Risk of multiples?

HeatherandRay · November 2008

What is the risk of multiples for those of us that have IUI? What is the risk based on the # of babies..... Twins? Triplets? Quadruoplets? Five (no idea the word for five!)? Is the risk directly in proportion to the number of mature follicles you have?

I just had an IUI (with 150 mg clomid) with five big mature follicles, and am having irrational panic attacks of having a litter of 5 children. That is how John and Kate +8 started.........................

ShawMich · November 2008

No, IUI isn't what Kate had. She had IVF.

When having an IUI, you most likely will be taking Clomid or Femara. The risk of multiples with Clomid is 9% and Femara is 3% (from what my RE said).

As for a risk from just the IUI itself...someone else will have to answer that part because I don't know.

ShawMich · November 2008

Oh and by multiples, I mean twins.

eh2006 · November 2008

Oh my god, I am in the same boat as you. I had an IUI on 100 mg of Clomid and I am absolutly panicing about high order multiples. I've been googling "clomid quads" and "clomid triplets" constantly. Kate did do IUI, not IVF, it's on their website.

My RE was so dismissive about the multiples....said twins are common but he's only seen two cases of triplets the whole time he's be practicing. I was joking with my husband to pick out 5 baby names but I'm seriously worried....

NYGrlAtHeart · November 2008

Kate from Jon & Kate plus 8 did HAVE an IUI. She has been very open about this. If you had 5 mature follicles, then you can definitley get pregnant with 5. Kate said her U/S only showed 4 maybe 5 mature follicles and she had 6!!

I don't want to scare you and I am sure what happened with Kate is not very common..but that is her story. Good Luck!!

smeyer · November 2008

Chances of high order multiples are higher with IUI than IVF because there's less control. ?With IUI, the RE is making the call based upon the number of follicles seen on a u/s. ?Just b/c you have a?follicle?of a?certain?size doesn't guarantee you have a mature egg inside. ?That being said, you could have smaller?follicles or "hidden" follicles that do indeed contain a mature egg, hence J&K+8. ?With IVF, mature eggs and sperm are joined outside of the body, then the patient and doctor determine how many embryos are put back. ?Many drs will not put back more than 2. ?Having 3 or more embryos transferred requires that very specific factors be met such as maternal age, embryo quality and previous failed cycles.

Anyway... chances of HOM are slim with IUI. ?Chances of twins are about 10% (higher than "normal" conception but not super high) for IU and HOM are quite rare. ?

Think of it this way... no knowledgeable, well-respected RE wants to be presented on the national news as the person whose patient got pg with 6 babies. ?Sure it can happen, but I firmly believe that quality medical professionals do not set out with the intent of this happening. ?Chances are that your RE would not have allowed you to proceed with an IUI if he/she felt your chances of HOM were high. ?

GL! ?:)?

jensahokie · November 2008

I am doing IVF, but my close friend just did IUI#2 and is having triplets! At 6 weeks, they actually had 4 little ones, but only 3 continued to grow (now at 14 weeks).

You will be blessed with what you can handle, and I am sure you will be great!

Spockles · November 2008

ShawMich:

No, IUI isn't what Kate had. She had IVF.

Kate didn't do IVF...she had an IUI. With IVF the risk of multiples is less than IUI, because they're controlling how many embryos are put back.

leslie&brian · November 2008

As pp pointed out, Kate did have an IUI. Even though you had 5 follicles, it doesn't mean that they are all going to release or that there's a mature egg in them. My gyne said that the follicles can be empty at times. Also, she told me that there's an 8% chance of multiples (twins or triplets) on oral agents, and a 20% chance on injectibles.

Mrs.Teddy · November 2008

Ia m not sure of the exact stats, some it appears are posted above. I DO know that I work with antepartum, high risk pts & have personally cared for 3 sets of triplets conceived by IUI and currently a set conceived just usinf fertility drugs...However these in comparison to hoe many end up as singletons I am not sure.....as pp said I am sure you will be blessed with whatever you can handle

hannah&ben · November 2008

ShawMich:
No, IUI isn't what Kate had. She had IVF.

When having an IUI, you most likely will be taking Clomid or Femara. The risk of multiples with Clomid is 9% and Femara is 3% (from what my RE said).

As for a risk from just the IUI itself...someone else will have to answer that part because I don't know.

Actually you're wrong... she did not have IVF and has been pretty open about that. Think about it - if she would have had IVF she would have put *7* embryos back b/c she lost one of the babies early on and none of them are identical. Who would put 7 embryos back with IVF?

Hannah

ShawMich · November 2008

hannah&ben:
ShawMich:

No, IUI isn't what Kate had. She had IVF.

When having an IUI, you most likely will be taking Clomid or Femara. The risk of multiples with Clomid is 9% and Femara is 3% (from what my RE said).

As for a risk from just the IUI itself...someone else will have to answer that part because I don't know.

Actually you're wrong... she did not have IVF and has been pretty open about that. Think about it - if she would have had IVF she would have put *7* embryos back b/c she lost one of the babies early on and none of them are identical. Who would put 7 embryos back with IVF?

Hannah

I thought she had IVF. Sorry for the wrong information. If you read what I wrote after that statement, I said I didn't know the answer regarding an IUI. I've never had one, so I don't have any knowlege in that area.

Regardless, why would you wait until after the transfer to be concerned about multiples? Why didn't you ask your doctor beforehand??

LadyRed7 · November 2008

my RE said if we had produced 4-5 mature follies, they would have had us cancel the cycle or convert to IVF, just as pp said, there isn't the kind of control you can have with IVF as IUI. We have agreed to that at this point.

?

But i do agree with pp, you will be blessed with what you can handle.

Good luck!?

debdebtx · November 2008

If it makes you feel any better I had 4 at 16+ and 2 close behind. My E2 was just over 1100. We went through with the IUI, I felt the same way, I actually threw up I was so nervous because selective reduction was not an option for us. My Dr. said he was concerned about twins, but believed more than that was seriously unlikely.

I got a BFN on that cycle, even with all of those eggies and a great sperm count. My RE has only had one patient have quads and 20 or so patients with triplets in his many years of his practice. He has many twin pregnancies. By the way, the quad patient was an IVF'er, they put back 3 and one split.

I am moving to IVF and my RE told me that he will aim for 15-20 eggs to retrieve. We will be lucky if we get two or three that fertilize AND mature enough to transfer and even luckier we are able to freeze any. So, think of that in terms of IUI. How many of those eggies will mature and implant?

I know it is scary, I have been there and had to make the decision whether or not to go through with it. Just trust that you will be ok. I promise you will be ok. Deep breath! The good news, like me, you stim very well!

hannah&ben · November 2008

ShawMich:
hannah&ben:
ShawMich:

No, IUI isn't what Kate had. She had IVF.

When having an IUI, you most likely will be taking Clomid or Femara. The risk of multiples with Clomid is 9% and Femara is 3% (from what my RE said).

As for a risk from just the IUI itself...someone else will have to answer that part because I don't know.

Actually you're wrong... she did not have IVF and has been pretty open about that. Think about it - if she would have had IVF she would have put *7* embryos back b/c she lost one of the babies early on and none of them are identical. Who would put 7 embryos back with IVF?

Hannah

I thought she had IVF. Sorry for the wrong information. If you read what I wrote after that statement, I said I didn't know the answer regarding an IUI. I've never had one, so I don't have any knowlege in that area.

Regardless, why would you wait until after the transfer to be concerned about multiples? Why didn't you ask your doctor beforehand??

Huh? Was that directed at the original poster? Doesn't make sense though... she didn't have a transfer - she had an IUI... if it was directed at me... I don't get it... I wasn't concerned about multiples... just trying to help dispel the myth that women who do IVF get pregnant with litters of babies.

SkiGirl1080s · November 2008

Everyone is right. Kate had IVF and IUI. Her twins are from IVF and her sextuplets are from IUI.

HeatherandRay....you have a right to be worried. I'm shocked your RE still do a IUI will 5 mature follies. Most REs would cancel the cycle or convert the cycle to IVF. They'd go in and retrieve the 5 follies, fertilize in the lab and transfer 1-3 embryos back. Did your RE explain the risk of multiples? I know my RE is mandated by the state to go through those risks with you.

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