XP: MFI Ladies

softbalangel · May 2011

I have a couple questions for you ladies who are dealing with MFI issues. H and I have another IVF consult next week with our RE to go over different options.

Our RE recommended Embryo Banking and then having all the embryos tested, then doing a FET. The cost of this is over double what a single IVF cycle would be and pretty much financially out of reach for us as we are OOP for everything but meds.

My question is, was anyone else in this situation and what did you choose to do? Pros and Cons to doing/not doing the testing?

We will obviously consult with our RE but I also would appreciate opinions from those who have been in this situation as well. Currently we are leaning towards doing one IVF cycle using my H?s sperm and if that doesn?t work, moving on to donor sperm.

ChicagoWeded2007 · May 2011

I'm sorry, I have not been in this situation.

Some more info might help though. How low are your husband's numbers. Why are they recommending this course of action? Have you had failed IVFs before?

softbalangel · May 2011

ChicagoWeded2007:

I'm sorry, I have not been in this situation.

Some more info might help though. How low are your husband's numbers. Why are they recommending this course of action? Have you had failed IVFs before?

My husband has low count and low motility. The last consultation we had with the RE's office was over the phone to get the results of a couple tests. We are meeting with them next week to discuss it some more.

I would assume the embryo banking is recommended due to the sperm DNA fragmentation test our RE had done.

We haven't done any IVFs yet.

ChicagoWeded2007 · May 2011

softbalangel:
ChicagoWeded2007:

I'm sorry, I have not been in this situation.

Some more info might help though. How low are your husband's numbers. Why are they recommending this course of action? Have you had failed IVFs before?

My husband has low count and low motility. The last consultation we had with the RE's office was over the phone to get the results of a couple tests. We are meeting with them next week to discuss it some more.

I would assume the embryo banking is recommended due to the sperm DNA fragmentation test our RE had done.

We haven't done any IVFs yet.

I see, it's because of the DNA test. My Uro says he does not rely on that test. If I were you, I would think about just doing regular IVF first. I know there is another bumpie here with the DNA defragmentation test, maybe she will chime in.

May I ask how low the count and motility are and how many SAs you've had to confirm it?

KaliChick · May 2011

Since it's due to dna fragmentation, ask about doing ICSI with PICSI! My lab only charges $200 for PICSI. It is supposed to GREATLY reduce the number of sperm with DNA fragmentation. We are dealing with severe MFI and our RE suggested PICSI because he said it would yield us the best sperm. I don't know if it was a contributing factor or not but all 8 mature eggs fertilized. Now of course, we lost 6 of them between fert and the 5dt but he seems to think that was due to egg quality.

I'd definitely look into doing PICSI. Assuming we'll be doing a second round, we'll definitely do PICSI again.

Gregermis · May 2011

So sorry that you have to make such a tough decision! I can't offer any advice, but I wanted to wish you luck with whatever you choose!

softbalangel · May 2011

ChicagoWeded2007:
softbalangel:
ChicagoWeded2007:

I'm sorry, I have not been in this situation.

Some more info might help though. How low are your husband's numbers. Why are they recommending this course of action? Have you had failed IVFs before?

My husband has low count and low motility. The last consultation we had with the RE's office was over the phone to get the results of a couple tests. We are meeting with them next week to discuss it some more.

I would assume the embryo banking is recommended due to the sperm DNA fragmentation test our RE had done.

We haven't done any IVFs yet.

I see, it's because of the DNA test. My Uro says he does not rely on that test. If I were you, I would think about just doing regular IVF first. I know there is another bumpie here with the DNA defragmentation test, maybe she will chime in.

May I ask how low the count and motility are and how many SAs you've had to confirm it?

His last SA showed motility at 27% and morpology at 3%. I can not remember what his count was, but it was slightly higher than his 2 previous SA's. He has done 3 SA's over the course of the last 6 months.

ChicagoWeded2007 · May 2011

softbalangel:
ChicagoWeded2007:
softbalangel:
ChicagoWeded2007:

I'm sorry, I have not been in this situation.

Some more info might help though. How low are your husband's numbers. Why are they recommending this course of action? Have you had failed IVFs before?

My husband has low count and low motility. The last consultation we had with the RE's office was over the phone to get the results of a couple tests. We are meeting with them next week to discuss it some more.

I would assume the embryo banking is recommended due to the sperm DNA fragmentation test our RE had done.

We haven't done any IVFs yet.

I see, it's because of the DNA test. My Uro says he does not rely on that test. If I were you, I would think about just doing regular IVF first. I know there is another bumpie here with the DNA defragmentation test, maybe she will chime in.

May I ask how low the count and motility are and how many SAs you've had to confirm it?

His last SA showed motility at 27% and morpology at 3%. I can not remember what his count was, but it was slightly higher than his 2 previous SA's. He has done 3 SA's over the course of the last 6 months.

That doesn't sound too bad, really. Wouldn't ICSI solve all that?

softbalangel · May 2011

ChicagoWeded2007:
softbalangel:
ChicagoWeded2007:
softbalangel:
ChicagoWeded2007:

His last SA showed motility at 27% and morpology at 3%. I can not remember what his count was, but it was slightly higher than his 2 previous SA's. He has done 3 SA's over the course of the last 6 months.

That doesn't sound too bad, really. Wouldn't ICSI solve all that?

That was my initial thought as well. I just wanted to make sure that my line of thinking was inline with what others thought. I appreciate your opinion.

KaliChick · May 2011

We had less than 1% morph and ICSI solved it for us. If it's the DNA fragmentation, ask about PICSI! Trust me on this one!!

softbalangel · May 2011

KaliChick:
We had less than 1% morph and ICSI solved it for us. If it's the DNA fragmentation, ask about PICSI! Trust me on this one!!

I will ask about this. Do you have any recommendations to look for information on PICIS? I want to be as prepared as possible when we meet with the RE next week.

KaliChick · May 2011

https://art.biocoat.com/products.htm

https://murgdan.blogspot.com/2009/06/special-edition-picsi.html

https://www.pragueivf.com/en/art/picsi/

katib77 · May 2011

I agree 28% mot and 3% morph is not that bad. If you fine out or remember his count that would factor in greatly. Kali has given you great info on PICSI that I'd look into. Personally I'd do a straight IVF cycle with Dh's sperm but them again I can't help but use my numbers in my head when coming to this conclusion. If his count is over say 8 to 10 million then I'd go for it with Kali's PICSI suggestion. If it's only like 5 mil then may I'd agree with your doc - but then again I don't know anything about DNA fragmentation as that has not been brought up in discussion as being a factor in our MFI.

softbalangel · May 2011

katib77:
I agree 28% mot and 3% morph is not that bad. If you fine out or remember his count that would factor in greatly. Kali has given you great info on PICSI that I'd look into. Personally I'd do a straight IVF cycle with Dh's sperm but them again I can't help but use my numbers in my head when coming to this conclusion. If his count is over say 8 to 10 million then I'd go for it with Kali's PICSI suggestion. If it's only like 5 mil then may I'd agree with your doc - but then again I don't know anything about DNA fragmentation as that has not been brought up in discussion as being a factor in our MFI.

For some reason I keep thinking his count was around 14 million. I will have to double check when I get home.

ChicagoWeded2007 · May 2011

softbalangel:

katib77:
I agree 28% mot and 3% morph is not that bad. If you fine out or remember his count that would factor in greatly. Kali has given you great info on PICSI that I'd look into. Personally I'd do a straight IVF cycle with Dh's sperm but them again I can't help but use my numbers in my head when coming to this conclusion. If his count is over say 8 to 10 million then I'd go for it with Kali's PICSI suggestion. If it's only like 5 mil then may I'd agree with your doc - but then again I don't know anything about DNA fragmentation as that has not been brought up in discussion as being a factor in our MFI.

For some reason I keep thinking his count was around 14 million. I will have to double check when I get home.

Well, 14 million is also not that bad. Have you really only been trying since January? And I would think that you could try IUIs first...

mtlaurel · May 2011

I'm not familiar with the DNA fragmentation test, but with those numbers, I don't see why IVF isn't suitable. My H's morph is better, but his counts and motility are lower than that, and we're starting to talk IVF with urologist and RE.

Good luck.

softbalangel · May 2011

ChicagoWeded2007:
softbalangel:

katib77:
I agree 28% mot and 3% morph is not that bad. If you fine out or remember his count that would factor in greatly. Kali has given you great info on PICSI that I'd look into. Personally I'd do a straight IVF cycle with Dh's sperm but them again I can't help but use my numbers in my head when coming to this conclusion. If his count is over say 8 to 10 million then I'd go for it with Kali's PICSI suggestion. If it's only like 5 mil then may I'd agree with your doc - but then again I don't know anything about DNA fragmentation as that has not been brought up in discussion as being a factor in our MFI.

For some reason I keep thinking his count was around 14 million. I will have to double check when I get home.

Well, 14 million is also not that bad. Have you really only been trying since January? And I would think that you could try IUIs first...

I just looked at the paperwork and his count was only 6.5 million. My H had a really bad testicular injury when he was younger and when we started talking about TTC he went and seen a urologist. I had no idea he had a SA done until he got the results. I went off birth control in January after we were told by two RE's and the urologist that are best chance of conceiving was with IVF. I was put on birth control for medical reasons when I was younger, so I was a little hesitant to come off the pill.

Both RE's we met with said that IUI wasn't an option for us. The RE we choose feels that my H's low numbers aren't caused by his injury and are in a decline. We are just trying to be proactive with the information we have.

ChicagoWeded2007 · May 2011

softbalangel:
ChicagoWeded2007:
softbalangel:

katib77:
I agree 28% mot and 3% morph is not that bad. If you fine out or remember his count that would factor in greatly. Kali has given you great info on PICSI that I'd look into. Personally I'd do a straight IVF cycle with Dh's sperm but them again I can't help but use my numbers in my head when coming to this conclusion. If his count is over say 8 to 10 million then I'd go for it with Kali's PICSI suggestion. If it's only like 5 mil then may I'd agree with your doc - but then again I don't know anything about DNA fragmentation as that has not been brought up in discussion as being a factor in our MFI.

For some reason I keep thinking his count was around 14 million. I will have to double check when I get home.

Well, 14 million is also not that bad. Have you really only been trying since January? And I would think that you could try IUIs first...

I just looked at the paperwork and his count was only 6.5 million. My H had a really bad testicular injury when he was younger and when we started talking about TTC he went and seen a urologist. I had no idea he had a SA done until he got the results. I went off birth control in January after we were told by two RE's and the urologist that are best chance of conceiving was with IVF. I was put on birth control for medical reasons when I was younger, so I was a little hesitant to come off the pill.

Both RE's we met with said that IUI wasn't an option for us. The RE we choose feels that my H's low numbers aren't caused by his injury and are in a decline. We are just trying to be proactive with the information we have.

Yes, that is low, but you only need as many sperm as you get eggs for IVF/ICSI. So, 6.5 million is plenty.

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