Clomid Side Effects - 50 vs 100 mg

andy71781 · April 2012

I'm currently in the 2WW of my second cycle on Clomid. My doctor wants to increase my dosages from 50 mg to 100 mg. I am terrified of what kind of side effects that will cause...should I be?

notquiteblushing · April 2012

According to my RE's office "50mg is for the OBs" and they started me at 100. I didn't have any side effects.

Killer Tomato · April 2012

Even though it is double the dosage, that doesn't mean double the side effects. I've actually heard people say that they had more side effects on the 50mg dose. Others say differently. Personally, I was on 100 last cycle and am on it again this cycle, and I have not yet found the side effects to be anything you should be concerned about.

Here's hoping you won't need to worry about it!

BlueEyes313 · April 2012

I'm in the 2ww of my second clomid cycle. I started at 50 and did 100 this cycle (which I'm pretty sure didn't work and AF will be arriving soon). The only difference for me was that when I took the 100 it thinned my lining and I had to take estrogen.

andy71781 · April 2012

Thanks ladies - that makes me feel a ton better. I'm pretty sure I'm out this month and AF is on her way and feel more confident about popping the extra 50. Here's to more (but not too many) follies!

Brummy14 · April 2012

No side effects here either in the change between dosages.

GonnaBMrs.A · April 2012

I actually had a better response to the 50mg than I have with higher doses, which my RE said is not unusual. I also seem to have less side effects now that I'm on 150mg so I wouldn't worry too much about increasing your dosage.

belle4304 · April 2012

I went from 100mg to 150mg and am not sure the difference in side effects was from that... but with 100mg I only experienced hot flashes at night and with 150mg I had a headache.

tombomb84 · April 2012

I am on my 4th clomid cycle and this month was my highest dosage, yet I had the fewest s/e. I have not found a correlation between my dosage and the s/e that I have experienced.

katib77 · April 2012

notquiteblushing:
According to my RE's office "50mg is for the OBs" and they started me at 100. I didn't have any side effects.

Your RE made a very stupid statement. I ovulate on my own, so there is no need for a higher dose than 50mg for me...I always had 2-3 mature follies on 50mg of clomid. If I was put on a higher dosage, I would have had too many follicles, and probably would have been canceled.

OP - as for s/e, since I've never had 100mg, I'm not sure but I'd assume what ever side effects you've had on 50mg it just might be a little more intensified.

tombomb84 · April 2012

notquiteblushing:
According to my RE's office "50mg is for the OBs" and they started me at 100. I didn't have any side effects.

Seriously? First of all, how is including that comment helpful or relevant to the OP? Second of all, it is totally ridiculous. 50mg is for doctors that are conservative and want to make sure not to overstimulate their patients by jumping to a high dosage.

chelsmcl · April 2012

I'm happy you posted this! I start 100mg tonight for the first time and I'm a little nervous.

kflynn81 · April 2012

Can't really tell you...since I only did a cycle of 50. My RE gave it to me and was not optimistic at all that it would work. Low and behold she was right, so I went right to injects.

Weird thing though, I had s/e from Clomid (irritability, backaches, headaches) yet it didn't work but I didn't have se from the injects at all and they were able to produce at least one nice sized follie for my IUI last week. Beats me!!

Either way, good luck with you 2ww!

notquiteblushing · April 2012

tombomb84:
notquiteblushing:
According to my RE's office "50mg is for the OBs" and they started me at 100. I didn't have any side effects.

Seriously? First of all, how is including that comment helpful or relevant to the OP? Second of all, it is totally ridiculous. 50mg is for doctors that are conservative and want to make sure not to overstimulate their patients by jumping to a high dosage.

I thought it was relevant because I, too, was apprehensive about taking 100mg when I see so many others on this board starting at 50mg. But I thought knowing that starting at 100mg was my doctor's protocol would lessen her fears. She did ask for other people's experiences, no? I had no symptoms on 100mg and also did not overstimulate - I had two follicles.

katib77 · April 2012

notquiteblushing:
tombomb84:
notquiteblushing:
According to my RE's office "50mg is for the OBs" and they started me at 100. I didn't have any side effects.

Seriously? First of all, how is including that comment helpful or relevant to the OP? Second of all, it is totally ridiculous. 50mg is for doctors that are conservative and want to make sure not to overstimulate their patients by jumping to a high dosage.
I thought it was relevant because I, too, was apprehensive about taking 100mg when I see so many others on this board starting at 50mg. But I thought knowing that starting at 100mg was my doctor's protocol would lessen her fears. She did ask for other people's experiences, no? I had no symptoms on 100mg and also did not overstimulate - I had two follicles.

That's probably because your Dx is PCOS. OP did not state her Dx and does not have it in her siggy. And we don't want you to make people think 50mg of clomid is bad for everyone. Yes, it's fine to skip it for some Dx, but basically saying your doctor told you it's pointless is not helpful to all the ladies on the board. Try to remember that many Dx read these and can draw wrong conclusions from misinformation.

notquiteblushing · April 2012

katib77:
notquiteblushing:
tombomb84:
notquiteblushing:
According to my RE's office "50mg is for the OBs" and they started me at 100. I didn't have any side effects.

Seriously? First of all, how is including that comment helpful or relevant to the OP? Second of all, it is totally ridiculous. 50mg is for doctors that are conservative and want to make sure not to overstimulate their patients by jumping to a high dosage.
I thought it was relevant because I, too, was apprehensive about taking 100mg when I see so many others on this board starting at 50mg. But I thought knowing that starting at 100mg was my doctor's protocol would lessen her fears. She did ask for other people's experiences, no? I had no symptoms on 100mg and also did not overstimulate - I had two follicles.
That's probably because your Dx is PCOS. OP did not state her Dx and does not have it in her siggy. And we don't want you to make people think 50mg of clomid is bad for everyone. Yes, it's fine to skip it for some Dx, but basically saying your doctor told you it's pointless is not helpful to all the ladies on the board. Try to remember that many Dx read these and can draw wrong conclusions from misinformation.

I'm sorry. I'm new to this. I thought Clomid was primarily for folks like me who were annovulatory. Carry on!

mnj05 · April 2012

notquiteblushing:
katib77:
notquiteblushing:
tombomb84:

notquiteblushing:
According to my RE's office "50mg is for the OBs" and they started me at 100. I didn't have any side effects.

Seriously? First of all, how is including that comment helpful or relevant to the OP? Second of all, it is totally ridiculous. 50mg is for doctors that are conservative and want to make sure not to overstimulate their patients by jumping to a high dosage.

I thought it was relevant because I, too, was apprehensive about taking 100mg when I see so many others on this board starting at 50mg. But I thought knowing that starting at 100mg was my doctor's protocol would lessen her fears. She did ask for other people's experiences, no? I had no symptoms on 100mg and also did not overstimulate - I had two follicles.

That's probably because your Dx is PCOS. OP did not state her Dx and does not have it in her siggy. And we don't want you to make people think 50mg of clomid is bad for everyone. Yes, it's fine to skip it for some Dx, but basically saying your doctor told you it's pointless is not helpful to all the ladies on the board. Try to remember that many Dx read these and can draw wrong conclusions from misinformation.

I'm sorry. I'm new to this. I thought Clomid was primarily for folks like me who were annovulatory. Carry on!

Some PCOS women don't ovulate either so clomid would help.

OP - I took 50mg and 100mg and noticed more side effects on the lower dose. The only side effects I had with both doses were hot flashes and irritability. GL!

andy71781 · April 2012

Thanks again ladies! My dx is just standard issue annovulatory. I had two follies my first month and only one my second.

I'm so grateful to know that next month isn't going to suck as much as I thought it was going to!

Jerem2911 · April 2012

notquiteblushing:
According to my RE's office "50mg is for the OBs" and they started me at 100. I didn't have any side effects.

That is the dumbest thing I've ever heard. I suggest you go to a smarter RE. Oh wait...a smarter RE probably wouldn't accept someone who hasn't been TTC long.

amd1982 · April 2012

i have PCOS and did a 50mg IUI cycle + trigger back in January. I didn't get a bfp but i had a great response to the Clomid. Even though your RE is the one to blame for the incorrect information, just be careful about making blanket statements like that. 50mg of Clomid is not useless - just as 100mg isn't always necessary. Everyone's situation is different.

notquiteblushing · April 2012

Jerem2911:
notquiteblushing:
According to my RE's office "50mg is for the OBs" and they started me at 100. I didn't have any side effects.
That is the dumbest thing I've ever heard. I suggest you go to a smarter RE. Oh wait...a smarter RE probably wouldn't accept someone who hasn't been TTC long.

Are we really going to go there? People come from all over the country to go to my RE but thanks for playing.

ETA. I don't ovulate AND we have MFI so let's not play this game, k?

Shayliz · April 2012

Jerem2911:
notquiteblushing:
According to my RE's office "50mg is for the OBs" and they started me at 100. I didn't have any side effects.
That is the dumbest thing I've ever heard. I suggest you go to a smarter RE. Oh wait...a smarter RE probably wouldn't accept someone who hasn't been TTC long.

I thought the 50mg being for OBs comment was wrong, but this one is just as bad. Who cares how long NQB has been trying if she has a documented issue?

Clomid Side Effects - 50 vs 100 mg

Re: Clomid Side Effects - 50 vs 100 mg

NTNP 2009-2012 TTC since 2012:

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