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TTC After a Loss
LSzwaya
member
MTHFR ladies...
LSzwaya
member
What are you doing as your treatment if you have a MTHFR mutation? I am heterozygous for the C677T and my doctor kind of made it seem like if I take extra folic acid, which I did already, that it wouldn't be an issue. But I keep reading about Folgard and prescription strength folic acid via google. Am I Dr. Googling myself crazy or should I be pushing for a different protocol than just regular folic acid?
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Re: MTHFR ladies...
I am compound hetero for both strains. My first pregnancy I took 4mg folic acid and baby aspirin daily. My 2nd pregnancy we did the same because we didn't know at the time that I really had something going on. Supposedly, that is normal protocol and it is usually enough.
Going forward, our new plan will be Folgord starting 3 months prior to us TTC and then I'll be on a blood thinner too. I believe they are looking at Lenovox (sp). My only problem now is that they can't decide when I should start it. My RE and OB want to start as soon as a pregnancy is confirmed. My MFM doesn't want to start until we have a heartbeat.
If you are concerned, maybe you should get a second opinion??? I wanted blood thinners for my last pregnancy, but they refused and I didn't fight hard enough.
Our baby boy,Logan, was born still at 19w3d on 7/1/2011
Our 2nd baby boy, Mason, was born still at 20w3d on 1/31/2012
After a much needed sanity break... we are praying for our rainbows
((BFP 7/29/13)) ((EDD 4/12/14)) It's BOY/GIRL twins!!!
I'm compound heterozygous as well. My doctor said extra Folic Acid, B6 and B12 which is I'm pretty sure exactly what Folgard is in one pill. I take L-methylfolate personally (also whats in Folgard I think). Its the already broken down form of Folic Acid since people with MTHFR typically can't process FA into something usable. I get it from Life Extension (www.lef.org).
I don't take baby aspirin or any other blood thinners. My RE believes that since my homocysteine levels were normal that I'm not at risk of blood clots. Asking for a homocysteine check might be worthwhile.
Good luck!
[spoiler] My Blog: Grow Baby Grow
BFP #1: 12/2009 m/c 1/2010 BFP #2: 6/2010 m/c 8/2010
BFP #3: 10/2011 ectopic 11/2011 (right tube removed, learned left tube was probably nonfunctional due to scar tissue from infection after m/c)
3 failed IUIs, IVF #1: 18R, 12M, 10F, 3 poor quality 5d embryos transferred= BFP #4!!!!!
Betas: 9dp5dt: 64 ~14dp5dt: 91 (expecting miscarriage, doubling time of 236 hours) ~16dp5dt: 200~18dp5dt: 500
First Ultrasound at 6w2d revealed two sacs, only one with a heartbeat
LK arrived after 42 weeks on August 14, 2013! Beautiful, healthy, and happy!
TTC#2: IVF booked for April 2015
Surprise BFP#5 February 19, 2015 EDD: November 2, 2015
Betas: 10dpo: 10, 14dpo: 77, 17dpo: 270
First Ultrasound at 5w1d showed a miracle UTE baby! And right ovary ovulation to left fallopian tube.
JD arrived at 38 weeks on October 20, 2015.
TTC #3: Since October 2017. BFP #6 July 2, 2018 EDD: March 16, 2019 [/spoiler]
Thanks!
My homocysteine levels were fine, I believe. I am going to be on the blood thinners for other issues.
My homocysteine levels were normal too.
Our baby boy,Logan, was born still at 19w3d on 7/1/2011
Our 2nd baby boy, Mason, was born still at 20w3d on 1/31/2012
After a much needed sanity break... we are praying for our rainbows
((BFP 7/29/13)) ((EDD 4/12/14)) It's BOY/GIRL twins!!!
Laura,
Folgard does not contain L-methylfolate. It contains synthetic folic acid. What you are taking is perfect for women with the MTHFR mutation as well as everyone else. LSzwaya, you might want to ask your doctor about L-methylfolate. Women with the MTHFR mutation cannot properly metabolize synthetic folic acid. Active L-methylfolate bypasses the MTHFR polymorphism and is 100% bioavailable for DNA synthesis and repair. I know you have a less severe form of the mutation but you cannot be certain you are getting the folate you need when you are taking synthetic folic acid. Particularly with your history, it is something simple and safe you could do to be sure folate deficiency is not contributing to your losses.