Infertility Veterans

visiting from IF board: empty follicle syndrome

anyone have any experience with this? Out of 30 plus follies only 14 eggs were retrieved? Doc said the rest were empty! Freaking out here, that is not normal!

 

My Blog

Me:26 PCOS, IR, MTHFR c677t/c677t, arcuate uterus DH:27 4% morphology
11/2006 Married My DH
Started trying on Honeymoon
2009/2009 4 failed clomid cycles, many BFN, PCOS Study
4/2010 5 rounds of femara resulted in BFP!
6/2010 Lost our little poppy.
7/2010 DX: MTHFR C677t/C677t
2/23/2011 Starting first IUI cycle. Follistim and ovidrel. Fingers crossed...
First IUI=BFN Second IUI=BFN
9/2011: IUI 3,4,5,6 BFN
1/2012 New year New plan... First consult for IVF.
4/3/2012 First day of our 1st IVF cycle..
5/16 ER 14R 6M 5F (25+ empty follicles)
5/19 ET 3dt of 2 grade A 8 cell embabies!!! Stick baby stick
8dp3dt BFP! Beta#1 12dp3dt 136, #2 14dpt 336, #3 16dpt 845
6/19/2012 7w HB 131!!! 6/27/2012 8w HB 173
Baby Delaney is scheduled to be induced Jan 30, 2013!!

imageimageimageLilypie Pregnancy tickers

Re: visiting from IF board: empty follicle syndrome

  • We had this issue too.  For IVF #1 I had about a dozen follies @ 15+ plus a few others that were 12-15 & may have caught up by the time of ER.  We only got 5 eggs.  I had previously done 8 IUIs & none of them worked; it may very well have looked like I had 2-3 "mature" follies but they were empty so I never even had a chance.  For IVF #2 we'll be adding LH & maybe some other stuff to help mature my eggs since of the 5 we only ended up with 1 embryo.  My RE also told me to add CoQ10 in case there's a quality issue.  FWIW I was 32 for IVF #1 & just turned 33 last month so I'm not AMA & nothing indicates DOR either.

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  • I had this too with IVF#4.  It's heart breaking.  They thought we would get 4 eggs becasue I had what looked like 4 mature follicles on u/s but they only got 1 egg.  It nearly killed us to get such terrible news.  However, we won the IVF lottery because I'm being induced with that one egg at 9pm tonight. 

    I stimmed for 21 days on 4 vials of Bravelle and 2 vials of menopur.  I've never been a good responder but I'm sure my eggs were fried from the inside out becasue I had never stimmed for that long before. Could that have happened to you? 

    I'm sorry that you have to go through with this but I hope you get lucky too. 


    TTC Since 10/08 4 IUIs=BFNx4
    IVF#1=BFP!! Twins!!
    Bradley and Billy born and lost on 2/2/11 at 19w2d due to pPROM/PTL. I miss you, little angels.
    IVF#2=BFN
    IVF#3=c/p IVF#4=Empty Follicle Syndrome; 1 mature, fertilized, & made it to blast. 5dt of "the lone ranger" on 9/6. Please stick, little one! Image and video hosting by TinyPic Lilypie First Birthday tickers
  • I wouldn't be freaking out. You got 14 eggs. What more can you ask you for! That is an excellent number. Try coming out of ER with no eggs. That is empty follicle syndrome.
    Pregnancy Ticker
  • mm29mm29 member
    imagelynn0926:
    I wouldn't be freaking out. You got 14 eggs. What more can you ask you for! That is an excellent number. Try coming out of ER with no eggs. That is empty follicle syndrome.
    I agree with Lynn. I think 14 eggs is something to be proud of. although I have never experienced empty follicle syndrome, in my best cycle I have only had two eggs retrieved. GL!
    ::: Married June 2003:::
    TTC #1 since: Aug. 2008
    Me: 34, DOR, MTHFR-A1298C (heterozygous), decreased blood flow to uterus, Mild Endo
    DH: 38, Balanced translocation 5&10, unexplained MFI, normal SA and SCSA
    Tx History: IUI 1&2= BFN
    IVF# 1 W/ICSI= BFN
    IVF# 2: cancelled d/t no response
    IVF# 3= 1 egg retrieved=immature/not viable
    IVF# 4= c/p
    ***CCRM ODWU***
    Found DHs BT and Me-decreased blood flow to uterus
    Recommended DE IVF w/PGD, incorporate electro-acupuncture. Decided to cycle locally
    ***New RE***
    DE IVF# 1(cycle #6) w/pgd, (freeze all): 30R, 23M, 15F, slow/poor embryo development, 4 biopsied, 1 Normal "Norm"; DE IVF w/PGD, incorporate electro-acupuncture. 
    IVF# 6: (OE/DS) cancelled
    IVF# 7: (OE/DS) 1R, 1M, 1F, arrested day 5
    Plan-DE IVF# 2 (cycle #8): DE/DS in May 2015


    http://icanhazbabyz.blogspot.com/
    imageimage image 
  • I am not upset with 14 eggs, I mean I know that it could have been much less. What worries me is that more than 50% of my follicles were empty. I went in with 35 follicles 18 of which were mature 2 days ago. That just totally scared me that we only got less than 1/2 which is when they call it empty follicle syndrome. Now im worried maybe something is wrong with my eggs? Thank you for your support, I in no way wanted to offend anyone. It was just hard news to take when you expect so much more. I guess thats the IF bandwagon though. Thoughts are prayers to you all.
    My Blog

    Me:26 PCOS, IR, MTHFR c677t/c677t, arcuate uterus DH:27 4% morphology
    11/2006 Married My DH
    Started trying on Honeymoon
    2009/2009 4 failed clomid cycles, many BFN, PCOS Study
    4/2010 5 rounds of femara resulted in BFP!
    6/2010 Lost our little poppy.
    7/2010 DX: MTHFR C677t/C677t
    2/23/2011 Starting first IUI cycle. Follistim and ovidrel. Fingers crossed...
    First IUI=BFN Second IUI=BFN
    9/2011: IUI 3,4,5,6 BFN
    1/2012 New year New plan... First consult for IVF.
    4/3/2012 First day of our 1st IVF cycle..
    5/16 ER 14R 6M 5F (25+ empty follicles)
    5/19 ET 3dt of 2 grade A 8 cell embabies!!! Stick baby stick
    8dp3dt BFP! Beta#1 12dp3dt 136, #2 14dpt 336, #3 16dpt 845
    6/19/2012 7w HB 131!!! 6/27/2012 8w HB 173
    Baby Delaney is scheduled to be induced Jan 30, 2013!!

    imageimageimageLilypie Pregnancy tickers
  • pinkmickey was having similar issues, except I think she had 0/30ish.  She's over on TTTC and IF as well.  ((hugs))  Hopefully one of your 14 will work out!
    TTC #1 Since 4/2010, Cycle 30
    Positive for HLA-B27, I'm a mutant :p
    Testing - Me ok, gluten issue? DH - borderline count, low motility
    4/28/11 IUI#1 = BFP!(5/25), EDD 2/2/12 - m/c 5w3d
    7/3, 7/31, 9/25 - IUI#2-4=BFN
    IVF#1 - 1 blast = BFP!! (12/30), EDD 9/9/12, confirmed c/p 4w2d
    FET#1 3/2/12 - 2 blasts =BFP!! EDD 11/18/12, us#1 = twins! Confirmed m/c 5w6d
    4/20-surprise BFP and another c/p 4w2d
    FET#2 7/16/12 - 2 blasts = BFN
    FET#3 8/20/12 - 1 blast - BFP!! Beta #1-2=177, 354
    1st u/s 5w6d, one beautiful little HB :), 2nd u/s 146bpm
    baby girl born 5/10/13

    TTC#2 since 12/17/2014, Cycle 8
    Repeat Testing...FSH=12, AMH=3.8, AFC=28. 
    IUI#5 5/10/15- c/p?
    IVF#2 8/19/15 - cancelled due to cysts
    IVF#2 take two 10/2015 - 5 blasts frozen
    FET#4 12/11/2015 - BFN - 4 blasts remaining
    FET#5 2/18/16 - BFP!!!  Beta1-3, 126, 250, 745!!

    Image and video hosting by TinyPicLilypie Angel and Memorial tickers

    Tons of love and ((hugs)) to my IF sister NMscubagirl


  • Thank you all for your advice, Im still really confused at what has happened with this ivf, yet I cant find answers online anywhere. Of the 14 retrieved only 6 were mature and 5 fertilized. 

    when you start with 35 follies, and 20 some large enough to be mature, this just isnt what you expect to happen.

    IF always has to show whos in charge, thats for sure.

    anyone else have so many immature eggs? reasons why? I stimmed for only 8 days. 

    My Blog

    Me:26 PCOS, IR, MTHFR c677t/c677t, arcuate uterus DH:27 4% morphology
    11/2006 Married My DH
    Started trying on Honeymoon
    2009/2009 4 failed clomid cycles, many BFN, PCOS Study
    4/2010 5 rounds of femara resulted in BFP!
    6/2010 Lost our little poppy.
    7/2010 DX: MTHFR C677t/C677t
    2/23/2011 Starting first IUI cycle. Follistim and ovidrel. Fingers crossed...
    First IUI=BFN Second IUI=BFN
    9/2011: IUI 3,4,5,6 BFN
    1/2012 New year New plan... First consult for IVF.
    4/3/2012 First day of our 1st IVF cycle..
    5/16 ER 14R 6M 5F (25+ empty follicles)
    5/19 ET 3dt of 2 grade A 8 cell embabies!!! Stick baby stick
    8dp3dt BFP! Beta#1 12dp3dt 136, #2 14dpt 336, #3 16dpt 845
    6/19/2012 7w HB 131!!! 6/27/2012 8w HB 173
    Baby Delaney is scheduled to be induced Jan 30, 2013!!

    imageimageimageLilypie Pregnancy tickers
  • I always have 40 follies and only get 4-7 eggs....I would be psyched with 14.  GL!
    Anniversary
    TTC #1 since 3/10:
    DX: Me-PCOS, retroverted/ tilted ute - DH- MFI, DH-4 mo of Clomid therapy= no improvement. Weekly HCG injections.
    Me-34, DH-33
    HSG- unsuccessful, SHSG (dialated)-no blockages
    7/11-Clomid (unmonitored) BFN,
    #1 Fresh IVF 9/11: w/ ICSI & AH (only option): (1 transfered, 8BF) = BFN!!
    #2 FET: 2 transferred (2 6BF) 12/11 = BFFN!!
    Surprise + HPT on break! 2/12 Beta 1: 6 Beta 2: <5 = c/p ( RE had given me provera... So pretty sure this ruined everything)<BR> #3 Fresh IVF 3/12: w/ ICSI & AH (2 transfered 8BF & 7BF, 1 to freeze) = BFMFN!
    New RE 5/12
    6/14 Hysteroscopy
    #4 Fresh IVF 8/12: 5dt of 2 5AB blasts = BFN!... what else is new?!?
    New RE insists its a transfer issue, immunology checked & good
    #5 IVF FET 1/13 under anesthesia : Two 5 day blasts transferred
    + HPT!! Beta1: 2315 Beta2: 6442 Beta3: 31,061
    First u/s 1/30/13: Shows 1 healthy heartbeat!!

    Was he was right? I wasted 4 IVF's and the doctors were not getting the catheter in?!?
    ~~ Bump Bestie/ IRL Lynn0926 ~~
    BabyFruit Ticker
  • I had the same thing. On the first cycle I had 10 follicles but only 5 were eggs and out of 14 follicles only 7 were retrieved on the second cycle.  I felt like such a failure and my RE had no real explanation as to why it happened.
    Pursing Domestic Infant Adoption through a local agency. In the meantime, our dog is our baby.  Bumping from Portland, Oregon. 
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