Secondary IF

Anyone else dealing with MFI?

Sorry, I think I asked this question a while ago when I first joined the board, but now I can't remember if anyone was or not.

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Re: Anyone else dealing with MFI?

  • Yup, we are.  Counts are okay, motility low on one SA, okay on 2 others, and very low morphology.  We just did our 1st IUI, but ended up with a disappointing 0% morphology on the day of the IUI.  Sigh.  How are things going for you all?  You're in the 2ww right?
    TTC #1 May 2007
    M/C January 2008
    DS February 16th, 2009

    TTC #2 July 2010
    Diagnosed MFI
    IUI#1 w/ bravelle 5/12/11 -- 0% morph on day of IUI, but somehow BFP:
    Beta #1 38 at 12dpiui, Beta #2 85 at 14dpiui Beta #3 1100 at 19dpiui
    DD born December 28, 2011 at 34w6d

    Baby #3 due June 14, 2015

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  • Ugh, so did they do the IUI anyway even though there was 0% morph?  Our counts were okay, if I remember right I think it was 12 - 13 mil/mL, pretty good motility and 4% morph. He had varicocele surgery at the end of March and is on clomid as well.  We are hoping to see some improvement in July.  Until then, the RE said to do clomid, trigger and TI.  I am just worried that we are wasting our time and money because sometimes clomid for men actually makes their counts go down.  I am hoping that hasn't happened, but we don't have any way to know until they do the repeat SA in July.  This is our first clomid cycle so I guess we will see what happens.  I am in the 2WW.  That is why I am posting so many topics, I just can't seem to help myself when in the 2WW! :)  Are you in the 2WW as well then if you just did the IUI?  I have heard that some doctors don't think that morph plays a big role, so maybe it will work anyway!  I hope so!
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  • My Dh has a high number of malformed guys.  It's on the list of reasons why they're recommending we do ivf with ICSI and PGD. Our doctor thinks it's also a part of why we've had so many losses.
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  • Sorry, smacb.  I hope that the ivf with icsi and pgd helps get you your bfp.  Have either of you tried any vitamins for DH like fertil life or any other ones?  I have heard a lot about them on a MFI board that I go to sometimes, but we haven't tried anything.
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  • imagejennykg1477:
    Sorry, smacb.  I hope that the ivf with icsi and pgd helps get you your bfp.  Have either of you tried any vitamins for DH like fertil life or any other ones?  I have heard a lot about them on a MFI board that I go to sometimes, but we haven't tried anything.

     

    We have so many problems, at this point we're sticking with what the doctor said.  We tried vitamins,etc. before we went  to the RE.  I think part of the issue is that Dh smokes.  Another issue is that he was in the Marine Corps for thirteen years and exposed to who knows what.

    Our Re recommended doing ivf a year ago. We didn't have the money at the time, so we did three iui cycles.   

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  • Yes, we have MFI!!  DH's count is very low!!  Our RE has also suggested IVF with ICSI, but DH isn't completely on board yet.  I think he is starting to realize that it would be our best bet.
    imageLilypie Premature Baby tickers Lilypie First Birthday tickers image Doriimage
  • Ah so that is what you meant in the other post about the numbers being bad, Melis.  What is bad, what are his numbers?  Have they checked for a varicocele or anything?  I would assume you have probably been through all of that already.  Did you have trouble with #1 also?  Ugh, all of this talk of doctors recommending ivf is scaring me!  My DH refuses to do that or IUI for religious reasons (he likes to follow the rules).  I really hope that we can get pregnant without it.  He did have varicocele surgery though, so we will have to see if that improved anything.

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  • smacb, I hope the new course of treatment works for you!
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  • ::raises hand::  DH has severe MFI.  Last SA, he had about 700,000 sperm with low motility.  Our last IVF w/ ICSI, we only had one embie even fertilize due to his issues.  It is frustrating because they are unable to determine which are the "good" sperm to inject with ICSI.  Even the ones that appear normal to the lab apparently have issues. 
    image
    Baby Birthday Ticker Ticker
    TTC #2, Operative hysteroscopy March 2011; IVF #1 long lupron protocol April 2011-cancelled due to poor response; IVF #2 flare protocol May 2011=hospitalization due to abdominal hemorrhage during ER and no fert due to MFI issues. Moving onto international adoption from Moldova January 2013!
  • Sorry that you are dealing with this Stacy!  It is so frustrating.  I was really upset when I found out that our problem really was with DH because I felt like I had no control of the situation.  If it was me who had the issue I would feel a little more in control (maybe).  Have they given you any reason why his counts are so low?
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  • imagejennykg1477:
    Sorry that you are dealing with this Stacy!  It is so frustrating.  I was really upset when I found out that our problem really was with DH because I felt like I had no control of the situation.  If it was me who had the issue I would feel a little more in control (maybe).  Have they given you any reason why his counts are so low?

    I find myself wishing it was me who had the issue too.  I think they have more answers when it comes to infertility on our side then infertility in men. Plus, I think I would be more proactive than DH when it comes to seeking out answers.  Most REs just think that IVF w/ ICSI will overcome any MFI problem, but that is not always the case.  The cause of DH's MFI is unknown.  His bloodwork is normal, there are no blockages, and they have run every other test known and they all come back ok.  It is frustrating. 

    image
    Baby Birthday Ticker Ticker
    TTC #2, Operative hysteroscopy March 2011; IVF #1 long lupron protocol April 2011-cancelled due to poor response; IVF #2 flare protocol May 2011=hospitalization due to abdominal hemorrhage during ER and no fert due to MFI issues. Moving onto international adoption from Moldova January 2013!
  • imagejennykg1477:

    Ah so that is what you meant in the other post about the numbers being bad, Melis.  What is bad, what are his numbers?  Have they checked for a varicocele or anything?  I would assume you have probably been through all of that already.  Did you have trouble with #1 also?  Ugh, all of this talk of doctors recommending ivf is scaring me!  My DH refuses to do that or IUI for religious reasons (he likes to follow the rules).  I really hope that we can get pregnant without it.  He did have varicocele surgery though, so we will have to see if that improved anything.

    Our last IUI they were only able to inseminate a total of 800,000 in 2 days.  We have always had this problem and we got pregnant with IUI the first time, but his count was much higher, it was 7 million.  He does have a varicocele, but the urologist said that even if he as surgery it probably won't change his count.  That is our last hope and we maybe going to have it fixed soon.  How was your DH's recovery?
    imageLilypie Premature Baby tickers Lilypie First Birthday tickers image Doriimage
  • imagejennykg1477:
    Ugh, so did they do the IUI anyway even though there was 0% morph?  Our counts were okay, if I remember right I think it was 12 - 13 mil/mL, pretty good motility and 4% morph. He had varicocele surgery at the end of March and is on clomid as well.  We are hoping to see some improvement in July.  Until then, the RE said to do clomid, trigger and TI.  I am just worried that we are wasting our time and money because sometimes clomid for men actually makes their counts go down.  I am hoping that hasn't happened, but we don't have any way to know until they do the repeat SA in July.  This is our first clomid cycle so I guess we will see what happens.  I am in the 2WW.  That is why I am posting so many topics, I just can't seem to help myself when in the 2WW! :)  Are you in the 2WW as well then if you just did the IUI?  I have heard that some doctors don't think that morph plays a big role, so maybe it will work anyway!  I hope so!

     

    They did go ahead and do the IUI.  What the RE said was that we'll go ahead and do it anyway, since the sperm were already washed, but that I needed to "seriously consider where we go from here," if I don't get pregnant.  I'm not putting much hope in this cycle.  Even with so little hope, the 2ww is so hard!  So much harder than when not going through treatments.  I hope the varicocele surgery worked.  Will you guys automatically do an SA in July, if you're not pregnant of course!  :)  And if I remember right your follies were good right?  How exciting!  

    TTC #1 May 2007
    M/C January 2008
    DS February 16th, 2009

    TTC #2 July 2010
    Diagnosed MFI
    IUI#1 w/ bravelle 5/12/11 -- 0% morph on day of IUI, but somehow BFP:
    Beta #1 38 at 12dpiui, Beta #2 85 at 14dpiui Beta #3 1100 at 19dpiui
    DD born December 28, 2011 at 34w6d

    Baby #3 due June 14, 2015

    image
  • Stacy - I know!  I would definitely be more proactive than DH.  He goes to the appointments and I can't always go with him.  He never asks follow-up questions or really gets the details.

    Melis - I wonder why your urologist said the surgery wouldn't help?  Our urologist said that it improes things for 66% of men.  I also post on fertility friend in a varicocele group and so many of those ladies have gotten their bfp after the surgery.  Almost everyone's count seems to have gone up 3 months after the operation.  I would definitely consider it!  My DH's recovery was not too bad.  He was in pain for a few days, but he was back at work 3 days after the procedure.  Even the day he got the operation he was able to walk around, although I don't think it was too comfortable for him.

    Cville - What does the doctor mean by "seriously consider where you go from here"?  Does he mean that ivf might be the only way?  I hope that this IUI works anyway.  Yes, we will do another SA in July if I haven't gotten prego by then.  My follies were good, but I really don't think that I am the problem.  I just hope that his little guys can accomplish their mission! Big Smile 

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  • I'm sure I am late on posting since I haven't been on as much due to our forced break from treatments.  DH & I are MFI as well.  It appears that morph is our biggest issue.  Not sure about egg quality issues as we have not done IVF yet so who knows, it could be a factor but they don't seem to think it is since I have already had a child once before and they still consider me on the young side.  I turn 32 this year so I def. don't feel like I'm on the young side any more!  We will not be doing anything IF treatment wise until my DH passes his engineering test and gets his big raise.  I cannot wait until 2012!!!!
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