Progesterone users? — The Bump
TTC After a Loss

Progesterone users?

If you use progesterone, specifically suppositories, do you have any side-effect while using it? My OB mentioned moodiness, headaches, etc. as possibilities, but I feel pretty much the same as usual. I know it is probably different for everyone, but I would like to hear your thoughts.
BFP#1 7/09 DS born 3/30/10 BFP#2 5/11 M/C 6/11 BFP#3 9/11 M/C 10/11 BFP #4 5/20/12 Pregnancy Ticker

Re: Progesterone users?

  • my boobs get huge and i get moody. it is usually like week 2 before i get side effects

    Married 11/27/09 and TTC right away
    Dx: Complete septate uterus with cervical duplication, endometrial polyps, PCOS, endometriosis, hypo thyroid, luteal phase defect
    4 uterus surgeries to correct my complete septum and to remove polyps and 2 years of seeing the RE, medicated cycles and IUIs
    Baby 1 and 2: BFP 3/3/11 with 2 babies EDD 11/1/11, M/C 4/6/11
    Baby #3: 8/11 pregnant EDD 4/27/11 and m/c:(
    Baby #4: 10/12/11 BFP! EDD 6/16/12m/c 10/26/11
    Baby #5: 3/13/12 BFP! EDD 11/25/12 ANOTHER m/c :(

    Baby #6: 2/14/13- BFP! EDD 10/24/13, CP 2/19/13
    Baby #7: 3/15/13- BFP! EDD 11/27/13, another CP
    Baby #8.  BFP 5/19/13 EDD 1/22/14. 8 was not our lucky number

    4th septum resection on 5/31/13.
    Baby #9: 6/29/13 BFP. C section scheduled for March 5th!

    My miracle baby was born March 5 at 9:33am. He was 8 lbs 12.5 oz and 21.25 inches long!

    image"">

  • I've taken it orally and via injections, but I haven't noticed any side effects. My face broke out more than normal when AF arrived this cycle, but idk if that's related or not... probably not.
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  • i get moody after about the first week on it but outside of that I didn't have many side effects - small dizzy spells the first day or two but they went away quickly and really weren't bad i'm just an over analyzer...

    BFP 1 - march 2010 - mc at 6 weeks BFP 2 - june 2010 - mc at 5 1/2 weeks BFP 3 - sept 2010 - mc at 8 weeks BFP 4 - oct 2011 - mc at 11 weeks due to tetraploidy
  • My boobs got a little sore. And maybe I was moodier but who knows if the progesterone was really to blame! :P

    [spoiler] My Blog: Grow Baby Grow

    BFP #1: 12/2009 m/c 1/2010 BFP #2: 6/2010 m/c 8/2010

    BFP #3: 10/2011 ectopic 11/2011 (right tube removed, learned left tube was probably nonfunctional due to scar tissue from infection after m/c)

    3 failed IUIs, IVF #1: 18R, 12M, 10F, 3 poor quality 5d embryos transferred= BFP #4!!!!!

    Betas: 9dp5dt: 64 ~14dp5dt: 91 (expecting miscarriage, doubling time of 236 hours) ~16dp5dt: 200~18dp5dt: 500

    First Ultrasound at 6w2d revealed two sacs, only one with a heartbeat

    LK arrived after 42 weeks on August 14, 2013! Beautiful, healthy, and happy!

    TTC#2: IVF booked for April 2015

    Surprise BFP#5 February 19, 2015 EDD: November 2, 2015

    Betas: 10dpo: 10, 14dpo: 77, 17dpo: 270

    First Ultrasound at 5w1d showed a miracle UTE baby! And right ovary ovulation to left fallopian tube.

    JD arrived at 38 weeks on October 20, 2015.

    TTC #3: Since October 2017. BFP #6 July 2, 2018 EDD: March 16, 2019 [/spoiler]


  • Progesterone supps will mimic pregnancy/AF symptoms... Sore boobs & tiredness mostly for me.
  • I get pregnancy symptoms...sore boobs, cramping, tired, nauseous/dizzy sometimes.
    29 yrs. old w/ DOR & LPD: Highest FSH 30, AMH 0.16, low antral follicle count
    IUI#1 w/ Clomid, Trigger, and Crinone: BFP 9/12/12, EDD 5/24/13, mm/c 10/13/12, Testing done = Trisomy 16
    IUI#2-8 (injectables): BFN
    IVF #1- April 2013: Only 1 follicle on max stims- Converted to IUI: BFN
    DE IVF#1: BFP!! EDD 11/20/14
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  • They made me tired and nauseous.  DH said I was moodier, but I didn't think it was too bad.  Be sure to wear a pantyliner, as they can be messy.

    TTC started Oct '10
    Me: AMA w/RSD, atypical PCOS w/IR, LPD and High Prolactin. Controlled HP post-loss.
    DH: Low-T and borderline morph
    18 cycles, 3 medicated w/RE to get to a BFP!
    EDD 9/7/12, Saw HB @7w3d,missed m/c 1/30 @8w3d, d&c 2/8
    11 AL cycles, 9 medicated/IUI cycles. All BFFN!
    Moving forward with IVF
    BFP#2 our little cycle break surprise on AL cycle 12! EDD 10/27/13
    Beta #1: 41 Beta #2: 398; perfect u/s 3/11 hb @133bpm
    u/s 3/25 one perfect hb @183 bpm, adjusted EDD 10/23/13
    MaterniT21 and carrier screens normal. It's a girl!!!
    Severe Pre-E, HFpEF, PE, AMA & IF= OAD

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    All IF/AL Welcome!
  • I have been using them for 6+ months now and I don't get any side effects. Also AF blows right through that stuff - some people have to stop taking them to get AF at 14+DPO. There is no stopping that b!tch for me!
    Me: 37 DH: 40 TTC since 9/09
    #1 BFP 1/10/11; missed m/c discovered 7w5d
    IF Dx: Endo, hetero MTHFR mutation, poor morphology
    #1 IUI: 1/18/12 = BFN
    #1 IVF/ICSI 4/2/12 = 2 x 7-cell and 1 x 5-cell transferred (3dt) = BFP!!
    H was born at 41w2d on 12/29/12 - be still my heart!
    #2 IVF/ICSI 1/19/14 = 2 x 8 cells transferred (3dt) = BFP!! EDD 10/09/14
    M&W born at 37 weeks on 9/18/14 - I am the momma of 3 boys!!!

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  • I never had any side effects from them, but I do agree about the panty liner.
    BFP#1 12/18/10 EDD 8/28/11 | 2/14/11 discovered that our baby girl had anencephaly D&C 2/17/11 at 12.5 weeks | no O or AF post loss - Dx: AO + mild PCOS = secondary infertility Provera after 70 days = AF but no O | Provera + 50mg Clomid after 110 days = AF but no O 3 rounds of 100mg Clomid + Estrogen + Progesterone = mixed O results, all BFN hysteroscopy 1/6/12 - removed fibroid tissue injection cycle #1 - 75 IU follistim + ovidrel (triggered 2/9/12) + endometrin = BFP! EDD 11/3/12 | Beta @ 13dpo = 184, 17dpo = 993, 26dpo = >5000 IT'S TWIN BOYS!! Tommy and Charlie arrived on 9/10/12 after less than 6 hours of labor at 32 weeks Image and video hosting by TinyPic Image and video hosting by TinyPic Image and video hosting by TinyPic Lilypie Premature Baby tickers
  • Last cycle was my first on the supps. I was really emotional and a little nauseated. Talk about contributing to the MF!
    BFP #1 10/6/11 | EDD 6/15/12 | MMC 11/7/11 @ 8w3d | D&C 11/14/11

    BFP #2 8/22/12 | EDD 5/5/13 | DS1 born 5/9/13

    BFP #3 4/25/15 | EDD 1/7/16 | MMC 7/2/15 @ 13w1d | D&E 7/8/15

    BFP #4 12/9/15 | EDD 8/22/16 | DS2 born 5/18/16 at 26w2d

    Just keep swimming.
  • I get headaches more than usual when i use it. I also get very sore boobs and my face breaks out. But all in all its not too bad. I just hate how the leftover comes out and I usually get pretty irratated after using it for about a week.
    8 early m/c 1 IUI ended up in m/c Currently doing IVF/ICIS/PGS TESTING ER 2-10-13 (18retrieved,13fertilized, 11embryos, and 6 made it to day 5) FET in March 2013 if any are normal from PGS testing ?
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