Infertility

BCP as part of IVF?

Okay, so I didn't realize BCP were part of IVF! Now I'm seeing a bunch of other posters including it as part of their process. (I am also not being prescribed Lupron, which it seems everyone else is!) My RE originally put me on BCP last month because he expected me to have a HSC because of a bad SHG, but my SHG came out great instead! So anyway, he has left me on BCP for 25 days (longer than my normal cycle). I had no idea it was part of the IVF process! Can anyone enlighten me as to what part it plays? What is the purpose of having me on BCP before my period, when I would be due to have my normal period around the same time anyway? Does that make sense? I'm just trying to understand.

imageimageimageimageimageimageimageimage
My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.

PAIF/SAIF Welcome!
Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins
.
First natural PG 9/27/11; mc: 1/20/12

First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right  & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13

ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
IVF #3:
NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0.  Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN

IVF #4: 
(Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...

IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
EDD 3/18/15!

Re: BCP as part of IVF?

  • My nurse refers to it as, and I quote, "Hijacking your cycle." They want complete control over what day you do what, and all that good stuff. I've read it can also help to sort of put your ovaries to "sleep" so they respond better to the stims. AND I've read that they can prevent cysts from forming that could ultimately mess with your cycle :)
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  • imagedestinyr61309:
    My nurse refers to it as, and I quote, "Hijacking your cycle." They want complete control over what day you do what, and all that good stuff. I've read it can also help to sort of put your ovaries to "sleep" so they respond better to the stims. AND I've read that they can prevent cysts from forming that could ultimately mess with your cycle :)

    I've heard most of this. I've also heard that it helps to prevent OHSS.  

    image


    Me:27, DH:28 - DX: MFI, varicocele repair Nov 2011 
    Post-Op SA: Count- 15 million, Motility- 75%, Morphology- 3% 
    IVF with ICSI - Stimming 10/4/12 - 10/13/12, Lupron Trigger
    ER 10/18/1212 eggs retrieved, 8 mature, 5 fertilized
    5 day transfer 10/23/12, 3 frosties
    Beta #1 11/5/12: 453, Beta #2 11/7/12: 1,013, DD born 7/19/13
  • imagedestinyr61309:
    My nurse refers to it as, and I quote, "Hijacking your cycle." They want complete control over what day you do what, and all that good stuff. I've read it can also help to sort of put your ovaries to "sleep" so they respond better to the stims. AND I've read that they can prevent cysts from forming that could ultimately mess with your cycle :

    this is what I was told too.
    Warning No formatter is installed for the format bbhtml
  • Except for MDLF it's not an absolute part of the protocol. Many clinics use BCP for no other reason than to batch their patients but it can suppress your ovaries as well. Plenty of people don't use Lupron. An antagonist cycle has the advantage of allowing a Lupron trigger for those at risk of OHSS and because in and of itself there is no prior suppression, an RE could conceivably manage that suppression (via BCP or EPP or none at all).

    Suppression works like this, and remember, not everyone needs it or should have it. You are always creating antral follicles and usually they just bubble up and die off before maturing. During your luteal phase some start getting recruited for your next cycle, with the goal being that one of these will reach maturity and ovulate the following cycle. Suppressing that the cycle prior to your IVF stim cycle means starting off with a clean slate and theoretically allows all your latent antral follicles to develop at a more even rate, this allowing for the maximum # of follicles to develop as close to the same size and at the same rate during your stim. What you don't want is a few bully follicles hogging all your meds and growing to maturity when the bulk of your cohort are underdeveloped and stunted. Lupron also suppresses your ovaries, but has lots of different uses in protocols at different phases and doses, so it does comes up a lot. Hope that makes sense.
    +++
  • As everyone has said, BCP is to help make sleepy quiet ovaries. It also can help in the reduction of cysts after ovulation.

    There are many different protocols for IVF. Yours without Lupron, is not uncommon. Lupron is not a part of my protocol either.

    As you hang around here and read up on people's progress/situations/protocols you'll catch on to how it works with different meds/protocols.

    BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
    TTC #1 since 1/10
    DX: Unexplained/??? MFI issues

    Our lil' lost sparks:
    5w3d loss 7/30/10 - EDD March 2011
    8w loss 4/15/11 - EDD November 2011
    8w3d loss 8/2/12 - EDD March 2013
    4w c/p loss 10/29/12 - EDD July 2013

    Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
    RPL testing all normal, Karyotyping normal

    Moving on to IVF.

    IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

    Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
    IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
    FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
    Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

    After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
    We are so in love with her.

    "I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

    Everybody is welcome!!!
  • Besides the 'quieting' the ovaries part, my dr also uses it to cycle everyone doing IVF at the same time, so we are all stimming same week, retrieval pretty much the same week etc..... he is the only Dr in the office, so this is the best way for him

     

     


    image
  • I was on BCP for 2 1/2 weeks and like some of the other girls I was told it was to "quiet my ovaries" so they would be completely suppressed. 
  • imageCousinVicki:
    Besides the 'quieting' the ovaries part, my dr also uses it to cycle everyone doing IVF at the same time, so we are all stimming same week, retrieval pretty much the same week etc..... he is the only Dr in the office, so this is the best way for himnbsp;nbsp;

    Ditto this. My dr is the only dr in the central coast of California so him and all his patients have to go down south to redondo beach for the IVF labs.
    Me 34 and DH 39 married in aug. 2002
    Did 5 round of clomid 2010 =BFN
     High levels of NK CELLS DX sept.2012 DOR:# 0.02 
    IVF #1 May 2012  ER 4, EF 2, ET 2 =BFN
    MINI IVF Oct.2012  Cancelled 10-27-12
    Ivf #3 Antagonist Protocol April 2013
    Shared cycle..Donor cycled in July Got 12 eggs 9 fertilized and 8 frozen!!
    DE FET #1 Sept. 3rd 2013 FIRST BFP EVER 5dp5dt
    miscarried Sept 24th at 5 weeks 5 days
    Etopic  D&C and hysterscopy Nov 5 2013
    dx with pre genetic blood clotting dec 2013
    FET #2 Jan 31st  2014 
    Miscarried for a second time again at 5 weeks 5 days
    Currently fostering to adopt an amazing little 1 year old boy..P.J!
    FET#3  is Oct 29th 2014
    BFN on fet #3
    Last and FINAL FET coming JAN 28th 2015
    Everyone Welcome






  • Thanks to all for responding! Thanks to Destiny for making it simple. And thanks to Edwina for filling in the details. This is why I love this board!!


    imageimageimageimageimageimageimageimage
    My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.

    PAIF/SAIF Welcome!
    Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins
    .
    First natural PG 9/27/11; mc: 1/20/12

    First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
    IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right  & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
    ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
    IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13

    ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
    IVF #3:
    NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
    ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0.  Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN

    IVF #4: 
    (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
    ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
    ***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...

    IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
    BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
    2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
    2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
    2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
    IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
    5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
    6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
    7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
    EDD 3/18/15!

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