We met with our RE yesterday to get the genetics results on our embies and to schedule our FET. The results were very interesting. Of the 3 that were abnormal, 2 of them were the best quality of the bunch. They were the highest grade possible, grew at the perfect rate, and overall looked "perfect". They were absolutely the 2 that we would have transfered if we had done a fresh transfer without the genetic testing!!
one of them had 3 extra chromosomes, and the other had 1 missing chromosome. The third that was abnormal had a mutation on the long arm of chromosome 7 (whatever the heck that means).
I feel like we just dodged a bullet. Just goes to show that the "perfect" embies may not be so perfect after all.
So of the 4 that we have that are genetically normal, 1 is the highest quality grading, 2 are good quality, and the other 1 is fair/good quality. We still don't know the sex of the embies and we are going to keep it that way until they stick around. So we are going to transfer 2 (the grade 1 and the grade 2 embies) on September 26th!!!
Re: Kind of crazy update
::: Married June 2003:::

TTC #1 since: Aug. 2008
Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
Tx History: IUI 1&2= BFN
IVF# 1 W/ICSI= BFN
IVF# 2: cancelled d/t no response
IVF# 3= 1 egg retrieved=immature/not viable
IVF# 4= c/p
***CCRM ODWU***
Found DHs BT and Me-decreased blood flow to uterus
Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
***New RE***
DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture.
IVF# 6: (OE/DS) cancelled
IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015
http://icanhazbabyz.blogspot.com/
TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
5 IUI's: 2/11 to 6/11 and 1/12= BFN
OE IVF#1-4 8/11-6/12= all BFN
DE IVF#1 11/12 bad embryos= BFN
DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
DE IVF #3 1/14 ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d
DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!
K & K born 11/21/14 at 38wks 4 days
SAIF/PAIF Welcome
http://waitingforraintostop.wordpress.com
Wow, what interesting results. Of my abnormals, you could clearly see that they were abnormal when you looked at them, even for laymen like me. I am so so happy that you have some great normal embies and I would recommend to everyone to not know the sexes as that can make it harder if things don't work out. GL for Sept 26th!!!'
Multiple ectopics, 2 failed IVF's
IVF #1: Did not get to ET, embies all failed PGD (major chromosomal defects)
IVF #2: We have 2 chromosomally perfect embies as a result of PGD (Boy/Girl) 1 failed the thaw (Girl) Transferred 1, yet ended as a c/p
Thought it was the end of our TTC Journey 6/20/2012
SHOCK BFP 9/28/2012: IT'S A BOY! and everything is normal !!!!!!
Little A born 38w 2d on 05/23/13 and is a true miracle for this IF Vet!
Me: 36, DH: 42
Dx: DOR and MFI
DH: low count + very low motility; hormones all normal; Sperm DNA Frag. test = poor to fair; male karyotyping normal
Me: FSH 13.4 + AMH 0.26 + hypothyroidism; Scratch the hypothyrodism (?); Blood clotting and immune panel all negative; endometrial biopsy normal
IVF #1 (MDLF - Jul/Aug 2011): BFN (9R, 5M, 3F with ICSI, 3dt of 1 10-cell grade 2, no frosties)
IVF #2 (EP-antagonist - Sep/Oct 2011): BFN (6R, 4M, 3F w/ ICSI, 3dt of 1 6-cell, 1 7-cell, grade 4s, no frosties)
DE IVF #1 (shared cycle - June 2012): c/p (6R, 6F w/ICSI, 3dt 1 8-cell grade A- and 1 7-cell grade A-; no frosties)
DE IVF #2 (shared cycle with new donor - Nov/Dec/ 2012): - BFP!!!!! 12/14/12. U/S on 12/27 shows twins!!!!!
SAIFW/PAIFW
SOunds like you have some great embies to put back sweets, and I agree with you re: the 'dodged a bullet' quote. Perfect looking definitely does not mean perfect genetically.
GL on the 26th!
Me: 39, Dx DOR (FSH = 10.5, AMH = 0.43, best AFC = 10), AMA
MH: 37, Dx Obstructive Azoospermia, multiple successful sperm retrieval procedures
2/2012: IVF/ICSI #2 MDLF (4R, 4M, 1F) = BFP, saw heartbeat, missed m/c 9w0d, D&E
8/2012: IVF/ICSI #3 EPP/MDLF (7R, 2M, 1F) = BFN
12/2012: (New RE) Operative hysteroscopy to remove scar tissue
1/2013: IVF/ICSI #4 Low-dose stim/Antagonist (AFC=6); ER=1/26 (5R-couldn't access rt ovary, 5M, 4F), ET=1/29 (trans 3) = BFP!; 2/11 beta#1(13dp3dt)=2127, 2/13=3367; twin girls due 10/19/13
PAIF/SAIF very welcome!
<a href="http://www.thebump.com/?utm_source=ticker&utm_medium=HTML&utm_campaign=tickers" title="Pregnancy"><img src="http://global.thebump.com/tickers/tt16bf7d.aspx" alt=" BabyFruit Ticker" border="0" /></a>
Totally agree that good looking embryos does not always equal genetically normal. We did two rounds of PGD for a specific diagnosis (DH's balanced translocation) and we had so many (per RE) "high quality textbook embryos" yet the one and only "normal" embryo in the bunch was of poor quality. RE said we make beautiful embryos...too bad we can't use them.
Best of luck with your FET!! That's awesome you have 4 to work with!
"Now faith is being sure of what we hope for and certain of what we do not see." Hebrews 11:1
DX: 6/9/2011: Azoo ICSI/IVF only option for biological child
IVF #1: ER - 9/26 * ET - 10/1 * beta#1 10/13 - 140 * beta#2 10/17 - 477 * beta#3 10/20 - 1101
1st u/s at 6w6d - one hb * 2nd u/s at 8w3d - no hb detected 11/10/11 * natural m/c 11/13/11
FET #1 Jan/Feb 2012 - 3 delays - cancelled 2/13
FET #1.2 - May/June 2012 - ET 6/6/* beta#1 6/15 - 95 * beta #2 6/19 - 322 * beta #3 6/22 - 940
7/6 1st u/s @ 7 weeks - one beautiful hb - released from RE
EDD 2/22/2013
PAIF/SAIF/PGAL welcome
After 1 IUI, 3 IVF's with CGH/CCS testing, 10 early miscarriages, and lots of tears and frustration, we are moving on to Domestic Infant Adoption! We are so excited to see what the future holds.
That is super interesting! It just goes to show you that less than perfect embies can make beautiful babies!
Good luck with your FET!
TTC since 5/2010
DX with Diminished Ovarian Reserve - AMH of 1.1 - 7/2011; AMH of .42 8/2012BFP 9/1/10-M/C confirmed 9/8/10-Methotrexate 10/6/10
IUI #1 (w/clomid)-9/5/11-BFN ; IUI #2 (w/clomid)-10/5/11 - BFP - 11/1/12-No sac seen; 11/2/11 and 11/9/11-Methotrexate
IVF #1- ER 2/2; ET 2/5;-Two 8 cell embryos transfered = BFFN
Surprise BFP - 5/7/12
U/S on 6/8/12 - H/B at 128 BPM; U/S on 6/14/12 @ 9wks-No H/B-D&C on 6/17/12
IVF 2.0- ER 10/17; ET 10/20-One 12 cell, one 10 cell and one 8 cell embryo transfered
BFP! 11/16/12 U/S- Two nuggets with perfect heartbeats! EDD 7/10/13
5/31/2013- My miracles arrived at 34w2d! Welcome to the world Harper and Nolan!

My Blog- http://waitingonaangel.wordpress.com/
TTC since March 2009 // Me and DH - 28
Testing Summer/Fall 2010 - Unexplained IF
IUIs #1-4 ~ Clomid/Ovidrel/TI/IUI ~ all BFNs
IUI #5 ~ Femara/Ovidrel/TI/IUI ~ BFN
IUIs #6-9 ~ Research Study Meds/Pregnyl/TI/IUI ~ all BFNs
IVF Consultation, More Testing
Diagnostic Cycle ~ Mucinex/Progesterone/TI ~ BFN
IVF #1 ~ Menopur/Bravelle/Ganirelix/Novarel/Progesterone/Lupron
7R, 6F // 2 transferred // 3 frosties ~ BFN
FET #1 ~ Estrace/PIO/Lupron
3 thawed // 2 transferred // 1 lost // no more frosties ~ BFP!!
Beta #1 - 456 // Beta #2 - 1176 // Beta #3 - 2933 // Beta #4 - 6753
EDD: May 16, 2013
Bedrest for SCH // 6w2d through 10w1d
Elevated TSH and Lazy Thyroid DX @ 10w - Started Synthroid
Finally released from RE at 13w
~~ My IF Blog ~~
TTC since 2007
6 IUIs, 3 IVFs, and 2 m/c :< PCOS, Blood Clotting Disorder & MFI
IVF #2 Aug 2011 is a BFN:<
IVF #3 March 2012 is a BFN
Not sure what to do now. Sad and lost.
IVF #1-July 2011 7/9/11-Started Stims
7/20/11-ER:No eggs in 4/5 follicles. Left the 5th follie intact and converted to an IUI
8/3/11-Beta #1=BFN,
Nov, 2011 BFP #1=m/c at 7 wks 3 days
11/11-AMH .47, IVF #2 March 2012...or not!! Surprise BFP on 2/19. Beta #1=161. Beta #2 305 Our little miracle girl is on her way! Due Oct 29, 2012
<a href="http://s1207.photobucket.com/albums/bb461/andersenspics/?action=view
Me: 32 - Stage II Endo / DH: 36 - Low count and morphology (1%)
IUIs 1-3 BFN, lap Dec. 2010, IUIs 4-6 BFN
IVF w/ICSI #1 - ER 2/8: 24R 19M 9F ET 2/13 2-5 day blasts (no frosties) = BFP - b/g twins!
E & C Born 10/19/2012
TTC #1 since 3/10:
DX: Me-PCOS, retroverted/ tilted ute - DH- MFI, DH-4 mo of Clomid therapy= no improvement. Weekly HCG injections.
Me-34, DH-33
HSG- unsuccessful, SHSG (dialated)-no blockages
7/11-Clomid (unmonitored) BFN,
#1 Fresh IVF 9/11: w/ ICSI & AH (only option): (1 transfered, 8BF) = BFN!!
#2 FET: 2 transferred (2 6BF) 12/11 = BFFN!!
Surprise + HPT on break! 2/12 Beta 1: 6 Beta 2: <5 = c/p ( RE had given me provera... So pretty sure this ruined everything)<BR> #3 Fresh IVF 3/12: w/ ICSI & AH (2 transfered 8BF & 7BF, 1 to freeze) = BFMFN!
New RE 5/12
6/14 Hysteroscopy
#4 Fresh IVF 8/12: 5dt of 2 5AB blasts = BFN!... what else is new?!?
New RE insists its a transfer issue, immunology checked & good
#5 IVF FET 1/13 under anesthesia : Two 5 day blasts transferred
+ HPT!! Beta1: 2315 Beta2: 6442 Beta3: 31,061
First u/s 1/30/13: Shows 1 healthy heartbeat!!
Was he was right? I wasted 4 IVF's and the doctors were not getting the catheter in?!?
~~ Bump Bestie/ IRL Lynn0926 ~~
~ticker warning~
Wow! That is crazy! I am glad you dodged a bullet. Praying these are your sticky guys! You ET is on my 3rd anni, so it has to work. It is a great day ??
DH: Severe MFI/Azoo Me: Compound heterozygous MTHFR
IVF #1= m/c- methotrexate @6w2d
FET #1= BFN
IVF #2= m/c- D&C @8w5d
IVF #3= Beta #1 9dp5dt= 252, Beta #2 11dp5dt= 417, Beta #3 17dp5dt= 4,952
US #2 @ 7w2d= twins, baby B measuring behind
US #3 @ 8w5d= Baby A doing well, no HR in baby B
*S/PAIF always welcome*
Positive for HLA-B27, I'm a mutant
Testing - Me ok, gluten issue? DH - borderline count, low motility
4/28/11 IUI#1 = BFP!(5/25), EDD 2/2/12 - m/c 5w3d
7/3, 7/31, 9/25 - IUI#2-4=BFN
IVF#1 - 1 blast = BFP!! (12/30), EDD 9/9/12, confirmed c/p 4w2d
FET#1 3/2/12 - 2 blasts =BFP!! EDD 11/18/12, us#1 = twins! Confirmed m/c 5w6d
4/20-surprise BFP and another c/p 4w2d
FET#2 7/16/12 - 2 blasts = BFN
FET#3 8/20/12 - 1 blast - BFP!! Beta #1-2=177, 354
1st u/s 5w6d, one beautiful little HB
baby girl born 5/10/13
TTC#2 since 12/17/2014, Cycle 8
Repeat Testing...FSH=12, AMH=3.8, AFC=28.
IUI#5 5/10/15- c/p?
IVF#2 8/19/15 - cancelled due to cysts
IVF#2 take two 10/2015 - 5 blasts frozen
FET#4 12/11/2015 - BFN - 4 blasts remaining
FET#5 2/18/16 - BFP!!! Beta1-3, 126, 250, 745!!
Tons of love and ((hugs)) to my IF sister NMscubagirl
Wow! That really makes you think!
Wishing you lots of luck!
TTC since 2008 dx PCOS & MFI
Clomid/Femara no "O"
IVF #1 BFN
FET #1 cancelled for biopsy
FET #1.2 c/p, July 2012 c/p
IUI #1 & 1.2 canceled
IVF #2 ER 12/1, Freeze all due to OHSS
FET #2.1 cancelled due to DVT risk, FET #2.2 Jan 2013
my blog
Hysteroscopy 3/2011 2 Polyps removed 4/2011
DH on Clomid / Arimidex to address hormonal issues - Sperm found July 2011!
IVF #1 September 2011 - ER 9/8/2011- 8R, 5M - icsi - 1 made it to transfer - BFFN :-(
IVF #2 Lucky November 2011 - ER 11/25/2011 - 15 eggs!, 13 mature, 10 fertilized with isci - 7 made it to transfer! Transferred 1 - 8 cell and 2 - 7 cell. BFP!!!!
1st U/S - Twins! 2nd U/S - 3 heartbeats!!! - HOLY COW!!!
Prayers for our take home babies!
2 babies born on 3/27/12 and lost. Last baby born on 3/29/12 and lost at 20 weeks.
My angels grew wings shortly after birth.
Ahava Raisel, Matisyahu Nissim & Zev Chaim - Mommy and Daddy will always love you.
IVF #3 July 2012 - ER 7/17/2012 - 10 R. 5 F. 4 made it to ET
Transferred 2 on 7/20/2012 no snow babies :-(
Beta on 7/31/2012 = BFMFN
A miracle gift expected to come to us through adoption around 9/2012
Baby girl adopted - Birth Mother changed her mind and took the baby back
IVF #4 October 2012 - New RE. Doing PGD Testing. 8 R, 7F, 2 made it to 5 day blast for PDG testing. Both Normal (Thank you G-d!!!) 1 boy and 1 girl
transferred one beautiful 5day blast (girl)
Please G-d the almighty one - let this be our take home baby!
Beta #1 158, Beta #2 318, 1 Absolutely magnificent HB at 175! Thank you G-d!!!
Baby Girl born August 5th. Thank you G-d for our precious miracle.
AMA. PAIF & SAIF always welcome - I need all the prayers I can get!
3/22 ER: 25R, 20M, 15F. 9 genetically normal, and 3 survived to Day 5
3/27 ET: transferred 1 embryo, beta 9dp5dt=163, 12dp5dt=639
4/25 1st ultrasound at 7 weeks = identical twins with heartbeats?!!!