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Diagnostic testing?

mrsjamimrsjami member
in Multiples

So I'm disappointed that those new tests are not appropriate for twins (Materniti21, harmony, etc). Please tell me what testing you had done? With my last pg, my NT scan was perfect and didn't find out until end of 16 weeks that we had 1 in 9 chance of trisomy 18. We had scheduled an amnio, but beforehand during the u/s we found out the baby had passed away.  Needless to say, I definitely want to do testing, but scared of amnio or cvs for twins. Please share what you did.

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6/20/11 mc @ 5wks
10/19/11 mc @ 17wks- Trisomy 18
IUI #1 4/26/12 BFN
Moving on to IVF in July
37 with DOR...fabulous
ER 7/14/12 6R 5F, ET 7/17 3 embies, beta #1 7/26: 147, beta #2 7/28: 326, beta#3 7/30: 422...ugh, beta#4 7/31: 607...hopeful, beta #5 8/2: 1280, beta #6 8/7: 7184 and u/s shows 1 possibly 2 sacs! 8/14 2 beautiful heartbeats! 9/24 we are TEAM BLUE!!!!!
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Re: Diagnostic testing?

  • Sunglow28Sunglow28 member
    I had the maternit21 done with no problem. My genetic counselor told me that twins only decreased its efficacy by a point or two.
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  • mrsjamimrsjami member

    That's interesting! I called all the companies and Maternit21 is the only one that said you can use...but they have only studied it on 25 sets of twins. The good news is that it was 100% for those 25, but the sample size is too small to be conclusive. Regardless, I'm glad to hear you got good results!

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    6/20/11 mc @ 5wks
    10/19/11 mc @ 17wks- Trisomy 18
    IUI #1 4/26/12 BFN
    Moving on to IVF in July
    37 with DOR...fabulous
    ER 7/14/12 6R 5F, ET 7/17 3 embies, beta #1 7/26: 147, beta #2 7/28: 326, beta#3 7/30: 422...ugh, beta#4 7/31: 607...hopeful, beta #5 8/2: 1280, beta #6 8/7: 7184 and u/s shows 1 possibly 2 sacs! 8/14 2 beautiful heartbeats! 9/24 we are TEAM BLUE!!!!!
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  • bearfootzbearfootz member

    We did not do testing.  This was partially b/c dr. had asked if we'd terminate if there was an issue - if not, then it wasn't worth the risk/cost to do any testing.  He also stated that because we'd be seeing an MFM and having frequent u/s and 3d u/s's that we'd likely see ahead of time based on cranial measurements/etc. if there were a problem. 

    I don't know if this relates to your specific concerns, but this was our experience.

    *Siggy Warning*

    About me  2007: Started TTC. 2008: OB prescribed clomid, went to RE and was Dx with PCOS. 2009: IUI #1 w/follitsim and trigger = BFP. B/G Twins born at 33 weeks. 2012: TTC #3, Round 2 of Letrozole w/TI = BFP, missed m/c at 8 1/2 wks. Currently on the bench as we make plans for a new home. Anxious to start TTC #3 within the next year!

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  • Mrs.PawsMrs.Paws member
    I just spoke with the genetic counselor my OB referred me to and they have been using MaterniT21 as an option for women carrying twins.  I think my plan is to get that test done right around 10 weeks, wait for the results and then decide what, if anything, to do next. 
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