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XP: Update: cause of m/c

steff13914steff13914
in Trouble TTC

Hi ladies! This is a post and run. Just wanted to let those of you who asked know what the results are of the chromosome analysis we had done after my m/c.  It came back as Trisomy 16, which means that my egg had one too many copies. There is no reason it should happen again, and our RE feels confident that we have the same chances of a normal pregnancy as regular couples. I?m glad to know what caused it, but I pray it doesn?t happen again. The chances are very slim. So we are staying confident and looking forward to our cycle in June when, we?ll hopefully do our 2nd IUI.

TTC since 04/2010
Ovarian cancer survivor
DH= low motility
2/9/11 lap & hysteroscopy- uterine polyp & scar tissue removed
3/25/11 IUI#1= BFP m/c; D&C at 7w3d (Trisomy 16)
IUIs #2, #3, #4 and #5= BFNs
Onto IVF #1= BFN
FET 4/6/12= 2 extended blasts transferred, with one hatching
Beta 1= 607; Beta 2= 1,564; Beta 3= 24,439; Beta 4= over 64,000
First u/s on 5/10= TWINS! Heartbeats 158 and 160!
It's a boy and a girl!
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Huge congrats to my beautiful BFPB lmj8284, due June 2012!
"When you get to the end of your rope, tie a knot and hang on." -FDR
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Re: XP: Update: cause of m/c

  • besu-chanbesu-chan
    So sorry again for your loss. I hope these answers help ease your mind and that this next IUI will be your take home baby!!
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  • Trish11278Trish11278
    I am so sorry for your loss! 
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  • STL34STL34 member
    So sorry for your loss.  ((HUGS))  I know it doesn't help with the pain of the loss, but hopefully knowing the cause wasn't something that has an increased chance of happening again puts your mind at ease as you approach IUI #2. 

    imageimage


    ~SAIF/PAIF/Everyone Welcome~ 

    Me= 37 and DH = 41 

    Dx: DOR, Endo, APA+ (really high beta 2 glycoprotein antibody and high everything else tested), heterozygous MTHFR mutation, positive for lupus anticoagulant, high FSH, low AMH and both tubes blocked (per HSG on 3/8/11)

    IVF #1 - long lupron (with HGH, intralipids, lovenox and BA); 4 retrieved, 3 fertilized; ET 2 blasts and 1 frozen = BFN

    IVF #2 - a version of antagonist with EPP (with HGH, intralipids, lovenox and BA); 6 retrieved, 4 mature, 3 fertilized, 2 blasts and 1 frozen blast transferred on day 5 = BFN.

    IVF #3 April was postponed to May, May was canceled. June/July was canceled. Had a cyst aspiration and then began IVF #3 in August. ER on 8/22; ET on 8/24 with AH. +HPT on 9/5. Beta #1 (11dpo) = 3; Beta #2 (15dpo) = 29; Beta #3 (17dpo) = 60; Beta #4 (19 dpo) = 118. Heartbeat at 6 weeks 6 days =132.  Lil is here!

    TTC#2:  Trigger + TI = BFN; Clomid + Trigger + IUI = BFN.

    IVF #4:  BCP + MDLF + Lovenox = 7R, 1F = Transferred 1 6-cell embryo on day 3 = BFN

    IVF #5:  MDLF + Lovenox = 4R, 1F = Transferred 1 10-cell compacting embryo on day 3 = BFN

    IVF #6:  (New RE):  Long Antagonist November 2014 (transferred two 8 cell grade 1 embryos and froze one blast) = BFN

    FET#1:  BFN

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  • alhalalhal member
    I'm glad to hear that chances are very slim that the same thing will happen again.  I know I've said it like 10 times, but I'm very much looking forward to you joining me on the tri boards SOON!

    image
    9/2010: First visit to RE = CD3 b/w (normal); CD7 ultrasound (normal); DH's SA (normal but morph wasn't analyzed, so doc ordered a 2nd SA); Prog. supplements starting 3dpo for all future cycles
    10/2010: SHG to check tubes (normal!) & DH's 2nd SA (normal)
    2/2011: Start first Clomid + Ovidrel + IUI cycle = BFN
    3/2011: IUI # 2 (Clomid + 50iu Follistim + Estradiol + IUI) = BFP!!!
    Beta #1 (14 dpo)= 161
    Beta #2 (17 dpo)= 518
    Beta #3 (24 dpo)= 7,728
    BFP Chart
    Ryder arrived a month early on November 28, 2011!
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    BFP Chart 2.0 - First cycle trying without RE intervention!
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  • punkymamapunkymama
    I hope the answers bring you some comfort and I am excited/happy for your IUI in June.  Big squishy hugs to you, doll!
    <3 Tons of love and hugs to Ricola & Baby Alex <3 <br> MySweetBaboo, IRL friend, always rooting for Baboo #2, love ya girl!<3 <br> 7.7.11 BFP | 3.19.12 EDD | 3.14.12 Baby Girl's BDay
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  • 99luftballoons99luftballoons
    I am happy to hear that you have a cause and that it's unlikely to happen again. I know it doesn't make it better, but I know it must make you even more hopeful about the future.  Sending lots of vibes for June (looks like we are cycling in June too!)
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  • CluckyEVCluckyEV member
    Sorry for your loss.  T&P that this does not happen again & IUI #2 is the one!  I know it does not eliveate your pain, but it must be nice to have an explination. ((hugs))

    "When the world says, 'Give up,' Hope whispers, 'Try one more time.'" -Anonymous

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  • cutebride73cutebride73 member
    My 2nd loss was due to Trisomy 16 as well.  I am really sorry.  I am sure you will have success the next time, it is just hard to feel confident, I know.  Best of luck.  (((hugs)))
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  • missycrissy3missycrissy3 member
    Steff Im so happy to know it was an issue with the egg and not you. I have everything crossed that your next IUI will be successful and you will get your take home baby!! We miss you and cant wait for you to be back to bumping.
    <a href="http://s870.photobucket.com/albums/ab264/missycrissy3/?action=view
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  • GregermisGregermis member
    Still so sorry for your loss, but I hope IUI is your sticky one!
    TTC #1 Since 4/2010, Cycle 30
    Positive for HLA-B27, I'm a mutant :p
    Testing - Me ok, gluten issue? DH - borderline count, low motility
    4/28/11 IUI#1 = BFP!(5/25), EDD 2/2/12 - m/c 5w3d
    7/3, 7/31, 9/25 - IUI#2-4=BFN
    IVF#1 - 1 blast = BFP!! (12/30), EDD 9/9/12, confirmed c/p 4w2d
    FET#1 3/2/12 - 2 blasts =BFP!! EDD 11/18/12, us#1 = twins! Confirmed m/c 5w6d
    4/20-surprise BFP and another c/p 4w2d
    FET#2 7/16/12 - 2 blasts = BFN
    FET#3 8/20/12 - 1 blast - BFP!! Beta #1-2=177, 354
    1st u/s 5w6d, one beautiful little HB :), 2nd u/s 146bpm
    baby girl born 5/10/13

    TTC#2 since 12/17/2014, Cycle 8
    Repeat Testing...FSH=12, AMH=3.8, AFC=28. 
    IUI#5 5/10/15- c/p?
    IVF#2 8/19/15 - cancelled due to cysts
    IVF#2 take two 10/2015 - 5 blasts frozen
    FET#4 12/11/2015 - BFN - 4 blasts remaining
    FET#5 2/18/16 - BFP!!!  Beta1-3, 126, 250, 745!!

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    Tons of love and ((hugs)) to my IF sister NMscubagirl


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  • fishstix2020fishstix2020

    terribly sorry ~ but hoping the answers make it easier to cope and heal...

    best of luck in June!

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  • tshotttshott member
    I am so sorry for your loss.  I'm glad to hear that you got some answers and know that it has a low chance of happening again.  Best of luck to you in June!
    image
    Mrs. Little Drew 10/25/08
    Blog
    TTC since 1/2010 - Dx with Stage IV Endo
    11/10 - 100mg Clomid + trigger + IUI + Estradiol + Progesterone = BFN
    12/10 - Unmedicated cycle due to RE not doing treatments in December = BFN
    1/11 - 100mg Clomid + trigger + IUI + Estradiol + Progesterone = BFN
    2/11 - Same sh!t, different month = IUI cancelled due to no response = BFN
    IVF #1 - Start stims (Follistim) 5/10, add in Ganirelix 5/14
    ER 5/21 - 13 retrieved, 7 mature, 5 fertilized; ET 5/26 - transferred one perfect 1AA blast. 3 snowbabies.
    Beta 6/3 - 15.8; Beta 6/7 - 21.8; Beta 6/10 - 7 :(
    FET - Transferred 1 AA blast 7/11. Beta 7/20 - 311! Beta 7/22 - 784!! First u/s 8/10
    *~PAIFW/SAIFW~*
    BabyFruit Ticker
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  • Kathy4678Kathy4678 member

    I am glad that you at least have some answers.

    <3 you friend!! xoxo

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  • Cheetara2Cheetara2 member

    So sorry again for your loss :( I'm glad you were able to get some answers. T&Ps that your next cycle will be successful.

    IUI#3 brought us our dragon baby Z

    Lilypie Angel and Memorial tickers

    TTCAL January 2015 Siggy Challenge: Animal Snow Interactions 


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  • ChicagoWeded2007ChicagoWeded2007 member

    Hey, we also had Trisomy 16. 

    Just to clarify, the baby had one extra copy of chromosome number 16, (so three instead of two).  It is incompatible with life and it is a random occurence.  It's not genetic and there's nothing we could have done to prevent it.

    Good luck next time!


    Be kind, for everyone you meet is fighting a hard battle. -Philo
    image


    Baby N conceived after 1 miscarriage and more than 2 years of TTC. Diagnosis was low sperm count. We found success after 3 months of anastrozole to increase DH's testosterone and one IUI.
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    I'm stupid. You're smart. I was wrong. You were right. You're the best. I'm the worst. You're very good-looking. I'm not attractive. - Happy Gilmore
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  • LindzKLindzK member
    I'm so sorry to hear about your loss. That sounds like a highly unlikely chance for it to happen again, which is great!
    Me=30, DH=31
    Together since 2000, Married 10/17/2009
    TTC since 2/2010,Dx with PCOS 12/2010, taking 1500mg Metformin
    2/11-6/11 Medicated cycles w/RE
    7/11-9/11 Break from RE
    Suprise BFP 10/7/11! DD born 6/14/2012!!!
    Baby Birthday Ticker Ticker

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  • hismrs119hismrs119
    I'm so sorry about your loss. Wishing you the best for IUI #2! :)
    TTC #2 since 2/2010
    1/2011 My Dx: 1 Polycystic Ovary
    Husband Dx: Hypothyroidism= Low Testosterone & Low Sperm Count (7.4 m/mL)
    4/2011 Husband began thyroid meds
    5/2011 Begin OPK, Provera 10mg & Clomid 50mg= +OPK CD-17= BFN
    6/2011 SA-Sperm Count lower (2.2 m/mL), Testosterone slightly higher, Thyroid improving.
    Husband prescribed Clomid. Taking a break from my Clomid until we see SA results 9/2011. I will continue Provera as needed.
    7/2011 Unmedicated Cycle= +OPK CD-16=?
    imageimage image
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