Trouble TTC

My AMH increased! Yippee! Anyone else had theirs improve?

I have had my AMH taken three times in the past couple of months. The first two came back as a devastating undetectable (<0.16.) Well, I had an appointment Monday where RE ordered a progesterone test, and I asked that she add AMH to the labslip just for grins. I said that I had read online that one woman (not on the bump if I recall) said hers increased by using DHEA and taking other supplements. My RE reassured me that the results just won't improve but would order it anyway.

Well, low and behold my AMH increased. Not by much, but now it's detectable at 0.24! I know that is still super low, and obviously this isn't the magic bullet that will get me KU but it sure does gives me a little more hope that maybe my doctor doesn't know everything. And sometimes you just have to press on anyways and trust yourself! I'm not sure what may have improved it, but the only change I've made is I have been taking 75mg DHEA for about 6 weeks.

My nurse was shocked, and said she had never seen it before.

So I'll ask you ladies - has anyone else seen their AMH increase? And if so, do you have an idea what improved it?

Thanks for listening because I think you're the only ones that would understand why this puts a smile on my face! Any added hope helps!

************ Signature/Ticker Warning ************
Me (32) DH (36) - Finding our way to baby #1
Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
DH: Severe MFI

12/2/11 - IUI #1- BFN 
8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

My ovaries are just for decoration

12/6/12 - Adopted five embryos that had been frozen for over ten years!
2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

6/5/13 - Adopted four new embryos that had been frozen for seven years!
 
9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
9/29/13 - m/c @ 5w1d. :(

11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

Snowflake baby is a girl! 
Our beautiful Snowflake girl arrived on July 22, 2014!   
My embryo adoption blog: Wishing on a Snowflake
 
    image      image 

Re: My AMH increased! Yippee! Anyone else had theirs improve?

  • Oh, wow! My AMH is .38 & I've never had it retested, but I'll have to do some research on this. Congrats on the improvement!!

     

    ETA: https://www.bellaonline.com/articles/art172725.asp


    ***signature & ticker warning***


    Me: 30 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
    AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!

    Him: 29 ~ perfect swimmers

    Laparotomy w/partial oophorectomy 8/2009 to remove cysts/endo.
    Stopped BCP 4/2010.
    Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
    IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN

    IVF:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
    BCP to manage endo from 10/2012 to 12/2012.
    FET w/donor embryos #1: 10/2013 Cancelled
    FET w/donor embryos #1.2: 11/2013
    ~ ET of 2 beautiful blasts on 11/27.
    Beta 1: 503(12dp5dt) Beta 2: 1035(14dpt) Beta 3: 3001(16dpt)
    Beta 4: 8503(19dpt)
    Twins with an EDD of 8/15/14! Team Purple
    G&B born 6/30/14 at 33w3d via emergency c/s.


    If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus!


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  • Thanks for the link! I had done a TON of research before bringing the idea of taking DHEA to my RE. She said that while there has been research that shows DHEA to help POF/DOR patients respond better during IVF, but she insisted that it would have no impact on the AMH itself. She said multiple times there was NOTHING I could do to improve AMH. I had read many other sites say the same. My results and your link reassure me that the AMH is still not very well understood test, doctors certainly don't know everything, and I should not let AMH alone make me feel hopeless - because it pretty much has. Ah, gotta love having some hope again!

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • Oh my gosh! I just emailed you.  That's great news!!  Now I'm thrilled to start my DHEA too.  KIT!
    TTC #1 Since May 2011 ~ Everyone Welcome
    Me (34): DOR d/t chemo/radiation, Immature Endometrial Lining, Hypothyroidism
    DH (35): MFI d/t testicular torsion and removal, Low T, Oligospermia, Anti-Sperm Antibodies, Currently on T supplements
    Sept '11-April '13 ~  Testing, failed multiple MFI treatments, saving & TONS of praying
    January 2014 ~ IVF/ICSI & PGS ~ no response to stims ~ converted to IUI ~ BFN
    February 2014 ~ On to donor embyros ~ 5 blasts!!! 
    March 2014 ~ FET #1 ~ Transferred 2 blasts ~ BFN
    July 2014 ~ Kliman's mock cycle with endometrial function test
    Sample too small for EFT, HE slide showed immature cells
    New protocol planned, saving for another biopsy for EFT
    January 2015 ~ Considering adoption options
    April 2015 ~ Privately arranged adoption of planned pregnancy
    DD#1 ~ Lillyana Violet Marie born 6/15/16, Finalized adoption 12/20/16
    July 13, 2018 ~ BFP....WTF?!?!
    7/16 Beta #1 ~ 466...7/18 Beta #2 ~ 1,077...7/23 Beta #3 ~ 5,291
    7/23 US #1 ~ 1 gestational sac seen and yolk sac
    7/30 US #2 and 1st OB appt ~ 1 perfectly round gestational sac, 1 perfect yolk sac and 1 teeny tiny heart beat seen!!!
    Lilypie Maternity tickers


  • That is awesome news!!  I just found out my AMH is low and I was devastated also!  I did tons of research and have read about DHEA.  When I called my doctor back and talked to his nurse she didn't even recommend it.  I had to ask her and then she said "Yes he does order that but usually only when the FSH is high and other labs are off"  

    I started taking it on Valentines day.  I only got 50mg pills and taking it once a day.  Do you take all 75mg once a day or do you split it up into 25mg 3 times a day?  I have read several different ways? 

    Once again I am very happy for you!!

    BabyFetus Ticker


    TTC SINCE 7/2010, BFP-10/2010 ended in miscarriage 11/2010 : (.....
    Progesterone level 4/2011= 11.29. SA normal. HSG normal.
    8/11 Clomid 50mg=BFN progesterone level 35,
    10/11 Clomid 50mg =BFN progesterone level 31,
    11/11 Clomid 50mg=BFN progesterone level 12,
    12/11 Clomid 50mg=Progesterone 31
    01/12-Break from meds-BFN
    Feb-cd3 blood work FSH(5), AMH(0.56) 02/12 Break....
    03/01/12-Clomid 50mg with IUI #1=BFN.
    04/01/12-Another round of clomid with IUI#2=BFN.
    5/8/12-Diagnostic Laparoscopy-found minimal endometriosis and small fibriod.
    June and July-much needed break
    August-Bravelle 75 with IUI#3- BFN
    September-Bravelle injects with IUI #4-BFP!! MC 10/7/12 : ( Sonohysterogram-Normal
    December- Bravelle(3 good follicles & E2 1252) with IUI#5 BFFN :*(
    July IVF #1- BFP! : )  Beta #1-245, #2- 703, #3- 1655, #4- 3553 YAY!  Praying and Praying this one sticks around!
                      1st U/S scheduled for Aug 23rd!  
    Twins!!
    We are having a BOY & a GIRL !!



  • imageNBA0703:

    That is awesome news!!  I just found out my AMH is low and I was devastated also!  I did tons of research and have read about DHEA.  When I called my doctor back and talked to his nurse she didn't even recommend it.  I had to ask her and then she said "Yes he does order that but usually only when the FSH is high and other labs are off"  

    I started taking it on Valentines day.  I only got 50mg pills and taking it once a day.  Do you take all 75mg once a day or do you split it up into 25mg 3 times a day?  I have read several different ways? 

    Once again I am very happy for you!!

    I take 25mg three times a day. I had to put a reminder on my blackberry to tell me otherwise I'd totally forget - so something I'd recommend!  I hope you get an increase as well!

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • imageccubed3125:
    Oh my gosh! I just emailed you.  That's great news!!  Now I'm thrilled to start my DHEA too.  KIT!

    Hey! I saw your email on my blackberry, but can't type on my phone well enough to give a respectable response lol. And yahoo mail is blocked at work, which is where I am. I'll reply to you when I get home tonight. I am so elated about the increase in AMH! I hope you get the same results.

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl! 
    Our beautiful Snowflake girl arrived on July 22, 2014!   
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • Yes- I've had mine tested 3 times (GYN, then 2 different RE's)- it was less than 0.16, 0.24 and most recently 0.34.  The RE said it was just "variability of the test". 

    image
    DOR and AMA
    2/12-5/12: 4 IUI cycles = all BFN;
    7/12: DE IVF # 1 (with ICSI)- 20R, 16M, 14F, 5DT of 2 blasts; 6 frosties = BFN;
    Lupus anticoagulant initially high, then found to be normal on hematology consult;
    Follow up testing in September all clear;
    Started synthroid for "high normal" TSH;
    FET # 1- late October 2012- BFP on FRER; beta # 1- 21(low), beta # 2- 48 (still low), beta # 3- 132, beta # 4- 1,293; beta # 5- 5,606; last beta- over 100,000. First u/s 11/21- heard heartbeat
    12/12- Officially an OB patient!
    Level 2 ultrasound at 20 weeks shows vasa previa and VCI
    Referral to MFM and mandatory c section for delivery
    Beautiful baby girl born at 34 weeks
    Finally home after 15 day NICU stay!
    Trying for sibling: FET # 2- May 2014; beta 5/31, BFN
    FET #3, early July 2014; beta 7/14, BFN
    DE IVF # 2- August 2014; 14R, 13M, 11F, 5dt of 2 blasts (3 AA), 5 frosties = BFN
    FET #4- December 2014, yet another BFN

    Dr. KK work up shows borderline uterine blood flow, elevated NK cells, and MTHFR mutation (homozygous for c677t)

    Added baby aspirin, prednisone, supplements, Metanx, and intralipids

    Switched to large clinic for final attempt; had endometrial receptivity testing in January; FET March 2015 = yet another BFN

    Likely OAD- NBC

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