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CGH ladies

So the other day on another board, I was reading about someone doing a 5 day embryo biopsy with 24 hour turnaround. They transfer any chromosomally normal embryos on Day 6 instead of freezing on day 5. So I emailed the embryologist at my clinic, and it turns out that they can do this if I want it.

I thought this option sounded awesome, but hadn't heard of it being discussed here. Maybe it's a newer option, but I was just curious if anyone else has been offered this? The last clinic I went to would freeze on day 5 and have you do a FET at a later date.

I've been back and forth on CGH, but am learning more towards it. We are typically left with 2-3 embryos after our fresh IVF cycles. I know I could just put them all in and see what happened, but after two miscarriages (BOTH of which required intervention- one with methotrexate and one D&C), i'm really not wanting to go through that again. If I can decrease the chances of it happening, I want to.

Anyone's clinics offer them this option?


DH: Severe MFI/Azoo Me: Compound heterozygous MTHFR
IVF #1= m/c- methotrexate @6w2d
FET #1= BFN
IVF #2= m/c- D&C @8w5d
IVF #3= Beta #1 9dp5dt= 252, Beta #2 11dp5dt= 417, Beta #3 17dp5dt= 4,952
US #2 @ 7w2d= twins, baby B measuring behind
US #3 @ 8w5d= Baby A doing well, no HR in baby B
*S/PAIF always welcome* BabyFetus Ticker

Re: CGH ladies

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    No, but just wanted to say GL and I hope you get a great plan soon.  The 5 day biopsy and FET later on option really turned me off - I know ultimately we'd do it if we had to, but it's not easy to face.  I think this option of an immediate transfer is so much more attractive :)
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    My RE told me about this too but as my markers were already with the PGD team we stayed with it. He said it was a good testing method but thought that in my situation I was better off with the 5 day PGD testing and FET later.

    GL in what you decide. Maybe google it and see if any other boards out there have spoken about this.

    Multiple ectopics, 2 failed IVF's
    IVF #1: Did not get to ET, embies all failed PGD (major chromosomal defects)
    IVF #2: We have 2 chromosomally perfect embies as a result of PGD (Boy/Girl) 1 failed the thaw (Girl) Transferred 1, yet ended as a c/p
    Thought it was the end of our TTC Journey 6/20/2012
    SHOCK BFP 9/28/2012: IT'S A BOY! and everything is normal !!!!!!

    Little A born 38w 2d on 05/23/13 and is a true miracle for this IF Vet!
     

    image              

     


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    Does the 24 hour turn around test the same amount of abnormalities?  I think the quick turn around sounds pretty good.

    Good Luck LaLe!  I hope you make a great plan and get your take home baby(s) from it!!

     
    me 33/DH 36
    ttc since 10/2008; d/x: mild MFI, stageII endo
    ~~PAIF/SAIF Welcome~~
    11 IUI’s = 1 m/c (7w4d)
    IVF#1 January 2012 BFN, FET #1 April 2012 BFN
    Surprise BFP October 2012 m/c (7w), Surprise BFP April 2013 m/c (6w4d)
    IVF #2: July 2013, ET 1 embryo 7/18, beta 1 @ 14dp3dt - 757, beta 2 @ 16dp3dt - 1762
    U/S 1 @ 6w4d = 1 little frogger with HB of 118, U/S 2 @ 7w3d measuring right on track with HB of 160
    Stick Frogger Stick! Please!!!!!!!!!!!!!   It's a Girl, EDD April 7, 2014

    BabyFruit Ticker

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    Good luck!!  Are you at HFI or Houston IVF?
    I am AMA and all tests on H came back normal
    3 failed IVF with OE and 2 failed frozen DE cycles
    Last fresh hail mary DE cycle starting Feb 2013
    PAIF/SAIF always welcome
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    imageBeeBee08:

    Does the 24 hour turn around test the same amount of abnormalities?  I think the quick turn around sounds pretty good.

    Good Luck LaLe!  I hope you make a great plan and get your take home baby(s) from it!!

    Supposedly it does- all 24 chromosomes!


    DH: Severe MFI/Azoo Me: Compound heterozygous MTHFR
    IVF #1= m/c- methotrexate @6w2d
    FET #1= BFN
    IVF #2= m/c- D&C @8w5d
    IVF #3= Beta #1 9dp5dt= 252, Beta #2 11dp5dt= 417, Beta #3 17dp5dt= 4,952
    US #2 @ 7w2d= twins, baby B measuring behind
    US #3 @ 8w5d= Baby A doing well, no HR in baby B
    *S/PAIF always welcome* BabyFetus Ticker
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    imageRoxie5739:

    My RE told me about this too but as my markers were already with the PGD team we stayed with it. He said it was a good testing method but thought that in my situation I was better off with the 5 day PGD testing and FET later.

    GL in what you decide. Maybe google it and see if any other boards out there have spoken about this.

     Thanks for replying. I've been following your PGD journey- so happy to hear of your good news! good luck with the FET!


    DH: Severe MFI/Azoo Me: Compound heterozygous MTHFR
    IVF #1= m/c- methotrexate @6w2d
    FET #1= BFN
    IVF #2= m/c- D&C @8w5d
    IVF #3= Beta #1 9dp5dt= 252, Beta #2 11dp5dt= 417, Beta #3 17dp5dt= 4,952
    US #2 @ 7w2d= twins, baby B measuring behind
    US #3 @ 8w5d= Baby A doing well, no HR in baby B
    *S/PAIF always welcome* BabyFetus Ticker
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    imagedancinaggie:
    No, but just wanted to say GL and I hope you get a great plan soon.  The 5 day biopsy and FET later on option really turned me off - I know ultimately we'd do it if we had to, but it's not easy to face.  I think this option of an immediate transfer is so much more attractive :)

     Thanks for the well wishes. Happy to see that ticker on your siggy!! :)


    DH: Severe MFI/Azoo Me: Compound heterozygous MTHFR
    IVF #1= m/c- methotrexate @6w2d
    FET #1= BFN
    IVF #2= m/c- D&C @8w5d
    IVF #3= Beta #1 9dp5dt= 252, Beta #2 11dp5dt= 417, Beta #3 17dp5dt= 4,952
    US #2 @ 7w2d= twins, baby B measuring behind
    US #3 @ 8w5d= Baby A doing well, no HR in baby B
    *S/PAIF always welcome* BabyFetus Ticker
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    Hey there!! I was lurking over here and saw your post! I was the OP about the day 5 a-CGH. It does in fact test all 24 chromosomes. The reason they can turn it around so quickly is because they test it in-house. So they can turn the results around quickly without transporting (or freezing) the embryos. 

    I'm glad this can be offered to you, I have yet to find a "downside" to doing this (they can also do a 3 day if needed.) 

    GL with your decision, I can share my experience in late May/june...that's when my ER/CGH/ET will hopefully happen. My clinic has been doing this since September, before that they were doing day 5 biopsy with FET later.

    TTC#1 
    BFP 2/14/11, missed m/c 9 weeks. d&e 3/24/11
    BFP 12/10/11 d&e at 13wk+4days 2/17/12
    Dx with Balanced Robertsonian Translocation (13;14) moving on to IVF w/ PGD
    IVF #1 (May 2012) 13R, 10F, 5 blasts, ONE NORMAL frozen no transfer
    IVF #2 (July 2012) 17R, 8F, 5  blasts, ONE NORMAL 6dt on 7/12/2012- c/p
    IVF #3 (Sept. 2012) 39R, 25F, 13 blasts,  3 NORMALS! Freeze-all due to high E2.
    FET #1 10/23- 2 expanded blasts, Beta #1 11/1- 113, Beta #2 11/4-351, Beta #3 11/7- 1213
    Hailey Michelle born July 12, 2013

    TTC #2 
    FET -1/14- c/p
    IVF #4 (Feb 2014)- 49R, 28F, 13 blasts, 7 NORMALS! eSET of a normal blast on 2/24/14, 6 frosties.
    Beta #1 3/4/14- 105. Beta #2 3/7/13- 397 EDD-11/11/14. 1st u/s 3/20- 6w2d lil' bean with 120hb. 7w0d- lil bean's hb was 144. Graduated from RE 3/25/14.
      Image and video hosting by TinyPic
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    imageIronmom2be:

    Hey there!! I was lurking over here and saw your post! I was the OP about the day 5 a-CGH. It does in fact test all 24 chromosomes. The reason they can turn it around so quickly is because they test it in-house. So they can turn the results around quickly without transporting (or freezing) the embryos. 

    I'm glad this can be offered to you, I have yet to find a "downside" to doing this (they can also do a 3 day if needed.) 

    GL with your decision, I can share my experience in late May/june...that's when my ER/CGH/ET will hopefully happen. My clinic has been doing this since September, before that they were doing day 5 biopsy with FET later.

    Yes! I'm so glad that I saw your initial post. And I was shocked that my clinic actually offered it. My clinic sends out the sample. They get results in 24 hours and transfer around 1 pm on day 6. 

    I'd love to hear how your cycle goes! I'll be looking for your updates! Good luck!


    DH: Severe MFI/Azoo Me: Compound heterozygous MTHFR
    IVF #1= m/c- methotrexate @6w2d
    FET #1= BFN
    IVF #2= m/c- D&C @8w5d
    IVF #3= Beta #1 9dp5dt= 252, Beta #2 11dp5dt= 417, Beta #3 17dp5dt= 4,952
    US #2 @ 7w2d= twins, baby B measuring behind
    US #3 @ 8w5d= Baby A doing well, no HR in baby B
    *S/PAIF always welcome* BabyFetus Ticker
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    imageLaLe09:
    imageIronmom2be:

    Hey there!! I was lurking over here and saw your post! I was the OP about the day 5 a-CGH. It does in fact test all 24 chromosomes. The reason they can turn it around so quickly is because they test it in-house. So they can turn the results around quickly without transporting (or freezing) the embryos. 

    I'm glad this can be offered to you, I have yet to find a "downside" to doing this (they can also do a 3 day if needed.) 

    GL with your decision, I can share my experience in late May/june...that's when my ER/CGH/ET will hopefully happen. My clinic has been doing this since September, before that they were doing day 5 biopsy with FET later.

    Yes! I'm so glad that I saw your initial post. And I was shocked that my clinic actually offered it. My clinic sends out the sample. They get results in 24 hours and transfer around 1 pm on day 6. 

    I'd love to hear how your cycle goes! I'll be looking for your updates! Good luck!

    I'm glad I said it and you saw it, too!! That's how we all learn from each other :) I'm so glad it's offered to you if that's the route you end up going. So glad you asked! I'm so anxious to start my cycle...AF can't get here soon enough, lol! 

    TTC#1 
    BFP 2/14/11, missed m/c 9 weeks. d&e 3/24/11
    BFP 12/10/11 d&e at 13wk+4days 2/17/12
    Dx with Balanced Robertsonian Translocation (13;14) moving on to IVF w/ PGD
    IVF #1 (May 2012) 13R, 10F, 5 blasts, ONE NORMAL frozen no transfer
    IVF #2 (July 2012) 17R, 8F, 5  blasts, ONE NORMAL 6dt on 7/12/2012- c/p
    IVF #3 (Sept. 2012) 39R, 25F, 13 blasts,  3 NORMALS! Freeze-all due to high E2.
    FET #1 10/23- 2 expanded blasts, Beta #1 11/1- 113, Beta #2 11/4-351, Beta #3 11/7- 1213
    Hailey Michelle born July 12, 2013

    TTC #2 
    FET -1/14- c/p
    IVF #4 (Feb 2014)- 49R, 28F, 13 blasts, 7 NORMALS! eSET of a normal blast on 2/24/14, 6 frosties.
    Beta #1 3/4/14- 105. Beta #2 3/7/13- 397 EDD-11/11/14. 1st u/s 3/20- 6w2d lil' bean with 120hb. 7w0d- lil bean's hb was 144. Graduated from RE 3/25/14.
      Image and video hosting by TinyPic
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