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Diagnosed with LPD - Starting Progesterone this cycle

MarylandWedMarylandWed member
in TTC after 35

Hi! I'm new to this board although I have lurked... Just turned 39 and just started TTC #1. After doing some googling on spotting before your period, I asked my doctor to test my progesterone since I start spotting at 8 DPO. My 6 DPO level was 5.5 so I am starting progesterone four days after I ovulate this cycle.

I was wondering if anyone has taken progesterone and if they have had side effects, and what in general I should expect? I have never taken hormones before. I also heard the suppositories work better than pills. Is that true?

My doctor said to try this for 2-3 months and then perhaps he will refer me to an RE. I can't remember my 3DPO FSH test level but he said it was "within the acceptable range but a little higher than he would like to see."

Thanks for any advice!

Me:39 Dx LPD, Fibroid, AMA and all that goes with that. H:37 Dx low motility and low morphology. TTC since 3/12. Clomid 8/12 and 9/12: BFN. 11/12 on a break for Myomectomy sched. 11/26. Resume TTC early 2013.
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Re: Diagnosed with LPD - Starting Progesterone this cycle

  • Country Girl in the CityCountry Girl in the City
    Welcome to the board.  I am taking progesterone post IVFand took it after both IUIs.  They make me a emotional and my breasts are very sore.  They are messy so you will need a liner.  Good luck to you.
    BFP on IVF #2 6/29/2012. Beta #1 7/3 = 522; Beta #2 = 1180; Beta #3 = 6491 image BabyFruit Ticker
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  • MarylandWedMarylandWed member
    Thank you for your information regarding the side effects you have experienced - not looking forward to being more emotional than I already am :-(. I should have mentioned I was prescribed the pills - he did not offer the suppositories but have since heard they work better - however I'm not sure of that.
    Me:39 Dx LPD, Fibroid, AMA and all that goes with that. H:37 Dx low motility and low morphology. TTC since 3/12. Clomid 8/12 and 9/12: BFN. 11/12 on a break for Myomectomy sched. 11/26. Resume TTC early 2013.
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  • alibee09alibee09 member

    I just started progesterone (Crinone) for the same reason last cycle. I went from a 5 day LP to 11 day and actually had my period arrive while I was on it. (Boo!)

     

    I had no noticeable side-effects except that it made my post-O temperature very high. I also had a few days of crazy rage but that may have been PMS. :)

     

    Good luck! 

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  • MarylandWedMarylandWed member
    imagealibee09:

    I just started progesterone (Crinone) for the same reason last cycle. I went from a 5 day LP to 11 day and actually had my period arrive while I was on it. (Boo!)

    Oh no! That's not fair.

    The one he prescribed me is Prometrium.

    Me:39 Dx LPD, Fibroid, AMA and all that goes with that. H:37 Dx low motility and low morphology. TTC since 3/12. Clomid 8/12 and 9/12: BFN. 11/12 on a break for Myomectomy sched. 11/26. Resume TTC early 2013.
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  • lindaeverlylindaeverly member
    Welcome to the board!  The ladies here are very supportive & are a wealth of knowledge!  I am on Crinone suppositories right now following my first IUI.  I don't have any experience with the pills though, so I don't know if there's a big difference.  I've been cramping & severely bloated since I started them.
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  • MarylandWedMarylandWed member
    imagelindaeverly:
    Welcome to the board!  The ladies here are very supportive & are a wealth of knowledge!  I am on Crinone suppositories right now following my first IUI.  I don't have any experience with the pills though, so I don't know if there's a big difference.  I've been cramping & severely bloated since I started them.
    thank you! 
    Me:39 Dx LPD, Fibroid, AMA and all that goes with that. H:37 Dx low motility and low morphology. TTC since 3/12. Clomid 8/12 and 9/12: BFN. 11/12 on a break for Myomectomy sched. 11/26. Resume TTC early 2013.
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  • chicagobride_07chicagobride_07 member

    I've used the Crinone suppositories for 3 cycles now.  Towards the end of the cycle, I start getting really moody.  Also, I have a bit of nausea- not too bad.  It is doable, but not pleasant.

    After IUI #2, my RE put me on Endometrin.  I was only on it for two days and asked the RE to switch me back to Crinone.  For some reason, my side effects were worse on the Endometrin (which is weird because they are the same thing, essentially).

    image
    DOR and AMA
    2/12-5/12: 4 IUI cycles = all BFN;
    7/12: DE IVF # 1 (with ICSI)- 20R, 16M, 14F, 5DT of 2 blasts; 6 frosties = BFN;
    Lupus anticoagulant initially high, then found to be normal on hematology consult;
    Follow up testing in September all clear;
    Started synthroid for "high normal" TSH;
    FET # 1- late October 2012- BFP on FRER; beta # 1- 21(low), beta # 2- 48 (still low), beta # 3- 132, beta # 4- 1,293; beta # 5- 5,606; last beta- over 100,000. First u/s 11/21- heard heartbeat
    12/12- Officially an OB patient!
    Level 2 ultrasound at 20 weeks shows vasa previa and VCI
    Referral to MFM and mandatory c section for delivery
    Beautiful baby girl born at 34 weeks
    Finally home after 15 day NICU stay!
    Trying for sibling: FET # 2- May 2014; beta 5/31, BFN
    FET #3, early July 2014; beta 7/14, BFN
    DE IVF # 2- August 2014; 14R, 13M, 11F, 5dt of 2 blasts (3 AA), 5 frosties = BFN
    FET #4- December 2014, yet another BFN

    Dr. KK work up shows borderline uterine blood flow, elevated NK cells, and MTHFR mutation (homozygous for c677t)

    Added baby aspirin, prednisone, supplements, Metanx, and intralipids

    Switched to large clinic for final attempt; had endometrial receptivity testing in January; FET March 2015 = yet another BFN

    Likely OAD- NBC

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