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May2806

damabo80damabo80 member
in Infertility Veterans

Siggy warning

 

 

 

I hope you don't mind me responding. This is regarding the metanx.  Most likely the RE put you on it for the c667t homo MTHFR. It's a high dose b vitamin/folic acid that is already in its broken down form to allow for easier absorption. With that particular variant of MTHFR, your body has a hard time breaking down regular folic acid to its usable form. My son had a fatal NTD, and my RE attributes this to the MTHFR (I have two copies of c667t as well). I started taking metanx after that pg and after the MTHFR was discovered. Thankfully, no other NTDs to date. I take it for three months before starting a cycle, and continue it throughout pregnancy. 

Ive been to two RE clinics over the years, and both were in agreement for lovenox throughout pg as well since that MTHFR is a higher risk for clots.  

Anyways, hope you don't mind me chiming in (I stalk worms on occasion); I hope this answered your question. 


BFP #1 via IUI ~ L (Fatal Birth Defect) 4/7/10
BFP #2 via IUI ~ m/c
BFP #3 via cancelled IUI ~ C (2lb 3oz; HELLP) 5/16/11
BFP #4 via the natural (free!) way ~ E (8lb 11oz) 9/13/12
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Re: May2806

  • may2806may2806 member
    I don't mind you responding - thanks for the info. I did speak with the doctor and this is the same thing he said. I have already been on Folgard for a long time but he said this is a "newer, better" version. I'm also nervous about the lovenox because I had a lot of bleeding in my last pregnancy (that is why I lost my daughter). But Worms assures me Dr B knows what he is doing!
    Dx: High FSH, stage IV endo, homozygous C677T MTHFR and PAI-1
    Early loss 10/08
    Lap 1/09
    IVF #1 "natural IVF" - 1 egg retrieved, missed m/c
    Tried several mini-stim cycles with no response
    Switched clinics - dx'd as carrier for Fragile X
    IVF #2 MDL protocol Jan/Feb converted to IUI, BFN
    IVF #2 take 2: Antagonist, one embie, BFN
    IVF #3: Antagonist, no fertilization
    One last ditch effort at OE IVF (antagonist with Clomid) cancelled
    DE cycle #1 Jan/Feb 2011, BFP, ectopic
    DE cycle #2 June/July 2011 - BFP
    10/28/11 Baby girl lost at 17 weeks due to pre-term labor. We love and miss you.
    DE cycle #3 June/July 2012 - BFP, twins, both heartbeats stopped, D&C
    2 frosties but don't know what's next
    FET Dec 2012: BFP! Praying this one sticks for the long haul!
    Report Reply
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  • may2806may2806 member
    Also I am very sorry for the loss of your son. But congrats on your daughter and latest pregnancy!
    Dx: High FSH, stage IV endo, homozygous C677T MTHFR and PAI-1
    Early loss 10/08
    Lap 1/09
    IVF #1 "natural IVF" - 1 egg retrieved, missed m/c
    Tried several mini-stim cycles with no response
    Switched clinics - dx'd as carrier for Fragile X
    IVF #2 MDL protocol Jan/Feb converted to IUI, BFN
    IVF #2 take 2: Antagonist, one embie, BFN
    IVF #3: Antagonist, no fertilization
    One last ditch effort at OE IVF (antagonist with Clomid) cancelled
    DE cycle #1 Jan/Feb 2011, BFP, ectopic
    DE cycle #2 June/July 2011 - BFP
    10/28/11 Baby girl lost at 17 weeks due to pre-term labor. We love and miss you.
    DE cycle #3 June/July 2012 - BFP, twins, both heartbeats stopped, D&C
    2 frosties but don't know what's next
    FET Dec 2012: BFP! Praying this one sticks for the long haul!
    Report Reply
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