Infertility

Looking for your experiences - Frozen Embryos

I tried searching past posts and couldnt really what I was looking for... 

So obviously everyone is different- but heres how our IVF cycle has gone. 

ER - 15 eggs, 14 matured, 13 fertilized

ET - 1 grade A embryo was transfered 3dpo, so 12 remained.

9 remaining arrested development and were discarded, so they were able to freeze 3.

I guess I am just having severe jitters now about our first beta tomorrow since only 3 made it past day 3... Thoughts experiences? Anything to help me understand?.....  :/ 

I will be posting on the PAIF as well to get there opinion...

photo ecba2e48-bd74-4395-8ca1-47ae6b5df68a_zpsfd491ced.jpg photo 5d7e0910-4031-45ed-a61f-09e4245b7ac6_zps1b85690c.jpg photo 341b9e4e-8eea-4939-9d55-a1c1cf07a00c_zpsa176d7dc.jpg

photo 84a2920e-2954-4acf-9275-ad8708055b12_zpseb05b8cb.jpg

Me and DH - 26years old; IF DX: PCOS, Hypothyroid/Hashimotos(me)
IVF #1 April 2012- 15 ER (4/13), 13 Fertilized, 1 transfered (4/16), 3 frozen
Beta #1(4/28)-127 Beta #2(4/30)-301 Beta #3(5/7)-5570!!
First ultrasound showed 1 strong little heart beat! (5/25) 7/16.. ITS A BOY!
Brayden Nicholas Born Dec 29 2012 - 7 lbs 10 oz 20 in
Baby Birthday Ticker Ticker

Re: Looking for your experiences - Frozen Embryos

  • I'm not totally exactly sure what you're asking. But I don't mean that snarkily.

    Regarding frozen embryos - most women don't have eggs to freeze, so on that account, consider yourself very lucky!

    As for your chances of being PG right now, I don't think its determinable from how long your other eggs lasted or didn't. Most docs will transfer the best embies of the bunch, so you should feel good about that.  You could POAS to find out or wait until tomorrow.

    GL!

    BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
    TTC #1 since 1/10
    DX: Unexplained/??? MFI issues

    Our lil' lost sparks:
    5w3d loss 7/30/10 - EDD March 2011
    8w loss 4/15/11 - EDD November 2011
    8w3d loss 8/2/12 - EDD March 2013
    4w c/p loss 10/29/12 - EDD July 2013

    Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
    RPL testing all normal, Karyotyping normal

    Moving on to IVF.

    IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

    Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
    IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
    FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
    Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

    After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
    We are so in love with her.

    "I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

    Everybody is welcome!!!
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  • imageBzeetyD:

    I'm not totally exactly sure what you're asking. But I don't mean that snarkily.

    Regarding frozen embryos - most women don't have eggs to freeze, so on that account, consider yourself very lucky!

    As for your chances of being PG right now, I don't think its determinable from how long your other eggs lasted or didn't. Most docs will transfer the best embies of the bunch, so you should feel good about that.  You could POAS to find out or wait until tomorrow.

    GL!

    No no - I dont take it snarky- considering the number of looks and 1 reply others may be wondering the same thing! :) I am not really asking a question - just looking for others experiences; regarding number of embryos they had to freeze, opinions on 9 arresting development out of 12. Whats normal and whats not normal i guess.. Not looking for sugary answers, just real experiences of what others have had.

    You replied with what I was looking for.  :)

     

    photo ecba2e48-bd74-4395-8ca1-47ae6b5df68a_zpsfd491ced.jpg photo 5d7e0910-4031-45ed-a61f-09e4245b7ac6_zps1b85690c.jpg photo 341b9e4e-8eea-4939-9d55-a1c1cf07a00c_zpsa176d7dc.jpg

    photo 84a2920e-2954-4acf-9275-ad8708055b12_zpseb05b8cb.jpg

    Me and DH - 26years old; IF DX: PCOS, Hypothyroid/Hashimotos(me)
    IVF #1 April 2012- 15 ER (4/13), 13 Fertilized, 1 transfered (4/16), 3 frozen
    Beta #1(4/28)-127 Beta #2(4/30)-301 Beta #3(5/7)-5570!!
    First ultrasound showed 1 strong little heart beat! (5/25) 7/16.. ITS A BOY!
    Brayden Nicholas Born Dec 29 2012 - 7 lbs 10 oz 20 in
    Baby Birthday Ticker Ticker

  • plus i think i am at the end of my rope being patient with this 2ww... Cant bring my self to POAS... false positive or false negatives scare me!

    photo ecba2e48-bd74-4395-8ca1-47ae6b5df68a_zpsfd491ced.jpg photo 5d7e0910-4031-45ed-a61f-09e4245b7ac6_zps1b85690c.jpg photo 341b9e4e-8eea-4939-9d55-a1c1cf07a00c_zpsa176d7dc.jpg

    photo 84a2920e-2954-4acf-9275-ad8708055b12_zpseb05b8cb.jpg

    Me and DH - 26years old; IF DX: PCOS, Hypothyroid/Hashimotos(me)
    IVF #1 April 2012- 15 ER (4/13), 13 Fertilized, 1 transfered (4/16), 3 frozen
    Beta #1(4/28)-127 Beta #2(4/30)-301 Beta #3(5/7)-5570!!
    First ultrasound showed 1 strong little heart beat! (5/25) 7/16.. ITS A BOY!
    Brayden Nicholas Born Dec 29 2012 - 7 lbs 10 oz 20 in
    Baby Birthday Ticker Ticker

  • I had 5 fertilize and all of them make it to transfer day (5). We put the best 2 in and let the others go for another day they were slower growers and arrested before they made it to freeze.

    So, I have the same concerns as you, knowing how quickly ours arrested after the transfer. But I know it's common for that to happen, especially since they've selected out the best at the time so I am happy with the ones we put in and struggling with the 2ww like you.

    Good luck on your beta.

    BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08
    TTC #1 since 1/10
    DX: Unexplained/??? MFI issues

    Our lil' lost sparks:
    5w3d loss 7/30/10 - EDD March 2011
    8w loss 4/15/11 - EDD November 2011
    8w3d loss 8/2/12 - EDD March 2013
    4w c/p loss 10/29/12 - EDD July 2013

    Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
    RPL testing all normal, Karyotyping normal

    Moving on to IVF.

    IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

    Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
    IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
    FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
    Beta 9dp5dt = 181, 11dp5dt = 427. 1st u/s showed a healthy heartbeat! EDD 2/16/14

    After 4 years of hoping and heartbreak, our sweet little bean was born on 2/19/14
    We are so in love with her.

    "I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

    Everybody is welcome!!!
  • I had eleven retrieved, two transferred, one made it to freeze. Good luck!

    Countless BFN(s)
    Moving to IVF

    IVF1 (ICSI): Long Lupron
    6R. 3F. 3DT. 8Cell 1Grade 2Embies. 1Frostie.
    Beta 1/22: 14 Beta 1/24: 24 Beta 1/26: 28
    Round One Result: Chemical Pregnancy

    Pressing Forward

    IVF2 (ICSI/AH/ACU): Microdose Lupron Flare
    13R. 11F. 5DT. 2TFR'ed. 1Frostie.
    Round Two Result 4/30: Harsh BFN

    FET. 2TFR'ed.
    Round Three Result 6/25: BFN
    Where do we go from here?

    Moving forward with CCRM in 2013
    ODWU revealed blocked tube(s). Lap 2/15.
    Bilateral Tubal Ligation. Stage IV Endo.
    Finally some (tough) answers.


    IVF3 (ICSI/CCS): Antagonist with EPP
    13R. We have 3 CCS Normal Embryos!


    Lupron Depot: May 2013 to August 2013
    Long awaited FET on 9/3. 2TFR'ed.
    BFP on FRER 5dp5dt: IN SHOCK!
    Beta1 9/10: 152.7! Beta2 9/12: 378! Beta3 9/14: 1224! 

    1st ultrasound 10/1: TWO beautiful heartbeats!  Overjoyed!

  • I had 23R, 20M, 17F

    13 made it to day 3
    8 made it to day 5
    2 transferred
    2 frozen

    I had 4 arrest between fert and day 3, another 5 between days 3 and 5. 

    Another 4 either didn't make it to freeze or were not high enough quality to freeze.

    I'm 38 years old with really good levels for my age. Not saying that to brag, but just to put it into perspective. Before I started IVF, I thought everyone had tons make it to freeze. I soon learned it was more likely to have none to freeze. I feel incredibly lucky to have 2. 

    Single Mother by Choice. Life didn't work out the way I planned so I did it on my own. IUI #s 1-3, unmedicated = BFN, IUI #s 4-6, 50mg Clomid, Ovidrel = BFN IVF #1: 23R, 20M, 17F. 5 day transfer 2 blasts. 2 Snowbabies BFP 6dp5dt, Beta #1 7dp5dt = 58, Beta #2 9dp5dt = 114, Beta #3 10dp5dt = 187 1st Ultrasound = 5/3, not much to see yet. 2nd Ultrasound = 5/17, TWINS!!! Hospital Bed Rest at 32 weeks due to pre-ecclampsia and severe edema. Audrey Grace, 5lbs9oz, & Lydia Louise, 6lbs, born via emergency c-section on 12/6/12 at 36w1d My IVF Journey
  • imageMelleTX:

    I had 23R, 20M, 17F

    13 made it to day 3
    8 made it to day 5
    2 transferred
    2 frozen had 3

    I had 4 arrest between fert and day 3, another 5 between days 3 and 5. 

    Another 4 either didn't make it to freeze or were not high enough quality to freeze.

    I'm 38 years old with really good levels for my age. Not saying that to brag, but just to put it into perspective. 

     

    It really does and this is exactly what i needed- just to understand how many "usually" survive to freeze- i just felt like going from 12 to 3 was a HUGE loss... seems to be the norm for some people. So thank you all for sharing so far! 

    photo ecba2e48-bd74-4395-8ca1-47ae6b5df68a_zpsfd491ced.jpg photo 5d7e0910-4031-45ed-a61f-09e4245b7ac6_zps1b85690c.jpg photo 341b9e4e-8eea-4939-9d55-a1c1cf07a00c_zpsa176d7dc.jpg

    photo 84a2920e-2954-4acf-9275-ad8708055b12_zpseb05b8cb.jpg

    Me and DH - 26years old; IF DX: PCOS, Hypothyroid/Hashimotos(me)
    IVF #1 April 2012- 15 ER (4/13), 13 Fertilized, 1 transfered (4/16), 3 frozen
    Beta #1(4/28)-127 Beta #2(4/30)-301 Beta #3(5/7)-5570!!
    First ultrasound showed 1 strong little heart beat! (5/25) 7/16.. ITS A BOY!
    Brayden Nicholas Born Dec 29 2012 - 7 lbs 10 oz 20 in
    Baby Birthday Ticker Ticker

  • **Ticker/Sig Warning!**

     

    Dr. Sher has some good articles about embryo selection for transfer and freezing

    https://haveababy.com/fertility-information/ivf-authority/embryo-blastocyst-grading-which-to-transfer-which-to-discard/

    https://haveababy.com/fertility-information/ivf-authority/cleaved-embryos/

     

    I did one round of IVF:

    36 retrieved, 34 mature, 26 fertilized normally by ICSI (we have multiple MFI issues), 11 made it to day 5/6 freeze.  I couldn't do a fresh transfer because my E2 was sky-high at retrieval and my RE wanted to treat me for OHSS and do a frozen transfer later.  We transferred a 3BB and a 4AA two months after the stim cycle and got our twins.  

    I'm sure the best embie was picked for fresh transfer, so I would be (cautiously) optimistic about the one you transferred and your frozen embie.  Good luck!!!

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  • imageinterzone:

    36 retrieved

     

    Wow and I thought I was uncomfortable from the number I had!!

     Yes It helps that the DR was so positive when he transferred them... he said it was a super star one and he was confident it would take... FX still ..:) 

    photo ecba2e48-bd74-4395-8ca1-47ae6b5df68a_zpsfd491ced.jpg photo 5d7e0910-4031-45ed-a61f-09e4245b7ac6_zps1b85690c.jpg photo 341b9e4e-8eea-4939-9d55-a1c1cf07a00c_zpsa176d7dc.jpg

    photo 84a2920e-2954-4acf-9275-ad8708055b12_zpseb05b8cb.jpg

    Me and DH - 26years old; IF DX: PCOS, Hypothyroid/Hashimotos(me)
    IVF #1 April 2012- 15 ER (4/13), 13 Fertilized, 1 transfered (4/16), 3 frozen
    Beta #1(4/28)-127 Beta #2(4/30)-301 Beta #3(5/7)-5570!!
    First ultrasound showed 1 strong little heart beat! (5/25) 7/16.. ITS A BOY!
    Brayden Nicholas Born Dec 29 2012 - 7 lbs 10 oz 20 in
    Baby Birthday Ticker Ticker

  • I had 18 R, 15 mature, 13 Fertilized. 

    None were transferred because I was too sick, and 6 made it to freeze.

    I have a friend from high school, who just had her ER. She had 40, yes 40, retrieved, 35 were mature, 29 fertilized, 22 made it to 3day, and today is 5day. I don't think there is an exact science to this, it depends on the quality of eggs and sperm. Our RE did ICSI, and I sometimes wonder had we let them fertilize naturally would we have had more to freeze? But there is nothing that I can do about it now and wondering isn't going to accomplish anything, so I have to be grateful for the 6 frosties I have waiting for me! :) 

     

    I wish you all the best and FX for a great beta! 

    imagePhotobucket

    Married 09.9.11 (Me:31 and DH:31)
    Left Tubal Ligation in 2004
    1.2.12 BFP
    1.16.12 LAP due to Ectopic @ 7w, Right Tubal Ligation
    3.19.12 IVF #1 - Stims (Lupron + Gonal F + Luveris)
    3.29 ER - 6 snowbabies (ET postponed due to OHSS)
    FET 6/6 - transferred two 4AB snowbabies
    Beta #1 6/16 = 683, Beta #2 6/18 = 1703, Beta #3 6/20 = 4073, u/s #1 @ 5wks = TWINS!!, 7w u/s two heartbeats <3<3 TWIN BOYS<br>

    ***SAIFW & PAIFW***

    Pregnancy Ticker

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