Infertility Veterans

Clomid with EPP Antagonist?

So my RE just called.  Slight change of plans.  I'm starting Clomid for 5 days on Thursday night, adding Follistim on Saturday night & coming back in for an u/s & b/w on Tuesday.  She told me to bring the Ganirelix with me Tuesday too.  Clomid wasn't originally part of our plan but because of low E2 she's adding it.  Anyone have any experience with this?  I've heard of it in the literature (rarely) but have never "met" (online forums) anyone who's done it.
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Re: Clomid with EPP Antagonist?

  • mm29mm29 member
    I do not have experience with this protocol, but I think jackie2200 was on it. It brought her, her bfp. GL!
    ::: Married June 2003:::
    TTC #1 since: Aug. 2008
    Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
    DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
    Tx History: IUI 1&2= BFN
    IVF# 1 W/ICSI= BFN
    IVF# 2: cancelled d/t no response
    IVF# 3= 1 egg retrieved=immature/not viable
    IVF# 4= c/p
    ***CCRM ODWU***
    Found DHs BT and Me-decreased blood flow to uterus
    Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
    ***New RE***
    DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture. 
    IVF# 6: (OE/DS) cancelled
    IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
    Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015


    http://icanhazbabyz.blogspot.com/
    imageimage image 
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  • for one of my IUI the RE discussed using the Clomid with an injectable. I guess he decided against using this approach since "we" did not do it that way. If I recall I think he was going to use it because it allowed a slow rise of the follicles.

    What ever works would be fine and dandy with me!

    TTC since 2009 very frustrated 42yr and DH 40

    5 cycles of Clomid with satisfactory response=BFN's
    Fibroid removal Nov2010
    IUI Clomid #1 Feb 2011...BFN..damn it!
    IUI Inject's #2 Apr 2011...CANCELLED...low estradiol
    IUI Inject's #3 June 2011...BFN
    IUI Inject's #4 Sept2011...BFFN
    Lap Dec 2011...severe endo..cyst removed..some remains...
    IVF#1 Apr 2012 ....cancelled due to over suppression
    IVF#2 July 2012....6 follies...only 1 retrieved....BFFN
    surgery suggested to move ovary to an better placement but....we moved two time zones away and are financially and emotionally empty

  • No help here except to say that if we had cycled a final time, it would have been testosterone priming which includes clomid during stims.  When I researched it, I found almost nothing of use. 
    Baby girl Lila born 2013.
    Baby boy Henry born 2015.
    Expecting our capstone baby (boy) early March 2018.
  • Km672Km672 member
    I did this protocol last winter. It was my 4th unsuccessful IVF, but we got the most eggs. Be prepared, I stimmed for longer and it took longer to see the results 

    Me (32) DOR, elevated NK Cells/ 2 copies of MTHFR mutation/ MH (35) azoo/high DFI   (TTC#1 since 2009)

    IVFs#1-4: (4/10-2/12) all BFN

    Surprise Bfp (9/11) - c/p

    DS IUI#1-2 (9/12, 10/12) - BFN

    DS IVF: (11/12) - BFN

    DE/DS IVF#1: (10/13) - 2 day 3 embies transferred-BFFN

    FET of 2 day 6 blasts: (12/13) - c/p

    DE/DS IVF #2: (4/14) - 1 day 5 blast transferred...BFFN...again.

    FET 5/14: 1 day 5 hatching blast transferred...another BFFN

    Repeat SHG 6/14-normal / Endometrial Receptivity Array biopsy 7/14-Receptive Uterus

    New RE, additional testing reveals elevated NK Cells

    FET of 1 day 5 blast (RE recommends transferring 1 due to elevated NK cells) with lovenox, steroids & intralipids in October

     

     

     

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