Trigger with Lupron AND HCG?

Re: Trigger with Lupron AND HCG?

• bubbas mama1

  September 2011

  The Lupron in addition to the trigger shot is to help keep your ovaries suppressed & keep them from ovulating on their own. Maybe they saw something in the results of your lab work that signaled their decision to add the Lupron?!

  Good luck to you!
  

  
  
  ~*~ Our IF Journey~*~
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  Jan - July '10 - Clomid/Follistim + IUI = all BFN
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  Sept - FET #2 * 2 embies transferred = BFP
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• Ruthie04 member

  September 2011

  I am supposed to do a Lupron trigger with a HCG booster after ER. Here's my understanding of the situation: The Lupron trigger drastically reduces the incidence of OHSS. However, HCG triggers provide the needed support during your LP. So, by providing the Lupron trigger with a HCG booster, they get the best of both worlds.

  I'm definitely not a RE, but maybe your RE is thinking along those same lines??

  TTC in 2009, Dx: Unexplained IF

  Three TI cycles (BFP...miscarriage), five IUI attempts and 2.5 IVF cycles later...BFP!!
  12dp5dt: 765; 15dp5dt: 1979; 17dp5dt: 3379...TWINS!!!!!
  Our perfect baby boys were born at 36w1d!! 

  
  

  
  

  
  

  
  

  
  

  
  

  
  

  
  

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• mtlaurel

  September 2011

  Ruthie04:

  I am supposed to do a Lupron trigger with a HCG booster after ER. Here's my understanding of the situation: The Lupron trigger drastically reduces the incidence of OHSS. However, HCG triggers provide the needed support during your LP. So, by providing the Lupron trigger with a HCG booster, they get the best of both worlds.

  I'm definitely not a RE, but maybe your RE is thinking along those same lines??

  Thanks, I am pretty sure I'll be taking them both as trigger, no booster. OHSS is not a concern based on dx and previous response, that's why I'm curious about adding Lupron for trigger. My RE is also extending the time between trigger and retrieval by 2 hours. Seems hard to believe that 2 hours makes much difference...
  

  TTC #1 since June 2010
  Me: 36, DH: 42
  Dx: DOR and MFI
  
  DH: low count + very low motility; hormones all normal; Sperm DNA Frag. test = poor to fair; male karyotyping normal
  Me: FSH 13.4 + AMH 0.26 + hypothyroidism; Scratch the hypothyrodism (?); Blood clotting and immune panel all negative; endometrial biopsy normal
  
  IVF #1 (MDLF - Jul/Aug 2011): BFN (9R, 5M, 3F with ICSI, 3dt of 1 10-cell grade 2, no frosties)
  IVF #2 (EP-antagonist - Sep/Oct 2011): BFN (6R, 4M, 3F w/ ICSI, 3dt of 1 6-cell, 1 7-cell, grade 4s, no frosties)
  DE IVF #1 (shared cycle - June 2012): c/p (6R, 6F w/ICSI, 3dt 1 8-cell grade A- and 1 7-cell grade A-; no frosties)
  DE IVF #2 (shared cycle with new donor - Nov/Dec/ 2012): - BFP!!!!! 12/14/12. U/S on 12/27 shows twins!!!!!
  
  SAIFW/PAIFW
  

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• Ruthie04 member

  September 2011

  mtlaurel:

  Ruthie04:

  I am supposed to do a Lupron trigger with a HCG booster after ER. Here's my understanding of the situation: The Lupron trigger drastically reduces the incidence of OHSS. However, HCG triggers provide the needed support during your LP. So, by providing the Lupron trigger with a HCG booster, they get the best of both worlds.

  I'm definitely not a RE, but maybe your RE is thinking along those same lines??

  Thanks, I am pretty sure I'll be taking them both as trigger, no booster. OHSS is not a concern based on dx and previous response, that's why I'm curious about adding Lupron for trigger. My RE is also extending the time between trigger and retrieval by 2 hours. Seems hard to believe that 2 hours makes much difference...
  

  Oh no! I'm sorry...I should have read your post more carefully. Hmm. That's really interesting about the two hour delay. It sounds as though your RE is really taking the time to develop an individualized plan for you. I sincerely hope this is the perfect protocol for you!

  TTC in 2009, Dx: Unexplained IF

  Three TI cycles (BFP...miscarriage), five IUI attempts and 2.5 IVF cycles later...BFP!!
  12dp5dt: 765; 15dp5dt: 1979; 17dp5dt: 3379...TWINS!!!!!
  Our perfect baby boys were born at 36w1d!! 

  
  

  
  

  
  

  
  

  
  

  
  

  
  

  
  

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• Sarah226 member

  September 2011

  They triggered me with both, too.  Only 1/2 ml of HCG and 20 IUs of Lupron at 10 p.m. and then another 20 IUs of Lupron at 8 a.m. the next morning.  I never asked about the reasoning behind it but I think PPs are right about minimizing the risk of OHSS, etc.

  
  
  TTC since September 2009.
  
  IVF #2: +HPT 2/6/12! ~ Boy/Girl Twins!!
  
  
  

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