







My BLOG: www.ivfbabyquest.wordpress.com -Update
- old blog.
PAIF/SAIF Welcome!
Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age.
Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins.
First natural PG 9/27/11; mc: 1/20/12
First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
IVF #1:
10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s
showed 6 follicles in my right & 9 in my left. Rx: 150 Bravelle &
150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET
11/2/12: CANCELED. All 5 came back from PGS as having "severe
abnormalities."
IVF #2:
1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left.
Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every
morning. hCG Trigger 1/16/13
ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13:
CANCELED. All embryos (he even sent the ones not growing) came back from PGS as
having "multiple severe abnormalities."
IVF #3: NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3
follicles in my right & 4 in my left. Rx: 150 Bravelle& 150
Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0. Five day ET 3/16/13: one
early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
IVF #4: (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline:
FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5
follicles in my right & 4 in my left. Rx: 225 Bravelle& 225
Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2
(Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd
stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and
focus on living childless, due to the extremely poor quality of my
eggs.
***Decided
to stop trying and live CFNBC. I couldn't adjust. So, six months later...
IVF #5: Changed RE. Going to one of the big name clinics now.
OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
EDD 3/18/15!
Re: New to this Board
Welcome.
I hope you find the support you need here and good luck on your TTC journey.
I'm 42 and I opted to do IVF with PGD so that I could at least increase my chances of a chromosomally normal embryo. I'll be doing a FET next week and implanting one of them. I felt that at my age, it was the best option for me for the best chances. However, PGD isn't for everyone and it might not be possible given your ovarian reserve.
I had a saline sonogram that showed a little irregularity. I opted to repeat the study and it did turn out normal. But if it didn't, the next step would have been a hysteroscopy.
Best of luck in you choices and I hope for the best for you. You will find a great amount of support here among these wonderful women.
TTC 10/11. IUI 2/12. BFP 3/8/12. 4/26/12 missed mc. RE consult 5/17/12. IVF #1 ER 7/13/12 53R, 41M ICSIed, 32F, 8 5d, 6 6d blasts - all PGD/frozen. PGD results 1 normal M and 1 normal F, 1 maybe M. FET 9/6, transferred 1 F embie. Beta 9/15 BFN. FET#2 planned for 11/2012 put off until 2013. Surprise BFP 11/21/12!! My son was born on 7/24/13!
Welcome! Lets keep moving up the age...I'm 44...lol
Seriously though this group of ladies on here are awesome. I don't know what I would of done without them. Very supportive. With only one chance at this since everything is so expensive and of my age we are in the process of using DE. I wish you the best of luck on this journey!
ME:46 MH:44 DE IVF 2014
Met with RE 4/11. 2 IUI's BFN. DE best option. Switched clinics to do "shared" program. Had to retake all tests and a mamm that put me behind and then on a DE waiting list for 12 months. Picked a donor!! (10/13/13) Got matched. Estimated transfer in December. After 2.5 years of patiently waiting I will finally cycle....can hardly believe it. DE cycle got cancelled. One of her tests came back positive. Waiting for another donor. Donor picked!! (1/18/14)
DE IVF #1 (4/26) BFN DE FET #1 (6/4) BFP! Beta 1=339 Beta 2=852 Beta 3=9957 EDD 2/22/15!!
Welcome & I wish you lots of luck and a short stay!
Moving back down 2 yrs now... I am 42, just got married for the 1st time in June & we are TTC naturally. My DH has no interest in me taking any type of drugs, IVF or IUI - so if it doesn't happen on its own we are sol. I too agree on not taking any drugs to help the pregnancy along, but would have considered IUI - now that I understand what they do. I am charting my temp & mucous & also using OPK (ovulation predictor kit strips) - that is about all I can do.
I did add Folic Acid & B6 to my diet about 3 mths before we started TTC. We are only on our 3rd mth ttc, but are realistic that it may not happen for us. If it doesn't, then my DH said he will be taking me on lots of nice vacations... This cycle looks promising for us & the last two days I have been so tired after dinner, that I have been going to bed early. Im hoping that is a symptom...
Good luck on your journey & the ladies here are very helpful & full of knowledge.
Welcome to the board! Women are awesome-- a TON of knowledge, experience, and the ovaries to give each other a kick in the pants when needed or, as is usually the case, encouragement and hugs.
I'm "only" 37 (38 in 2 months) and have not reached the IUI stage, although that appears to be in the very near future. So I don't have any advice on your particular dilemma, but I wanted to welcome you and wish you GL!
<br /> My Ovulation Chart</a>
Welcome to the board. Lots of women at 41 have successful pregnancies. All you can do is try. You won't know until you do. I just turned 39 and have been trying since I was 37. I've done 4 IVFs and never had a good embryo. I also don't make many eggs. You have a better shot if you can produce a bunch of eggs but there are always some who get lucky with a golden egg. I am starting a donor egg cycle soon as I just didn't believe I'd get lucky.
Do you know what your ovarian reserve is? (ie CD3 FSH/E2 and AMH and AFC)
TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
5 IUI's: 2/11 to 6/11 and 1/12= BFN
OE IVF#1-4 8/11-6/12= all BFN
DE IVF#1 11/12 bad embryos= BFN
DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
DE IVF #3 1/14 ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d
DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!
K & K born 11/21/14 at 38wks 4 days
SAIF/PAIF Welcome
http://waitingforraintostop.wordpress.com
Screw the stats. Stay hopeful. You're not out yet.
Just my opinion.
____________________________
Breast Cancer diagnosis 12/01/2010 - Survivor and Cancer free as of 03/22/2011
BFP#1 04/12/2011 - fetal demise - MC 05/28/2011
BFP#2 10/14/2011 - fetal demise - MC 12/13/2011
BFP#3 05/30/2012 - fetal demise - MC 07/23/2012
IVF#1 02/14/2013 - 2 Beautiful Blasts transferred
BFP#4 02/25/2013 - BFP - MC and ectopic 03/06/2013
IFV#2 07/02/2013 -BFP#5 - 07/07/2013
1st Beta 07/11/2013 - 483 (9dp5dt) - 2nd Beta 07/13/2013 1006 (11dp5dt)
1st U/S 07/31/2013 - TWINS! "The Minions"
IVF#3 BFP#6 09/01/2015 6dp5dt
1st Beta 09/05/2015 - 105 - 2nd Beta 09/08/2015 335
1st U/S 09/22/2015 - .......
DD born 12.21.09, conceived w/ injects and IUI
TTC#2 since Nov 2011
BFP 2.6.12 m/c 6w5d | BFP 5.25.12 c/p
-Back to the RE-
3 medicated IUIs, all BFN
-Taking a break from treatment-
BFP 11.20.12 ~ EDD 7.28.13
My Chart
emikat- Thank you! I'm curious, why does egg supply have an effect on PGD? We are planning/hoping to use PGD. Good luck with your implant!!!
happywifem- Thank you! I'm tired, too.
BeckyP005- I love that you're 44! That makes me feel like I've not run out of time. Good luck to you!
Qzees- Thank you! I wish you much luck, trying naturally. Obviously that would be the best, being able to skip the medical interference!
danieleand- Thanks! You have a great attitude! Good luck to you!
Mrs.McIris- We're definitely trying! I give you so much credit for FOUR IVFs! We only have resources for one, maybe two, so our fingers are crossed! I don't know my ovarian reserve. When we go for our consult next week, I'll ask for a copy of my blood results.
Llamamama- Thank you!
robbensm- Thanks! I was just too weak to fight last night, but today's another day. I agree...one step at a time, but it's hard not to get ahead of myself.
BabyVDM- Yes, the Dr.'s stats brought tears to my husband's eyes, which was most difficult for me. Thanks for your support!
jrtmom- Thank you!
Abeille- Thank you! Here's hoping!
My BLOG: www.ivfbabyquest.wordpress.com -Update - old blog.
PAIF/SAIF Welcome!
Me: 42, Hubby: 35, TTC since Jan 2010. Dx: DOR due to advanced maternal age. Also: Hypothyroidism (100mcg Levothyroxin). Positive for MTHFR (hetero-C677T), Factor V Leiden, and Fragile X (on DH side). Taking pre-natal vitamins.
First natural PG 9/27/11; mc: 1/20/12
First RE visit: 8/8/12, Saline Sonogram: 8/28/12, IVF injection class: 10/11/12, add FaBB Tab for FVL, +Vitamin D.
IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Prog- 0.3 The u/s showed 6 follicles in my right & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 10/21/12: Add Ganirelix SQ every morning.
ER 10/28/12: 13 Retreived. 7 Mature. 6 Fertilized. 5 Made it to PGS. ET 11/2/12: CANCELED. All 5 came back from PGS as having "severe abnormalities."
IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ nightly. 1/11/13: Add Ganirelix SQ every morning. hCG Trigger 1/16/13
ER 1/18/13: 9 Retrieved. 5 Mature. 5 Fertilized. 2 Made it to PGS. ET 1/23/13: CANCELED. All embryos (he even sent the ones not growing) came back from PGS as having "multiple severe abnormalities."
IVF #3: NEW RE! 3/1/13 Baseline: FSH- 9.6, E2- 61, Prog- 0.94, 3 follicles in my right & 4 in my left. Rx: 150 Bravelle& 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ.
ER 3/11/13: 6R, 2M, 2F. Day 3: one 8 cell, grade 0. Five day ET 3/16/13: one early blast, grade Fair. 3/24/13 AF came a day before beta. BFN
IVF #4: (Added acupuncture to this cycle.) 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Prog- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right & 4 in my left. Rx: 225 Bravelle& 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM.hCG Trigger 4/3/13 SQ.
ER 4/5/13: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). Five day ET 4/10/13: two blastocysts (the 3rd stopped growing.) Beta 4/18/13: 2.5 BFFN. RE recommends we stop trying and focus on living childless, due to the extremely poor quality of my eggs.
***Decided to stop trying and live CFNBC. I couldn't adjust. So, six months later...
IVF #5: Changed RE. Going to one of the big name clinics now. OWDU: 10/29/13. Update: HORRIBLE experience. Disgusted and distraught at their complete unprofessionalism and how much money and precious time they cost us. Sickening. Have now changed RE again. New Patient appt. 1/30/14.
BFP! Out of nowhere, I got KU the old fashioned way! POAS 1/26/14 - Positive! FDLM 12/30/13. Beta #1 16dpo= 373. Beta #2 18dpo= 801. EDD 10/6/14
2/4/14 1st U/S revealed a 5wk2day sac but no fetal pole. Started 200mgs of progesterone suppositories daily
2/11/14 2nd U/S revealed a perfect 6wk1day "diamond ring" embryo with a beating heart! 138bpm! Add 1mg folic acid and 40mg Lovenox
2/25/14 3rd U/S: perfect 8w1d embryo, 178bpm. 3/6 start spotting. 3/11 10w1d U/S shows no heartbeat. Scheduling D&C. The Stork has forsaken me again.
IVF #5.2: New in-state RE. Supplement priming for 1.5 cycles prior to start of cycle, including DHEA 50mg (stopped 5/15), CoQ10 200mg 2x/day, L-Arginine- 1000mg 2x/day (stopped 6/5 due to cold sore!), myo-inositol- 2g 2x/day, melatonin- 3mg, and Neevo (prenatal for MTHFR).
5/16/14 Day 2 bw cycle prior: FSH- 12.22, E2- 38.37, Prog- 1.35, LH- 9.46. 6/2/14 Day 19 bw: Prog- 23
6/12/14 Baseline: E2- 122.7, Prog- 0.4. 5 follicles in left, 4 follicles in right. Start stims: 375IU Follistim & 150IU Menopur. 6/19 Increase Follistim to 425IU, Menopur still 150IU. 6/18 add Ganirelix. 6/23 Ovidrel trigger SQ. 6/25 ER: 8R, 8M, 5F naturally. Start Medrol & Doxy. 6/26 Start Endometrin. 7/2 Start Lovenox.
7/8/14 Beta= 137.4 BFP!!! (My first from IVF!) E2- 1109, Prog- >60. Stop CoQ10, myo-inositol, and melatonin. 7/9 2nd Beta= 281.4. TSH- 2.70. Increasing Synthroid to 100mcg daily. 7/24 6w3d u/s measured 6w3d, hb: 121bmp! 8/5 8w1d u/s measured 8w3d, hb: 164bpm! Graduated from RE to OB. Now I just need to find an OB!
EDD 3/18/15!
For PGD you have to produce enough embryos that make it to either day 3 or day 5 to do the biopsy. My RE does the biopsy on day 5, so they have to make it to the blastocyst stage. After that, they freeze them while they wait for the results. He said that one ideally would hope for about 5 or 6 of them to test. If you can't produce that much then it's generally not recommended to do PGD. After going through it, I understand. I was lucky enough to be a great responder and after seeing the results on my PGD'ed embryos, I was shocked to see the number of abnormalities. I ended up with 2 normals. You can see in my siggy how many I started with. For the first time in my life, I really felt my age! Wishing you the best!
TTC 10/11. IUI 2/12. BFP 3/8/12. 4/26/12 missed mc. RE consult 5/17/12. IVF #1 ER 7/13/12 53R, 41M ICSIed, 32F, 8 5d, 6 6d blasts - all PGD/frozen. PGD results 1 normal M and 1 normal F, 1 maybe M. FET 9/6, transferred 1 F embie. Beta 9/15 BFN. FET#2 planned for 11/2012 put off until 2013. Surprise BFP 11/21/12!! My son was born on 7/24/13!
Hello! I guess I'm "young" here - 36yr ...trying for my first, we're still trying naturally, though it's been over two years (and longer since we stopped having protected sex)
I don't think I can be much help to you as far as information but I'm a firm believer that ANY chance is better than none... but I'm curious about the 15% chance of getting pregnant thing though - what I've heard is that even under the most ideal conditions, every cycle you only have a 20% chance of being pregnant anyway, in which case 15% doesn't seem SO bad... or is it 15% compared to something else?
[edited] sorry, I reread what I wrote and realized it turned into a long rant about me! So I just cut stuff out.
BFP with #1 (twins!) 11/18/2011 - missed m/c at 8weeks3days; d&c 1/19/2012; myomectomy to remove 18cm+,10cm & 5cm fibroids 4/2012; TTC again 7/2012; BFP #2 (twins) 11/13/2012; missed m/c at 7weeks;
BFP #3: baby girl born 3/5/2014
Balaustine: an anthology about wanting family