Zofran, how do I love thee... — The Bump
Pregnant after IF

Zofran, how do I love thee...

I have been having the worst m/s; nauseous all the time, throwing up several times a day.  Last week I started taking Unisom + B6, and that definitely helped--it cut out most of the nausea.  But I still had a serious gag reflex, and would still throw up. 

Yesterday I saw my RE and he said I was borderline for needing Zofran, and not to be afraid to ask for it.  I heard him, but thought--I can do this!  Yeah, right.  After not holding anything down the rest of the day, DH said enough is enough--and I called and got the prescription.  Started feeling better 45 minutes later, and was FINALLY able to eat!  The awful acid feeling through my esophagus is gone this morning, and there's no gag reflex whatsoever!  

I don't feel 100% normal; and food still tastes funny.  But I can eat and function again--hooray!

TTC #1 Since 8/2010
Me: 34, DH: 35 DX: DOR (FSH 14.9, AMH 0.67, AFC ~10) and Egg Quality

IVF #1 Feb 2012. MDFL protocol w/ Met. 7 ER, 0F.
May Donor Egg IVF cycle:3 EF, 1 blast ET 5/12, 2 frosties
BFP 5/21! beta #1 5/22 306 beta #2 5/24 818 beta #3 5/31 15,038.

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"Expecting the world to treat you fairly because you are a good person is a little like expecting the bull not to attack you because you are a vegetarian." --Dennis Wholey

Re: Zofran, how do I love thee...

  • So glad you are starting to feel better and are able to enjoy food a little more.
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    TTC since April 09

    SA 4% morph ~ RE recommends IVF

    DH diagnosed with Varicocele ~ surgery Sept 2010

    DH results came back good! Jan 2011 ~ Recommend IUI

    IUI#1,2 & 3 ~ clomid = BFN

    IUI#4 7/26 ~ 5mg Femara = BFN

    IUI#5 8/22 ~ 150iu Bravelle + HCG + Booster = BFP!!!!

    9/27 @ 7weeks pg no h/b & enlarged yok sac (m/c)

    IUI#6 12/12 ~ 100mg clomid = BFN

    IUI#7 1/11 ~ 150iu Bravelle + HCG + Booster = BFFN

    IUI#8 2/8 ~ 225iu Bravelle + Ovidrel + Prometrium = BFP!!!

    6w3d ~ hb 126 8w3d ~ hb 160, March 30th~ Released from RE

    A/S June 15th ~ It's a BOY!

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  • Just got my prescription yesterday! :)
    PCOS 
    Off bcp March 2011 
    Aug 2011-Feb 2012 tried to regulate cycles w/ Metformin -- no luck 
    April 2012: Clomid (50mg) + Injects + TI = BFN
    May 2012: Clomid (100mg) + Injects + TI = BFP on 6/8/12   

    Lilypie - (74ba)
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  • Glad you're feeling better.
    Me: 35 DH: 37 TTC since 4/2010
    DX: 6/9/2011: Azoo ICSI/IVF only option for biological child
    IVF #1: ER - 9/26 * ET - 10/1 * beta#1 10/13 - 140 * beta#2 10/17 - 477 * beta#3 10/20 - 1101
    1st u/s at 6w6d - one hb * 2nd u/s at 8w3d - no hb detected 11/10/11 * natural m/c 11/13/11
    FET #1 Jan/Feb 2012 - 3 delays - cancelled 2/13
    FET #1.2 - May/June 2012 - ET 6/6/* beta#1 6/15 - 95 * beta #2 6/19 - 322 * beta #3 6/22 - 940
    7/6 1st u/s @ 7 weeks - one beautiful hb - released from RE
    EDD 2/22/2013
    PAIF/SAIF/PGAL welcome
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  • TJ1979TJ1979
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    I'm glad you're feeling better!
    TTC with PCOS since November 2009
    IUI#1 Femara/Ovidrel (cd 3-7) = BFP, m/c
    IUI#2 Femara/Ovidrel (cd 5-9) = BFN
    IUI#3 Femara/Ovidrel (cd 3-7) = BFP!
    beta #1 11/23 = 270, P4 = 75
    beta #2 11/28 = 2055
    Our daughter E was born 7/29/2012!
    Surprise, our 2nd daughter P was born 5/22/14!
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  • I love my Zofran! I do have to take Colace pretty often though, so you may need it too. Glad you can eat again! 
    Lilypie Angel and Memorial tickers
    IVF #1 BFP b/g twins!; loss at 23 weeks due to I.C. and PTL. IVF #2 BFP 5/26/12; due date 2/6/13; TAC surgery 7/20/12, blessed with another girl & boy! 

    Lilypie Second Birthday tickers
  • My sis totally prepared me for what to have on hand when I got pg. I had the unisom sleep tabs, b6 and zofran ready as soon as we got the + hpt. I have only had to take zofran 2 times, but keep it with me at all times. LOVE IT. 

    How often do you take unisom + b6? I take 1/2 tab at night with my prenatal that has b6 in it. 

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    Left Tubal Ligation in 2004
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    1.16.12 LAP due to Ectopic @ 7w, Right Tubal Ligation
    3.19.12 IVF #1 - Stims (Lupron + Gonal F + Luveris)
    3.29 ER - 6 snowbabies (ET postponed due to OHSS)
    FET 6/6 - transferred two 4AB snowbabies
    Beta #1 6/16 = 683, Beta #2 6/18 = 1703, Beta #3 6/20 = 4073, u/s #1 @ 5wks = TWINS!!, 7w u/s two heartbeats <3 <3 TWIN BOYS<br>

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  • Zofran was the only thing that moderately worked for me during pregnancy.  I took it everyday until I gave birth.  Glad it's working for you.
    Me: 27, DH: 28 TTC since 11/09
    2/10 & 3/10 Clomid 50mg-BFN
    5/10-Lap Surgery for Stage 2 Endo
    3/11-IUI#1 with Follistim and Menopur-developed mild OHSS= BFN
    6/11-IUI#2 with Follistim -developed moderate OHSS= BFN!
    7/11-FSH-11, AMH 1.6
    9/11-ttc naturally with positive thoughts :)
    10/6/11-POSITIVE pregnancy test!!! 15dpo BETA-220
    6/14/2012- Riley Harper arrived!! We love our little girl
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  • So glad you feel better! My OB is a total sadist and refused to give it to me despite me throwing up 3x/day. 
    TTC in 2009, Dx: Unexplained IF
    Three TI cycles (BFP...miscarriage), five IUI attempts and 2.5 IVF cycles later...BFP!!
    12dp5dt: 765; 15dp5dt: 1979; 17dp5dt: 3379...TWINS!!!!!
    Our perfect baby boys were born at 36w1d!! 








  • Zofran is a Godsend! Just be warned - it can cause horrible constipation. I had to stop taking it because I was unable to go to the bathroom for days!! (Sorry if that was TMI :)
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    TTC for 5+ years
    2/09 - TI = BFP * 3/09 - M/C with D&C * 8/09 - C/P
    Jan - July '10 - Clomid/Follistim + IUI = all BFN
    Aug - IVF #1 - 3 embies transferred = BFN
    Mar - IVF #2 - 2 embies transferred & 4 frosties = BFN
    June - FET #1 * 2 embies transferred = BFP (C/P @ 5w4d)
    Sept - FET #2 * 2 embies transferred = BFP
    Nov - M/C & D&C at 10 weeks
    May - surprise BFP with no medical intervention
    Sept - 20 week US showed we're having a BOY!
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  • sekurasekura
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    image cindyc24:

    My sis totally prepared me for what to have on hand when I got pg. I had the unisom sleep tabs, b6 and zofran ready as soon as we got the + hpt. I have only had to take zofran 2 times, but keep it with me at all times. LOVE IT. 

    How often do you take unisom + b6? I take 1/2 tab at night with my prenatal that has b6 in it. 

    Before I went on the Zofran, I was taking 1/2 a Unisom at night with 25mg B6, and a whole Unisom in the morning (with 25mg B6).  Now that I'm taking Zofran, I take it at 5:30 am and about 2 pm, then 1/2 a Unisom and the B6 before bed.

    Thanks for the warnings about constipation, ladies!  I knew it would be an issue, and have upped my fiber intake already.  But I think I'll need to take a colace tonight.

    TTC #1 Since 8/2010
    Me: 34, DH: 35 DX: DOR (FSH 14.9, AMH 0.67, AFC ~10) and Egg Quality

    IVF #1 Feb 2012. MDFL protocol w/ Met. 7 ER, 0F.
    May Donor Egg IVF cycle:3 EF, 1 blast ET 5/12, 2 frosties
    BFP 5/21! beta #1 5/22 306 beta #2 5/24 818 beta #3 5/31 15,038.

    image"">
    Baby Birthday Ticker Ticker
    "Expecting the world to treat you fairly because you are a good person is a little like expecting the bull not to attack you because you are a vegetarian." --Dennis Wholey

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