I also registered at Springfield, it was nice, and staff was good. Be sure to check there is a nice coupon for a free $10 giftcard when you register (didn't offer when I went). Happy shopping!
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I can't say with any authority since we did all of our registry stuff through Amazon, but wouldn't the BRU website offer the best selection? If you need to see stuff in person, whichever is most convenient should be fine. If they don't carry or can't order in something you want from another store, take that as a sign that they don't really want your business.
Re: Which Babies R Us is best to register?