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Question about stopping progesterone

may2806may2806 member
in Pregnant after IF

I graduated today! I wasn't sure exactly when my last RE appt was, and when I asked the doc, he told me "Today"! Baby is actually starting to look like a baby on the u/s - I will miss getting them done weekly but NT scan is a week from Thurs so not that far away.

I was down to 1/2 cc a day of PIO, and now I'm to do 1/2 cc every other day for one week and then stop. Since I won't be with the RE anymore I guess I won't be getting my progesterone checked? How do I know I'll be ok without the PIO?

What week did you stop progesterone, and was your P4 monitored afterwards? I'm kind of nervous about this. 

Dx: High FSH, stage IV endo, homozygous C677T MTHFR and PAI-1
Early loss 10/08
Lap 1/09
IVF #1 "natural IVF" - 1 egg retrieved, missed m/c
Tried several mini-stim cycles with no response
Switched clinics - dx'd as carrier for Fragile X
IVF #2 MDL protocol Jan/Feb converted to IUI, BFN
IVF #2 take 2: Antagonist, one embie, BFN
IVF #3: Antagonist, no fertilization
One last ditch effort at OE IVF (antagonist with Clomid) cancelled
DE cycle #1 Jan/Feb 2011, BFP, ectopic
DE cycle #2 June/July 2011 - BFP
10/28/11 Baby girl lost at 17 weeks due to pre-term labor. We love and miss you.
DE cycle #3 June/July 2012 - BFP, twins, both heartbeats stopped, D&C
2 frosties but don't know what's next
FET Dec 2012: BFP! Praying this one sticks for the long haul!
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Re: Question about stopping progesterone

  • ladychicagoladychicago member

    With my first pregnancy, I dropped to a half dose at 8 weeks, stopped completely at 9 weeks, with no monitoring.   and it was fine.   The placenta is more than capable of doing the job by now.  

    This pregnancy, I stayed on until 11 weeks, but that was because I was bleeding/had a SCH.   However, both the RE and OB admitted that the PIO didn't actually do anything (if I was going to miscarry, the PIO wouldn't help/not help at that point), it was more for peace of mind than anything else.   

    Brought to you by IVF, ICSI, limited fert, and oocyte cryopreservation.
    Because we're fancy like that.

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  • Mrs. MoMrs. Mo member
    I was on 1cc of PIO daily but was told to stop cold-trukey ( and did) once I hit 10 weeks. After that point, it wasn't checked b/c that's when the placenta should have already kicked in and started to make it.


    "Most of the important things in the world have been accomplished by people who have kept on trying when there seemed to be no hope at all." -- Dale Carnegie
    "Our greatest weakness lies in giving up. The most certain way to succeed is always to try just one more time." --Thomas A. Edison
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  • kthappy76kthappy76
    I don't think it's common to measure P4 levels after the betas.  They just assume that your body will kick in when it's supposed to or in my case the placentas will.  I was on PIO until 15 wks for my FET, since I had been suppressed (didn't O), my ovaries weren't making any until later than a fresh cycle.
    TTK 9/06 / TTC 10/08 / Twins 12/11 / Life Blog
    5 REs + 3 surgical hysteroscopies for septum/lap + 3 failed IUIs
    IVF w/ICSI/AH & acu = BFP!, unexplained spontaneous m/c @ 8w2d (our little girl),
    FET w/acu = BFP!, B/G twins!, lost MP @19w, dx w/funneling cervix @20w,
    twins nearly lost to IC @21w, saved by rescue cerclage, 17P & 16w of bedrest
    Our twins born @36w4d via CS when A came foot first

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  • cbubbles2cbubbles2

    I stopped cold turkey at 11 weeks and everything was fine. My OB never checked (that I know of).

    Congrats on graduating!

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  • Imanurse03Imanurse03 member
    I stopped cold turkey at 12w6d as instructed by RE and was fine.  I don't think we even checked a P4 again after my 2nd beta back when I was around 4 weeks.  At this point, the placenta has taken over making progesterone so you should be fine!!
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  • amers83010amers83010

    First, congrats on graduating!! How exciting!!

    My RE actually didn't check my P4 at all... and I stopped cold turkey at 9w/6d. At that point your body should be producing it on its own. I was super nervous too. It's just so crazy to be off of it. But I've obviously been fine since! :)


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