Ugh? so frustrated. Not sure if you recall my latest story. Dh started taking clomid 6-7 weeks ago. We planned to do IVF 5 in July, but decided to push it back to Sept to give the meds time. The MFI uro said we couldn?t repeat SA for 3 months. Dh had bloodwork on Fri 7/6 to test testosterone and other hormone levels. We finally got the results of that today. The nurse said testosterone went up to 8.08 which is good. (I don?t recall number before clomid.) However, nurse said dh?s Estradiol/estrogen is higher than we would like, which is bad. (She didn?t give me the Estradiol number.) She said this means extra testosterone is being converted and stored as estrogen. Thus, we need to block this conversion from happening. Therefore, they prescribed a new prescription of Anastrazole (generic for Arimidex) for dh to take with the clomid. Dh needs to have bloodwork again in 4 weeks to see if the Estradiol is where it should be.
I asked the nurse about the SA since we had to wait 3 months and I thought it was 3 months from starting clomid. She said no, it is 3 months from when we get Dh?s hormone levels where we want them. If the Estradiol is good in 4 weeks, then nurse said we can use today as the start date of the 3 month window. Otherwise, if it is not good, then they will need to tweak the meds or something and who knows how long that will take.
IVF 4 in Feb was a bust since we had ER but didn?t make it to ET. At that time, dh and I agreed to try IVF again and if it worked, I would continue be a SAHW/M. Otherwise, we agreed I had to look for a new job before we could afford to try IVF 6. We figured cycling would be easier if I wasn?t working, especially if I got a new job that it would be hard to justify wanting time off right away. DH was busy at work in April & May, so we planned to do IVF 5 in July, which we pushed back when dh started seeing the new MFI uro and they put him on clomid per above.
Now, I don?t know what to do. I need to talk to dh, but am interested in your opinions. Do we continue to wait to see if the clomid & new med helps dh, do the repeat SA in 3 months and cycle after that. We are hoping the SA improves, but what if it doesn?t?! If SA doesn?t improve, we will do IVF anyway, which would now be Oct-Nov at the earliest with the 3 month wait for SA situation. If SA improves dramatically, we may consider IUI or TI. I hate to spend the money on IVF if we don?t have to. However, we have the money and I?m sick of waiting. I feel guilty being home without kids and not having a job and I feel like it keeps getting pushed back further. Should we do IVF asap (which would probably be Sept at this point anyway since I?m mid-cycle now and they want me on BCP beforehand) and just hope it works since he doesn?t really need good count or morph for IVF with ICSI? Then, if IVF doesn?t work, dh will still be on the meds and we can try on our own while I look for a job and maybe find one.
Sorry this is so long. Feeling sad and frustrated today.
Re: WWIFVD? (long)
Hey Sweetie. I would have to say wait (I know easier said than done). DH was also put on Clomid and the same thing happened. He was put on Arimidex and when they found sperm I thought we were home free. We were told by the uro to wait another couple of months after that but we were so eager we just couldn't. Well needless to say that IVF was a bust - we only had one egg fertilize. The drs said the sperm would get stronger and better - and it did.
I know waiting is so hard. Good luck. I wish this was easier on all of us.
Hysteroscopy 3/2011 2 Polyps removed 4/2011
DH on Clomid / Arimidex to address hormonal issues - Sperm found July 2011!
IVF #1 September 2011 - ER 9/8/2011- 8R, 5M - icsi - 1 made it to transfer - BFFN :-(
IVF #2 Lucky November 2011 - ER 11/25/2011 - 15 eggs!, 13 mature, 10 fertilized with isci - 7 made it to transfer! Transferred 1 - 8 cell and 2 - 7 cell. BFP!!!!
1st U/S - Twins! 2nd U/S - 3 heartbeats!!! - HOLY COW!!!
Prayers for our take home babies!
2 babies born on 3/27/12 and lost. Last baby born on 3/29/12 and lost at 20 weeks.
My angels grew wings shortly after birth.
Ahava Raisel, Matisyahu Nissim & Zev Chaim - Mommy and Daddy will always love you.
IVF #3 July 2012 - ER 7/17/2012 - 10 R. 5 F. 4 made it to ET
Transferred 2 on 7/20/2012 no snow babies :-(
Beta on 7/31/2012 = BFMFN
A miracle gift expected to come to us through adoption around 9/2012
Baby girl adopted - Birth Mother changed her mind and took the baby back
IVF #4 October 2012 - New RE. Doing PGD Testing. 8 R, 7F, 2 made it to 5 day blast for PDG testing. Both Normal (Thank you G-d!!!) 1 boy and 1 girl
transferred one beautiful 5day blast (girl)
Please G-d the almighty one - let this be our take home baby!
Beta #1 158, Beta #2 318, 1 Absolutely magnificent HB at 175! Thank you G-d!!!
Baby Girl born August 5th. Thank you G-d for our precious miracle.
AMA. PAIF & SAIF always welcome - I need all the prayers I can get!
Me: 36, DH: 42
Dx: DOR and MFI
DH: low count + very low motility; hormones all normal; Sperm DNA Frag. test = poor to fair; male karyotyping normal
Me: FSH 13.4 + AMH 0.26 + hypothyroidism; Scratch the hypothyrodism (?); Blood clotting and immune panel all negative; endometrial biopsy normal
IVF #1 (MDLF - Jul/Aug 2011): BFN (9R, 5M, 3F with ICSI, 3dt of 1 10-cell grade 2, no frosties)
IVF #2 (EP-antagonist - Sep/Oct 2011): BFN (6R, 4M, 3F w/ ICSI, 3dt of 1 6-cell, 1 7-cell, grade 4s, no frosties)
DE IVF #1 (shared cycle - June 2012): c/p (6R, 6F w/ICSI, 3dt 1 8-cell grade A- and 1 7-cell grade A-; no frosties)
DE IVF #2 (shared cycle with new donor - Nov/Dec/ 2012): - BFP!!!!! 12/14/12. U/S on 12/27 shows twins!!!!!
SAIFW/PAIFW
Positive for HLA-B27, I'm a mutant
Testing - Me ok, gluten issue? DH - borderline count, low motility
4/28/11 IUI#1 = BFP!(5/25), EDD 2/2/12 - m/c 5w3d
7/3, 7/31, 9/25 - IUI#2-4=BFN
IVF#1 - 1 blast = BFP!! (12/30), EDD 9/9/12, confirmed c/p 4w2d
FET#1 3/2/12 - 2 blasts =BFP!! EDD 11/18/12, us#1 = twins! Confirmed m/c 5w6d
4/20-surprise BFP and another c/p 4w2d
FET#2 7/16/12 - 2 blasts = BFN
FET#3 8/20/12 - 1 blast - BFP!! Beta #1-2=177, 354
1st u/s 5w6d, one beautiful little HB
baby girl born 5/10/13
TTC#2 since 12/17/2014, Cycle 8
Repeat Testing...FSH=12, AMH=3.8, AFC=28.
IUI#5 5/10/15- c/p?
IVF#2 8/19/15 - cancelled due to cysts
IVF#2 take two 10/2015 - 5 blasts frozen
FET#4 12/11/2015 - BFN - 4 blasts remaining
FET#5 2/18/16 - BFP!!! Beta1-3, 126, 250, 745!!
Tons of love and ((hugs)) to my IF sister NMscubagirl
Baby boy Henry born 2015.
Expecting our capstone baby (boy) early March 2018.
This exactly. Big big (((hugs)))
TTC since 2008 dx PCOS & MFI
Clomid/Femara no "O"
IVF #1 BFN
FET #1 cancelled for biopsy
FET #1.2 c/p, July 2012 c/p
IUI #1 & 1.2 canceled
IVF #2 ER 12/1, Freeze all due to OHSS
FET #2.1 cancelled due to DVT risk, FET #2.2 Jan 2013
my blog
I know very little about this, so take what I say with a grain of salt, but a few thoughts --
1) I know 3 months is ideal to see if there is an improvement and probably before 3 mos. it is hard to say much of anything if there isn't an improvement, but would it be possible to do a S/A monthly just to see what's going on? That way if there is an improvement before 3 months you could presumably cycle sooner.
2) Does your RE think DH's MFI has played a factor in your failed IVFs? If it's neither here nor there and the hiccups seem to be more in your response, then I think that gives some support to just proceeding along with IVF sooner rather than later. If the RE/DH's uro think that an improvement in DH's sperm could increase your chances of a successful IVF outcome in a big way, that would definitely support waiting to see if the Clomid will help.
To simplify the decision-making I might take the possibility of IUI/TI out of the equation..it would be amazing if that becomes an option, but I think it will be really disappointing if holding on to that possibility is the only thing encouraging you to wait and then it doesn't pan out.
GL, illingal - thinking of you guys!
IVF #1 = BFN
FET #1 = BFN
FET #2 = BFN
IVF #2 = BFP, b/g twins lost at 20w due to partial abruption/PPROM
IVF #3 = c/p 5w2d
Long-shot Clomid/Prednisone cycle before next IVF = BFP, our beautiful, healthy girl born 6/26/13!
~~
TTC again March 2014
FET #3 - May/June 2014 - all embryos arrested before xfer - back to the drawing board...
IVF #4 - July/August 2014
I know it is hard but I would wait too...
3 failed IVF with OE and 2 failed frozen DE cycles
Last fresh hail mary DE cycle starting Feb 2013
PAIF/SAIF always welcome
I agree here, would you have any interest in a low-key p/t job? Good luck to you...
I'm so sorry that you are having to plan whether or not to get a job dependent on your IVF success and/or sperm sucess. That sounds very stressful and I honestly feel like you and your hubby probably know what it best based on your own financial situation. Although I will say, I got a new job earlier this year and it has really improved my mood. So I think your emotional well-being should be a factor as well. Like you said- you don't feel good about being at home without kids. I kind of feel that way too when I get home from work to an empty house. I feel like kids should be there, it can be very depressing.
As far as the sperm factor goes. I agree with you that clomid therapy is a much longer process than advertised! We were given the 3 month line too. It took 5 months just to get DH's testosterone up after several dose changes. His sperm count hasn't improved yet, but when we tested it, it was right after his hormones were where we wanted them at. So we are retesting this week actually to see if there is any improvement. We decided that we will cycle no matter what in September (at that point, it will have been about 8 months of clomid). We also just added arimidex last week too. Also, our new uro actually wants to try a TESE this time since we have not had success yet with ejaculated sperm. We may fertilize half eggs with TESE sperm and half with ejaculate. This is still kind of up in the air, but is currently what we are discussing. I'm up for trying anything at this point.
Good luck with whatever you decide to do!
DH: Severe MFI/Azoo Me: Compound heterozygous MTHFR
IVF #1= m/c- methotrexate @6w2d
FET #1= BFN
IVF #2= m/c- D&C @8w5d
IVF #3= Beta #1 9dp5dt= 252, Beta #2 11dp5dt= 417, Beta #3 17dp5dt= 4,952
US #2 @ 7w2d= twins, baby B measuring behind
US #3 @ 8w5d= Baby A doing well, no HR in baby B
*S/PAIF always welcome*
Moving forward with Adoption 2017!