Pregnant after IF

Q for a friend on pre-genetic screening

I did not do this during my IVF cycle so I do not have much advice to give to a friend on this.  She is in her 40's and just started her first IVF cycle last week.  She got pregnant once last year using Clomid but pregnancy did not last past 8 weeks or so.  Her RE is suggesting that she do pre-genetic screening after fertilization to see which embryos are best to implant, but it seems incredibly pricey and not covered by insurance.  If she's planning on doing an amnio anyway when she does get pregnant, do you think she needs the screening?  She was told the screening may actually damage the embryos and she's torn on what to do.  I think she was quoted a price of like $6,500 for the screening.  Like I mentioned, I wish I could give her more guidance on this, but I did not have this issue because I'm a couple of years younger than she is and she wants to get pregnant hopefully soon.  Thanks!
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Re: Q for a friend on pre-genetic screening

  • I would not do ivf again without pgd. By the way, my embryos were never frozen for pgd. I have never heard of that in any of my dealings on DE boards. They tested them, I transferred one, they froze the rest. I am PG now. 

    The first time I did PGD, none of our embryos came back normal. None. This was with a 20-year-old donor.   This past time, some were perfect and some were not. By doing PGD, we were able to transfer a perfect blast and spare ourselves the heartache of transferring one that wouldn't take. Or worse.  

    The way I look at it, we had already spent so much money on procedures, this cost was just another one. But now we never have to do it again. We have two more healthy embryos waiting for us and I'm PG with our first now. I wouldn't even consider not doing PGD  If I had to do it again. 

     

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  • I am one of those people who did it and it didn't work. After 4 losses we decided to CGH which is a bit more advanced than FISH PGD. Instead of looking at 9-12 chromosomes, CGH looks at all of them. We had 13 embryos to biopsy and only one came back normal at time of transfer (I was 30 at the time). I was so sure that everything would be fine since we transferred a chromosomally normal little girl, but the cycle ended in a chemical pregnancy. Not only did we waste the money for IVF, but we spent an additional $5K for CGH to have a chemical pregnancy.

    It is different for everyone though, although it isn't uncommon for a person to spend all that money and end up with nothing to transfer. A person who does this really needs to go into it knowing all the possible outcomes as there are no guarantees.

    Good luck to your friend!

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