i didn't have these during my last IVF attempt (nor did i take any during any other cycle), but they came with my meds the other day. I will obviously ask at my baseline, but any info would be helpful:
Estrace can be used to suppress your ovaries if taken before the stims (estrogen priming), and to support/thicken your lining if taken during or after your stim start. It also comes in injection and patch form and the pills can be inserted or taken orally. YMMV.
Methylprednisolone (aka Medrol) is a corticosteroid and aids implantation. Most often Rx between ER and ET.
Doxy is an antibiotic to prevent infection from the ER and ET, but mainly ER.
Everything PP have said. I was also told that the medrol lowers the immune response and helps prevent rejection of the embryo, particularly when ICSI or AH are used. And it tastes TERRIBLE.
I took all three at various points, along with dexamethasone to lower cortisol levels.
I was also told that the medrol lowers the immune response and helps prevent rejection of the embryo, particularly when ICSI or AH are used. And it tastes TERRIBLE.
This! I have 2 left and will be super excited to see it go! The second it touches your tung the disgusting taste lasts for a minimum of 30 minutes!
Methylprednisone aka Medrol for assisted hatching, so your body doesn't reject the modified embryo/blast. Doxycycline is an antibiotic to counteract all the lovely foreign tools that go into your body that could cause infection.
Us: 39(me)/41(he). TTC since April '11. DOR/MFI. March '12: surgery to remove fibroids, cysts, and endometriosis.
IVF #1: 9/13/12. ER: 9/25. 3R, 2M, 1F. ET: 9/28 (1-6B). Beta: moved from 10/11 to 10/10: BFN.
IVF #2: 11/12 cycle postponed due to Sandy and then cancelled due to elevated E2.
IVF #2.1 cancelled due to cyst.
IVF #2.2: 2/2/13. Converted to IUI. BFN
IVF #3.0: 3/2014. BCP & Microdose Lupron. Cycle cancelled due to poor response.
IVF #4.0: 2/2015. EPP @ new RE. ER: 3/8. 3R, 3M, 1F. ET: 3/11 (1-8cell). 3/23 Beta: 16.9. 3/25 Beta: 71.6. 3/27 Beta: 300. 3/29 Beta: 800 3/31 Beta: 1816. 4/1 Beta: 4342. m/c at 6w2d. Goodbye little one. I loved you already.
P/SAIF Welcome. My Blog
I was also told that the medrol lowers the immune response and helps prevent rejection of the embryo, particularly when ICSI or AH are used. And it tastes TERRIBLE.
This! I have 2 left and will be super excited to see it go! The second it touches your tung the disgusting taste lasts for a minimum of 30 minutes!
It really is one of the worst pills I've ever taken - why can't they coat the outside with something?! I find some juice helps - but only a little bit... YUCK - just thinking about it!
TTC #1 since 6/09 Dx: PCOS and MFI 3 IUIs, 4 IVFs = BFFN 3rd RE: IVF #5/FET = BFP 14dp5dt=1170 16dp5dt=2573 1st u/s=TWINS! It's a Boy and a Girl!
I was also told that the medrol lowers the immune response and helps prevent rejection of the embryo, particularly when ICSI or AH are used. And it tastes TERRIBLE.
This! I have 2 left and will be super excited to see it go! The second it touches your tung the disgusting taste lasts for a minimum of 30 minutes!
Oh joy! I just picked up my Rx for this yesterday...don't have to start it for a few more weeks but still....
For the medrol...I found that chewing up a bunch of crackers or bread, then inserting it into the middle of the chewed up lump and swallowing it quickly seemed to work best.
I agree that they should coat it. With something nice tasting. Like Advil.
Everything PP have said. I was also told that the medrol lowers the immune response and helps prevent rejection of the embryo, particularly when ICSI or AH are used. And it tastes TERRIBLE.
I took all three at various points, along with dexamethasone to lower cortisol levels.
This. It was so bad, the taste stayed in my mouth for ages. Don't put it on your tongue first, then reach for the water! Drink a mouthful of water first, then pop it in. Trust me
TTC since March 2009 // Me and DH - 28 Testing Summer/Fall 2010 - Unexplained IF IUIs #1-4 ~ Clomid/Ovidrel/TI/IUI ~ all BFNs IUI #5 ~ Femara/Ovidrel/TI/IUI ~ BFN IUIs #6-9 ~ Research Study Meds/Pregnyl/TI/IUI ~ all BFNs IVF Consultation, More Testing Diagnostic Cycle ~ Mucinex/Progesterone/TI ~ BFN IVF #1 ~ Menopur/Bravelle/Ganirelix/Novarel/Progesterone/Lupron 7R, 6F // 2 transferred // 3 frosties ~ BFN FET #1 ~ Estrace/PIO/Lupron 3 thawed // 2 transferred // 1 lost // no more frosties ~ BFP!! Beta #1 - 456 // Beta #2 - 1176 // Beta #3 - 2933 // Beta #4 - 6753 EDD: May 16, 2013
Threatened MC at 6w2d Bedrest for SCH // 6w2d through 10w1d Elevated TSH and Lazy Thyroid DX @ 10w - Started Synthroid Finally released from RE at 13w
Everything PP have said. I was also told that the medrol lowers the immune response and helps prevent rejection of the embryo, particularly when ICSI or AH are used. And it tastes TERRIBLE.
I took all three at various points, along with dexamethasone to lower cortisol levels.
This. It was so bad, the taste stayed in my mouth for ages. Don't put it on your tongue first, then reach for the water! Drink a mouthful of water first, then pop it in. Trust me
I chased mine with an Oreo. Or two... depending how long I could still taste that stuff for. It's really, really bad.
Dx Hypothyroid 2009 - Dx PCOS 3/2011- TTC since March 2010
DH: Perfect
April 2011 - HSG - Normal/Clear but tilted uterus
May 2011 - Start Metformin
June 2011 - SIS - Arcuate but normal uterus
July 2011 - 100mg Clomid Cycle cancelled - No response
August-September 2011 - Break for oral & eye surgery
Oct 2011 - Femara 7.5mg + Metformin 1500mg + Novarel trigger + IUI #1 = BFN
Nov-Mar 2012- Break due to DH ship schedule
April 2012 - Femara 7.5mg + Metformin 1500mg + Novarel trigger + IUI #2 = BFFN
May 2012 - Femara 7.5mg + Metformin 1500mg + Trigger + IUI #3 = BFFN
June 2012 - Femara cycle cancelled - No response
Jul-Aug 2012 - Break, getting our financials in order
September 2012 - IVF w/ ICSI and AZH
9/11/12 - ER (34 retrieved, 24 mature, 18 fertilized)
9/16/12 - ET - 5dt of 2 perfect blasts and 7 frosties!!!
Beta #1 - 10/1/12 - BFP!!! 2000+
Beta #2 - 10/3/12 - 4881
Beta #3 - 10/5/12 - 8570
First u/s - 10/9/12 - 6w0d - 2 sacs!!!
Second u/s - 10/16/12 - 7w0d - 2 babies with 2 strong hbs!!
First OB appt - 11/5/12 - "Baby A" looks great, good hb and movement, measuring 10w0d "Baby B" stopped growing at 8 weeks :0(
12/5/12 - Baby looks great at 14w2d - 165bpm heartrate!
January 4th, 2013 - Lost our Baby Girl, Faith at 18w3d
Emergency D&C to clear infection
We love you and miss you little one
Yep, yep on the tasting bad. I would put apple sauce in my mouth, then the pill and swallow.
Methylpred. decreases inflammation.
Doxy can make you nauseated so definitely take with food. I also found I had to take it in the middle of a meal, not at the beginning or end.
Me 33. DH 32. TTC Since 6/2011.
12/2012-m/c, CP.
DH: MFI. CCT/HSG/day 3 blood work-all nl.
IVF#1 ER- 8/7/12, ET- 8/10. beta 8/25 neg, I did not respond as expected. AMH: 0.88.
IVF#2 BCP-10/19. Micro flare Lupron-Nov: It's a bust.
IVF#3 Planned for Feb '13 with a long lupron protocol
ON OUR OWN!!! BFP- 1/12/13. Yay! EDD 9/18, now EDD 9/25
Re: IVF: can someone tell me what these pills are for?
methylprednisole is a low grade steroid to help with inflammation. I started taking it the day of my trigger shot.
doxycycline is an antibiotic that I start taking tonight (night of ER) through the ET.
Estrace can be used to suppress your ovaries if taken before the stims (estrogen priming), and to support/thicken your lining if taken during or after your stim start. It also comes in injection and patch form and the pills can be inserted or taken orally. YMMV.
Methylprednisolone (aka Medrol) is a corticosteroid and aids implantation. Most often Rx between ER and ET.
Doxy is an antibiotic to prevent infection from the ER and ET, but mainly ER.
https://www.ivf-indiana.com/education/ivf-patient-info.html
Everything PP have said. I was also told that the medrol lowers the immune response and helps prevent rejection of the embryo, particularly when ICSI or AH are used. And it tastes TERRIBLE.
I took all three at various points, along with dexamethasone to lower cortisol levels.
Antagonist IVF 7 retrieved, 4 fert w/ICSI&AH, 2 blasts transferred. Beta #1 9/20: 367 Beta #2 9/22: 841
I have the same meds.
Doxy I started taking two days before ER - day of trigger shot
Estrace I start 2 days post ER ( Saturday )
and same with Methylpred. the steroid to stop inflammation
1st cycle of IVF w/ ICSI = started bcp's 8/2/12, lupron 8/22/12, stims 9/7/12,ER 9.20.12 ET 9/23/12 3dt 1 6A and 1 4B; Positive HPT 10/2/12, BFP Beta 10/3/12: 38!, 2nd Beta 10/5/12 28
IVF #2 w/ ICSI = bcp 3/1, ER/ET planned for the week of 4/8
This! I have 2 left and will be super excited to see it go! The second it touches your tung the disgusting taste lasts for a minimum of 30 minutes!
IVF #1: 9/13/12. ER: 9/25. 3R, 2M, 1F. ET: 9/28 (1-6B). Beta: moved from 10/11 to 10/10: BFN.
IVF #2: 11/12 cycle postponed due to Sandy and then cancelled due to elevated E2.
IVF #2.1 cancelled due to cyst.
IVF #2.2: 2/2/13. Converted to IUI. BFN
P/SAIF Welcome.
My Blog
It really is one of the worst pills I've ever taken - why can't they coat the outside with something?! I find some juice helps - but only a little bit... YUCK - just thinking about it!
Dx: PCOS and MFI
3 IUIs, 4 IVFs = BFFN
3rd RE: IVF #5/FET = BFP
14dp5dt=1170 16dp5dt=2573
1st u/s=TWINS!
It's a Boy and a Girl!
Born at 34w3d!
Oh joy! I just picked up my Rx for this yesterday...don't have to start it for a few more weeks but still....
[spoiler] My Blog: Grow Baby Grow
BFP #1: 12/2009 m/c 1/2010 BFP #2: 6/2010 m/c 8/2010
BFP #3: 10/2011 ectopic 11/2011 (right tube removed, learned left tube was probably nonfunctional due to scar tissue from infection after m/c)
3 failed IUIs, IVF #1: 18R, 12M, 10F, 3 poor quality 5d embryos transferred= BFP #4!!!!!
Betas: 9dp5dt: 64 ~14dp5dt: 91 (expecting miscarriage, doubling time of 236 hours) ~16dp5dt: 200~18dp5dt: 500
First Ultrasound at 6w2d revealed two sacs, only one with a heartbeat
LK arrived after 42 weeks on August 14, 2013! Beautiful, healthy, and happy!
TTC#2: IVF booked for April 2015
Surprise BFP#5 February 19, 2015 EDD: November 2, 2015
Betas: 10dpo: 10, 14dpo: 77, 17dpo: 270
First Ultrasound at 5w1d showed a miracle UTE baby! And right ovary ovulation to left fallopian tube.
JD arrived at 38 weeks on October 20, 2015.
TTC #3: Since October 2017. BFP #6 July 2, 2018 EDD: March 16, 2019 [/spoiler]
For the medrol...I found that chewing up a bunch of crackers or bread, then inserting it into the middle of the chewed up lump and swallowing it quickly seemed to work best.
I agree that they should coat it. With something nice tasting. Like Advil.
Antagonist IVF 7 retrieved, 4 fert w/ICSI&AH, 2 blasts transferred. Beta #1 9/20: 367 Beta #2 9/22: 841
This. It was so bad, the taste stayed in my mouth for ages. Don't put it on your tongue first, then reach for the water! Drink a mouthful of water first, then pop it in. Trust me
TTC since March 2009 // Me and DH - 28
Testing Summer/Fall 2010 - Unexplained IF
IUIs #1-4 ~ Clomid/Ovidrel/TI/IUI ~ all BFNs
IUI #5 ~ Femara/Ovidrel/TI/IUI ~ BFN
IUIs #6-9 ~ Research Study Meds/Pregnyl/TI/IUI ~ all BFNs
IVF Consultation, More Testing
Diagnostic Cycle ~ Mucinex/Progesterone/TI ~ BFN
IVF #1 ~ Menopur/Bravelle/Ganirelix/Novarel/Progesterone/Lupron
7R, 6F // 2 transferred // 3 frosties ~ BFN
FET #1 ~ Estrace/PIO/Lupron
3 thawed // 2 transferred // 1 lost // no more frosties ~ BFP!!
Beta #1 - 456 // Beta #2 - 1176 // Beta #3 - 2933 // Beta #4 - 6753
EDD: May 16, 2013
Bedrest for SCH // 6w2d through 10w1d
Elevated TSH and Lazy Thyroid DX @ 10w - Started Synthroid
Finally released from RE at 13w
~~ My IF Blog ~~
I chased mine with an Oreo. Or two... depending how long I could still taste that stuff for. It's really, really bad.
Dx Hypothyroid 2009 - Dx PCOS 3/2011- TTC since March 2010
DH: Perfect
April 2011 - HSG - Normal/Clear but tilted uterus
May 2011 - Start Metformin
June 2011 - SIS - Arcuate but normal uterus
July 2011 - 100mg Clomid Cycle cancelled - No response
August-September 2011 - Break for oral & eye surgery
Oct 2011 - Femara 7.5mg + Metformin 1500mg + Novarel trigger + IUI #1 = BFN
Nov-Mar 2012- Break due to DH ship schedule
April 2012 - Femara 7.5mg + Metformin 1500mg + Novarel trigger + IUI #2 = BFFN
May 2012 - Femara 7.5mg + Metformin 1500mg + Trigger + IUI #3 = BFFN
June 2012 - Femara cycle cancelled - No response
Jul-Aug 2012 - Break, getting our financials in order
September 2012 - IVF w/ ICSI and AZH
9/11/12 - ER (34 retrieved, 24 mature, 18 fertilized)
9/16/12 - ET - 5dt of 2 perfect blasts and 7 frosties!!!
Beta #1 - 10/1/12 - BFP!!! 2000+
Beta #2 - 10/3/12 - 4881
Beta #3 - 10/5/12 - 8570
First u/s - 10/9/12 - 6w0d - 2 sacs!!!
Second u/s - 10/16/12 - 7w0d - 2 babies with 2 strong hbs!!
First OB appt - 11/5/12 - "Baby A" looks great, good hb and movement, measuring 10w0d
"Baby B" stopped growing at 8 weeks :0(
12/5/12 - Baby looks great at 14w2d - 165bpm heartrate!
January 4th, 2013 - Lost our Baby Girl, Faith at 18w3d
Emergency D&C to clear infection
We love you and miss you little one
Yep, yep on the tasting bad. I would put apple sauce in my mouth, then the pill and swallow.
Methylpred. decreases inflammation.
Doxy can make you nauseated so definitely take with food. I also found I had to take it in the middle of a meal, not at the beginning or end.