Pregnant after IF
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IVF girls: What grade were your embryos?
I'm just curious to see what type of embryos result in a pregnancy. If you got pregnant via IVF, how many times did you try and what grading did your embryo(s) have? Thanks!
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Re: IVF girls: What grade were your embryos?
IVF #1: 1 grade aa day 5 blast (my clinic's perfect grade)...negative
IVF #2: 1 Grade bb day 5 blast was upgraded to ab within minutes of transfer (went from "fair" to "good") and 1 day 5 early blast (so slow it couldn't even be graded)...pregnant with twins!
12dp5dt: 765; 15dp5dt: 1979; 17dp5dt: 3379...TWINS!!!!!
Our perfect baby boys were born at 36w1d!!
DX: High FSH/DOR
It took 44 cycles, just over 3 years, 6 failed IUI's in MI, and 1 round of IVF at CCRM to get our BFP!
Beta #1 (9dp5dt) = 206, Beta #2 (11dp5dt) = 438
1st u/s @ 6w5d = 11/11/11 = ONE little bean! HB 120bpm!
?Our Baby Boy Born June 26th, 2012?
IUI#3 - Jan 6 IVF#1 -5/18 - stims start (225 gonal f, 75 menopur, 5 lupron) ER 5/29 - 14R, 11M, 7F. 6/1 - Transferred 2 8cell embryos (grade 1 and 2). 8dp3dt +HPT, Beta#1 - 92, Beta #2 - 174, Beta#3 - 614, Beta#4 - 2010. 6wk u/s - TWINS! Baby A 114bpm, Baby B 112 bpm
Me-36, Unexplained Infertility, DH-35, all clear
Clomid 50mg 12/2011 = BFN
Clomid 100mg 1/2012 = BFN, with Cyst
IVF #1 Lupron/Menopur/Gonal-f/HCG Trigger
ER 4/19/12 = 11 retrieved, 6 fertilized,
ET 4/22/12 = 2 transfered (day 3), remaining 3 weren't good enough to freeze
Beta 5/3 = BFP, 87 Beta #2 5/7 560.9 Beta #3 5/9 1376.5 First u/s One Baby, 125bpm!
Second u/s, 176bmp! Kicked over to the OB by the RE at 8w. Team Green!!
I think that these questions are why my embryologist would not give our embryos grades at our transfer. Because you can't always judge how they will do by just looking at them. She just said to us on our day 3 transfer which one she thought was the best looking one and why, in non-quantitative terms-- it is not growing too fast or two slow, it is beginning to compact, and doesn't have that much fragmentation. I still don't think it was all the pretty looking in the photo they gave us compared to some I have seen of other people's, but it stuck. So you just never know. I know people who have had slow poke morulas on day 5 turn into healthy babies, too.
I tried IVF once and transferred one 3d compacting 10ish cell embryo.
IVF #1 ET 1 d3 embryo 10/30/11 BFP
3 Embryos frozen (1 d5, 2 d6)
DS born 07/29/12
FET #1 ET 1 d5 embryo 02/10/15 BFN
FET #2 1 d6 embryo didn't survive thaw, transferred last d6. CP
I can't remember exactlly but....
IVF 1: all arressted but 2 and they were very poor grade
IVF 2: all arressted but 3 and they were a hair better then IVF 1
IVF 3: we changed and did a 3 day instead of 5dt; Grades are in my siggy and I'm pg with twins.
After loads of my own research I found that if there are quality issues before day 3 then that's sperm, if there are quality issues after day 3 that's egg issues. If it's egg issues then you should consider 3dt. I begged and begged for this from my RE for IVF3, basically forcing her hand the night before. Everything always looked stellar for us for the first 2-3 days, then wham they'd all arrest and or be really poor quality. If we ever go back for a 3rd baby I will only entertain a 3dt of 1high quality embryo. Hope this helps
#1 - transferred one early blast and one morula, one stuck but I m/c
#2 - transferred one beautiful blast, one early blast, and one morula, one stuck and divided
IVF 1 April 2011 - Cancelled
IVF 1.5 July 2011 - MC
IVF 2 October 2011 - BFP!
*Identical Twin Boys born June 2012*
Here we go again...IVF 3 is underway!
IVF #1 - 8 cell A and 9 cell A = negative
FET - 2 8 cell A = negative
IVF # 2- 2 day 5 morulas = negative
IVF # 3- 2 8 cell with no fragmentation =positive
3 IUI's w/Clomid & Ovidrel=all BFNs
3 IVF (2 Fresh, 1 frozen) =BFN
Jan 2012 New RE & Fresh Cycle =BFP!
IVF #1- 2 "beautiful" blasts= c/p
FET # 1- 3 beautiful blasts= twin m/c
IVF # 2 messed up ganirelix dose (due to RN mistake)-terrible 2 day transfer
IVF # 3- 2 decent blasts=BFN
IVF # 4= 1st day 3 transfer with assisted hatching. one 7 cell grade 1, one 8 cell grade 1 (RE said grade 1 was the best) and a 10 cell grade 3= bfp & twin pregnancy!
Wedding Fall 2007 Off OCP's since 9/08-started with BBT charts Saw Ob/gyn May 2009 Blood work normal except single copy of MTHFR Clomid 50mg May 2009 Clomid 50mg + IUI June 2009 Femara 5mg + IUI July 2009 Normal HSG July 2009 Femara 5mg + ovidrel+IUI August 2009 Femara 5mg +ovidrel + IUI September 2009 November 2009-normal lap December 2009-met with RE December/January-Injectible med cycle with IUI-Abnormal sperm morpology found-only 0-1% normal All Head defects. Jan/Feb 2010 1st IVF with ICSI-5 week chemical pregnancy
Feb 2010-male infertility doc says DH's anatomy and blood work are normal so nothing he can do. 
FET July 2010-BFP! Twin m/c @ 5.5 wks 
Dec/Jan 2011 IVF #2 Only 4 eggs retrieved-Ganirelix dose messed up BFFN
Feb/March 2011 IVF #3 ER 3/9 9 eggs, 7 fertilized, ET 3/14, No frosties. BFN
IVF #4 ER 8/22 9R,7F ET 8/25-3 embies, 1 frostie! Beta 9/2= 54, 9/6=274, 9/8=625, 9/12=2953, 9/16 greater than 10,000. B/G TWINS born April 2012 @ 36wks & 1 day!
July 2014-going back for the frozen embryo! ET 7/28, heartbeat seen at 6wks1day with SCH. Miscarriage confirmed at 6wks4days
TTC #1 Since 8/2010
Me: 34, DH: 35 DX: DOR (FSH 14.9, AMH 0.67, AFC ~10) and Egg Quality
IVF #1 Feb 2012. MDFL protocol w/ Met. 7 ER, 0F.
May Donor Egg IVF cycle:3 EF, 1 blast ET 5/12, 2 frosties
BFP 5/21! beta #1 5/22 306 beta #2 5/24 818 beta #3 5/31 15,038.
"Expecting the world to treat you fairly because you are a good person is a little like expecting the bull not to attack you because you are a vegetarian." --Dennis Wholey
IVF #1: 3dt so grades vary wildly. We transferred 3:
1 x 7 cell grade B. 1 x 7 cell grade C and fragmented. 1x 5 cell grade C and fragmented
We are just guessing that the 7 cell grade B is the one that made - the other two were highly criticized by our embryologist.
#1 BFP 1/10/11; missed m/c discovered 7w5d
IF Dx: Endo, hetero MTHFR mutation, poor morphology
#1 IUI: 1/18/12 = BFN
#1 IVF/ICSI 4/2/12 = 2 x 7-cell and 1 x 5-cell transferred (3dt) = BFP!!
H was born at 41w2d on 12/29/12 - be still my heart!
#2 IVF/ICSI 1/19/14 = 2 x 8 cells transferred (3dt) = BFP!! EDD 10/09/14
M&W born at 37 weeks on 9/18/14 - I am the momma of 3 boys!!!
To be honest, I don't think there's a "type" of embryo that results in a pregnancy, while there are other "types" that do not. I think it's a bad idea to over-analyze embryo grades. It can psyche you out unnecessarily.
That said, I did spend massive amounts of time over-analyzing embryo grades over the course of 3 fresh IVF cycles, so here are my stats:
At my clinic 1 = early blast and 5 = expanded blast; A = highest grade and D = lowest grade. I always did 5-day transfers.
IVF #1: transferred (1) 2BB- blast and (1) 1BC blast. Nothing to freeze. Did not get pregnant.
IVF #2: transferred (2) 2CC blasts and (1) OK-looking morula. Nothing to freeze. Did not get pregnant.
IVF#3: transferred (1) 1BB blast, (1) 1BC blast and (1) 1CC blast. The 1BC blast had been a 1CD blast an hour before the transfer. We wound up with (1) embryo to freeze on day 6 (a 6BB), and on day 5 that embryo had been a 1CD blast. I am pregnant with one baby.
Hope that helps!
Me = lean PCOS;DH = poor morphology (3%)
3 IUI/TI cycles = BFN
IVF #1 with ICSI: antagonist protocol = BFFN
IVF #2 with ICSI : Lupron downregulation = BFFN...FML
IVF #3 with ICSI and AH (Antagonist) = IT'S A BOY!!!!
We only did IVF once.
We got 5 eggs but only one made it to a 3 day transfer. That one was a grade B, 4 cell, fair. I am now pregnant with that one egg :-)
As far as I know the grading is only based on the "appearance" of the embryos. Our clinic didn't really give us a grade but our Dr. said it was a "very good looking blastocyst" on day 5. On day 3 we still had 10 growing so that was why they pushed us out to day 5.
This was our first IVF, we transferred one on day 5 and are pregnant with one baby.
When I was going crazy researching stuff I found this website quite helpful:
https://www.advancedfertility.com/blastocystimages.htm
There is a lot of info on both day 3 and day 5 embryo grading, just keep in mind your clinic might not use the same system this clinic does.
Good Luck!!
"I prayed for this child and the Lord has granted what I asked of him." ~1 Samuel 1:27
"Whatever it takes, we walk together." ~Pittsburgh Penguins
My IF-turned-baby blog
We had 1 embryo on day 3 that was graded a 2. Our clinic grades day 3 transfers on a 1-5 scale 1 being the highest.
As other have said you have to take the embryo grading with a grain of salt because so many people have success with so many different grades. Also keep in mind it can be hard to distinguish what we say and compare it to what your clinic grades because each clinic grads their embryo's differently.
Married 09.9.11 (Me:31 and DH:31)
TWIN BOYS<br>
Left Tubal Ligation in 2004
1.2.12 BFP
1.16.12 LAP due to Ectopic @ 7w, Right Tubal Ligation
3.19.12 IVF #1 - Stims (Lupron + Gonal F + Luveris)
3.29 ER - 6 snowbabies (ET postponed due to OHSS)
FET 6/6 - transferred two 4AB snowbabies
Beta #1 6/16 = 683, Beta #2 6/18 = 1703, Beta #3 6/20 = 4073, u/s #1 @ 5wks = TWINS!!, 7w u/s two heartbeats
***SAIFW & PAIFW***