I did an antagonist protocol...started with estrogen pills for 2 weeks then went in to follistim/menopur...then added ganirelex...then Ovidrel before the ER. They did this with me because I have DOR and don't start out with a ton of follicles (usually around 10 total)...the antagonist protocol is a more aggressive treatment and used with ladies they think might be poor responders. From what I understand if you have PCOS or are at risk for hyper-stimulation than they wouldn't do this protocol.
The final type of protocol is known as the antagonist protocol. In this treatment, a medication other than Lupron is used to supress the pituitary gland and prevent ovulation. This newer type of medication is called a GNRH antagonist. There are two brands of this medication: Ganarelix and Cetrotide. These medications do not have a flare effect. In fact, the supression of the pituitary gland is almost immediate. This is a big advantage since the IVF specialist can start the medication after the ovaries have been stimulated instead of a two week pre-treatment period as is seen with the Lupron. This makes the antagonist IVF protocol much shorter than the Lupron protocol.
I have pcos and did this protocol....works,so far!
After years of struggling with infertility issues (PCOS since I was 16) and 15 medicated cycles we finally got blessed with our son. We got lucky with our 7th IUI using stims...Now we are back on the roller coaster to try for another miracle..IVF cycle in May resulted in a chemical pregnancy. 2 snowbabies FET 7/16-transferred 2 blastocyst...Faint bfp 4dp5dt!
Re: Antagonist Protocol - newbie question
I did an antagonist protocol with ivf. Here is some good info for you.
https://www.advancedfertility.com/ivf-stimulation-antagonist.htm
I did an antagonist protocol...started with estrogen pills for 2 weeks then went in to follistim/menopur...then added ganirelex...then Ovidrel before the ER. They did this with me because I have DOR and don't start out with a ton of follicles (usually around 10 total)...the antagonist protocol is a more aggressive treatment and used with ladies they think might be poor responders. From what I understand if you have PCOS or are at risk for hyper-stimulation than they wouldn't do this protocol.
Below is from www.ivfspecialist.net
The final type of protocol is known as the antagonist protocol. In this treatment, a medication other than Lupron is used to supress the pituitary gland and prevent ovulation. This newer type of medication is called a GNRH antagonist. There are two brands of this medication: Ganarelix and Cetrotide. These medications do not have a flare effect. In fact, the supression of the pituitary gland is almost immediate. This is a big advantage since the IVF specialist can start the medication after the ovaries have been stimulated instead of a two week pre-treatment period as is seen with the Lupron. This makes the antagonist IVF protocol much shorter than the Lupron protocol.