If you can't use clomid?

Hinessn · January 2012

Hey ladies. I was just wondering what the typical meds are if you can't use clomid? I have my next appointment with my RE in Feb and want educate myself ahead of time.

At my last appointment they said it's highly unlikely I'll ever be put on clomid again due to the ginormous cysts and OHSS. However, this was my first month off of clomid after 4 cycles, and I don't believe I O'd. I was testing each day but never got a positive (but I know they are never 100% accurate, so I'm always a little iffy).

So if you don't use clomid, what do you ladies use?

TIA!

pulga131 · January 2012

Were you on the lowest dose of clomid? If you had OHSS and were on a high dose the logical step is to try a lower dose. You could try femara, which is similar, but usually causes less side effects. I doubt they would want to try injects b/c those produce more eggs...

Mrs.Slick · January 2012

Femara is another oral medication that many here have tried. But some RE's don't use it since its not technically a fertility med and is being used off label.

After that FSH injectable meds like Follistim may be prescribed. They're teeny tiny needles and easy to give to yourself. They do go up in cost considerably though.

Mrs.Slick · January 2012

pulga131:
Were you on the lowest dose of clomid? If you had OHSS and were on a high dose the logical step is to try a lower dose. You could try femara, which is similar, but usually causes less side effects. I doubt they would want to try injects b/c those produce more eggs...

I think the cysts she mentioned would be the main issue with Clomid.

And if properly monitored and given the low and slow method with injects, then they're completely fine even for women who have previously developed OHSS.

crystalmarcellin · January 2012

My RE put me on Femara because Clomid caused me to have 0 CM. Today is my first day taking this so I don't have any advice. But good luck with what your RE decides.

Hinessn · January 2012

I did two cycles on 50 and two cycles on 100 (none were monitored despite my requests). They assumed I wasn't responding and it turns out I was responding too well.

The RE didn't go too much into what would be next since our main objective was to have these cysts go away first. I know they've gone down since I can finally fit into my clothes again haha Not sure if they're gone completely, just smaller.

I will do some research on Femera and the injectables so I'm prepared for the next appt. Thank you!

mizzougal08 · January 2012

I was put on Femara after Clomid as well. Both Clomid and Femara did jack smack for me and eventually they moved me over to injectables (Follistim) and I responded well to that. GL!

Hinessn · January 2012

Mrs.Slick:

pulga131:
Were you on the lowest dose of clomid? If you had OHSS and were on a high dose the logical step is to try a lower dose. You could try femara, which is similar, but usually causes less side effects. I doubt they would want to try injects b/c those produce more eggs...

I think the cysts she mentioned would be the main issue with Clomid.

And if properly monitored and given the low and slow method with injects, then they're completely fine even for women who have previously developed OHSS.

This! Because of the sheer size of my cysts I am sure they have been developing for some time from the Clomid.

Mrs.Slick · January 2012

Hinessn:
I did two cycles on 50 and two cycles on 100 (none were monitored despite my requests). They assumed I wasn't responding and it turns out I was responding too well.

The RE didn't go too much into what would be next since our main objective was to have these cysts go away first. I know they've gone down since I can finally fit into my clothes again haha Not sure if they're gone completely, just smaller.

I will do some research on Femera and the injectables so I'm prepared for the next appt. Thank you!

Yikes! I hope you'll be monitored from now on, especially since they know complications have come up in part due to poor monitoring in the past. GL!

Hinessn · January 2012

Yes! My RE was appalled that I had never had an U/S before seeing him. Especially after I was complaining of pains in my abdomen in SEPTEMBER! I specifically brought up my concern of cysts but the doctor gave me the brush off and said it was cramps in between periods....mmhm.

Anyway, I'm hopeful for the future thats for sure! I very much like my RE and the whole clinic.

Mrs.Slick · January 2012

Hinessn:
Yes! My RE was appalled that I had never had an U/S before seeing him. Especially after I was complaining of pains in my abdomen in SEPTEMBER! I specifically brought up my concern of cysts but the doctor gave me the brush off and said it was cramps in between periods....mmhm.

Anyway, I'm hopeful for the future thats for sure! I very much like my RE and the whole clinic.

Isn't the peace of mind a good RE brings wonderful? It never ceases to amaze me how irresponsible some doctors can be.

Hinessn · January 2012

Yes it is! I absolutely love having someone that I actually trust. I've been pretty screwed over by the military docs so I was so relieved to get a referral. I dont even care that its 2 hours away.

The last time I was there my regular doc was unavailable, and I liked his associate just as much. I felt like my previous doctors were just throwing darts whereas here I'm getting actual answers and solutions.

waitforhimorher · January 2012

Metformin might be another alternative. As Clomid and Metformin or Clomid + Metformin are sometimes interchangeable for ladies with PCOS. What is your Dx?

Hinessn · January 2012

As of now, all I have is OHSS with cysts (last measured at 9x7cm)

At my appt earlier this month they said they are very doubtful that it is either Endo or PCOS and are confident both issues are a result of clomid. Both doctors agreed on that. But once the cysts have gone away, then we will see if there is anything else going on.

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