Pregnant after a Loss

Anyone else on Crinone 8%?

So I started spotting yesterday, some red, some brown. 

I called the on-call dr, and it happened to actually be MY dr. I asked her that I wanted to try vaginal progesterone because I had read that the oral wasn't as effective. I know there's no "proof" of this, but still.

So she put prescribed me Crinone, and I am doing it two times a day. Unfortunatley, it's labeled as a "fertility drug" and insurance does not cover it. So for one week's worth, it cost $200. Anything for this baby though.

Just was wondering if anyone else was on it? Side effects? Liked it? Didn't?

TIA! 

BFP #1 4/23/11, EDD 1/4/12::No heartbeat @ 9 wks::D&C 6/1/11 
Child #1  June 2012
Child #2  Feb 2014
Child #3  Feb 16
BFP 3/9/17
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Re: Anyone else on Crinone 8%?

  • I've taken it. My insurance was willing to cover it, although with the highest co-pay. 

    I didn't really have side effects although I will warn you it builds up in there and gets chunky and gross. You'll also leak, so invest in pantyliners (like, a lot of them). Whatever works, though, IMO. 

    DS 04.25.08 DS 03.14.12 missed m/c 9w1d :: 6.18.10 :: d&c | missed m/c 9w3d :: 11.2.10 :: d&c
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  • I'm on it.  My insurance covered it though... ($30 copay for 2 boxes of it)

    Anyway,

    I don't like the fact that it makes everything juicier down there which can cause panic.  There is a side effect of "build up".  This might be TMI but there is this white balled up crap that comes out of there on a regular basis.  it's kind of nasty.

    I'm only on it one time a day and it seems to be doing a great job.  

    Good luck! 

    BFP 6/20/10 1st M/C- 7/3/10~ 6 w 1 d
    BFP 9/13/10- Chemical Pregnancy discovered 9/16/10
    BFP 2/23/11 EDD 2nd M/C 3/20/10~ 7 w 6 d
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  • Is there anyway they can just give you a script for a generic progesterone suppository?  

    I can't remember what dose I was on, I think it was either 200mg or 400mg once a day and since it had to be compounded at the pharmacy it wasn't covered under insurance but it was around $60 for a month supply.  

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  • I'm on it twice a day. I happen to prefer Crinone. I like the easy applicator and that it doesn't leak out for the most part. You will need pantiliners and also need to "clean it out" every few days as it will build up in there. Also, my insurance covers it.
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  • My insurance wouldn't cover it either.  So, my doc wrote me an Rx for compound progesterone suppositories.  Same stuff basically only a waxy suppository instead of the gel.  It was only $45 for a month's worth.  It may be worth asking your doctor about.

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  • imageOlive44:
    I'm on it twice a day. I happen to prefer Crinone. I like the easy applicator and that it doesn't leak out for the most part. You will need pantiliners and also need to "clean it out" every few days as it will build up in there. Also, my insurance covers it.

    This may seem like a stupid question, but how do you go about 'cleaning it out'? With like Q-tip? Fingers?  

    BFP #1 4/23/11, EDD 1/4/12::No heartbeat @ 9 wks::D&C 6/1/11 
    Child #1  June 2012
    Child #2  Feb 2014
    Child #3  Feb 16
    BFP 3/9/17
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  • I was on it 3 DPO until 11 weeks. I only had to take it once daily though bc it was the 8% however I didn't have low progesterone it was just part of my RE's protocol.  I didn't really have side effects beyond the normal pregnancy ones. The discharge is very thick and a bit gross and sometimes would range in color from orange to brown which I guess is totally normal. I don't have any complaints about it but I wasn't sad to stop!! GL
    BFP #1 6/18/10 Saw HB 7/15/10 Missed M/C 8/17/10 @ 12 weeks 2 days- 2 D&C's( 8/20 and 8/26) BFP#2 11/21/10 Nonviable at 5wks, possible ectopic. Methotrexate 12/3/10&12/9/10 BFP#3 3/10/11 Beta@12dpo 39 Beta@14dpo 160! 21 DPO 2439 HB at 7wks 127 EDD 11/17/11
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  • imagemrs.gee:

    I've taken it. My insurance was willing to cover it, although with the highest co-pay. 

    I didn't really have side effects although I will warn you it builds up in there and gets chunky and gross. You'll also leak, so invest in pantyliners (like, a lot of them). Whatever works, though, IMO. 

    Couldn't have put it better myself. Definitely don't get the ultra-thin panty liners- I found that I would leak through them. I felt like I should have bought stock in panty liners when I was on crinone. Although I was nervous about stopping it at the end of the first trimester, I wasn't sad about constantly worrying about the state of my panties.  

    BFP#1=12/24/10 missed m/c @ 9w2d BFP#2=4/13/11 EDD 12/24/11 (coming full circle!)
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  • imagejulesjb:
    I was on it 3 DPO until 11 weeks. I only had to take it once daily though bc it was the 8% however I didn't have low progesterone it was just part of my RE's protocol.  I didn't really have side effects beyond the normal pregnancy ones. The discharge is very thick and a bit gross and sometimes would range in color from orange to brown which I guess is totally normal. I don't have any complaints about it but I wasn't sad to stop!! GL

    Wish I had known about the "orange to brown" part before freaking out this morning. I have a few more weeks of it then I'm done. 

    To the OP-check and see if your doc can give you some samples, mine gave me 2 2 weeks worth. 

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  • imageE3A7AGGIE:

    imageOlive44:
    I'm on it twice a day. I happen to prefer Crinone. I like the easy applicator and that it doesn't leak out for the most part. You will need pantiliners and also need to "clean it out" every few days as it will build up in there. Also, my insurance covers it.

    This may seem like a stupid question, but how do you go about 'cleaning it out'? With like Q-tip? Fingers?  

    As strange as it may sound you just use your finger in the shower and gently sweep some out. It can get a bit "clogged"

    BFP #1 6/18/10 Saw HB 7/15/10 Missed M/C 8/17/10 @ 12 weeks 2 days- 2 D&C's( 8/20 and 8/26) BFP#2 11/21/10 Nonviable at 5wks, possible ectopic. Methotrexate 12/3/10&12/9/10 BFP#3 3/10/11 Beta@12dpo 39 Beta@14dpo 160! 21 DPO 2439 HB at 7wks 127 EDD 11/17/11
    ITS A BOY!!!! Born 11/13/11 BFP #4: 10/29/12 edd 7/11/12
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  • I used it from BFP to 11 weeks.  I had zero side effects, just some leaking and quite a few pairs of ruined panties.  I didn't enjoy it, but like you said, I would do anything for LO.

    My insurance only paid about 20% but it still only cost me about $30 per month for generic.  I would see if your doctor would be willing to switch you once you need a refill. 

    I would suggest laying down for awhile after your non-bedtime dose to minimize the leaking, which seemed to me to be the worst right after inserting it.  I know some other PgALers said even panty liners didn't fully prevent the messes.

    I hope you have good luck with it and your spotting stops in no time! 

    BFP#1 11-26-10 MMC 1-13-11
    BFP#2 6-8-11 Eleanor Beatrice born 2-15-12
    BFP#3 9-4-13 Benjamin Lee born 4-28-14

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  • I was on it, and didn't think it was too bad. I did have to 'clean it out' in the shower though. Good luck!
    dx: PCOS
    Clomid + Met = BFP#1 12/27/10, missed MC discovered 2/9/11, d&c 2/11/11, 10w3d
    Natural cycle (just Met) = BFP#2 6/3/11, Baby A arrived 2/16/12
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  • imageemd2887:
    imagemrs.gee:

    I've taken it. My insurance was willing to cover it, although with the highest co-pay. 

    I didn't really have side effects although I will warn you it builds up in there and gets chunky and gross. You'll also leak, so invest in pantyliners (like, a lot of them). Whatever works, though, IMO. 

    Couldn't have put it better myself. Definitely don't get the ultra-thin panty liners- I found that I would leak through them. I felt like I should have bought stock in panty liners when I was on crinone. Although I was nervous about stopping it at the end of the first trimester, I wasn't sad about constantly worrying about the state of my panties.  

    Yeah, the liners with a plastic back worked better than the super-thin flexible (i.e. more comfortable) ones. And [warning, totally disgusting] I found the Crinone would kind of get regurgitated at the same time each afternoon. So for weeks at around 2:30pm I'd have a small heart attack and run to the bathroom only to find a pile of Crinone in my undies. Anyway, don't panic. It's all part of the process Smile.

    DS 04.25.08 DS 03.14.12 missed m/c 9w1d :: 6.18.10 :: d&c | missed m/c 9w3d :: 11.2.10 :: d&c
  • I was on it. The only side effects I had was pain during sex. I used my finger to clean it out every couple of days, gross but it helped.
  • I was put on it, as soon as my bloodwork confirmed I was pregnant again (I was also on it for the first pregnancy, but that pregnancy was troubled from the get-go and Crinone would not have saved it). I stayed on it, twice a day, for 13 weeks and tapered off in week 14. My insurance didn't cover it, so it was $173 for a two-week supply (ADVICE: Pharma reps often drop off coupons at oby/gyn's offices for $30 off per scrip--ask your doctor about these or google "Crinone" and contact the pharma company directly and they will mail you two coupons at a time).

    The only side effects I had, more with the first pregnancy that this one, was salmon-colored discharge and the aforementioned "chunky stuff" that required a twice-weekly, uh, clean-out. My fiancee and I were under a "no sex" edict for the first trimester, so I couldn't tell you about pain during boinking.

    Crinone isn't cheap, but I would like to think it helped me get through the first trimester, and it psychologically helped in that every day I was "doing an action" to help preserve my pregnancy--so much of this is out of our control, that any little thing I could do to keep the baby percolating made me feel that much better.

     I hope the Crinone works for you too!!!

    Me: 42, DH: 40; Surprise BFP 4/27/2011; no heartbeat at 9w3d, we miss you, Baby Manatee; D&C 6/1/2011; AF returned 6/26/2011; Ready to try for our take-home baby. 7/24/2011--BFP! Peanut born March 2012; BFP: 7/31/2013!; blighted ovum at 7 weeks 8/26/2013. Holy Cannoli! BFP 2/23/2014. EDD 11/6/2014!  

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  • I was on it at night only from 7 weeks to 12 weeks. My insurance didn't cover it, but my doctor gave me 2 weeks worth of samples. For the remaining 3 weeks, it was very pricey - about $120 or $130 - I got it by the mail at somewhat of a discount over what it would have cost from my normal pharmacy.

    I guess I am the odd one out, but I didn't really have any serious problems with discharge at all. I wore a pad just to be safe but never really needed to until close to the last week I took it. There was some discharge then, but for the most part I had little problems with that. My nausea and boob pain seemed to get worse when I started taking it, but that could have just been normal pregnancy symptoms, I don't really know.

    Good luck!

  • I've never been on Crinone before, but I have been on both prometrium and endometrin.  Both can be prescribed as vaginal suppositories.  You do get the increased discharge and can get build up, but I have heard that it is less than with Crinone.  Also, it might be coded differently so that it would be covered by insurance. 

    Best of luck to you!

    TTC #1 since 8/09
    BFP#1 - 9/2/10, EDD 5/14/11, Twins Hannah and Liam lost 11/7/10 @ 13w1d.
    BFP #2 - 2/9/11, EDD 10/13/11, LO lost 2/13/11 @ 5w4d
    BFP #3 - 5/9/11, DS born 1/13/12

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