. They draw cells the embryo is over 100 at that point from what will be the placenta, not the fetus. Different than FISH or day 3acgh that take one out of 8 cells on day 3. We had an FET last Tuesday of two expanded blasts that tested normal they test all 46 chromosomes and I've had a hpt since 6dp5dt beta is tomorrow so please do your research into what kind of testing tm your lab does, it makes a difference. If T21 runs in your family, it might be worth the peace of mind, only you and your H can decide that. Btw, my testing was 2950 a cycle. Feel free to PM me if you have more questions... I hang out on the IF board! Sorry about formatting, I'm on my phone.

And in addition to my previous remark, I totally agree w/ this PP. You have to know what you are doing and if you have a particular reason to do it. Otherwise, I would say just wait to see what makes it to blast and decide how many you want to transfer.

ChiTown Bridget · November 2012

I've had multiple losses but did not do pgd testing because of the extra cost involved. Good luck in your decision!

kimberm0511 · November 2012

Thanks for everyone's input. I am still pretty uncertain. Dh was born with clubfoot and apparently that is related to something genetic having to do with chromosomes. He told me it could be associated with other factors. I had no idea that was his issue and have no knowledge on the subject. I thought he was concerned about Down Syndrome because of my nephew. He seems very uneasy about not testing, but I'd rather just not do it. We have a few days to decide! I really appreciate everyone's thoughts. :

Experieced IVFers...

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