Need advice/OHSS

djma81 · September 2012

Hey guys....I need your advice! I just got back from my first monitoring appt since starting STIMS on Saturday. I have been feeling a bit nauseous and quite uncomfortable for the last day or so. On my US today I'm showing 17 follies on the right and 28 on the left. Lining is at 9....at baseline it was 2.5. My RE is adding Ganirelex to my routine tomorrow evening and keeping all other meds the same (150 of both follistem and Menopur). She is concerned that I may develop OHSS, and will have to freeze the embryos before the transfer stage. Of course if this s the best thing for me and the embryos I'm okay with it, however I would much rather do a fresh transfer. My question is what can I do, if anything to prevent OHSS from setting in?

notquiteblushing · September 2012

How big were the biggest follicles measuring? And do you know your estrogen level? I ask because my estrogen level was 4000 and I read that sometimes you get cancelled if it's that high but my nurse said that it probably wouldn't happen in my case. (She explained it better but I was barely conscious, sorry.)

I would call and tell them your concerns and ask for input. Also I think it's probably too early to do anything to ward off OHSS if you've only been stimming for four days as I thought it usually started after trigger. Anyway I've been drinking tons of Gatorade. Good luck.

djma81 · September 2012

Thanks for the response. Pretty sure the biggest follicle was 12, my E2 level was just drawn this am so don't ave those results back yet. I was cancelled my first go around with another RE. My levels shot way up to like 2000...,,they drastically dropped my meds and then my follies stopped growing. My E2 went down to like 200 over night! So they cancelled me at that point, I never made it to ER. I guess there really isn't much else I can do other than Gatorade and rest. Thanks again for your prompt reply!

CutieGirlLissie · September 2012

Speaking from experience (my last cycle ended in OHSS and freezing all my embies) there isn't much that can be done that your doctor isn't already doing. He put you on Ganirelix which may help. He might also have you trigger with Lupron instead of HCG. But unfortunately if you are a follie machine and produce a lot it might still happen. I know the idea of having to be delayed a month really sucks but if it makes you feel any better, there are a lot of studies coming out now that indicate FETs might actually have a higher success rate then fresh cycles. GL and I REALLY hope you don't get OHSS!

Ironmom2be · September 2012

I'm sorry you're faced with this...I know how you feel : I triggered last week with an E2 of 9224. My RE did a freeze all and put me on dostinex for 8 nights starting on trigger night. I do not have OHSS at all. So maybe ask about that? Good luck, even reducing my meds couldn't stop my rising E2.

bry238 · September 2012

I ended up getting OHSS after my retrieval and I was devastated that my fresh transfer was cancelled. However, I spoke to many drs at my clinic and they all said the same thing...there is nothing that could've been done, BUT the good news is, if you have quality embryos and were only cancelled due to OHSS, an FET actually has higher success rates than a fresh transfer. Reason being that the OHSS gets a whole lot worse if the embryo implants. In addition, your body is rid of all those stimming hormones, and your ovaries and uterus return to its natural state, so its more similar to a spontaneous cycle verses a medicated cycle.

It stinks, but it really isn't that bad. By the time your cancelled, you will already get your period a week later, so your really only delaying the process 3 weeks, 4 tops. I was cancelled on Sept 6 and have my FET tomorrow.

Best if luck avoiding OHSS, but if you do get it, just remember to drink plenty of fluids and get lots of bed rest, and it usually goes away in a week or so. GL!

Scoop77 · September 2012

I'd echo what others have said about not fearing an FET too much. I've gone through a fresh and most of a frozen cycle (transfer is next Tuesday) and let me just say the stress is much lower with this FET. I actually felt like I wasn't doing anything for most of this cycle, and it was a TON cheaper with fewer monitoring appointments and blood draws. I'm crossing my fingers for you either way!

djma81 · September 2012

Thanks for the support and info ladies! I'm just going to take it one day at a time. Go back to see RE on Friday.....will keep you all posted!

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