If you did PIO and got pg come in...

stepgirl21 · August 2011

My RE has me doing PIO shot in the morning right now and 1 prometrium supp at night. Transfer is on thursday and I continue the same protocol until my beta. If I am pg, they want me to do the PIO shot in the morning plus 3 prometrium supps (1 morning, 1 noon, 1 night).

Does that sound like a whole heck of a lot of progesterone? What was your protocal before and after your beta? Thanks!

ETA: My PIO shot is 1ml daily

krissybegs · August 2011

I started PIO shots (1 in the morning) right after the ET and continued until I was 10 weeks pregnant.

charmcitygirl · August 2011

krissybegs:
I started PIO shots (1 in the morning) right after the ET and continued until I was 10 weeks pregnant.

This. But my shot was at night.

krissyh21 · August 2011

Do you have a history of low progesterone at all? That is the only thing I can think of to warrant all this progesterone. When I did PIO I just did one shot a night and then I would have continued the same shot when pregnant.

I did prometrium for my successful cycle and just did the 3 supps. 3x a day until 7 weeks when my progesterone tested really good and they had me stop.

Ali212 · August 2011

krissybegs:
I started PIO shots (1 in the morning) right after the ET and continued until I was 10 weeks pregnant.

My protocol was the same except I did my PIO in the evening (personal preference, my RE didn't care what time of day I did it as long as I did it every 24 hours) and I continued until I was 12 weeks pregnant. I think I did 1 cc daily (if I recall correctly).

kthappy76 · August 2011

I did my PIO shots at night from before transfer to 15 wks., they just had me change the dose over time. I wonder why they are having you do PIO and supps... Confused

stepgirl21 · August 2011

kthappy76:
I did my PIO shots at night from before transfer to 15 wks., they just had me change the dose over time. I wonder why they are having you do PIO and supps...

I dunno by I think my nurse is crazy. I'm going to reconfirm.

CBL · August 2011

stepgirl21:
If I am pg, they want me to do the PIO shot in the morning plus 3 prometrium supps (1 morning, 1 noon, 1 night).

This was my protocol from transfer until 12 weeks. I had a history of dropping progesterone, so he wanted to be sure

AlissaCell701 · August 2011

I think thats what I was doing for my fEt. All my other fresh cycles I did pio shots in the Am and pm..

Kmarie823 · August 2011

I did PIO once a day (at night) but took 2ml. That was a clinic standard. I'm unfamiliar with the supps so maybe it would even out to about 2ml?

I did PIO until 13 weeks.

Bel4780 · August 2011

I was on PIO until about 11 weeks also, at night...my butt was a pretty color purple for quite some time, but totally worth it!

kthappy76 · August 2011

stepgirl21:

kthappy76:
I did my PIO shots at night from before transfer to 15 wks., they just had me change the dose over time. I wonder why they are having you do PIO and supps...

I dunno by I think my nurse is crazy. I'm going to reconfirm.

I was on 1.5ml for most of that time (it was an FET, I have low P4, and had just had a m/c on supps alone), maybe they can just up your PIO and you can do fewer/no supps. GL!

kme930 · August 2011

I think it's relevant whether you do an FET or fresh IVF. FETs require more progesterone supplementation than a fresh IVF because you don't have the whole ovulation process telling your body to make its own progesterone.

I don't know what my dose will be, but I know that I have to take it until 16 weeks if I'm pregnant.

kthappy76 · August 2011

kme930:

I think it's relevant whether you do an FET or fresh IVF. FETs require more progesterone supplementation than a fresh IVF because you don't have the whole ovulation process telling your body to make its own progesterone.

This. I was on much less P4 for my fresh cycle than for my FET.

rachel06 · August 2011

The only time I have ever seen a protocol like that is when there is a history of low progesterone or dropping progesterone. But maybe since you're only doing 1 ml they're doing a combo? I started PIO before my transfer but I can't remember exactly when. I did a 2cc shot daily at night. My arse was soooo sore but totally worth it. That was the only cycle where I didn't miscarry & as a result I now have DS

OH & when I came off PIO I was slowly switched over to supps. & then came off them as well.

JillRock96 · August 2011

That does sound like a lot to me. For my first IVF, I did prometrium supps three times a day. For my second and third IVFs, I just did a PIO shot at night.

iluvadam · August 2011

charmcitygirl:

krissybegs:
I started PIO shots (1 in the morning) right after the ET and continued until I was 10 weeks pregnant.

This. But my shot was at night.

This also for me.

stepgirl21 · August 2011

kthappy76:
kme930:

I think it's relevant whether you do an FET or fresh IVF. FETs require more progesterone supplementation than a fresh IVF because you don't have the whole ovulation process telling your body to make its own progesterone.

This. I was on much less P4 for my fresh cycle than for my FET.

Ah ha. I didn't know this. Perhaps this is the reason. thanks.

Dragonfly1226 · August 2011

Just the PIO shot (1 ml) until 11 or 12 weeks.

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