For those doing meds/monitoring, how many follies do you get?

sarahtoledo · June 2011

My RE wants to see 3-4 follies at my u/s because of my age (though he's been very polite about it Wink ). I wondered how many other TTCers over 35 are in the same boat.

I just got back from my CD7 u/s and there were four, possibly five follies, which is what we've been going for, but it still feels a little risky.

TIA

Love2Hope · June 2011

Mine wanted 4-6. I started out with 6 + but I only had four perfect sized ones at the time of our IUI.

ETA: RE wanted that many due to my age, 41 years old.

Mrs.McIrish · June 2011

Yeah, I always one follie. Yes, only one. But I'm DOR in a big way. Thus I'm no help...

mtlaurel · June 2011

I haven't stimmed yet, but my RE said he'd be happy with 5-6.

Mrs.McIrish · June 2011

mtlaurel:
I haven't stimmed yet, but my RE said he'd be happy with 5-6.

5-6 for IUI? That's a lot. Are you thinking she was asking about IVF?

sarahtoledo · June 2011

Mrs.McIrish:
mtlaurel:
I haven't stimmed yet, but my RE said he'd be happy with 5-6.
5-6 for IUI? That's a lot. Are you thinking she was asking about IVF?

I just read a study about this... something about 6 being a good number for over 35s... I will google it and share.

sarahtoledo · June 2011

Here's a quote, see full link at bottom. Surely there are other viewpoints, this is just what my googling turned up.

Women under 35 were at high risk for multiples when there were six or more follicles 12 mm or more in diameter. However, for women over 35, the pregnancy rate was improved when there were six or more follicles in that size range, without significantly increasing the multiple implantation rate. We need to be careful about this. There is not a sudden change in the egg quantity and quality that occurs on a woman's 35th birthday. The changes will be gradual, and the decision-making regarding a "safe" number of follicles should take that into account.

https://www.advancedfertility.com/revmultiplescoh.htm

danish16 · June 2011

I had 5 the 1st cycle with the RE, which lead to the whole "would you reduce if youd had multiples" talk that I wasn't quite ready to hear yet. Last month, I had 3-4 and they were happy with that (2 other times, including this one, I only had 1).

Mrs.McIrish · June 2011

sarahtoledo:

Here's a quote, see full link at bottom. Surely there are other viewpoints, this is just what my googling turned up.

Women under 35 were at high risk for multiples when there were six or more follicles 12 mm or more in diameter. However, for women over 35, the pregnancy rate was improved when there were six or more follicles in that size range, without significantly increasing the multiple implantation rate. We need to be careful about this. There is not a sudden change in the egg quantity and quality that occurs on a woman's 35th birthday. The changes will be gradual, and the decision-making regarding a "safe" number of follicles should take that into account.

https://www.advancedfertility.com/revmultiplescoh.htm

Wow! I'll have to read this later. Of course, I'd be lucky to get 6 eggs thru IVF so that's probably why I've never run across this. GL!

sarahtoledo · June 2011

danish16:
I had 5 the 1st cycle with the RE, which lead to the whole "would you reduce if youd had multiples" talk that I wasn't quite ready to hear yet. Last month, I had 3-4 and they were happy with that (2 other times, including this one, I only had 1).

It's a hard talk... I sometimes feel like my choices are risk multiples or don't get pg. Sad My doctor isn't pressuring me or anything, it's just a tough spot to be in.

Danish, may I ask what meds you're on? Did you have such different results with the same protocol? I was surprised that last cycle I had two good follies and this one, so many more.

danish16 · June 2011

sarahtoledo:

danish16:
I had 5 the 1st cycle with the RE, which lead to the whole "would you reduce if youd had multiples" talk that I wasn't quite ready to hear yet. Last month, I had 3-4 and they were happy with that (2 other times, including this one, I only had 1).

It's a hard talk... I sometimes feel like my choices are risk multiples or don't get pg. My doctor isn't pressuring me or anything, it's just a tough spot to be in.

Danish, may I ask what meds you're on? Did you have such different results with the same protocol? I was surprised that last cycle I had two good follies and this one, so many more.

DH was FREAKED about the 5 follies and ensuing discussion. He keeps telling me he doesn't even want me to get pregnant with twins. At this point, I think I would take anything!

The 5 follies was on 100 of Clomid (that IUI ended up being cancelled for other reasons). They repeated the Clomid for my 1st IUI, and I only had 1 that time. Next time, they tried Femara 5 mg/day for 6 days (I think most of the time they only do it for 5 days...) - that's when I had 3-4. We repeated that for this cycle, and I only had 1 (and it was ready to trigger by day 9). I seem to be on an every other cycle pattern of responding, which I suspect is related to DOR.

Love2Hope · June 2011

sarahtoledo:

danish16:
I had 5 the 1st cycle with the RE, which lead to the whole "would you reduce if youd had multiples" talk that I wasn't quite ready to hear yet. Last month, I had 3-4 and they were happy with that (2 other times, including this one, I only had 1).

It's a hard talk... I sometimes feel like my choices are risk multiples or don't get pg. My doctor isn't pressuring me or anything, it's just a tough spot to be in.

Danish, may I ask what meds you're on? Did you have such different results with the same protocol? I was surprised that last cycle I had two good follies and this one, so many more.

My doc promised me at age 41 that even with 6 follies that I only had a 2% chance for twins and triplets would not happen. Of course, I was worried too. Worried for nothing since I didn't even get pregnant during that IUI. Age does make a huge difference that is for sure.

sarahtoledo · June 2011

danish16:

DH was FREAKED about the 5 follies and ensuing discussion. He keeps telling me he doesn't even want me to get pregnant with twins. At this point, I think I would take anything!
The 5 follies was on 100 of Clomid (that IUI ended up being cancelled for other reasons). They repeated the Clomid for my 1st IUI, and I only had 1 that time. Next time, they tried Femara 5 mg/day for 6 days (I think most of the time they only do it for 5 days...) - that's when I had 3-4. We repeated that for this cycle, and I only had 1 (and it was ready to trigger by day 9). I seem to be on an every other cycle pattern of responding, which I suspect is related to DOR.

It's amazing how different bodies can be, even the same bodies, cycle to cycle!

Yeah, we would both be happy with twins, though I know you're not supposed to "try" for them. At the beginning of this process, the idea of twins terrified me, but now that I know this is likely our only shot, two would be okay.

tst1998 · June 2011

My first cycle on 100 mg Clomid I had 3 follies.

Next cycle 5 follies.

Next cycle 4 follies.

Next on 112.5 units Gonal-F I had 4 follies.

After the first one failed, we started being more comfortable going forward with more follicles, although still had to have the "if all of these fertilize and implant we are going to have to think about selective reduction" talk.

kbrodie06 · June 2011

We are llucky if I get 3- I am 41

Kristin

MelleTX · June 2011

Wow - I am soon to be 38. I produced one follicle on my own each month. On 50mg of Clomid, I started producing 2. One month did look like a third could be coming up, but usually 2. My RE did not want to do injectibles because he did not want more than 3 follicles for an IUI. And I am not sure I was comfortable with even 3.

However, I have an FSH within normal range and no known quality issues so maybe that's why. My RE says if we have to move on to IVF, he would expect 10-12 eggs at retrieval.

HeatherIcon · June 2011

Hmmm...I must have some crazy follicles. My first IVF, I had 11 follicles., 9 fertilized normally and then only 5 made it to the transfer--I stuck all 5 back in. You only live once!?!

Then #IVF--which is happening now, 9 were retrieved, seven fertilized normally and 5 made it to transfer--Yes. I put all 5 back now too.

I was some mega doses of Menopur and Follistim. 3-4 Menopur a night and 300 of Follistim this time. The first time, I was on 3 Menopur and 425 IU's of Follistim.

I am 42 now and am just going to see what happens. I take my preg test next Thursday 7/7.

I told my RE that we just need to try and make this happen. I have two more retrievals covered by insurance. We will see.

irishgirl0525 · June 2011

This last cycle I had 2, but only one of them was the right size. i don't remember each month, but it seems to me that I have had 2-3 the past 3 cyles before that.

I would be thrilled to have multiples, though I know that the news of that would probably give DH a heart attack. He would get over it though, he's kind of a "go with the flow" type of guy.

boymamaco · July 2011

HeatherIcon:

Hmmm...I must have some crazy follicles. My first IVF, I had 11 follicles., 9 fertilized normally and then only 5 made it to the transfer--I stuck all 5 back in. You only live once!?!

All the above posts, unless specifically stated, weren't related to IVF. You would expect to have more in IVF than IUI or TI.

Personally, I only had 1 with 50 mg of Clomid. Based on everything I read here - RE's wanting to see 3-4-5 follies, I feel like that is low. I brought it up to the nurse and she said that was all they wanted to see. I'm not so sure about her response, but I'm going to try Clomid at least once more.

For those doing meds/monitoring, how many follies do you get?

Re: For those doing meds/monitoring, how many follies do you get?

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