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Elevated lh:fsh Ratio

SarahMeyer0823SarahMeyer0823 member
in Trouble TTC

Hi Ladies -

I spoke to the physician's assistant today at my RE's office. She called to give me the results of my CD3 b/w. 

FSH - 5.79
LH - 19.6
Estrogen below 20 which is normal for CD3

Anyway, she basically said I have an elevated lh:fsh ratio, which I already suspected from other bloodwork drawn 6 months ago (although not on CD3). So, I'm just wondering if anyone else has had experience with this? Could this be the thing that "finalizes" my PCOS diagnosis? The only other "symptom" of PCOS I have is weight around the stomach. I'm currently taking Clomid to see if this helps me ovulate, since I haven't since getting off the pill last October.

Any insight/experiences would be appreciated. Thanks!! 

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My Blog!
TTC #1 since 11/1/2011
Me: 28 DH: 29
DX: Hypothyroidism (2004) & Possible PCOS (2/2012)
CD3 b/w: Elevated LH:FSH ratio HSG: All clear! Y-shaped Uterus; SA: Normal
Round 1 of Clomid (50mg) 8/28-9/1: BFP!
BFP #1: 9/23/12 Edd: 6/4/2013. M/C 9/28/12 @ 4w4d
Round 2 of Clomid (100mg) 10/3-10/7: BFP!
BFP #2: 11/3/12 Edd: 7/16/2013. mmc discovered at 18w2d (our baby girl stopped developing at 15w3d due to Down's Syndrome). d&e 2/15/13
3/28/13: "quite a few" uterine polyps and scar tissue discovered.
Hysteroscopy (4/16/13): Polyps, Scar Tissue removed. Septate confirmed & removed.
Appt with new RE 5/30/13
Surprise BFP (with no treatment!) 6/30/13
Our perfect little boy was born 3/11/14 - 9lbs 2oz, 21 1/4"

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Re: Elevated lh:fsh Ratio

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    honeygirl500honeygirl500
    It can mean pcos. I believe you need two findings for a dx of pcos. Things such as weight issues or hairiness can count.  Just out of curiosity what did your us show? Any other abnormal blood work?
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    TTC since April 2010
    Diagnosed w/PCOS as a teen
    Aug 2011 dx MFI
    Oct 2011 referral to RE 1500mg Met
    5 Rounds of Clomid
    On waiting list for injects/IUI
    P/SAIF Welcome
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    beth9409beth9409 member

    I am not that familiar with using the LH/FSH ratio for diagnosing PCOS. My RE uses the following to diagnose PCOS: long/irregular cycles (with no other explanation), polycystic ovaries on ultrasound, and high testosterone. She said that you need at least two of the three to confirm PCOS.

    Here is an abstract for a study I found about LH/FSH ratio and PCOS.

    https://www.ncbi.nlm.nih.gov/pubmed/14737959

    TTC#1 since 5/2011
    DX: Hypothyroidism, PCOS, Myasthenia Gravis, Aplastic Anemia, one copy MTHFR DH SA: count 52% motility (slow progressive), 0% normal morph
    June-July 2012: Clomid cycles=BFNs
    August 2012: New RE, started Metformin, Letrozole 7.5mg+TI=BFN Sept. 2012: IUI#1: Letrozole 7.5mg=BFN
    Oct. 2012: IUI#2 Letrozole 7.5mg+Dexamethasone=BFN
    Nov '12-March '13 on a break
    April 2013: IUI#3 Letrozole 7.5mg+Dexamethasone=BFN
    June 2013: IVF#1  Follistim/Menopur/Ganirelix =BFN, 3 Frosties
    August 2013: FET#1=BFP 8/20/13,  EDD 4/30/13, MMC 10/1/13
    December 2013: IVF#2 Follistim/Menopur/Ganirelix=?
     ~PAIF/SAIF Welcome~

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