Trouble TTC

Natural IVF

Has anyone looked into this? I'm really curious about it because my friend at work is considering doing it and keeps telling me to check it out. She has cyclic vomiting syndrome and has been told that she probably won't be able to carry a baby without triggering her illness. She is probably going to have to use a surrogate, but the drugs for regular IVF for her to have eggs retrieved would also make her sick.

 I read a little bit this morning on Natural IVF, and it sounds like it wouldn't give a normal "unexplained" infertile any higher of a chance than an IUI with injectibles?

Just wondered if anyone had any experience with this?

Age 37
TTC Since August 2010
Husband SA Feb. 2011 normal
HSG Feb. 2011, clear
Clomid April, May & June 2011, unmonitored
First visit to RE July 2011
Sonohystogram Aug 2011 normal
Sept 2011 AMH test in normal range
Sept 2011 Clomid cycle, monitored + TI = BFN
Oct 2011 Clomid + IUI = BFN
Long break -- tried on our own
IVF #1 June/July 2012 = 4 retrieved, 2 fertilized and transferred, BFP, chemical
IVF #2 Sept/Oct 2012 = cancelled due to poor response to EPP with Follistim (300), Menopur (150), and Lupron (10) Image and video hosting by TinyPic

Re: Natural IVF

  • How would one produce multiple follicles with natural IVF? I don't know if I would put that much faith into such an enormous procedure with only one, maybe two follicles. 
    image
    Little Slick
    Born 6.26.10
    Forever a Family 11.26.12
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  • imageMrs.Slick:
    How would one produce multiple follicles with natural IVF? I don't know if I would put that much faith into such an enormous procedure with only one, maybe two follicles. 

    Agreed.

    image


    MFI, Lap on 7/21/11 - Stage III/IV Endo and Polyps removed by D&C
    IVF #1 with ICSI - ER 1/20 (16R, 12M, 10F), ET 1/23 (1-10 cell and 1-8cell transferred), BFP on 1/31 Beta #1 on 2/3 = 68, Beta #2 on 2/6 = 261 EDD 10/12/12  
    Baby girl born 9/22/12

    FET #1 - 9/16/13 - BFN

    IVF #2 - ER 11/11/13 (24R, 18M, 16F), ET 11/16 (2 Grade A blasts)
    BFP on 11/23 Beta #1 = 76 EDD 8/2/14


  • Oh and cyclic vomiting syndrome sucks. I had a student with it a few years ago. I know it's usually outgrown in childhood but I can't imagine going through that long term. 
    image
    Little Slick
    Born 6.26.10
    Forever a Family 11.26.12
  • Yeah, she has been hospitalized over 80 times for it. She is stable on medication, but can't be on it if she gets pregnant, and every time she tries to stop the medication, she gets sick.

     

    Age 37
    TTC Since August 2010
    Husband SA Feb. 2011 normal
    HSG Feb. 2011, clear
    Clomid April, May & June 2011, unmonitored
    First visit to RE July 2011
    Sonohystogram Aug 2011 normal
    Sept 2011 AMH test in normal range
    Sept 2011 Clomid cycle, monitored + TI = BFN
    Oct 2011 Clomid + IUI = BFN
    Long break -- tried on our own
    IVF #1 June/July 2012 = 4 retrieved, 2 fertilized and transferred, BFP, chemical
    IVF #2 Sept/Oct 2012 = cancelled due to poor response to EPP with Follistim (300), Menopur (150), and Lupron (10) Image and video hosting by TinyPic
  • imagejekomo:

    Yeah, she has been hospitalized over 80 times for it. She is stable on medication, but can't be on it if she gets pregnant, and every time she tries to stop the medication, she gets sick.

     

    Does she know what her triggers are? My student really got to a point were it was manageable once he knew his triggers were.  

    image
    Little Slick
    Born 6.26.10
    Forever a Family 11.26.12
  • imagejekomo:

    Has anyone looked into this? I'm really curious about it because my friend at work is considering doing it and keeps telling me to check it out. She has cyclic vomiting syndrome and has been told that she probably won't be able to carry a baby without triggering her illness. She is probably going to have to use a surrogate, but the drugs for regular IVF for her to have eggs retrieved would also make her sick.

     I read a little bit this morning on Natural IVF, and it sounds like it wouldn't give a normal "unexplained" infertile any higher of a chance than an IUI with injectibles?

    Just wondered if anyone had any experience with this?

    It would ensure that fertilization takes place and you can look at the resulting embie to see who it develops. So I think the chance is a higher than an IUI where you don't know if fertilization even takes place.

    TTC #1 since 8/1/10; Me:41 and BRCA1+, DH:46
    DOR (FSH 24.3)/ terrible egg quality ; homozygous MTHFR c677t
    5 IUI's: 2/11 to 6/11 and 1/12= BFN
    OE IVF#1-4 8/11-6/12= all BFN
    DE IVF#1 11/12 bad embryos= BFN
    DE IVF #2 2/13 BFP/Beta hell: m/c 5w6d
    CFNBC 7 months, not doing well; decided on guarantee program at RBA w/frozen DE
    DE IVF #3 1/14  ET 4BB; BFP;M/C 5w1d, incomplete m/c; MVA extraction in ER 7w1d

    DE FET#1 ET 3/1714; BFP, beta 1 3/27= 197, beta 2 3/31= 1586, beta 3 4/7= 13879!!
    First u/s= Twins with HBs at 6w2d! We are Team Pink x 2!!

    K & K born 11/21/14 at 38wks 4 days

    imageimage

    SAIF/PAIF Welcome


    http://waitingforraintostop.wordpress.com

  • imageMrs.McIrish:
    imagejekomo:

    Has anyone looked into this? I'm really curious about it because my friend at work is considering doing it and keeps telling me to check it out. She has cyclic vomiting syndrome and has been told that she probably won't be able to carry a baby without triggering her illness. She is probably going to have to use a surrogate, but the drugs for regular IVF for her to have eggs retrieved would also make her sick.

     I read a little bit this morning on Natural IVF, and it sounds like it wouldn't give a normal "unexplained" infertile any higher of a chance than an IUI with injectibles?

    Just wondered if anyone had any experience with this?

    It would ensure that fertilization takes place and you can look at the resulting embie to see who it develops. So I think the chance is a higher than an IUI where you don't know if fertilization even takes place.

    Maybe. I think we've all seen fert reports with less than 100% fertilization - in fact, I don't recall a fert report with 100%. Part of the success of IVF comes from being able to produce multiple follicles and eggs and being able to choose the cream of the crop to transfer. Without meds, you have to take what you get, and there may not be any fertilization, or what does fertilize may not be of the proper quality for ET. And on top of it, these lower chances come with the same risks and costs of any other IVF/ER procedure (meds aside).

    Image and video hosting by TinyPic
    P/SAIF Welcome
    Invisible Finish Line
    3T's Traveling Ovary Blog
    7DPO Progesterone: low. CD3 BW: normal, HSG: clear
    DX: severe MFI (low all 3) and low T. Undergoing replacement therapy.
  • Your friend might also want to look into IVM-- in vitro maturation (https://www.ivf-infertility.com/ivm.php). I don't know that it is widely done. As I understand it, they take immature follicles out of the ovary, and then mature them outside the body in a dish, thus avoiding all those drugs.

    Someone I know who lost an ovary to OHSS after her first (sucessful) IVF mentioned it as something she was interested in to avoid such issues in future attempts.


    IVF #1 ET 1 d3 embryo 10/30/11 BFP
    3 Embryos frozen (1 d5, 2 d6)

    DS born 07/29/12

    FET #1 ET 1 d5 embryo 02/10/15 BFN

    FET #2 1 d6 embryo didn't survive thaw, transferred last d6. CP :(

    image
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