PGD results — The Bump
TTC after 35

PGD results

So, out of my 14 blasts, only two are normal with 95% confidence.  One M and one F.  There's one more M 75% confidence normal.  I'm kind of sad that I had that many abnormals.  Those two 95% represent my two chances.  I'm not sure yet if I will implant one or two, but leaning toward one at a time.  I'll probably choose not to implant the 75% confidence one.  But we'll see after I meet with the doctor.  
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TTC 10/11. IUI 2/12. BFP 3/8/12. 4/26/12 missed mc. RE consult 5/17/12. IVF #1 ER 7/13/12 53R, 41M ICSIed, 32F, 8 5d, 6 6d blasts - all PGD/frozen. PGD results 1 normal M and 1 normal F, 1 maybe M. FET 9/6, transferred 1 F embie. Beta 9/15 BFN. FET#2 planned for 11/2012 put off until 2013. Surprise BFP 11/21/12!! My son was born on 7/24/13!

FET 4/28/2015 - Transferred 1 M embie. 5/6/15 BFP!

Re: PGD results

  • I'm sorry I'm sure you were hoping for better news but overall I think this is still great and I'm incredibly hopeful for you.  Thank goodness you did pgd and now you know that you have at least two that are normal with almost complete certainty.  That is amazing!  Best of luck to you with whatever decision you make. 
    TTC since Dec. 2010. Me: 37, DH: 38...unexplained RPL
    BFP #1 - missed m/c 4.18.11 found @8w3d, d&c @13w 
    BFP #2 blighted ovum found 8.2011 @8w, misoprostol
    BFP#3 - missed m/c 6.11.12 @ 9w3d, d&c revealed extra chromosome 15
    BFP#4 8.10.12, DD born 4/26/13
  • First, congrats on the 2-3 normal blasts!

    Second, I'm sorry you only got 2-3 normal blasts out of 40 mature eggs. You would think that there would be more given they were already selected for by making it to blast. I guess it's true what they say about only 1 in 10 eggs being good at age 40. 

    Are the blasts frozen separately? I'd be tempted to transfer 1 at a time if you can afford the extra money if the 1st one doesn't take. 



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  • I'm sorry you didn't get better results it's hard to get so many eggs and do all the testing and wait for the results.  I'm happy you did receive two normal ones :) that's good news for you!!  I hope you don't mind me asking this question but why would you transfer only one of them and not both?  

    Me 38 MH 41 - TTC since June 2010 - dx with Severe MFI. Straight to IVF with ICSI. IVF #1 - ER 06/13/12 - 9 Eggs Retrieved - 4 ICSI'd - only 2 fert. 06/15/12 - 2DT - 3 cell & 6 cell with fragmentation. Beta 06/29/12 - IVF #1 = BFN. 07/20/12 - WTF Appt -Told by our RE to quit IVF. Second Opinion from RE is good. IVF#2 - November 2012. Estradiol Pills Started 11/6. Stims start 11/16. ER 11/26 - 7 eggs retrieved - all mature. 4 fertilized with ICSI. ET 11/29 Transferred 3 embryos. Beta is 12/10. 1st Beta 81 2nd Beta 160 and 3rd beta 360!!! First U/S 12/21/12 - We saw one beautiful gest. sac. 2nd U/S is 01/04/2013 - H/B 183 02/05/13 - NT Scan - everything looks good and IT'S A BOY!  Aiden was born 08/20/2013.

    IVF #2 is in progress.  ER was 05/12/14 - 11 eggs retrieved, 8 fertilized with ICSI.  ET was 05/15/14 - we transferred 3 embryos as we did on the cycle my son was conceived.  We were able to freeze 3 embryos. Beta is scheduled for 05/26/14.  1st beta - 111.  2nd beta - 159 didn't double :( 3rd beta Friday 5/30) - not a lot of hope left. Beta # 3 is 247 - probably ectopic.  Beta # 4 is 813 - possibly vanishing multiple sydrome?  06/05/14 - 5w4days - first U/S - we see a gestational sac and yolk - still have hope!  06/17/14 - 7w1day - U/S and saw and heard the heartbeat - Finally!  06/27/14 - 8w4days - Baby and heartbeat look and sound great :)  EDD 02/01/14 and It's a boy!


     "Everything will be okay in the end. If it's not okay, it's not the end."


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  • Sorry it wasn't what you were hoping for, but hopefully 2 is all you will need
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    [url=http://www.fertilityfriend.com/home/2aa3ac][img]http://www.fertilityfriend.com/home/2aa3ac/thumb.png[/img]
    My Ovulation Chart[/url]

    Missed M/C found Sept 2011 at 10 weeks.
    Took 2 doses of Cytotec.
    TTC again since Oct 2011.
    Endo BX and HSG April 2012
    found polyp in uterus
    Hysterscopy On May 4, 2012.
    Removed 2 polyps
  • Hoping those embryo's are your lucky #2s! Curious to hear what your Dr. has to say about the 75% one, maybe that's not all that bad?

    nate and teddy
    Me 41 DH 46  Not actively ttc, surprise BFP on 1/6/11! 4/1/11 m/c our sunshine at 16wks after complications from CVS test. TTC #2 **5th cycle 12/6/11 BFP! Missed m/c at 9 weeks 1/21/12, trisomy 14. Two Chemical PG 3/12&7/12
    ** BFP 8/16/12 beta #1 148! beta#2 407 beta #3 4000 u/s 9.10 1 lovely hb 126, Baby Boy is due 04/28/13!! Baby Birthday Ticker Ticker

  • emikatemikat member
    I am curious about the 75% one as well.  I am leaning toward doing one at a time, just in case the pregnancy doesn't take.  I'm not sure if putting both of them in at the same time will increase the risk of both failing if one doesn't take, etc.  I'll have to decide at the time of the appointment.  I do believe they are all frozen separately.  
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    TTC 10/11. IUI 2/12. BFP 3/8/12. 4/26/12 missed mc. RE consult 5/17/12. IVF #1 ER 7/13/12 53R, 41M ICSIed, 32F, 8 5d, 6 6d blasts - all PGD/frozen. PGD results 1 normal M and 1 normal F, 1 maybe M. FET 9/6, transferred 1 F embie. Beta 9/15 BFN. FET#2 planned for 11/2012 put off until 2013. Surprise BFP 11/21/12!! My son was born on 7/24/13!

    FET 4/28/2015 - Transferred 1 M embie. 5/6/15 BFP!

  • Sorry about the news you got but glad you have 2 healthy embryos. Good luck!!

    ME:46 MH:44 DE IVF 2014
    Met with RE 4/11. 2 IUI's BFN. DE best option. Switched clinics to do "shared" program. Had to retake all tests and a mamm that put me behind and then on a DE waiting list for 12 months. Picked a donor!! (10/13/13) Got matched. Estimated transfer in December. After 2.5 years of patiently waiting I will finally cycle....can hardly believe it. DE cycle got cancelled. One of her tests came back positive.  Waiting for another donor. Donor picked!! (1/18/14)

    DE IVF #1 (4/26) BFN  DE FET #1 (6/4) BFP! Beta 1=339 Beta 2=852 Beta 3=9957 EDD 2/22/15!!


     

     

         imageimage 
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  • I sorry it wasn't as many as you were hoping for. Keep us up to date and good luck with the 2 that you do have!
    Me: 38, PCOS/ DH: 37

    DD born 12.21.09, conceived w/ injects and IUI



    TTC#2 since Nov 2011

    BFP 2.6.12 m/c 6w5d | BFP 5.25.12 c/p

    -Back to the RE-

    3 medicated IUIs, all BFN

    -Taking a break from treatment-

    BFP 11.20.12 ~ EDD 7.28.13

    image image

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    My Chart
  • I am echoing pps-- one of each is great, and hopefully all you will need!

    I will keep everything crossed for you!

    *********************************************************************************************

    "You have to do your own growing no matter how tall your grandfather was." 
            -- Abraham Lincoln
     

                               Me:39  MH:39 
    DD born 6/1/2013 after 15 months of TTC with one loss.    
    TTC #2: BFP 4/22 but stalled growth and no HB at 9w3d on 5/30        

    <a href="http://www.fertilityfriend.com/home/3a2798" style="font-size:smaller;" >
    <br /> My Ovulation Chart</a>
  • Sorry there wasn't a higher number. Good luck with your little embies! 
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    Hx of PTL and GD, deliveries at 35 and 37 weeks. On P17 shots and modified bedrest now, a few scares but LO is hanging tough! !
    Three beautiful children; 17, 13, and 9, and very excited to be pregnant with DH first child after a tough year of TTC and fertility treatments.
  • I'm sorry you didn't get more normals, but 2 is still great and I hope that one of them will be your take home baby.

    Me:40 AMA, DH:36 0% morph, TTC#1;
    BFP#1 4/2011, MMC 6/2011 11wks Trisomy 13;
    BFP#2 11/2011, CP
    FSH: 17.9, AMH: 2.2
    IVF#1 w/ICSI: ER 4/3: 5R,4M,4F
    ET 4/6 All 4 (1-8A+, 2-8A-, 1-3A) BFP#3
    Two weeks of beta hell = Blighted Ovum
    IVF#2 Aug/Sept: ER 8/27: 4R,3M,3F
    ET 8/30 (1-8A+, 1-6A+)
    Beta#1 9/10: 350; Beta#2 9/12: 796; Beta#3 9/20: 9155
    Expecting Boy/Girl Twins! My babies were born 4/23/13 at 36w1d!

     
     

  • Try and focus on the good things - you have a few candidates :)  I didn't do PGD, but of my 30 retrieved, only 9 fertilized and only 4 were eligible for transfer.  Your decision on the # to implant is a very personal one - good luck with whatever you decide and my T + P are with you!
    Me-42 DH-43 TTC #1 since 3/11
    HSG 7/11 showed possible blockage
    8/11 BFP, then early m/c  (Natural)
    9/11 blood tests reveal Factor V Leiden (heterozygous)
    11/11 Hysteroscopy revealed uterine septum, which was repaired
    12/11 1st round of Clomid (100mg)=BFN
    1/12 2nd round of Clomid (100mg)=BFN 
    2/12 Repeat HSG=All clear 
    2/12 IUI with injectables #1=BFN 
    3/12 natural cycle=BFN 
    4/12 IUI with injectables #2=C/P 
    7/12 IVF #1=30ER, 9F, 3T, 1 Frostie 7/29=BFP! 
    8/27/12 No Heartbeat. Waiting to M/C 
    9/13/12 D+C
    12/12 Operative Hysteroscopy 
    1/31/12  IVF#2 ...BFP 2/6 m/c 2/12 methotrexate due to presumed ectopic
    July '13 IVF #3: 13R, 10M, 8F=BFP
    1st Beta=549  2nd Beta 594 3rd Beta 422. M/C #5
    IVF#4 in November=BFP…TWINS!!!!!

    BabyFruit Ticker
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